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Approximation theory and continuation method of nonlocal interactions and its applications

Research Project

Project/Area Number 20K14364
Research Category

Grant-in-Aid for Early-Career Scientists

Allocation TypeMulti-year Fund
Review Section Basic Section 12040:Applied mathematics and statistics-related
Research InstitutionFuture University-Hakodate

Principal Investigator

Tanaka Yoshitaro  公立はこだて未来大学, システム情報科学部, 准教授 (80783977)

Project Period (FY) 2020-04-01 – 2024-03-31
Project Status Completed (Fiscal Year 2023)
Budget Amount *help
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2023: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2022: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2021: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Fiscal Year 2020: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Keywords非局所発展方程式 / 反応拡散系 / 数理モデリング / 空間離散モデル / 空間連続化 / 反応拡散系近似 / 非局所相互作用 / 空間連続化法 / パターン形成 / 拡散誘導不安定化 / 連続化 / 数値シミュレーション / 反応拡散近似 / 離散方程式の連続化
Outline of Research at the Start

近年,対象までの距離によって働きをかえる空間大域的に影響を及ぼす相互作用の存在が実験的に報告された.この相互作用は,数理モデルの中で適当な積分核で記述される.その積分核の形状がわかれば,数値計算から発生するパターンを調べることができるという利点があるが,現象の背後にある因子や機構を調べることは難しい.このことを動機として,本申請課題は,この積分相互作用の数理モデルを反応拡散系で近似し,背後にあるミクロな情報を調べる一つの解析手法の確立を目指す.さらに,多細胞生物の発生現象の数理解析を動機に,積分相互作用を用いて,細胞の大きさと形状を保存する,空間離散モデルを連続化する新たな方法を確立する.

Outline of Final Research Achievements

The interactions which can affect the distant objects globally in space, called nonlocal interactions, are observed in the fields of cell biology, neuroscience and so on. This interaction can be modeled by the convolution with a suitable integral kernel. Many mathematical models with the nonlocal interactions have been proposed. Motivated by the advocate of the application of the nonlocal interactions, this project studied the continuation method with nonlocal interactions conserving the discrete structure and reduction method for the network with spatial interactions. The former continuation method can convert the spatially discretized model into continuous one by using the characteristic function and convolution; this renders both models point-wisely equivalent. The latter method can reduce the network system with arbitrary number of factors into the mathematical model with nonlocal interactions by considering the eigenvalue problems. We published these results as papers.

Academic Significance and Societal Importance of the Research Achievements

積分付き相互作用は,脳の神経の発火現象や動物の表皮に見られる色素パターン,細胞運動を記述することが知られていた.これに加え上記の方法論2つから,多細胞生物の発生現象など空間離散的な構造上で時間発展する現象や,シグナル伝達系や代謝系などの大規模なネットワーク系も積分付き相互作用をもつ数理モデルで記述できることがわかった.さまざまな現象を統一的な視点で扱える枠組みを与えた点において,学術的な意義があると考えている.今後積分付き相互作用をもつ数理モデルの解析を行うことで,さまざまな現象を制御できるようになり,社会的な意義を見出すことができると考えている.

Report

(5 results)
  • 2023 Annual Research Report   Final Research Report ( PDF )
  • 2022 Research-status Report
  • 2021 Research-status Report
  • 2020 Research-status Report
  • Research Products

    (25 results)

All 2024 2023 2022 2021 2020

All Journal Article (7 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 6 results,  Open Access: 6 results) Presentation (18 results) (of which Int'l Joint Research: 4 results,  Invited: 5 results)

  • [Journal Article] Existence of spiky stationary solutions to a mass-conserved reaction-diffusion model2023

    • Author(s)
      Morita Yoshihisa、Tanaka Yoshitaro
    • Journal Title

      Japan Journal of Industrial and Applied Mathematics

      Volume: 41 Issue: 1 Pages: 681-722

    • DOI

      10.1007/s13160-023-00626-2

    • Related Report
      2023 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] 格子や細胞の形状を保存する空間離散モデルの連続化法と応用2023

    • Author(s)
      田中吉太郎,八杉徹雄
    • Journal Title

      日本応用数理学会誌「応用数理」

      Volume: 33

    • Related Report
      2022 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Method of fundamental solutions for Neumann problems of the modified Helmholtz equation in disk domains2021

    • Author(s)
      Shin-Ichiro Ei, Hiroyuki Ochiai, Yoshitaro Tanaka,
    • Journal Title

      Journal of Computational and Applied Mathematics

      Volume: 402 Pages: 113795-113795

    • DOI

      10.1016/j.cam.2021.113795

    • Related Report
      2021 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Intracellular trafficking of Notch orchestrates temporal dynamics of Notch activity in the fly brain2021

    • Author(s)
      Wang Miaoxing、Han Xujun、Liu Chuyan、Takayama Rie、Yasugi Tetsuo、Ei Shin-Ichiro、Nagayama Masaharu、Tanaka Yoshitaro、Sato Makoto
    • Journal Title

      Nature Communications

      Volume: 12 Issue: 1 Pages: 1-15

    • DOI

      10.1038/s41467-021-22442-3

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Effective nonlocal kernels on reaction-diffusion networks2021

    • Author(s)
      Ei Shin-Ichiro、Ishii Hiroshi、Kondo Shigeru、Miura Takashi、Tanaka Yoshitaro
    • Journal Title

      Journal of Theoretical Biology

      Volume: 509 Pages: 110496-110496

    • DOI

      10.1016/j.jtbi.2020.110496

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] A continuation method for spatially discretized models with nonlocal interactions conserving size and shape of cells and lattices2020

    • Author(s)
      Ei Shin-Ichiro、Ishii Hiroshi、Sato Makoto、Tanaka Yoshitaro、Wang Miaoxing、Yasugi Tetsuo
    • Journal Title

      Journal of Mathematical Biology

      Volume: 81 Issue: 4-5 Pages: 981-1028

    • DOI

      10.1007/s00285-020-01534-6

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Reaction-diffusion approximation for understanding pattern formations through non-local interactions2020

    • Author(s)
      田中吉太郎
    • Journal Title

      数理解析研究所講究録2166 第16回生物数学の理論とその応用ー生命現象の定量的理解に向けてー

      Volume: 2166 Pages: 12-16

    • NAID

      40022388054

    • Related Report
      2020 Research-status Report
  • [Presentation] 非局所発展方程式と偏微分方程式系近似について2024

    • Author(s)
      田中吉太郎
    • Organizer
      日本数学会
    • Related Report
      2023 Annual Research Report
    • Invited
  • [Presentation] Keller-Segel type approximation for nonlocal Fokker-Planck equations in one-dimensional bounded domain2023

    • Author(s)
      Yoshitaro Tanaka, Hideki Murakawa
    • Organizer
      RIMS Conference, "Multidisciplinary Research on Nonlinear Phenomena: Modeling, Analysis and Applications”
    • Related Report
      2023 Annual Research Report
    • Invited
  • [Presentation] 1 次元有界領域上の非局所Fokker-Planck方程式に対するKeller-Segel型近似2023

    • Author(s)
      田中吉太郎,村川秀樹
    • Organizer
      日本数学会,2023年度秋季総合分科会
    • Related Report
      2023 Annual Research Report
  • [Presentation] 格子上の空間離散モデルにおけるパターン形成の数理モデリング2023

    • Author(s)
      田中吉太郎,南彩菜
    • Organizer
      第33回日本数理生物学会
    • Related Report
      2023 Annual Research Report
  • [Presentation] Approximation for nonlocal Fokker-Planck equations by a Keller-Segel system2023

    • Author(s)
      Yoshitaro Tanaka, Hideki Murakawa
    • Organizer
      ICIAM 2023
    • Related Report
      2023 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] An approximation by a Keller-Segel system for nonlocal Fokker-Planck equation in bounded one-dimensional domain2023

    • Author(s)
      Yoshitaro Tanaka, Hideki Murakawa
    • Organizer
      The 13th AIMS Conference on Dynamical Systems, Differential Equations and Applications
    • Related Report
      2023 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] A continuation method for spatially discretized models with nonlocal interactions conserving size and shape of cells and lattices2022

    • Author(s)
      Yoshitaro Tanaka, Shin-Ichiro Ei, Hiroshi Ishii, Makoto Sato, Miaoxing Wang, Tetsuo Yasugi,
    • Organizer
      The 12th European Conference on Mathematical and Theoretical Biology
    • Related Report
      2022 Research-status Report
    • Int'l Joint Research
  • [Presentation] 非一様格子上の空間離散モデルにおけるパターン形成の数理モデリング2022

    • Author(s)
      南彩菜,田中吉太郎
    • Organizer
      2022年度応用数学合同研究集会
    • Related Report
      2022 Research-status Report
  • [Presentation] 環境の感知と運動の制御を同時に行う化学反応系ロボットの数理モデリング2022

    • Author(s)
      小田中嵐,田中吉太郎,櫻沢繁
    • Organizer
      日本応用数理学会
    • Related Report
      2022 Research-status Report
  • [Presentation] 非一様格子上の空間離散モデルにおけるパターン形成の数値シミュレーション2022

    • Author(s)
      南彩菜,田中吉太郎
    • Organizer
      日本応用数理学会
    • Related Report
      2022 Research-status Report
  • [Presentation] 環境の感知と運動を同時に制御する化学反応系ロボットの空間1次元の数理モデリング2022

    • Author(s)
      小田中嵐,田中吉太郎,櫻沢繁
    • Organizer
      第32回非線形反応と協同現象研究会
    • Related Report
      2022 Research-status Report
  • [Presentation] A continuation method for spatially discretized models with nonlocal interactions conserving size and shape of cells and its application2021

    • Author(s)
      Yoshitaro Tanaka, Shin-Ichiro Ei, Hiroshi Ishii, Makoto Sato, Miaoxing Wang, Tetsuo Yasugi
    • Organizer
      Modeling and Mathematical Analysis of Dynamics of Patterns,RIMS
    • Related Report
      2021 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] 修正ヘルムホルツ方程式の円領域上の Neumann 問題に対する基本解近似解法2021

    • Author(s)
      栄伸一郎,落合啓之,田中吉太郎
    • Organizer
      日本数学会
    • Related Report
      2021 Research-status Report
  • [Presentation] 円領域内のパルス運動に関わる修正ヘルムホルツ方程式のノイマン問題に対する基本解近似解法2021

    • Author(s)
      栄伸一郎,落合啓之,田中吉太郎
    • Organizer
      日本応用数理学会2021年度年会
    • Related Report
      2021 Research-status Report
  • [Presentation] Belousov-Zhabotinsky 反応を用いたレザバー計算の提案とシミュレーション2021

    • Author(s)
      豊田和人,田中吉太郎、香取勇一、高木清二、櫻沢繁
    • Organizer
      応用数学合同研究集会
    • Related Report
      2021 Research-status Report
  • [Presentation] 1次元格子上の空間離散モデルにおける拡散誘導不安定化2021

    • Author(s)
      南彩菜,田中吉太郎
    • Organizer
      日本数理生物学会
    • Related Report
      2021 Research-status Report
  • [Presentation] 1次元格子上の空間離散モデルにおける拡散誘導不安定化2021

    • Author(s)
      南彩菜,田中吉太郎
    • Organizer
      日本応用数理学会
    • Related Report
      2021 Research-status Report
  • [Presentation] 非局所相互作用による細胞や格子の大きさと形状を保存する空間離散モデルの連続化法2020

    • Author(s)
      田中吉太郎
    • Organizer
      応用数学合同研究集会
    • Related Report
      2020 Research-status Report

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Published: 2020-04-28   Modified: 2025-01-30  

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