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Evaluation by longitudinal site on suppression of calf muscle atrophy at sitting position.

Research Project

Project/Area Number 20K11204
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Review Section Basic Section 59010:Rehabilitation science-related
Research InstitutionKanazawa University

Principal Investigator

YAMAZAKI Toshiaki  金沢大学, 保健学系, 教授 (00220319)

Co-Investigator(Kenkyū-buntansha) 宮地 利明  金沢大学, 保健学系, 教授 (80324086)
大野 直樹  金沢大学, 保健学系, 准教授 (30642219)
宮地 諒  北陸大学, 医療保健学部, 助教 (50847001)
Project Period (FY) 2020-04-01 – 2023-03-31
Project Status Completed (Fiscal Year 2022)
Budget Amount *help
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2022: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2021: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2020: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Keywords下腿筋 / 長軸部位 / 座位 / MRI / 超音波 / 萎縮抑制
Outline of Research at the Start

廃用性筋萎縮予防に関する先行基礎研究の分析対象は、骨格筋の一部または筋線維であった。我々は「骨格筋には解剖学的に起始と停止部があり、全体として機能的に作用する」臨床視点から、長軸部位(近位・筋腹中央・遠位部)による萎縮抑制効果の相違を動物実験で検証してきた。本研究では橋渡し研究の一環として基礎研究に基づくヒトへの応用を進める。具体的には、研究分担者が開発した座位撮像MRIを使い、先行研究で確立した座位時下腿筋評価法の汎用化を図り、超音波画像診断装置による評価の可能性を探る。さらに高齢者施設等で圧倒的に多い座位時間の有効活用を目的に、等尺性収縮による効果的長軸部位を下腿筋の形態面から検証する。

Outline of Final Research Achievements

The purpose was to consider the possibility of evaluation with the ultrasonic diagnostic imaging apparatus using Gravity MRI, and to evaluate the effective longitudinal site due to the isometric contraction in calf muscle morphologically at sitting position.
Results:(1) The difference in conventional MRI image (supine) and Gravity MRI image (sitting) was analyzed.(2) A correlation of ultrasonic and MRI was analyzed. Only 50% part of the medial head of gastrocnemius muscle was correlative.(3) The calf muscle change due to the isometric contraction was tested morphologically at sitting position. The changes were different every muscle.(4) Reliability of the muscle thickness measurement and validity for the cross-sectional area of muscle were enough. As for the muscular strength, the need to put other evaluations together was suggested.

Academic Significance and Societal Importance of the Research Achievements

学術的意義:①機能的作用を鑑み骨格筋全体として効果的に機能を発揮できることが臨床的に重要と考え、長軸部位別に分析した。②研究分担者が開発したGravity MRIを使用し、従来、臥位でしか得られなかった情報を、座位で重力による筋形態変化を詳細に評価した。
社会的意義:①MRIより汎用的な超音波装置による評価の可能性を検証した。②高齢者施設等で圧倒的に多い座位時間の有効活用を想定し、等尺性収縮による下腿筋の形態変化を長軸部位別に検証した。専門職介入時以外の座位時間活用のため、臨床で実施可能な条件下、 長軸部位を考慮した骨格筋全体に効果的な萎縮予防プログラム構築の基礎データを提示した。

Report

(4 results)
  • 2022 Annual Research Report   Final Research Report ( PDF )
  • 2021 Research-status Report
  • 2020 Research-status Report
  • Research Products

    (24 results)

All 2023 2022 2021 2020 Other

All Journal Article (13 results) (of which Peer Reviewed: 13 results,  Open Access: 13 results) Presentation (10 results) Remarks (1 results)

  • [Journal Article] Division of loading time in reloading the disused atrophic soleus muscle induces proximal muscle injury2023

    • Author(s)
      Miyachi Ryo、Morita Yui、Yamazaki Toshiaki
    • Journal Title

      Journal of Physical Therapy Science

      Volume: 35 Issue: 3 Pages: 193-198

    • DOI

      10.1589/jpts.35.193

    • ISSN
      0915-5287, 2187-5626
    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Reliability of lower leg muscle thickness measurement along the long axis of the muscle using ultrasound imaging, in a sitting position2022

    • Author(s)
      Miyachi Ryo、Kanazawa Yuji、Fujii Yoshinari、Ohno Naoki、Miyati Tosiaki、Yamazaki Toshiaki
    • Journal Title

      Journal of Physical Therapy Science

      Volume: 34 Issue: 7 Pages: 515-521

    • DOI

      10.1589/jpts.34.515

    • ISSN
      0915-5287, 2187-5626
    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Relationship between ankle-joint angle during dynamic balance task and ankle-joint proprioception in chronic ankle-instability individuals2022

    • Author(s)
      MIYACHI Ryo、KANAZAWA Yuji、FUJII Yoshinari、YAMAZAKI Toshiaki
    • Journal Title

      The Journal of Sports Medicine and Physical Fitness

      Volume: 63 Issue: 1

    • DOI

      10.23736/s0022-4707.22.13985-x

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Relationship between pelvic floor muscle function and changes in lumbar spine and hip motion due to pelvic floor muscle contraction.2022

    • Author(s)
      Miyachi R, Madokoro S, Ohno N, Miyati T, Yamazaki T
    • Journal Title

      J Back Musculoskelet Rehabil.

      Volume: - Issue: 3 Pages: 1-8

    • DOI

      10.3233/bmr-220240

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Development of evaluation method of pressure redistribution function of pressure distribution mattress: Examination of magnetic resonance image method for visualizing deformation of urethane foam mattress2022

    • Author(s)
      熊谷 あゆ美、大野 直樹、須釜 淳子
    • Journal Title

      Journal of Nursing Science and Engineering

      Volume: 9 Issue: 0 Pages: 136-142

    • DOI

      10.24462/jnse.9.0_136

    • NAID

      130008165174

    • ISSN
      2188-4323, 2432-6283
    • Related Report
      2021 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Preventive effect of weight-bearing in disuse muscle atrophy of diabetic rats2021

    • Author(s)
      Madokoro Sachiko、Inaoka Pleiades Tiharu、Tanaka Shoji、Yamazaki Toshiaki.
    • Journal Title

      Journal of wellness and health care

      Volume: 45 Issue: 1 Pages: 33-40

    • DOI

      10.24517/00063402

    • NAID

      120007124011

    • ISSN
      2434-1509
    • URL

      https://kanazawa-u.repo.nii.ac.jp/records/57132

    • Year and Date
      2021-08-02
    • Related Report
      2021 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Effect of Loading Frequency on the Recovery Process of Disuse Muscle Atrophy2021

    • Author(s)
      MORITA Yui、MIYACHI Ryo、YAMAZAKI Toshiaki
    • Journal Title

      Rigakuryoho Kagaku

      Volume: 36 Issue: 3 Pages: 463-466

    • DOI

      10.1589/rika.36.463

    • NAID

      130008054459

    • ISSN
      1341-1667, 2434-2807
    • Related Report
      2021 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Blood lipid profile changes in type 2 diabetic rats after tail suspension and reloading2021

    • Author(s)
      Tanaka Shoji、Madokoro Sachiko、Inaoka Pleiades Tiharu、Yamazaki Toshiaki
    • Journal Title

      Lipids in Health and Disease

      Volume: 20 Issue: 1 Pages: 1-10

    • DOI

      10.1186/s12944-021-01511-y

    • Related Report
      2021 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Gravity magnetic resonance imaging measurement of muscle pump change accompanied by aging and posture2021

    • Author(s)
      Fujii Taiga、Ohno Naoki、Sawazaki Takuto、Ogura Kohei、Miyati Tosiaki、Sugama Junko
    • Journal Title

      Japan Journal of Nursing Science

      Volume: e12407 Issue: 3

    • DOI

      10.1111/jjns.12407

    • NAID

      210000177711

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Relationship between Muscle Cross-Sectional Area by MRI and Muscle Thickness by Ultrasonography of the Triceps Surae in the Sitting Position2020

    • Author(s)
      Miyachi Ryo、Yamazaki Toshiaki、Ohno Naoki、Miyati Tosiaki
    • Journal Title

      Healthcare

      Volume: 8 Issue: 2 Pages: 166-166

    • DOI

      10.3390/healthcare8020166

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Fast repetitive stretch suppresses denervation‐induced muscle fibrosis2020

    • Author(s)
      Tanaka Shoji、Inaoka Pleiades Tiharu、Yano Asami、Nakagawa Takao、Yamazaki Toshiaki
    • Journal Title

      Muscle & Nerve

      Volume: 62 Issue: 6 Pages: 746-756

    • DOI

      10.1002/mus.27059

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Morphological changes in the long axis of the lower leg muscles during isometric contraction in the sitting position2020

    • Author(s)
      Miyachi Ryo、Yamazaki Toshiaki、Ohno Naoki、Miyati Tosiaki
    • Journal Title

      Journal of Physical Therapy Science

      Volume: 32 Issue: 12 Pages: 828-832

    • DOI

      10.1589/jpts.32.828

    • NAID

      130007953538

    • ISSN
      0915-5287, 2187-5626
    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Inadequate object positioning and improvement of automatic exposure control system calculations based on an empirical algorithm2020

    • Author(s)
      Furukawa Yasushi、Matsubara Kosuke、Miyati Tosiaki
    • Journal Title

      Physical and Engineering Sciences in Medicine

      Volume: 44 Issue: 1 Pages: 37-44

    • DOI

      10.1007/s13246-020-00949-1

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access
  • [Presentation] 抗重力肢位での超音波画像法による下腿筋筋厚測定の信頼性および妥当性.2022

    • Author(s)
      宮地 諒、金澤佑治、藤井義成、大野直樹、宮地利明、山崎俊明.
    • Organizer
      第59回日本リハビリテーション医学会学術集会
    • Related Report
      2022 Annual Research Report
  • [Presentation] 骨盤底筋収縮による腰椎・股関節運動角度の変化と骨盤底筋機能との関係.2022

    • Author(s)
      宮地 諒、間所祥子、大野直樹、宮地利明、山崎俊明.
    • Organizer
      第10回日本筋骨格系徒手理学療法研究会学術大会.
    • Related Report
      2022 Annual Research Report
  • [Presentation] 糖尿病ラットのヒラメ筋及び長趾伸筋の筋張力低下に再荷重が与える影響2022

    • Author(s)
      間所祥子、田中正二、山崎俊明.
    • Organizer
      第27回日本基礎理学療法学会学術大会.
    • Related Report
      2022 Annual Research Report
  • [Presentation] 不動性筋萎縮後のラットヒラメ筋に対する協働筋腱切除による影響2022

    • Author(s)
      田中正二、間所祥子、山崎俊明.
    • Organizer
      第27回日本基礎理学療法学会学術大会
    • Related Report
      2022 Annual Research Report
  • [Presentation] 下腿三頭筋形態の姿勢による違いおよびMRIと超音波画像法による測定値の関係.2021

    • Author(s)
      宮地 諒、大野直樹、宮地利明、山崎俊明
    • Organizer
      第5回日本リハビリテーション医学会秋季学術集会
    • Related Report
      2021 Research-status Report
  • [Presentation] ラット不動性萎縮筋に対する運動介入の影響2021

    • Author(s)
      田中正二、間所祥子、田中靖人、福本匠人、山崎俊明.
    • Organizer
      第26回日本基礎理学療法学会学術大会.
    • Related Report
      2021 Research-status Report
  • [Presentation] 人工膝関節全置換術後の個別理学療法と個別集団併用型理学療法の比較.2021

    • Author(s)
      杉木竣介、後藤伸介、上地本高、東 利紀、黒田一成、田中正二、山崎俊明
    • Organizer
      第9回日本運動器理学療法学会学術大会.
    • Related Report
      2021 Research-status Report
  • [Presentation] 要支援高齢者における生活空間の自立度と中等度強度以上の身体活動(MVPA)との関連.2021

    • Author(s)
      相馬夏月、内山圭太、横川正美、三秋泰一、間所祥子、山崎俊明
    • Organizer
      第8回日本地域理学療法学会学術大会
    • Related Report
      2021 Research-status Report
  • [Presentation] 座位での足関節底屈筋等尺性収縮による下腿筋の形態変化.2020

    • Author(s)
      宮地 諒、福島実沙、山崎俊明、大野直樹、宮地利明
    • Organizer
      第57回日本リハビリテーション医学会学術集会
    • Related Report
      2020 Research-status Report
  • [Presentation] 2型糖尿病ラットのヒラメ筋及び長趾伸筋の筋張力に尾部懸垂が与える影響2020

    • Author(s)
      間所祥子、田中正二、山崎俊明.
    • Organizer
      第25回日本基礎理学療法学会学術大会
    • Related Report
      2020 Research-status Report
  • [Remarks] 金沢大学医薬保健学類理学療法学専攻ホームページ

    • URL

      https://phys-ther.w3.kanazawa-u.ac.jp

    • Related Report
      2021 Research-status Report 2020 Research-status Report

URL: 

Published: 2020-04-28   Modified: 2024-01-30  

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