• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Investigation of higher visual circuit of telencephalon in fish and searches for visual stimulation attractive for fish

Research Project

Project/Area Number 20K15597
Research Category

Grant-in-Aid for Early-Career Scientists

Allocation TypeMulti-year Fund
Review Section Basic Section 40040:Aquatic life science-related
Research InstitutionNagoya University

Principal Investigator

HAGIO Hanako  名古屋大学, 高等研究院(農), 特任助教 (80848309)

Project Period (FY) 2020-04-01 – 2023-03-31
Project Status Completed (Fiscal Year 2022)
Budget Amount *help
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2022: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2021: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2020: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Keywords視覚 / 魚 / ニューロン / 大脳 / マハゼ / ゼブラフィッシュ / 神経回路 / ハゼ / メダカ / 視覚回路 / 視覚機能 / イメージング
Outline of Research at the Start

学術界や水産業界において魚の視覚への関心が高まっているものの、網膜から大脳に至る視覚路が調べられた魚種は少なく、視覚情報処理については未解明の部分が多い。申請者は視覚路を2つもつ魚もいるが、漁業対象魚の多くは1つだけもつ可能性が高いことをこれまでに明らかにした。大脳に到達した視覚情報は大脳内で更に処理されると考えられるが、そのような回路は全く不明である。そこで、魚の大脳高次視覚回路の解明を行うとともに、視覚性ニューロンがどのような視覚刺激に応答するのかを調べる。また、視覚路が2つの魚と1つの魚の視覚路機能を比較することで、なぜ魚は視覚路を1つだけもつような進化を遂げたのかがわかる可能性もある。

Outline of Final Research Achievements

Although the academia and the fisheries industries are getting interested in the vision of fish, visual pathways from the retina to the telencephalon have been studied only in a small number of fish species, and higher-order visual circuits and their functions in fish are unknown. We investigated the visual circuitries including the higher-order visual circuits in fish, and discovered similarities with mammals. We succeeded in challenging the analyses of visual functions, which have been limited to the retina and mesencephalon around the world, by recording higher-order diencephalic and telencephalic neuronal responses. Furthermore, we have almost established the experimental system for presenting visual stimuli that can be applied to fish for fisheries.

Academic Significance and Societal Importance of the Research Achievements

魚は進化の過程で視覚路が2つから1つになり独自の視覚路の進化を遂げた一方、2つの視覚路をもつ哺乳類と共通している点も多くあることがわかり新しい学術的知見が得られた。また、本研究により世界中で網膜や中脳視蓋にとどまっていた視覚機能解析をより高次な視覚機能解析を行うことを可能にし、魚の視覚機能の解明がより前進することが期待できる。確立できた漁業対象魚にも適用可能な視覚刺激呈示実験系を用いて、ニューロン応答の強い視覚刺激などを見つけ、魚に効果的な視覚刺激を反映した餌や擬餌開発による水産業への貢献が期待できる。

Report

(4 results)
  • 2022 Annual Research Report   Final Research Report ( PDF )
  • 2021 Research-status Report
  • 2020 Research-status Report
  • Research Products

    (27 results)

All 2023 2022 2021 2020 Other

All Int'l Joint Research (3 results) Journal Article (4 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 4 results,  Open Access: 1 results) Presentation (16 results) (of which Int'l Joint Research: 3 results,  Invited: 6 results) Book (2 results) Remarks (2 results)

  • [Int'l Joint Research] CNRS(フランス)

    • Related Report
      2022 Annual Research Report
  • [Int'l Joint Research] CNRS(フランス)

    • Related Report
      2021 Research-status Report
  • [Int'l Joint Research] CNRS(フランス)

    • Related Report
      2020 Research-status Report
  • [Journal Article] Ascending visual pathways to the telencephalon in teleosts with special focus on forebrain visual centers, associated neural circuitries, and evolution2023

    • Author(s)
      Hanako Hagio, Naoyuki Yamamoto
    • Journal Title

      Zoological Science

      Volume: 40 Issue: 2 Pages: 105-118

    • DOI

      10.2108/zs220089

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Morphological analysis of the cerebellum and its efferent system in a basal actinopterygian fish, Polypterus senegalus2022

    • Author(s)
      Ikenaga Takanori、Shimomai Rinko、Hagio Hanako、Kimura Satoru、Matsumoto Kazumasa、Kato Dai‐ichiro、Uesugi Kentaro、Takeuchi Akihisa、Yamamoto Naoyuki、Hibi Masahiko
    • Journal Title

      Journal of Comparative Neurology

      Volume: 530 Issue: 8 Pages: 1231-1246

    • DOI

      10.1002/cne.25271

    • Related Report
      2021 Research-status Report
    • Peer Reviewed
  • [Journal Article] Afferent and efferent connections of the nucleus prethalamicus in the yellowfin goby Acanthogobius flavimanus.2021

    • Author(s)
      Hagio, H., Kawaguchi,M., Abe, H., Yamamoto, N.
    • Journal Title

      J. Comp. Neurol.

      Volume: 529 Issue: 1 Pages: 87-110

    • DOI

      10.1002/cne.24935

    • Related Report
      2020 Research-status Report
    • Peer Reviewed
  • [Journal Article] Non-thalamic origin of zebrafish sensory nuclei implies convergent evolution of visual pathways in amniotes and teleosts2020

    • Author(s)
      Bloch Solal、Hagio Hanako、Thomas Manon、Heuze Aurelie、Hermel Jean-Michel、Lasserre Elodie、Colin Ingrid、Saka Kimiko、Affaticati Pierre、Jenett Arnim、Kawakami Koichi、Yamamoto Naoyuki、Yamamoto Kei
    • Journal Title

      eLife

      Volume: 9 Pages: 1-27

    • DOI

      10.7554/elife.54945

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Presentation] メダカの視覚上行路に見られる哺乳類との共通点2023

    • Author(s)
      〇萩尾華子、山本直之
    • Organizer
      令和5年度日本水産学会春季大会
    • Related Report
      2022 Annual Research Report
  • [Presentation] One ascending visual pathway to the telencephalon in the medaka, a percomorph fish.2022

    • Author(s)
      〇Hagio H, Yamamoto N.
    • Organizer
      J.B. Johnston Club for Evolutionary Neuroscience Annual Meeting
    • Related Report
      2022 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Projection of the diencephalic visual relay nucleus to the telencephalon and presumed higher order, visually-related intra-telencephalic fiber connections in a goby, teleost.2022

    • Author(s)
      〇Hagio H, Yamamoto N.
    • Organizer
      Society for Neuroscience 2022
    • Related Report
      2022 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 漁業対象魚の視覚と視覚機能の進化の研究におけるモデル魚の確立を目指して2022

    • Author(s)
      〇萩尾華子、山本直之
    • Organizer
      第45回日本分子生物学会
    • Related Report
      2022 Annual Research Report
    • Invited
  • [Presentation] ウナギ類の視覚上行路2022

    • Author(s)
      〇渡邊果奈, 山本直之, 萩尾華子
    • Organizer
      令和4年度日本水産学会秋季大会
    • Related Report
      2022 Annual Research Report
  • [Presentation] 魚の高次視覚系の解明とウナギ養殖技術の改善を目指して2022

    • Author(s)
      ○萩尾華子
    • Organizer
      世界的課題を解決する知の『開拓者』育成事業 第1回T-GExコンソーシアム総会
    • Related Report
      2021 Research-status Report
  • [Presentation] 魚の視覚回路の進化および視覚機能の解明を目指して2022

    • Author(s)
      ○萩尾華子
    • Organizer
      令和3年度育志賞研究発表会
    • Related Report
      2021 Research-status Report
  • [Presentation] “もぐもぐ行動”を行うハゼ類の口腔と脳の形態学的研究 Morphological study of the oral cavity and the brain of gobies performing "mogu-mogu behavior"2021

    • Author(s)
      ○萩尾華子、山本直之.
    • Organizer
      第92回日本動物学会オンライン米子大会、サテライトシンポジウム「非モデル生物を材料とした神経行動学のイマとミライ」
    • Related Report
      2021 Research-status Report
    • Invited
  • [Presentation] ニホンウナギの中枢視覚神経路 Central visual pathways in the Japanese eel Anguilla japonica2021

    • Author(s)
      萩尾華子、渡邉果奈、○山本直之.
    • Organizer
      第92回日本動物学会オンライン米子大会、シンポジウム「ウナギへの挑戦、ウナギでの挑戦ーラボからフィールドまで」
    • Related Report
      2021 Research-status Report
    • Invited
  • [Presentation] 魚の視覚回路の進化と味覚による特殊な摂餌行動の制御機構の解明2021

    • Author(s)
      ○萩尾華子
    • Organizer
      第1回名古屋大学イニシアティブウェビナー(高等研究院×未来社会創造機構)~叡智を結集し、未来社会を先導する若手研究者たち~「生命と人工知能(AI)」
    • Related Report
      2021 Research-status Report
    • Invited
  • [Presentation] Studies on the sensory and motor centers of fish and a new interdisciplinary collaborative research2021

    • Author(s)
      ○萩尾華子
    • Organizer
      連携型博士研究人材総合育成システム次世代研究者シンポジウム2021
    • Related Report
      2021 Research-status Report
  • [Presentation] 二ホンウナギの網膜から脳への視覚情報伝達経路の解明2021

    • Author(s)
      萩尾華子, 山本直之
    • Organizer
      東アジア鰻学会・第4回研究発表会
    • Related Report
      2020 Research-status Report
    • Invited
  • [Presentation] ハゼ類に見られる特殊な摂餌行動と口腔形態について2021

    • Author(s)
      梅野祐一朗, 萩尾華子, 岡田央人, 上杉健太朗, 星野真人, 八田公平, 山本直之
    • Organizer
      令和3年度日本水産学会春季大会
    • Related Report
      2020 Research-status Report
  • [Presentation] 魚はどのような神経回路で視覚情報処理をしているのか2021

    • Author(s)
      萩尾華子
    • Organizer
      令和2年度育志賞研究発表会
    • Related Report
      2020 Research-status Report
  • [Presentation] Evolution of visual pathways in teleosts and topographic organization of the tectal projections to the nucleus prethalamicus2020

    • Author(s)
      Hanako Hagio, Naoyuki Yamamoto
    • Organizer
      2020 J.B. Johnston Club for Evolutionary Neuroscience Annual Meeting
    • Related Report
      2020 Research-status Report
    • Int'l Joint Research
  • [Presentation] 魚の視覚回路の解明、そして上位レベルの視覚機能解析を可能に(Investigation of visual circuits in the brain of fish toward the elucidation of higher visual functions)2020

    • Author(s)
      萩尾華子
    • Organizer
      連携型博士研究人材総合育成システム 次世代研究者シンポジウム2020
    • Related Report
      2020 Research-status Report
    • Invited
  • [Book] Brain Development of Medaka Fish: A New Concept of Brain Morphogenesis in Vertebrates2022

    • Author(s)
      Yuji Ishikawa , Naoyuki Yamamoto , Hanako Hagio
    • Total Pages
      256
    • Publisher
      Springer Nature
    • ISBN
      9789811943249
    • Related Report
      2022 Annual Research Report
  • [Book] Cerebellum-like systems in actinopterygian fishes with a special focus on the diversity of cerebellum-like system in the mesencephalon, In “Cerebellum as a CNS Hub”2021

    • Author(s)
      Yamamoto N*, Hagio H.
    • Total Pages
      564
    • Publisher
      Springer
    • Related Report
      2021 Research-status Report
  • [Remarks] 名古屋大学 研究者総覧 萩尾華子

    • URL

      https://profs.provost.nagoya-u.ac.jp/html/100011022_ja.html

    • Related Report
      2022 Annual Research Report 2021 Research-status Report
  • [Remarks] YLC特任助教の萩尾華子先生が第38回井上研究奨励賞を受賞されました

    • URL

      http://www.iar.nagoya-u.ac.jp/performance/1869/

    • Related Report
      2021 Research-status Report

URL: 

Published: 2020-04-28   Modified: 2024-01-30  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi