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Development of an optical mouse detection device for the treatment of amblyopia caused by nystagmus

Research Project

Project/Area Number 20K09798
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Review Section Basic Section 56060:Ophthalmology-related
Research InstitutionKitasato University

Principal Investigator

Kawamorita Takushi  北里大学, 医療衛生学部, 准教授 (80511899)

Project Period (FY) 2020-04-01 – 2023-03-31
Project Status Completed (Fiscal Year 2022)
Budget Amount *help
¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2022: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2021: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2020: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Keywords眼振 / マウス光学系 / 弱視治療 / 模擬眼 / 視線 / 視覚野 / 発達 / 眼光学 / 弱視 / 光学 / 光学式マウス検出装置
Outline of Research at the Start

先天的に眼振を有している場合(先天性眼振)、網膜中心窩に光刺激が適切に送られないために(像が常に揺れている状態のため)視覚野の発達障害が生じる。このような眼球振盪(以下、眼振)を完全に止めることは難しく、また症例によっては視覚野が発達しないため、眼鏡で矯正しても視力が出ない弱視であることも多い。本研究では、メカニカル、光学的に眼振を補正する機構を提供することで、小児の視覚野の発達障害の抑制を目指す。本研究により、先天性眼振に起因する弱視者の軽減につながる。

Outline of Final Research Achievements

The purpose of this study was to attempt to develop a device that detects the displacement of the line of sight from the object to be viewed (nystagmus volume) caused by nystagmus using the principle of an optical mouse, reflects the nystagmus volume detected by existing electronic displays, and promotes the development of the visual cortex by moving the object to be viewed, thereby forming a clear image on the retina.
We investigated the optical system of an optical mouse and found that developing software based on gaze information from a gaze analyzer was desirable in terms of accuracy, safety, versatility, and cost. We succeeded in moving images and video images in conjunction with eye movement, and were able to make the software compatible with still and moving images, making real-time presentation possible. In the final year of the project, the same mechanism was adopted using a virtual reality system, and development was completed along with an accuracy survey.

Academic Significance and Societal Importance of the Research Achievements

本研究成果の学術的意義は、光学式マウス検出系から着想を得て開発を行い、メカニカル、光学的に眼振を補正する機構を提供することができ、ヴァーチャルリアリティシステムでの使用も可能となった。
社会的な意義は、本研究により、眼振患者の視覚野の発達障害を抑制させ、眼振に起因する弱視者の軽減につながる可能性がある。また本研究の過程にて、眼位異常にも対応できるように改良し、精度、安全性、汎用性、コストの面を両立させて技術を提供できる。

Report

(4 results)
  • 2022 Annual Research Report   Final Research Report ( PDF )
  • 2021 Research-status Report
  • 2020 Research-status Report
  • Research Products

    (31 results)

All 2023 2022 2021 2020

All Journal Article (7 results) (of which Peer Reviewed: 7 results) Presentation (19 results) (of which Invited: 3 results) Book (4 results) Patent(Industrial Property Rights) (1 results)

  • [Journal Article] Cone contrast test-HD: sensitivity and specificity in red-green dichromacy and the impact of age2023

    • Author(s)
      Iizuka Tatsuya、Kawamorita Takushi、Handa Tomoya、Ishikawa Hitoshi
    • Journal Title

      Journal of the Optical Society of America A

      Volume: 40 Issue: 5 Pages: 849-858

    • DOI

      10.1364/josaa.480467

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Analyzing effect of waterclefts on visual functions via optical simulations2022

    • Author(s)
      Seki Y, Kawamorita T, Yamamoto N, Tanigawa T, Mita N, Hatsusaka N, Kubo E, Sasaki H
    • Journal Title

      Invest Ophthal Vis Sci

      Volume: accepted Issue: 2 Pages: 1-11

    • DOI

      10.1167/iovs.63.2.22

    • Related Report
      2022 Annual Research Report 2021 Research-status Report
    • Peer Reviewed
  • [Journal Article] Refractive and visual function changes in twilight conditions2022

    • Author(s)
      Iizuka Tatsuya、Kawamorita Takushi、Handa Tomoya、Ishikawa Hitoshi
    • Journal Title

      PLOS ONE

      Volume: 17 Issue: 4 Pages: 1-11

    • DOI

      10.1371/journal.pone.0267149

    • Related Report
      2022 Annual Research Report 2021 Research-status Report
    • Peer Reviewed
  • [Journal Article] Relationship between intraocular lens refractive index and illuminance distribution on retina in off-axis incident light: simulation study of illumination optics2022

    • Author(s)
      Kawamorita Takushi、Handa Tomoya、Shoji Nobuyuki
    • Journal Title

      Optical Review

      Volume: 29 Issue: 6 Pages: 487-491

    • DOI

      10.1007/s10043-022-00768-7

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed
  • [Journal Article] High visibility conditions in a sunset environment2021

    • Author(s)
      Iizuka T, Kawamorita T, Takenaka C, Tsuji H, Kanai H, Hirai T, Suzuki H, Handa T, Ishikawa H
    • Journal Title

      Applied Sciences

      Volume: 11 Issue: 16 Pages: 1-10

    • DOI

      10.3390/app11167229

    • Related Report
      2021 Research-status Report
    • Peer Reviewed
  • [Journal Article] Factors influencing contrast sensitivity function in eyes with mild cataract2021

    • Author(s)
      Kamiya K, Fujimura F, Kawamorita T, Ando W, Iida Y, Shoji N
    • Journal Title

      J Clin Med

      Volume: 10 Issue: 7 Pages: 1-8

    • DOI

      10.3390/jcm10071506

    • Related Report
      2021 Research-status Report
    • Peer Reviewed
  • [Journal Article] Effects of displays on myopia and possible countermeasures based on epidemiology in Japan2020

    • Author(s)
      Kawamorita T
    • Journal Title

      SID Symposium Digest of Technical Papers

      Volume: 51 Pages: 1-2

    • Related Report
      2020 Research-status Report
    • Peer Reviewed
  • [Presentation] 前眼部検査機器を使いこなす~シャインプルークカメラ~2023

    • Author(s)
      川守田 拓志
    • Organizer
      第127回日本眼科学会総会
    • Related Report
      2022 Annual Research Report
  • [Presentation] わかりやすい眼光学~眼内レンズ編~2023

    • Author(s)
      川守田 拓志
    • Organizer
      第7回GSC in 山口
    • Related Report
      2022 Annual Research Report
  • [Presentation] 老視治療の現状と問題点~眼鏡~2023

    • Author(s)
      川守田 拓志
    • Organizer
      日本老視学会第1回学術総会
    • Related Report
      2022 Annual Research Report
  • [Presentation] 曲面有機ELディスプレイにおける黒基調表示の背景輝度と主観的な見やすさの関係2022

    • Author(s)
      川守田 拓志,飯塚 達也,宮坂 真紀子,松原 慶幸,三摩 紀雄
    • Organizer
      日本自動車技術会2022年秋季大会
    • Related Report
      2022 Annual Research Report
  • [Presentation] 眼内レンズの夢~IOLの視機能~2022

    • Author(s)
      川守田 拓志
    • Organizer
      第58回日本眼光学学会総会
    • Related Report
      2022 Annual Research Report
  • [Presentation] 超低輝度ディスプレイを用いた輝度弁別閾2022

    • Author(s)
      川守田 拓志,安田 哲也,太田 尚志,飯塚 達也,宮坂 真紀子,半田 知也
    • Organizer
      第58回日本眼光学学会総会
    • Related Report
      2022 Annual Research Report
  • [Presentation] 乱視の検査と教育法~乱視の検査と教育法~2022

    • Author(s)
      川守田 拓志
    • Organizer
      第37回JSCRS学術総会
    • Related Report
      2022 Annual Research Report
  • [Presentation] 屈折矯正手術の夜間視機能を考える~瞳孔径が屈折矯正手術後視機能に与える影響~2022

    • Author(s)
      川守田 拓志
    • Organizer
      第37回JSCRS学術総会
    • Related Report
      2022 Annual Research Report
  • [Presentation] 第37回JSCRS学術総会2022

    • Author(s)
      川守田 拓志
    • Organizer
      あたらしい視機能・前眼部検査のポイント~前眼部画像解析~
    • Related Report
      2022 Annual Research Report
  • [Presentation] 屈折を再考する;日本人模型眼の重要性2021

    • Author(s)
      川守田 拓志
    • Organizer
      第57回日本眼光学会総会
    • Related Report
      2021 Research-status Report
  • [Presentation] 多焦点眼内レンズ挿入眼の視機能への影響因子;眼内レンズ偏位とλ角の影響2021

    • Author(s)
      川守田 拓志
    • Organizer
      第36回JSCRS学術総会
    • Related Report
      2021 Research-status Report
  • [Presentation] 乱視の検査と矯正法;乱視の検査と矯正法2021

    • Author(s)
      川守田 拓志
    • Organizer
      第36回JSCRS学術総会
    • Related Report
      2021 Research-status Report
  • [Presentation] 視機能・前眼部評価アップデート;前眼部画像解析2021

    • Author(s)
      川守田 拓志
    • Organizer
      第36回JSCRS学術総会
    • Related Report
      2021 Research-status Report
  • [Presentation] 視機能検査結果と日常生活の接点2021

    • Author(s)
      川守田 拓志
    • Organizer
      第15回さがみ眼科研究会
    • Related Report
      2021 Research-status Report
    • Invited
  • [Presentation] 水晶体の加齢変化・白内障と高次収差2021

    • Author(s)
      川守田拓志
    • Organizer
      第125回日本眼科学会総会
    • Related Report
      2020 Research-status Report
  • [Presentation] 眼から考える交通安全2021

    • Author(s)
      川守田拓志
    • Organizer
      2020年度JAF関東交通安全実行委員会総会
    • Related Report
      2020 Research-status Report
    • Invited
  • [Presentation] 老視の眼光学2020

    • Author(s)
      川守田拓志
    • Organizer
      第59回日本白内障学会総会・第46回水晶体研究会
    • Related Report
      2020 Research-status Report
  • [Presentation] 屈折と視力検査2020

    • Author(s)
      川守田拓志
    • Organizer
      第124回日本眼科学会総会
    • Related Report
      2020 Research-status Report
  • [Presentation] Effects of displays on myopia and possible countermeasures based on epidemiology in Japan2020

    • Author(s)
      Kawamorita T
    • Organizer
      SID Symposium
    • Related Report
      2020 Research-status Report
    • Invited
  • [Book] 眼内レンズの選び方-患者の満足度を高めるコツと方法2022

    • Author(s)
      川守田 拓志(分担執筆)
    • Total Pages
      4
    • Publisher
      文光堂
    • ISBN
      9784830656149
    • Related Report
      2021 Research-status Report
  • [Book] 眼科検査ガイド第3版2022

    • Author(s)
      川守田 拓志(分担執筆)
    • Total Pages
      8
    • Publisher
      文光堂
    • ISBN
      9784830656095
    • Related Report
      2021 Research-status Report
  • [Book] 最新主要文献でみる眼科学レビュー2022

    • Author(s)
      川守田 拓志(分担執筆)
    • Total Pages
      4
    • Publisher
      総合医学社
    • ISBN
      9784883787364
    • Related Report
      2021 Research-status Report
  • [Book] ディスプレイにおける見やすさの要件とその評価手法2021

    • Author(s)
      川守田 拓志(分担執筆)
    • Total Pages
      12
    • Publisher
      株式会社技術情報協会
    • Related Report
      2021 Research-status Report
  • [Patent(Industrial Property Rights)] 視覚情報補正装置、視覚情報補正方法、及びプログラム2021

    • Inventor(s)
      学校法人北里研究所,川守田拓志
    • Industrial Property Rights Holder
      学校法人北里研究所,川守田拓志
    • Industrial Property Rights Type
      特許
    • Filing Date
      2021
    • Related Report
      2021 Research-status Report

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Published: 2020-04-28   Modified: 2024-12-25  

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