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Method for determining spatial resolution with verification in iterative reconstruction CT images

Research Project

Project/Area Number 20K08046
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Review Section Basic Section 52040:Radiological sciences-related
Research InstitutionNiigata University

Principal Investigator

Ohkubo Masaki  新潟大学, 医歯学系, 教授 (10203738)

Co-Investigator(Kenkyū-buntansha) 成田 啓廣  新潟大学, 医歯学系, 助教 (10770208)
Project Period (FY) 2020-04-01 – 2024-03-31
Project Status Completed (Fiscal Year 2023)
Budget Amount *help
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2023: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2022: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2021: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2020: ¥260,000 (Direct Cost: ¥200,000、Indirect Cost: ¥60,000)
KeywordsX線CT装置 / スライス感度分布(SSP) / 逐次近似再構成 / 空間分解能 / 肺がん / コンピュータ支援診断(CAD) / circular edge / line spread function / 変調伝達関数(MTF) / 点広がり関数(PSF) / CT(computed tomography)
Outline of Research at the Start

申請者らはこれまでに空間分解能に基づいたCT画像のコンピュータシミュレーションの理論・技術の開発を進め、バーチャル3D肺がん像を考案した。それらの研究成果は肺がんCT検診の普及につながることが示され、継続的な発展が期待されている。しかし、近年従来のCT画像に代わって新しい逐次近似再構成CT画像“IR画像”が広く普及してきており、申請者らの研究でも対応が必要となった。IR画像の空間分解能はコントラスト雑音比の低い画像から算出する必要があるため解析が難しく、現状では信頼性の高い測定法は確立されていない。本研究では、コントラスト雑音比の低い画像からでも精度の高い空間分解能測定が可能な手法を開発する。

Outline of Final Research Achievements

The computer-simulated nodule image ‘virtual nodule’ had been developed and demonstrated to be useful for evaluating the performance of computer-aided detection of lung cancer CT screening. To apply the virtual nodule to the iterative reconstruction (IR) images, it is necessary to measure the spatial resolution from images of the low-contrast phantom. The purpose of this study was to propose a method for determining the slice sensitivity profile (SSP) of IR images. In the proposed method, the simulation image of a sphere was calculated using a modeled SSP, and the model parameters were optimized so that the simulation image agreed to the actual image of the sphere phantom. The simulation image calculated using the SSP obtained by the proposed method showed a good agreement to the actual image; this is indicating the accuracy of the SSP. The possibility of application of the virtual nodule to the IR images was suggested.

Academic Significance and Societal Importance of the Research Achievements

肺がんの早期発見のためには胸部CT検診およびコンピュータ支援診断(CAD)の普及が必要であり、CADの性能評価が重要となる。申請者らがこれまでに開発したVirtual Noduleを利用することで、各施設においてCADの性能を適確に評価することができるようになる。しかし、Virtual NoduleをIR画像に適用するためには、コントラストの低い画像から空間分解能を測定する必要があり、処理パラメータの設定によっては測定精度が低下する場合もある。本研究で開発したSSP測定法を用いることにより高精度なSSP測定が可能であり、Virtual NoduleのIR画像への適用が可能となる。

Report

(5 results)
  • 2023 Annual Research Report   Final Research Report ( PDF )
  • 2022 Research-status Report
  • 2021 Research-status Report
  • 2020 Research-status Report
  • Research Products

    (19 results)

All 2023 2022 2021 2020

All Journal Article (9 results) (of which Peer Reviewed: 9 results,  Open Access: 7 results) Presentation (10 results)

  • [Journal Article] Method for measuring noise-power spectrum independent of the effect of extracting the region of interest from a noise image2023

    • Author(s)
      Narita Akihiro、Ohsugi Yuki、Ohkubo Masaki、Fukaya Takahiro、Sakai Kenichi、Noto Yoshiyuki
    • Journal Title

      Radiological Physics and Technology

      Volume: 16 Issue: 4 Pages: 471-477

    • DOI

      10.1007/s12194-023-00733-2

    • Related Report
      2023 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Method for Measuring Noise Power Spectrum Depending on X-ray Tube Angle in Spiral Orbit of Helical CT Scan2023

    • Author(s)
      Ohsugi Yuki、Narita Akihiro、Ohkubo Masaki、Sakai Kenichi、Fukaya Takahiro、Noto Yoshiyuki
    • Journal Title

      Japanese Journal of Radiological Technology

      Volume: 79 Issue: 10 Pages: 1144-1150

    • DOI

      10.6009/jjrt.2023-1363

    • ISSN
      0369-4305, 1881-4883
    • Related Report
      2023 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] A Study of 3D-NPS Analysis in CT Images Based on the Central Cross-section Theorem2022

    • Author(s)
      Narita Akihiro、Ohkubo Masaki、Fukaya Takahiro、Sakai Kenichi、Noto Yoshiyuki
    • Journal Title

      Japanese Journal of Radiological Technology

      Volume: 78 Issue: 4 Pages: 342-347

    • DOI

      10.6009/jjrt.2022-1217

    • NAID

      130008163618

    • ISSN
      0369-4305, 1881-4883
    • Related Report
      2022 Research-status Report 2021 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] An Easy-to-use Method for CT Image Simulation with Parameter Optimization Using a Water Phantom2022

    • Author(s)
      Narita Akihiro、Okamoto Kazuki、Toyonaga Kengo、Ohkubo Masaki
    • Journal Title

      Japanese Journal of Radiological Technology

      Volume: 78 Issue: 7 Pages: 732-740

    • DOI

      10.6009/jjrt.2022-1222

    • ISSN
      0369-4305, 1881-4883
    • Related Report
      2022 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] A Study of Longitudinal NPS Measurement in CT Images Based on the Central Cross-section Theorem2022

    • Author(s)
      Narita Akihiro、Ohkubo Masaki、Ohsugi Yuki、Sakai Kenichi、Fukaya Takahiro、Noto Yoshiyuki
    • Journal Title

      Japanese Journal of Radiological Technology

      Volume: 78 Issue: 7 Pages: 719-725

    • DOI

      10.6009/jjrt.2022-1267

    • ISSN
      0369-4305, 1881-4883
    • Related Report
      2022 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] A Simple Method for Computationally Generating Metal Artifacts in CT Images for Treatment Planning: A Pilot Phantom Study2021

    • Author(s)
      Mugishima Daisuke、Narita Akihiro、Ohkubo Masaki
    • Journal Title

      Japanese Journal of Radiological Technology

      Volume: 77 Issue: 5 Pages: 445-453

    • DOI

      10.6009/jjrt.2021_JSRT_77.5.445

    • NAID

      130008040225

    • ISSN
      0369-4305, 1881-4883
    • Related Report
      2021 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Central Slice Theorem-based Relationship between 1D-NPS Obtained by the Slit Method and 2D-NPS for CT Images2021

    • Author(s)
      Narita Akihiro、Ohkubo Masaki、Fukaya Takahiro、Noto Yoshiyuki
    • Journal Title

      Japanese Journal of Radiological Technology

      Volume: 77 Issue: 8 Pages: 828-832

    • DOI

      10.6009/jjrt.2021_JSRT_77.8.828

    • NAID

      130008076331

    • ISSN
      0369-4305, 1881-4883
    • Related Report
      2021 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Method for determining slice sensitivity profile of iterative reconstruction CT images using low-contrast sphere phantom2021

    • Author(s)
      Narita Akihiro、Ohkubo Masaki、Fukaya Takahiro、Noto Yoshiyuki
    • Journal Title

      Radiological Physics and Technology

      Volume: 14 Issue: 4 Pages: 366-372

    • DOI

      10.1007/s12194-021-00636-0

    • Related Report
      2021 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Technical Note: A simple method for measuring the slice sensitivity profile of iteratively reconstructed CT images using a non‐slanted edge plane2021

    • Author(s)
      Narita Akihiro、Ohkubo Masaki、Fukaya Takahiro、Noto Yoshiyuki
    • Journal Title

      Medical Physics

      Volume: 48 Issue: 3 Pages: 1125-1130

    • DOI

      10.1002/mp.14668

    • Related Report
      2020 Research-status Report
    • Peer Reviewed
  • [Presentation] A Study of Longitudinal Noise Power Spectrum Measurement in CT Images Based on the Central Slice Theorem2022

    • Author(s)
      Yuki Ohsugi, Akihiro Narita, Masaki Ohkubo, Takahiro Fukaya, Yoshiyuki Noto
    • Organizer
      第78回日本放射線技術学会総会学術大会
    • Related Report
      2022 Research-status Report 2021 Research-status Report
  • [Presentation] Validation of Simplified CT Image Simulation with Optimization Using Multiple Machines2022

    • Author(s)
      Kengo Toyonaga, Akihiro Narita, Masaki Ohkubo, Kenichi Sakai, Takahiro Fukaya, Yoshiyuki Noto
    • Organizer
      第78回日本放射線技術学会総会学術大会
    • Related Report
      2022 Research-status Report 2021 Research-status Report
  • [Presentation] 空間分解能に基づいたCT画像シミュレーションよるCT撮影時の染料決定方法の考案2022

    • Author(s)
      酒井健一、大久保真樹、成田啓廣、高橋直也、能登義幸
    • Organizer
      第12回東北放射線医療技術学術大会
    • Related Report
      2022 Research-status Report
  • [Presentation] ファントム画像を用いた最適化を伴う簡易的CT画像シミュレータの考案2021

    • Author(s)
      岡本和樹、成田啓廣、大久保真樹
    • Organizer
      第77回日本放射線技術学会総会学術大会
    • Related Report
      2021 Research-status Report 2020 Research-status Report
  • [Presentation] CT画像のNPS測定における中央断面定理に基づいた仮想スリット法の検討2021

    • Author(s)
      大杉勇輝、成田啓廣、大久保真樹、深谷貴広、能登義幸
    • Organizer
      第49回日本放射線技術学会秋季学術大会
    • Related Report
      2021 Research-status Report
  • [Presentation] 逐次近似再構成CT画像における傾斜エッジ法のエッジ角度がスライス感度プロファイル測定精度に及ぼす影響2021

    • Author(s)
      深谷貴広、大久保真樹、成田啓廣、能登義幸
    • Organizer
      第49回日本放射線技術学会秋季学術大会
    • Related Report
      2021 Research-status Report
  • [Presentation] A feasible approach to correct MTF measured by the circular-edge technique with image averaging in iterative reconstruction CT2020

    • Author(s)
      Natsuki Ishizaka、Akihiro Narita、Masaki Ohkubo
    • Organizer
      第119回日本医学物理学会学術大会
    • Related Report
      2020 Research-status Report
  • [Presentation] A simple method for generating metal artifacts on CT image using forward projection2020

    • Author(s)
      Daisuke Mugishima、 Akihiro Narita、 Masaki Ohkubo
    • Organizer
      第119回日本医学物理学会学術大会
    • Related Report
      2020 Research-status Report
  • [Presentation] A method for evaluating the detrending technique in noise power spectrum measurements with a simplified CT image simulation2020

    • Author(s)
      Kazuki Okamoto、 Akihiro Narita、 Masaki Ohkubo
    • Organizer
      第119回日本医学物理学会学術大会
    • Related Report
      2020 Research-status Report
  • [Presentation] 逐次近似再構成CT画像における球体ファントムを用いたSlice Sensitivity Profileの測定2020

    • Author(s)
      深谷貴広、成田啓廣、大久保真樹
    • Organizer
      第76回日本放射線技術学会総会学術大会
    • Related Report
      2020 Research-status Report

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Published: 2020-04-28   Modified: 2025-01-30  

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