| Project/Area Number |
20K15838
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| Research Category |
Grant-in-Aid for Early-Career Scientists
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| Allocation Type | Multi-year Fund |
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| Review Section |
Basic Section 44050:Animal physiological chemistry, physiology and behavioral biology-related
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| Research Institution | Tohoku University |
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Principal Investigator |
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| Project Period (FY) |
2020-04-01 – 2025-03-31
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| Project Status |
Granted (Fiscal Year 2023)
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| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2021: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Fiscal Year 2020: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Keywords | Jellyfish / Appetite / Evolution / Feeding / Neuropeptide / Cnidarian / Drosophila / Neurobiology / Bahaviour |
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| Outline of Research at the Start |
Jellyfish have primitive nervous systems, but the mechanisms underlying their behavior are poorly understood. I combine transcriptomics, behavioral and anatomical analyses to find peptides regulating feeding in the a jellyfish. Such peptides will be tested for functional conservation in Drosophila.
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| Outline of Annual Research Achievements |
I have pursued the goals summarized in my previous report (Strategy for Future Research Activity). Specifically, I have: (1) Characterized the behavioral effects of satiety on the feeding behavior of the jellyfish Cladonema, as well as their temporal dynamics and tissue specificity; (2) Characterized the effects of a putative satiety peptide and carried out immunohistochemistry to determine its expression and (3) Expanded the set of candidate peptides using proteomics. Additionally, I have begun looking into the effects of satiety on other jellyfish behaviors, such as locomotion.
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| Current Status of Research Progress |
Current Status of Research Progress
2: Research has progressed on the whole more than it was originally planned.
Reason
While there have been technical setbacks for some experiments, there is good progress in most, and I am currently drafting a manuscript focusing on a detailed characterization of satiety in jellyfish.
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| Strategy for Future Research Activity |
As some experiments have been concluded while others are still ongoing (with promising outcomes), I will focus my efforts towards wrapping up all experiments and the publication of the new results.
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