• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Long-term longitudinal study of the interrelationship between oral and cognitive functions in the older people

Research Project

Project/Area Number 20K18628
Research Category

Grant-in-Aid for Early-Career Scientists

Allocation TypeMulti-year Fund
Review Section Basic Section 57050:Prosthodontics-related
Research InstitutionOsaka University

Principal Investigator

Hatta Kodai  大阪大学, 大学院歯学研究科, 助教 (60845949)

Project Period (FY) 2020-04-01 – 2023-03-31
Project Status Completed (Fiscal Year 2022)
Budget Amount *help
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2021: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2020: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywords口腔機能 / 認知機能 / 高齢者
Outline of Research at the Start

近年,口腔因子と高次脳機能の関連について,様々な結果が報告されているが,多人数を対象とした長期縦断研究はない.そこで本研究においては,自立した生活を送っている高齢者を対象として9年間の縦断研究を行い,口腔因子と高次脳機能ならびにその機能領域別の影響について,明らかにすることを目的とした.本研究では,長期間に複数回の縦断データを用いて,口腔機能を含めた多数の口腔因子と高次脳機能さらには,記憶,言語,見当識,概念的思考,注意機能,視空間認知などの機能領域別の影響について遺伝素因も含めて明らかする.

Outline of Final Research Achievements

This study aimed to investigate how oral factors affect higher brain function and its functional domains in older adults living independently.
The study found that occlusal strength was significantly related to executive function, memory, and attention; masticatory function to memory; tongue pressure to attention and language; RSST to executive function and attention; and lingual and oral motor function to all cognitive domains. The results suggest that the specific cognitive functional domains affected by oral function may vary.

Academic Significance and Societal Importance of the Research Achievements

本研究の結果、口腔機能によって、関わる高次脳機能が異なることが示唆された。この結果は、口腔因子がどの認知症に関連するかを知る手掛かりになり、医療関係者のみならず、日本国民へと広く影響を及ぼすことができると考えられる。

Report

(4 results)
  • 2022 Annual Research Report   Final Research Report ( PDF )
  • 2021 Research-status Report
  • 2020 Research-status Report
  • Research Products

    (5 results)

All 2023 2021 2020

All Journal Article (2 results) (of which Peer Reviewed: 2 results,  Open Access: 1 results) Presentation (3 results) (of which Int'l Joint Research: 1 results)

  • [Journal Article] Relationship between occlusal force and psychological frailty in Japanese community‐dwelling older adults: The Septuagenarians, Octogenarians, Nonagenarians Investigation with Centenarians study2023

    • Author(s)
      Akema Suzuna、Mameno Tomoaki、Nakagawa Takeshi、Inagaki Hiroki、Fukutake Motoyoshi、Hatta Kodai、Murotani Yuki、Tsujioka Yoshitaka、Hagino Hiromasa、Higashi Kotaro、Takahashi Toshihito、Wada Masahiro、Maeda Yoshinobu、Gondo Yasuyuki、Kamide Kei、Kabayama Mai、Ishizaki Tatsuro、Masui Yukie、Ogata Soshiro、Ikebe Kazunori
    • Journal Title

      Journal of the American Geriatrics Society

      Volume: - Issue: 6 Pages: 1819-1828

    • DOI

      10.1111/jgs.18239

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Decline of oral functions in old‐old adults and their relationship with age and sex: The SONIC study2021

    • Author(s)
      Hatta Kodai、Murotani Yuki、Takahashi Toshihito、Gondo Yasuyuki、Kamide Kei、Masui Yukie、Ishizaki Tatsuro、Ogata Soshiro、Matsuda Ken‐ichi、Mihara Yusuke、Fukutake Motoyoshi、Nishimura Yuichi、Hagino Hiromasa、Higashi Kotaro、Maeda Yoshinobu、Ikebe Kazunori
    • Journal Title

      Journal of the American Geriatrics Society

      Volume: 70 Issue: 2 Pages: 541-548

    • DOI

      10.1111/jgs.17535

    • Related Report
      2021 Research-status Report
    • Peer Reviewed / Open Access
  • [Presentation] 地域在住高齢者における認知的・社会的フレイルと口腔機能との関連の検討2021

    • Author(s)
      福武元良、八田昂大、高橋利士、三原佑介、室谷有紀、萩野弘将、東孝太郎、明間すずな、榎木香織、松田謙一、前田芳信、池邉一典
    • Organizer
      日本サルコペニアフレイル学会
    • Related Report
      2021 Research-status Report
  • [Presentation] Examination about simplification of diagnosis by selecting inspection items for oral hypofunction2021

    • Author(s)
      Hatta K
    • Organizer
      2nd JGS & TAGD Summit
    • Related Report
      2020 Research-status Report
    • Int'l Joint Research
  • [Presentation] 口腔機能低下症の検査項目数の選択による診断の簡易化についての検討2020

    • Author(s)
      八田 昂大,三原 佑介,村上 和裕,福武 元良,佐藤 仁美,萩野 弘将,室谷 有紀,高橋 利士,松田 謙一,池邉 一典
    • Organizer
      日本老年歯科医学会 第31回学術大会
    • Related Report
      2020 Research-status Report

URL: 

Published: 2020-04-28   Modified: 2024-01-30  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi