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Association of Physical Activity and Physical Function with the Relationship Between Depressed Mood-Inflammation in Older Adults.

Research Project

Project/Area Number 20K11327
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Review Section Basic Section 59020:Sports sciences-related
Research InstitutionTokyo Metropolitan Geriatric Hospital and Institute of Gerontology

Principal Investigator

Yoshida Yuko  地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 東京都健康長寿医療センター研究所, 研究員 (30321871)

Co-Investigator(Kenkyū-buntansha) 岩佐 一  福島県立医科大学, 医学部, 准教授 (60435716)
Project Period (FY) 2020-04-01 – 2024-03-31
Project Status Completed (Fiscal Year 2023)
Budget Amount *help
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2022: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2021: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2020: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywords高齢者 / 運動習慣 / 身体活動 / 身体機能 / 炎症 / 精神的健康 / 運動
Outline of Research at the Start

高齢者の精神的健康の低下は、自立度の低下や死亡率の増加を誘発する。また、精神的健康の低下は体内の炎症を伴うが、高齢期の炎症は、心血管系疾患の発生や死亡のリスク要因である。これまでの研究により、運動習慣が抑うつ傾向を抑制すること、身体機能が高いと炎症が低いことを報告している。本研究ではこれらをふまえ、高齢期における運動、炎症反応、精神的健康の関連について検討する。

Outline of Final Research Achievements

The results showed that there was a negative correlation between physical function and inflammation, and that leisure activities moderated poor mental health in older adults living alone. Data were collected to examine the interactions between physical activity and physical function, inflammation, and mental health. Data are currently being analyzed and results will be published in due course. In addition, data were collected to examine psychosocial factors associated with mental health in older adults. Results suggest that social network, somatic complaints, and personality traits are associated with mental health. Further analysis will be conducted and the results will be published.

Academic Significance and Societal Importance of the Research Achievements

高齢期の運動や身体機能と炎症-精神的健康との一連の関連を検討することで、運動が抑うつ傾向を予防する機序のひとつを明らかにすることができる。今後さらに検討を加え、高齢期の精神的健康の低下の予防策の作成に寄与する。

Report

(5 results)
  • 2023 Annual Research Report   Final Research Report ( PDF )
  • 2022 Research-status Report
  • 2021 Research-status Report
  • 2020 Research-status Report
  • Research Products

    (8 results)

All 2023 2022 2021 2020

All Journal Article (3 results) (of which Peer Reviewed: 3 results,  Open Access: 1 results) Presentation (5 results)

  • [Journal Article] Association between Neutrophil-to-Lymphocyte Ratio and Physical Function in Older Adults: A Community-Based Cross-Sectional Study in Japan2022

    • Author(s)
      Yuko Yoshida, Hajime Iwasa, Hunkyung Kim, Takao Suzuki
    • Journal Title

      Int J Environ Res Public Health

      Volume: 19 Issue: 15 Pages: 8996-8996

    • DOI

      10.3390/ijerph19158996

    • Related Report
      2022 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Leisure activity moderates the relationship between living alone and mental health among J apanese older adults2021

    • Author(s)
      Yoshida Yuko、Iwasa Hajime、Ishioka Yoshiko、Suzukamo Yoshimi
    • Journal Title

      Geriatrics & Gerontology International

      Volume: 21 Issue: 5 Pages: 421-425

    • DOI

      10.1111/ggi.14151

    • Related Report
      2020 Research-status Report
    • Peer Reviewed
  • [Journal Article] Personality and health literacy among community‐dwelling older adults living in Japan2020

    • Author(s)
      Iwasa Hajime、Yoshida Yuko
    • Journal Title

      Psychogeriatrics

      Volume: 20 Issue: 6 Pages: 824-832

    • DOI

      10.1111/psyg.12600

    • Related Report
      2020 Research-status Report
    • Peer Reviewed
  • [Presentation] 高齢者における身体活動の実施とその背景要因の検討2023

    • Author(s)
      吉田祐子、岩佐一、鈴鴨よしみ.
    • Organizer
      第72回東北公衆衛生学会総会
    • Related Report
      2023 Annual Research Report
  • [Presentation] 地域在住高齢者における精神的健康とライフスタイル要因の検討2023

    • Author(s)
      吉田祐子、岩佐一、鈴鴨よしみ.
    • Organizer
      第82回日本公衆衛生学会総会
    • Related Report
      2023 Annual Research Report
  • [Presentation] 地域在住高齢者における身体活動と精神的健康の関連2022

    • Author(s)
      吉田祐子、岩佐一
    • Organizer
      第77回 日本体力医学会大会
    • Related Report
      2022 Research-status Report
  • [Presentation] 高齢者の身体機能とneutrophil to lymphocyte ratioとの関連2021

    • Author(s)
      吉田祐子、金憲経、岩佐一、鈴木隆雄.
    • Organizer
      第76回 日本体力医学会大会
    • Related Report
      2021 Research-status Report
  • [Presentation] 高齢者におけるJST版活動能力指標と心身の健康指標の推移との関連 SONIC研究.2020

    • Author(s)
      吉田祐子,増井幸恵,稲垣宏樹,小川まどか,松本清明,鈴木隆雄,池邉一典,神出計,新井康通,権藤恭之,石崎達郎.
    • Organizer
      日本老年社会科学会第62回大会
    • Related Report
      2020 Research-status Report

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Published: 2020-04-28   Modified: 2025-01-30  

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