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Asymmetric electron transfer in photosynthetic reaction centers

Research Project

Project/Area Number 20H03217
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Review Section Basic Section 43040:Biophysics-related
Research InstitutionThe University of Tokyo

Principal Investigator

Ishikita Hiroshi  東京大学, 先端科学技術研究センター, 教授 (00508111)

Project Period (FY) 2020-04-01 – 2024-03-31
Project Status Completed (Fiscal Year 2023)
Budget Amount *help
¥17,550,000 (Direct Cost: ¥13,500,000、Indirect Cost: ¥4,050,000)
Fiscal Year 2022: ¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2021: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2020: ¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Keywords人工光合成 / プロトン移動 / 電子移動 / タンパク質 / X線結晶構造解析 / 水分解酸素発生 / 電荷分離 / 結晶構造 / 光化学系II / プロトン共役電子移動 / 水分解・酸素発生
Outline of Research at the Start

本研究では、蛋白質結晶構造に理論化学的手法を駆使し実施する。電子移動経路中のクロロフィル分子間のカップリング、励起サイトエナジー、1電子還元・1電子酸化電位、電荷分離状態等を評価し定常状態だけでなく励起状態の解析も行う。(PbRC, PSIIとは異なり)対称的に配置される2つの電子移動経路共に電子移動が起こるPhotosystem I (PSI)もあわせて同一の解析を実施することで、PbRC, PSIIの蛋白質環境・蛋白質分子構造因子の寄与を浮き彫りにする。さらに(同じ非対称電子移動の枠組みで語られる)PbRC, PSII間でも、大きく異なると示唆されている両者の電荷分離機構の解明も目指す。

Outline of Final Research Achievements

A theoretical chemical study on electron transfer in photosynthetic reaction center proteins was conducted. In type-I reaction centers, the redox potentials of two electron transfer pathways mediated by chlorophyll in the heliobacteria reaction center (HbRC) and the reaction center derived from green sulfur bacteria (GsbRC) were elucidated. Despite all being called type I reaction centers, including photosystem I (PSI), it was revealed that the redox potentials, specifically the redox potentials between cofactors, differ significantly among them. This finding was published in a paper. Additionally, research on iron-sulfur clusters was carried out, and the results were also published in papers.

Academic Significance and Societal Importance of the Research Achievements

紅色光合成細菌の反応中心(PbRC)、Photosystem II(PSII)、Photosystem I(PSI)では、光励起・電荷分離反応を介してエネルギー変換反応を行う。PbRC, PSIIにおける「(構造の)対称性の中における(電子の振る舞いの)非対称性」という疑問は、「PbRC三次元構造の決定」(ノーベル化学賞、1988年)によって鮮明に打ち出された。数年後のMarcusによる「電子移動反応理論への貢献」(ノーベル化学賞、1992年)といった有用な理論の出現もあった。本研究の結果は、これら基礎自然科学の長年の問いへの分子化学の観点からの解となる。

Report

(4 results)
  • 2023 Final Research Report ( PDF )
  • 2022 Annual Research Report
  • 2021 Annual Research Report
  • 2020 Annual Research Report
  • Research Products

    (86 results)

All 2022 2021 2020

All Journal Article (40 results) (of which Int'l Joint Research: 6 results,  Peer Reviewed: 40 results,  Open Access: 36 results) Presentation (46 results) (of which Int'l Joint Research: 5 results,  Invited: 5 results)

  • [Journal Article] Proton transfer and conformational changes along the hydrogen bond network in heliorhodopsin2022

    • Author(s)
      Tsujimura Masaki、Chiba Yoshihiro、Saito Keisuke、Ishikita Hiroshi
    • Journal Title

      Communications Biology

      Volume: 5 Issue: 1 Pages: 1336-1336

    • DOI

      10.1038/s42003-022-04311-x

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Electron Transfer Route between Quinones in Type-II Reaction Centers2022

    • Author(s)
      Sugo Yu、Tamura Hiroyuki、Ishikita Hiroshi
    • Journal Title

      The Journal of Physical Chemistry B

      Volume: 126 Issue: 46 Pages: 9549-9558

    • DOI

      10.1021/acs.jpcb.2c05713

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Mechanism of Absorption Wavelength Shift of Bacteriorhodopsin During Photocycle2022

    • Author(s)
      Noji Tomoyasu、Ishikita Hiroshi
    • Journal Title

      The Journal of Physical Chemistry B

      Volume: 126 Issue: 48 Pages: 9945-9955

    • DOI

      10.1021/acs.jpcb.2c04359

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Energetics of the Electron Transfer Pathways in the Homodimeric Photosynthetic Reaction Center2022

    • Author(s)
      Kanda Tomoki、Ishikita Hiroshi
    • Journal Title

      Biochemistry

      Volume: 61 Issue: 22 Pages: 2621-2627

    • DOI

      10.1021/acs.biochem.2c00524

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Protonation structure of the closed-cubane conformation of the O2-evolving complex in photosystem II2022

    • Author(s)
      Saito Keisuke、Mino Hiroyuki、Nishio Shunya、Ishikita Hiroshi
    • Journal Title

      PNAS Nexus

      Volume: 1 Issue: 5 Pages: 221-221

    • DOI

      10.1093/pnasnexus/pgac221

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Proton-mediated photoprotection mechanism in photosystem II2022

    • Author(s)
      Sugo Yu、Ishikita Hiroshi
    • Journal Title

      Frontiers in Plant Science

      Volume: 13 Pages: 934736-934736

    • DOI

      10.3389/fpls.2022.934736

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] A self-assembled coordination cage enhances the reactivity of confined amides <i>via</i> mechanical bond-twisting2022

    • Author(s)
      Tamura Hiroyuki、Takezawa Hiroki、Fujita Makoto、Ishikita Hiroshi
    • Journal Title

      Physical Chemistry Chemical Physics

      Volume: 24 Issue: 35 Pages: 21367-21371

    • DOI

      10.1039/d2cp03126d

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed
  • [Journal Article] D139N mutation of PsbP enhances the oxygen-evolving activity of photosystem II through stabilized binding of a chloride ion2022

    • Author(s)
      Imaizumi Ko、Nishimura Taishi、Nagao Ryo、Saito Keisuke、Nakano Takeshi、Ishikita Hiroshi、Noguchi Takumi、Ifuku Kentaro
    • Journal Title

      PNAS Nexus

      Volume: 1 Issue: 3

    • DOI

      10.1093/pnasnexus/pgac136

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Conformational Changes and H-Bond Rearrangements during Quinone Release in Photosystem II2022

    • Author(s)
      Sugo Yu、Saito Keisuke、Ishikita Hiroshi
    • Journal Title

      Biochemistry

      Volume: 61 Issue: 17 Pages: 1836-1843

    • DOI

      10.1021/acs.biochem.2c00324

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Correlation between C?O Stretching Vibrational Frequency and p<i>K</i><sub>a</sub> Shift of Carboxylic Acids2022

    • Author(s)
      Saito Keisuke、Xu Tianyang、Ishikita Hiroshi
    • Journal Title

      The Journal of Physical Chemistry B

      Volume: 126 Issue: 27 Pages: 4999-5006

    • DOI

      10.1021/acs.jpcb.2c02193

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Release of a Proton and Formation of a Low-Barrier Hydrogen Bond between Tyrosine D and D2-His189 in Photosystem II2022

    • Author(s)
      Mandal Manoj、Saito Keisuke、Ishikita Hiroshi
    • Journal Title

      ACS Physical Chemistry Au

      Volume: 2 Issue: 5 Pages: 423-429

    • DOI

      10.1021/acsphyschemau.2c00019

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Absorption wavelength along chromophore low-barrier hydrogen bonds2022

    • Author(s)
      Tsujimura Masaki、Tamura Hiroyuki、Saito Keisuke、Ishikita Hiroshi
    • Journal Title

      iScience

      Volume: 25 Issue: 5 Pages: 104247-104247

    • DOI

      10.1016/j.isci.2022.104247

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Mechanism of Mixed-Valence Fe<sup>2.5+</sup>・・・Fe<sup>2.5+</sup> Formation in Fe<sub>4</sub>S<sub>4</sub> Clusters in the Ferredoxin Binding Motif2022

    • Author(s)
      Kanda Tomoki、Saito Keisuke、Ishikita Hiroshi
    • Journal Title

      The Journal of Physical Chemistry B

      Volume: 126 Issue: 16 Pages: 3059-3066

    • DOI

      10.1021/acs.jpcb.2c01320

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Release of Electrons and Protons from Substrate Water Molecules at the Oxygen-Evolving Complex in Photosystem II2022

    • Author(s)
      Mandal Manoj、Saito Keisuke、Ishikita Hiroshi
    • Journal Title

      Journal of the Physical Society of Japan

      Volume: 91 Issue: 9 Pages: 091012-091012

    • DOI

      10.7566/jpsj.91.091012

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Structure-guided design enables development of a hyperpolarized molecular probe for the detection of aminopeptidase N activity in vivo2022

    • Author(s)
      Yutaro Saito, Hiroyuki Yatabe, Iori Tamura, Yohei Kondo, Ryo Ishida, Tomohiro Seki, Keita Hiraga, Akihiro Eguchi, Yoichi Takakusagi, Keisuke Saito, Nobu Oshima, Hiroshi Ishikita, Kazutoshi Yamamoto, Murali C. Krishna, Shinsuke Sando
    • Journal Title

      Science advances

      Volume: 8 Issue: 13

    • DOI

      10.1126/sciadv.abj2667

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Long-Range Electron Tunneling from the Primary to Secondary Quinones in Photosystem II Enhanced by Hydrogen Bonds with a Nonheme Fe Complex2021

    • Author(s)
      Tamura Hiroyuki、Saito Keisuke、Ishikita Hiroshi
    • Journal Title

      The Journal of Physical Chemistry B

      Volume: 125 Issue: 49 Pages: 13460-13466

    • DOI

      10.1021/acs.jpcb.1c09538

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Proton transfer pathway in anion channelrhodopsin-12021

    • Author(s)
      Tsujimura Masaki、Kojima Keiichi、Kawanishi Shiho、Sudo Yuki、Ishikita Hiroshi
    • Journal Title

      eLife

      Volume: 10

    • DOI

      10.7554/elife.72264

    • NAID

      120007183236

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Exploring the Retinal Binding Cavity of Archaerhodopsin-3 by Replacing the Retinal Chromophore With a Dimethyl Phenylated Derivative2021

    • Author(s)
      Tsuneishi Taichi、Takahashi Masataka、Tsujimura Masaki、Kojima Keiichi、Ishikita Hiroshi、Takeuchi Yasuo、Sudo Yuki
    • Journal Title

      Frontiers in Molecular Biosciences

      Volume: 8 Pages: 794948-794948

    • DOI

      10.3389/fmolb.2021.794948

    • NAID

      120007183231

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Structural basis for high selectivity of a rice silicon channel Lsi12021

    • Author(s)
      Saitoh Yasunori、Mitani-Ueno Namiki、Saito Keisuke、Matsuki Kengo、Huang Sheng、Yang Lingli、Yamaji Naoki、Ishikita Hiroshi、Shen Jian-Ren、Ma Jian Feng、Suga Michihiro
    • Journal Title

      Nature Communications

      Volume: 12 Issue: 1 Pages: 6236-6245

    • DOI

      10.1038/s41467-021-26535-x

    • NAID

      120007170514

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] A sublethal ATP11A mutation associated with neurological deterioration causes aberrant phosphatidylcholine flipping in plasma membranes2021

    • Author(s)
      Segawa Katsumori、21人、Nagata Shigekazu
    • Journal Title

      Journal of Clinical Investigation

      Volume: 131 Issue: 18 Pages: 1-17

    • DOI

      10.1172/jci148005

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Electron Acceptor?Donor Iron Sites in the Iron?Sulfur Cluster of Photosynthetic Electron-Transfer Pathways2021

    • Author(s)
      Kanda Tomoki、Saito Keisuke、Ishikita Hiroshi
    • Journal Title

      The Journal of Physical Chemistry Letters

      Volume: 12 Issue: 31 Pages: 7431-7438

    • DOI

      10.1021/acs.jpclett.1c01896

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Mechanism of the formation of proton transfer pathways in photosynthetic reaction centers2021

    • Author(s)
      Sugo Yu、Saito Keisuke、Ishikita Hiroshi
    • Journal Title

      Proceedings of the National Academy of Sciences

      Volume: 118 Issue: 30

    • DOI

      10.1073/pnas.2103203118

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Role of redox-inactive metals in controlling the redox potential of heterometallic manganese?oxido clusters2021

    • Author(s)
      Saito Keisuke、Nakagawa Minesato、Mandal Manoj、Ishikita Hiroshi
    • Journal Title

      Photosynthesis Research

      Volume: 148 Issue: 3 Pages: 153-159

    • DOI

      10.1007/s11120-021-00846-y

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] The origin of unidirectional charge separation in photosynthetic reaction centers: nonadiabatic quantum dynamics of exciton and charge in pigment?protein complexes2021

    • Author(s)
      Tamura Hiroyuki、Saito Keisuke、Ishikita Hiroshi
    • Journal Title

      Chemical Science

      Volume: 12 Issue: 23 Pages: 8131-8140

    • DOI

      10.1039/d1sc01497h

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Two Distinct Oxygen-Radical Conformations in the X-ray Free Electron Laser Structures of Photosystem II2021

    • Author(s)
      Mandal Manoj、Saito Keisuke、Ishikita Hiroshi
    • Journal Title

      The Journal of Physical Chemistry Letters

      Volume: 12 Issue: 16 Pages: 4032-4037

    • DOI

      10.1021/acs.jpclett.1c00814

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Nature of Asymmetric Electron Transfer in the Symmetric Pathways of Photosystem I2021

    • Author(s)
      Mitsuhashi Koji、Tamura Hiroyuki、Saito Keisuke、Ishikita Hiroshi
    • Journal Title

      The Journal of Physical Chemistry B

      Volume: 125 Issue: 11 Pages: 2879-2885

    • DOI

      10.1021/acs.jpcb.0c10885

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Identification of intermediate conformations in the photocycle of the light-driven sodium-pumping rhodopsin KR22021

    • Author(s)
      Tsujimura Masaki、Ishikita Hiroshi
    • Journal Title

      Journal of Biological Chemistry

      Volume: 296 Pages: 100459-100459

    • DOI

      10.1016/j.jbc.2021.100459

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Proton transfer pathway from the oxygen-evolving complex in photosystem II substantiated by extensive mutagenesis2021

    • Author(s)
      Kuroda Hiroshi、Kawashima Keisuke、Ueda Kazuyo、Ikeda Takuya、Saito Keisuke、Ninomiya Ryo、Hida Chisato、Takahashi Yuichiro、Ishikita Hiroshi
    • Journal Title

      Biochimica et Biophysica Acta (BBA) - Bioenergetics

      Volume: 1862 Issue: 1 Pages: 148329-148329

    • DOI

      10.1016/j.bbabio.2020.148329

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Mechanism of absorption wavelength shifts in anion channelrhodopsin-1 mutants2021

    • Author(s)
      Tsujimura Masaki、Noji Tomoyasu、Saito Keisuke、Kojima Keiichi、Sudo Yuki、Ishikita Hiroshi
    • Journal Title

      Biochimica et Biophysica Acta (BBA) - Bioenergetics

      Volume: 1862 Issue: 2 Pages: 148349-148349

    • DOI

      10.1016/j.bbabio.2020.148349

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Vectorial Proton Transport Mechanism of RxR, a Phylogenetically Distinct and Thermally Stable Microbial Rhodopsin2020

    • Author(s)
      Kojima Keiichi、Ueta Tetsuya、Noji Tomoyasu、Saito Keisuke、Kanehara Kanae、Yoshizawa Susumu、Ishikita Hiroshi、Sudo Yuki
    • Journal Title

      Scientific Reports

      Volume: 10 Issue: 1 Pages: 1-11

    • DOI

      10.1038/s41598-019-57122-2

    • NAID

      120006884916

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Quenching of Singlet Oxygen by Carotenoids via Ultrafast Superexchange Dynamics2020

    • Author(s)
      Tamura Hiroyuki、Ishikita Hiroshi
    • Journal Title

      The Journal of Physical Chemistry A

      Volume: 124 Issue: 25 Pages: 5081-5088

    • DOI

      10.1021/acs.jpca.0c02228

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Acquirement of water-splitting ability and alteration of the charge-separation mechanism in photosynthetic reaction centers2020

    • Author(s)
      Tamura Hiroyuki、Saito Keisuke、Ishikita Hiroshi
    • Journal Title

      Proceedings of the National Academy of Sciences

      Volume: 117 Issue: 28 Pages: 16373-16382

    • DOI

      10.1073/pnas.2000895117

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Rigidly hydrogen-bonded water molecules facilitate proton transfer in photosystem II2020

    • Author(s)
      Sakashita Naoki、Ishikita Hiroshi、Saito Keisuke
    • Journal Title

      Physical Chemistry Chemical Physics

      Volume: 22 Issue: 28 Pages: 15831-15841

    • DOI

      10.1039/d0cp00295j

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] pKa of the ligand water molecules in the oxygen-evolving Mn4CaO5 cluster in photosystem II2020

    • Author(s)
      Saito Keisuke、Nakagawa Minesato、Ishikita Hiroshi
    • Journal Title

      Communications Chemistry

      Volume: 3 Issue: 1 Pages: 89-89

    • DOI

      10.1038/s42004-020-00336-7

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Energetics of Ionized Water Molecules in the H-Bond Network near the Ca2+ and Cl? Binding Sites in Photosystem II2020

    • Author(s)
      Saito Keisuke、Mandal Manoj、Ishikita Hiroshi
    • Journal Title

      Biochemistry

      Volume: 59 Issue: 35 Pages: 3216-3224

    • DOI

      10.1021/acs.biochem.0c00177

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Green-Sensitive, Long-Lived, Step-Functional Anion Channelrhodopsin-2 Variant as a High-Potential Neural Silencing Tool2020

    • Author(s)
      Kojima Keiichi、Miyoshi Natsuki、Shibukawa Atsushi、Chowdhury Srikanta、Tsujimura Masaki、Noji Tomoyasu、Ishikita Hiroshi、Yamanaka Akihiro、Sudo Yuki
    • Journal Title

      The Journal of Physical Chemistry Letters

      Volume: 11 Issue: 15 Pages: 6214-6218

    • DOI

      10.1021/acs.jpclett.0c01406

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Dependence of the chlorophyll wavelength on the orientation of a charged group: Why does the accessory chlorophyll have a low site energy in photosystem II?2020

    • Author(s)
      Saito Keisuke、Mitsuhashi Koji、Ishikita Hiroshi
    • Journal Title

      Journal of Photochemistry and Photobiology A: Chemistry

      Volume: 402 Pages: 112799-112799

    • DOI

      10.1016/j.jphotochem.2020.112799

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Redox potentials along the redox-active low-barrier H-bonds in electron transfer pathways2020

    • Author(s)
      Saito Keisuke、Mandal Manoj、Ishikita Hiroshi
    • Journal Title

      Physical Chemistry Chemical Physics

      Volume: 22 Issue: 44 Pages: 25467-25473

    • DOI

      10.1039/d0cp04265j

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] The Nature of the Short Oxygen?Oxygen Distance in the Mn4CaO6 Complex of Photosystem II Crystals2020

    • Author(s)
      Mandal Manoj、Saito Keisuke、Ishikita Hiroshi
    • Journal Title

      The Journal of Physical Chemistry Letters

      Volume: 11 Issue: 23 Pages: 10262-10268

    • DOI

      10.1021/acs.jpclett.0c02868

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Insights into the Protein Functions and Absorption Wavelengths of Microbial Rhodopsins2020

    • Author(s)
      Tsujimura Masaki、Ishikita Hiroshi
    • Journal Title

      The Journal of Physical Chemistry B

      Volume: 124 Issue: 52 Pages: 11819-11826

    • DOI

      10.1021/acs.jpcb.0c08910

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Presentation] Energetics of time-dependent structural changes in the photosynthetic electron transfer pathway2022

    • Author(s)
      西川 凱、菅生 優、斉藤 圭亮、石北 央
    • Organizer
      第2回システム生物医学研究会
    • Related Report
      2022 Annual Research Report
  • [Presentation] Energetics of proton transfers in the communication channel between two active sites of pyruvate oxidase2022

    • Author(s)
      高見 亮成、斉藤 圭亮、石北 央
    • Organizer
      第2回システム生物医学研究会
    • Related Report
      2022 Annual Research Report
  • [Presentation] Why is the oxygen-evolving complex in photosystem II composed of manganese instead of iron?2022

    • Author(s)
      齊藤 昌弘、斉藤 圭亮、石北 央
    • Organizer
      第2回システム生物医学研究会
    • Related Report
      2022 Annual Research Report
  • [Presentation] Energy transfer pathways in light harvesting complex II2022

    • Author(s)
      鍵本 拓海、斉藤 圭亮、石北 央
    • Organizer
      第2回システム生物医学研究会
    • Related Report
      2022 Annual Research Report
  • [Presentation] Effect of chlorine substitution by iodine in oxygen-evolving photosystem II2022

    • Author(s)
      陳 楊、斉藤 圭亮、石北 央
    • Organizer
      第2回システム生物医学研究会
    • Related Report
      2022 Annual Research Report
  • [Presentation] Extracellular electron transfer pathways in the multi-heme MtrABC complex2022

    • Author(s)
      沖 樹、石北 央
    • Organizer
      第2回システム生物医学研究会
    • Related Report
      2022 Annual Research Report
  • [Presentation] Origin of electron paramagnetic resonance signals from the water-splitting complex in photosystem II2022

    • Author(s)
      西尾 俊哉、斉藤 圭亮、三野 広幸、石北 央
    • Organizer
      第2回システム生物医学研究会
    • Related Report
      2022 Annual Research Report
  • [Presentation] Electron transfer pathways in photosynthetic type-I reaction centers2022

    • Author(s)
      神田 知樹、石北 央
    • Organizer
      第2回システム生物医学研究会
    • Related Report
      2022 Annual Research Report
  • [Presentation] 光・電子・プロトンとタンパク質分子2022

    • Author(s)
      石北 央
    • Organizer
      第26回新学術「高速分子動画」オンラインセミナー
    • Related Report
      2022 Annual Research Report
    • Invited
  • [Presentation] 水分解反応触媒における電子スピン共鳴 シグナルの起源2022

    • Author(s)
      西尾 俊哉、斉藤 圭亮、三野 広幸、石北 央
    • Organizer
      第36回分子シミュレーション大会
    • Related Report
      2022 Annual Research Report
  • [Presentation] タンパク質分子構造と機能をつなぐ光・電子・プロトン2022

    • Author(s)
      石北 央
    • Organizer
      第19回糖鎖科学コンソーシアムシンポジウム
    • Related Report
      2022 Annual Research Report
    • Invited
  • [Presentation] Light absorption, proton transfer, and ion transport in the light-driven sodium-pumping rhodopsin KR22022

    • Author(s)
      Masaki Tsujimura, Hiroshi Ishikita
    • Organizer
      19th International Conference on Retinal Proteins
    • Related Report
      2022 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Origin of electron paramagnetic resonance signals from the water-splitting complex in photosystem II2022

    • Author(s)
      西尾 俊哉、斉藤 圭亮、三野 広幸、石北 央
    • Organizer
      第14回筑波大学計算科学研究センター創立30周年記念シンポジウム
    • Related Report
      2022 Annual Research Report
    • Int'l Joint Research
  • [Presentation] A newly designed hyperpolarized molecular probe enables the in vivo detection of aminopeptidase N activity from the tumor regions in animals2022

    • Author(s)
      Hiroyuki Yatabe, Yutaro Saito, Iori Tamura, Yohei Kondo, Ryo Ishida, Tomohiro Seki, Keita Hiraga, Akihiro Eguchi, Yoichi Takakusagi, Keisuke Saito, Nobu Oshima, Hiroshi Ishikita, Kazutoshi Yamamoto, Murali C. Krishna, Shinsuke Sando
    • Organizer
      WMIC2022
    • Related Report
      2022 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 微生物型ロドプシンの吸収波長とプロトン移動の制御機構2022

    • Author(s)
      辻村 真樹、石北 央
    • Organizer
      第60回日本生物物理学会年会
    • Related Report
      2022 Annual Research Report
  • [Presentation] 光合成反応中心における一方向の励起子電荷分離経路の分子論的起源2022

    • Author(s)
      田村 宏之、斉藤 圭亮、石北 央
    • Organizer
      第16回分子科学討論会
    • Related Report
      2022 Annual Research Report
  • [Presentation] 光合成反応中心における一方向の励起子電荷分離 経路の起源2022

    • Author(s)
      田村 宏之、斉藤 圭亮、石北 央
    • Organizer
      2022年光化学討論会
    • Related Report
      2022 Annual Research Report
  • [Presentation] 酵素反応速度論に立脚したアミノペプチダーゼ活性検出超偏極MRI分子プローブの開発2022

    • Author(s)
      齋藤 雄太朗、谷田部 浩行、田村 伊織、近藤 洋平、石田 諒、関智 宏、平賀 啓太、江口 晃弘、高草木 洋一、斉藤 圭亮、大嶋野 歩、石北 央、山本 和俊、Murali C. Krishna、山東 信介
    • Organizer
      第16回バイオ関連化学シンポジウム
    • Related Report
      2022 Annual Research Report
  • [Presentation] Quinone-mediated electron transfer in type II reaction centers2022

    • Author(s)
      Hiroshi Ishikita
    • Organizer
      18th International Congress on Photosynthesis Research 2022
    • Related Report
      2022 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] タンパク質中におけるプロトン移動と電子移動2022

    • Author(s)
      石北 央
    • Organizer
      物性研短期研究会「理論タンパク質物性科学の最前線:理論と実験との密な協働」
    • Related Report
      2022 Annual Research Report
    • Invited
  • [Presentation] 光受容タンパク質の色素が形成する低障壁水素結合における吸収波長2022

    • Author(s)
      辻村 真樹、田村 宏之、斉藤 圭亮、石北 央
    • Organizer
      第48回生体分子科学討論会
    • Related Report
      2022 Annual Research Report
  • [Presentation] ヘリオロドプシンの水素結合ネットワークと光反応におけるプロトン移動経路の解析2022

    • Author(s)
      千葉 義大、辻村 真樹 、石北 央
    • Organizer
      第22回 日本蛋白質科学会年会
    • Related Report
      2022 Annual Research Report
  • [Presentation] 微生物型ロドプシンにおける光駆動イオン輸送機構の解明2022

    • Author(s)
      辻村 真樹、小島 慧一、須藤 雄気、石北 央
    • Organizer
      第22回 日本蛋白質科学会年会
    • Related Report
      2022 Annual Research Report
  • [Presentation] 塩素イオンの結合安定化を介した光 化学系 II の酸素発生活性の向上2022

    • Author(s)
      今泉 滉、西村 大志、長尾 遼、斉藤 圭亮、中野 雄司、石北 央、野口 巧、伊福 健太郎
    • Organizer
      日本光合成学会年会
    • Related Report
      2022 Annual Research Report
  • [Presentation] イネ由来ケイ酸チャネルによるケイ酸透過機構の構造基盤2021

    • Author(s)
      齊藤 恭紀、三谷-上野 奈見季、斉藤 圭亮、松木 謙悟 、Huang Sheng, Yang Lingli、山地 直樹、石北 央、沈 建仁、馬 建鋒 、菅 倫寛
    • Organizer
      第44回日本分子生物学会年会
    • Related Report
      2021 Annual Research Report
  • [Presentation] Mechanism of the formation of proton transfer pathways in photosynthetic reaction centers2021

    • Author(s)
      Yu Sugo, Keisuke Saito, Hiroshi Ishikita
    • Organizer
      第59回日本生物物理学会年会
    • Related Report
      2021 Annual Research Report
  • [Presentation] Electron acceptor-donor iron sites in the iron-sulfur cluster of photosynthetic electron-transfer pathways2021

    • Author(s)
      神田 知樹、斉藤 圭亮、石北 央
    • Organizer
      第59回日本生物物理学会年会
    • Related Report
      2021 Annual Research Report
  • [Presentation] アニオンチャネルロドプシンのプロトンを介したアニオン透過機構の解明2021

    • Author(s)
      辻村 真樹、小島 慧一、川西 志歩、須藤 雄気、石北 央
    • Organizer
      第59回日本生物物理学会年会
    • Related Report
      2021 Annual Research Report
  • [Presentation] Structural basis for high selectivity of a rice silicic acid channel2021

    • Author(s)
      齊藤 恭紀、三谷-上野 奈見季、斉藤 圭亮、松木 謙悟 、Huang Sheng, Yang Lingli、山地 直樹、石北 央、沈 建仁、馬 建鋒 、菅 倫寛
    • Organizer
      PDBアジア地区50周年記念シンポジウム
    • Related Report
      2021 Annual Research Report
  • [Presentation] 穀物由来ケイ酸チャネルによるケイ酸輸送機構の構造学的研究2021

    • Author(s)
      齊藤 恭紀、三谷-上野 奈見季、斉藤 圭亮、松木 謙悟 、Huang Sheng, Yang Lingli、山地直樹、石北 央、沈 建仁、馬 建鋒 、菅 倫寛
    • Organizer
      膜シンポジウム2021
    • Related Report
      2021 Annual Research Report
  • [Presentation] フリッパーゼの変異による活性への影響2021

    • Author(s)
      平賀 啓太、瀬川 勝盛、野地 智康、石北 央、長田 重一
    • Organizer
      第11回CSJ化学フェスタ2021
    • Related Report
      2021 Annual Research Report
  • [Presentation] タンパク質中における短い水素結合を含むネットワークの探索2021

    • Author(s)
      中利 一輝、斉藤 圭亮、石北 央
    • Organizer
      第11回CSJ化学フェスタ2021
    • Related Report
      2021 Annual Research Report
  • [Presentation] 光合成反応中心におけるプロトン移動経路同定と機能解明2021

    • Author(s)
      菅生 優、斉藤 圭亮、石北 央
    • Organizer
      第11回CSJ化学フェスタ2021
    • Related Report
      2021 Annual Research Report
  • [Presentation] 光化学系Iにおける鉄硫黄錯体を介した特異な電子移動機構2021

    • Author(s)
      神田 知樹、斉藤 圭亮、石北 央
    • Organizer
      第11回CSJ化学フェスタ2021
    • Related Report
      2021 Annual Research Report
  • [Presentation] アニオンチャネルロドプシンにおけるプロトンを介し たアニオン透過機構の解明2021

    • Author(s)
      辻村 真樹、野地 智康、斉藤 圭亮、小島 慧一、須藤 雄気、石北 央
    • Organizer
      第11回CSJ化学フェスタ2021
    • Related Report
      2021 Annual Research Report
  • [Presentation] Electron and proton releasing sites in the oxygen-evolving complex of photosystem II2021

    • Author(s)
      Hiroshi Ishikita
    • Organizer
      19th Congress of the European Society for Photobiology
    • Related Report
      2021 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] タンパク質分子内における酸化還元とプロトン授受2021

    • Author(s)
      石北 央
    • Organizer
      第4回人工光合成研究拠点講演会
    • Related Report
      2021 Annual Research Report
  • [Presentation] 光化学系Iにおける鉄硫黄錯体を介した特異な電子移動機構2021

    • Author(s)
      神田 知樹、斉藤 圭亮、石北 央
    • Organizer
      第28回光合成セミナー
    • Related Report
      2021 Annual Research Report
  • [Presentation] 光合成反応中心におけるプロトン移動経路同定と機能解明2021

    • Author(s)
      菅生 優、斉藤 圭亮、石北 央
    • Organizer
      第28回光合成セミナー
    • Related Report
      2021 Annual Research Report
  • [Presentation] 微生物型ロドプシンにおける吸収波長と分子機能の考察2021

    • Author(s)
      辻村 真樹、石北 央
    • Organizer
      第28回光合成セミナー
    • Related Report
      2021 Annual Research Report
  • [Presentation] バクテリオロドプシンにおける中間体の吸収波長変化の機構2021

    • Author(s)
      野地 智康、石北 央
    • Organizer
      第28回光合成セミナー
    • Related Report
      2021 Annual Research Report
  • [Presentation] 微生物型ロドプシンにおける吸収波長と分子機能の考察2021

    • Author(s)
      辻村 真樹、野地 智康、斉藤 圭亮、小島 慧一、須藤 雄気、石北 央
    • Organizer
      第47回生体分子科学討論会
    • Related Report
      2021 Annual Research Report
  • [Presentation] 光合成反応中心におけるプロトン移動経路同定と機能解明2021

    • Author(s)
      菅生 優、斉藤 圭亮、石北 央
    • Organizer
      第47回生体分子科学討論会
    • Related Report
      2021 Annual Research Report
  • [Presentation] 光合成反応中心におけるプロトン移動経路同定と機能解明2021

    • Author(s)
      菅生 優、斉藤 圭亮、石北 央
    • Organizer
      第11回日本光合成学会年会
    • Related Report
      2021 Annual Research Report
  • [Presentation] ジメチルフェニル誘導体への置換と機能・光化学的解析2021

    • Author(s)
      辻村 真樹、斉藤 圭亮、石北 央
    • Organizer
      第11回日本光合成学会年会
    • Related Report
      2021 Annual Research Report
  • [Presentation] Archaerhodopsin-3 (AR3)における発色団レチナールのジメチルフェニル誘導体への置換と機能・光化学的解析2021

    • Author(s)
      恒石 泰地、辻村 真樹、高橋 雅崇、 小島 慧一、石北 央、 竹内 靖雄、 須藤 雄気
    • Organizer
      生物物理学会・中国四国支部大会
    • Related Report
      2021 Annual Research Report

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Published: 2020-04-28   Modified: 2025-01-30  

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