| Budget Amount *help |
¥17,680,000 (Direct Cost: ¥13,600,000、Indirect Cost: ¥4,080,000)
Fiscal Year 2023: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2022: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2021: ¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2020: ¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
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| Outline of Final Research Achievements |
development and regulating various biological functions, from innate to social behaviors. However, the precise mechanisms for input-dependent neural circuit development remains unclear. By using the mouse olfactory system as a model, this research aimed to uncover how sensory inputs regulate gene expression in neurons and contribute to the development of neural circuits that underlying social behaviors. We found that olfactory inputs regulate gene expression in a developmental stage-specific manner, which forms the basis for the structural and functional development of olfactory circuits. Specifically, we found that olfactory inputs play an important role in the regulation of genes related to emotional behaviors such as fear and anxiety. These findings contribute to our understanding of how sensory inputs regulate gene expression during neural circuit development and the subsequent development of social behavior.
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