| Budget Amount *help |
¥17,810,000 (Direct Cost: ¥13,700,000、Indirect Cost: ¥4,110,000)
Fiscal Year 2022: ¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2021: ¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2020: ¥7,150,000 (Direct Cost: ¥5,500,000、Indirect Cost: ¥1,650,000)
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| Outline of Final Research Achievements |
In hostile situations of social defeat stress, oxytocin-producing neurons in the paraventricular nucleus of the hypothalamus and oxytocin receptor-expressing neurons in the ventromedial hypothalamus were suggested to facilitate social defeat posture, an active coping behavior. In affiliative situations, oxytocin receptor-expressing neurons in different brain regions were activated in parallel with affiliative behaviors. All these data suggest that distinct oxytocin systems play a role in active coping behaviors both in hostile and affiliative situations.
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