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Dietary factors influencing the associations between fluctuations in the 24-hour pattern of sleep-wake cycle and health status

Research Project

Project/Area Number 20K19720
Research Category

Grant-in-Aid for Early-Career Scientists

Allocation TypeMulti-year Fund
Review Section Basic Section 59040:Nutrition science and health science-related
Research InstitutionToyo University

Principal Investigator

Yoshizaki Takahiro  東洋大学, 食環境科学部, 准教授 (50732830)

Project Period (FY) 2020-04-01 – 2024-03-31
Project Status Completed (Fiscal Year 2023)
Budget Amount *help
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2023: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2022: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Fiscal Year 2021: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2020: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Keywords睡眠-覚醒リズムの日間類似性 / 食事の質 / 食事のタイミング / アクチグラフ / 休息活動リズム / 不規則な生活 / 食事 / 栄養 / 心身の健康 / 睡眠の質 / 時間栄養学 / 睡眠覚醒リズム / 血糖変動 / 日々の安定性 / 睡眠-覚醒リズム
Outline of Research at the Start

本研究は睡眠-覚醒リズムの変動による体内時計との時間的乖離が健康指標に及ぼす影響を把握し,脆弱性に関わる(その影響を緩和/悪化させる効果修飾を持つ)食生活要因をライフステージ別に探索する.具体的には,①観察的実験で急速な睡眠-覚醒リズムの生理学指標の定量化と食生活要因,健康指標との関連解析,②若年者と高齢者を対象とした追跡研究で,急速な睡眠-覚醒リズムの変動の健康影響に対して効果修飾を持つ食生活要因を示す.将来的に,本研究成果は日々の不可避なストレッサーへの対策として応用できる可能性があり,食生活を整える意義に対し,科学的根拠としての付加価値の創造が期待される.

Outline of Final Research Achievements

Our study focused on the discrepancy between the sleep-wake cycle and the internal clocks, which is caused by irregular lifestyles and social time constraints. The objective was to investigate the lifestyle-related characteristics of healthy young individuals with lower interdaily stability (IS) of their sleep-wake cycle. Additionally, the study aimed to elucidate the associations between IS, mental and physical health, and to explore dietary factors that could influence these associations. As a result, the lifestyle-related characteristics among those with lower IS of the 24-hour patterns of sleep-wake cycles and the associations with mental and physical health were clarified. Furthermore, it was suggested that the associations between lower IS of the 24-hour patterns of sleep-wake cycles and poor subjective health or lower sleep quality might be partially modified by daily fluctuations in meal timing and the ratios of energy intake at breakfast, lunch, and dinner.

Academic Significance and Societal Importance of the Research Achievements

日常生活の不規則さは様々な社会的環境要因による時間的制約が背景となっており、個人の努力や集団レベルの健康施策による早期改善は容易ではない。本研究で得られた睡眠-覚醒リズムの24時間パターンの日間類似性が低いことによる健康影響は、生活リズムの乱れといった類似の指標を曝露とした先行研究の結果と一致している。また、本研究ではそれらの関連の一部に影響し得る食習慣の特徴を明らかにした。そのため、本研究で得られた知見は、不規則な生活にならざるを得ない集団における健康維持増進に向け、食習慣に注目した新たな対応策として有用な基礎資料となり得ると考えられる。

Report

(5 results)
  • 2023 Annual Research Report   Final Research Report ( PDF )
  • 2022 Research-status Report
  • 2021 Research-status Report
  • 2020 Research-status Report
  • Research Products

    (18 results)

All 2024 2023 2022 2021 2020

All Journal Article (12 results) (of which Peer Reviewed: 11 results,  Open Access: 8 results) Presentation (2 results) (of which Int'l Joint Research: 1 results,  Invited: 1 results) Book (4 results)

  • [Journal Article] Association of breakfast skipping with habitual dietary intake and BMI in female rotating shift workers2023

    • Author(s)
      Yoshizaki Takahiro、Komatsu Taiki、Tada Yuki、Togo Fumiharu
    • Journal Title

      Public Health Nutrition

      Volume: 26 Issue: 8 Pages: 1634-1643

    • DOI

      10.1017/s1368980023000794

    • Related Report
      2023 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Investigation of supplement use and knowledge among Japanese elite athletes for the Tokyo 2020 Olympic/Paralympic games and the Beijing 2022 winter Olympic/Paralympic games2023

    • Author(s)
      Myoenzono Kanae、Yasuda Jun、Takai Eri、Shinagawa Akiho、Kaneko Noburo、Yoshizaki Takahiro、Namma-Motonaga Keiko、Yoshino Masae、Kondo Emi、Nakajima Kohei、Hangai Mika、Kamahara Kazuyuki、Kamihigashi Etsuko、Kusano Shusuke、Kamei Akiko
    • Journal Title

      Frontiers in Sports and Active Living

      Volume: 5 Pages: 1258542-1258542

    • DOI

      10.3389/fspor.2023.1258542

    • Related Report
      2023 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Association of breakfast skipping with habitual dietary intake and body mass index in female rotating shift workers2023

    • Author(s)
      Yoshizaki Takahiro、Komatsu Taiki、Tada Yuki、Togo Fumiharu
    • Journal Title

      Public Health Nutrition

      Volume: -

    • Related Report
      2022 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Association between irregular daily routine and risk of incident stroke and coronary heart disease in a large Japanese population2022

    • Author(s)
      Yoshizaki Takahiro、Ishihara Junko、Kotemori Ayaka、Kokubo Yoshihiro、Saito Isao、Yatsuya Hiroshi、Yamagishi Kazumasa、Sawada Norie、Iwasaki Motoki、Iso Hiroyasu、Tsugane Shoichiro、The JPHC Study Group
    • Journal Title

      Scientific Reports

      Volume: 12 Issue: 1 Pages: 15750-15750

    • DOI

      10.1038/s41598-022-20019-8

    • Related Report
      2022 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Interactive effects of job stressor and chronotype on depressive symptoms in day shift and rotating shift workers2022

    • Author(s)
      Togo Fumiharu、Yoshizaki Takahiro、Komatsu Taiki
    • Journal Title

      Journal of Affective Disorders Reports

      Volume: 9 Pages: 100352-100352

    • DOI

      10.1016/j.jadr.2022.100352

    • Related Report
      2022 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] 栄養疫学における観察研究へのSTROBE声明の拡張版(STROBE-nut): 紹介と解説2022

    • Author(s)
      上岡 洋晴、吉﨑 貴大、足立 里穂、大野 富美、杉本 南、髙岡 友哉、津谷 喜一郎、佐々木 敏
    • Journal Title

      薬理と治療

      Volume: 50 Pages: 1749-1764

    • Related Report
      2022 Research-status Report
  • [Journal Article] Nutrient Profiles of Dishes Consumed by the Adequate and High-Salt Groups in the 2014-2018 National Health and Nutrition Survey, Japan2021

    • Author(s)
      Takimoto H, Okada E, Takebayashi J, Tada Y, Yoshizaki T, Yokoyama Y, Ishimi Y
    • Journal Title

      Nutrients

      Volume: 28 Issue: 8 Pages: 2591-2591

    • DOI

      10.3390/nu13082591

    • Related Report
      2021 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Objectively measured chronotype and social jetlag are associated with habitual dietary intake in undergraduate students2021

    • Author(s)
      Yoshizaki T, Togo F.
    • Journal Title

      Nutrition Research

      Volume: 90 Pages: 36-45

    • DOI

      10.1016/j.nutres.2021.04.003

    • Related Report
      2021 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Dietary variety is associated with sleep efficiency in urban-dwelling older adults: A longitudinal study2021

    • Author(s)
      Yamamoto Kaori、Motokawa Keiko、Yoshizaki Takahiro、Yano Tomohiro、Hirano Hirohiko、Ohara Yuki、Shirobe Maki、Hayakawa Misato、Inagaki Hiroki、Awata Shuichi、Shinkai Shoji、Watanabe Yutaka
    • Journal Title

      Clinical Nutrition ESPEN

      Volume: 41 Pages: 391-397

    • DOI

      10.1016/j.clnesp.2020.10.013

    • Related Report
      2020 Research-status Report
    • Peer Reviewed
  • [Journal Article] Breakfast before resistance exercise lessens urinary markers of muscle protein breakdown in young men: A crossover trial2021

    • Author(s)
      Jun Yasuda, Tatsunosuke Gomi, Ayaka Kotemori, Yuri Yokoyama, Takahiro Yoshizaki, Azumi Hida, Yuki Tada, Yoichi Katsumata, Yukari Kawano
    • Journal Title

      Nutrition

      Volume: 83 Pages: 1-7

    • DOI

      10.1016/j.nut.2020.111088

    • Related Report
      2020 Research-status Report
    • Peer Reviewed
  • [Journal Article] Objectively measured chronotype and social jetlag are associated with habitual dietary intake in undergraduate students2021

    • Author(s)
      Yoshizaki Takahiro、Togo Fumiharu
    • Journal Title

      Nutrition Research

      Volume: -

    • Related Report
      2020 Research-status Report
    • Peer Reviewed
  • [Journal Article] Association between vegetable consumption and calf venous compliance in healthy young adults2020

    • Author(s)
      Oue Anna、Iimura Yasuhiro、Maeda Kotose、Yoshizaki Takahiro
    • Journal Title

      Journal of Physiological Anthropology

      Volume: 39 Issue: 1

    • DOI

      10.1186/s40101-020-00231-z

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access
  • [Presentation] Association between robustness of 24-hour pattern of sleep/wake, energy intake, and interstitial glucose level over seven days among young adults2022

    • Author(s)
      Yoshizaki Takahiro、Konishi Kana、Togo Fumiharu
    • Organizer
      22nd IUNS-ICN International Congress of Nutrition
    • Related Report
      2022 Research-status Report
    • Int'l Joint Research
  • [Presentation] 日本版栄養プロファイルモデル試案の作成に向けた基礎的研究2021

    • Author(s)
      吉﨑 貴大,横山 友里,多田 由紀,岡田 恵美子, 竹林 純,瀧本 秀美,石見 佳子
    • Organizer
      第68回日本栄養改善学会学術総会 リレー特別講演
    • Related Report
      2021 Research-status Report
    • Invited
  • [Book] 公衆栄養学・栄養疫学実習2024

    • Author(s)
      石原淳子 髙地リベカ 鬼頭久美子 木村安美 小手森綾香 後藤温 多田由紀 遠又靖丈 丸谷幸子 丸山広達 村井詩子 吉﨑貴大
    • Total Pages
      168
    • Publisher
      建帛社
    • ISBN
      9784767907529
    • Related Report
      2023 Annual Research Report
  • [Book] 時間栄養学2020

    • Author(s)
      柴田 重信
    • Total Pages
      256
    • Publisher
      化学同人
    • ISBN
      9784759820362
    • Related Report
      2020 Research-status Report
  • [Book] アグリバイオ, vol.4 No.8 p28-322020

    • Author(s)
      吉﨑 貴大,東郷 史治
    • Total Pages
      102
    • Publisher
      北隆館
    • Related Report
      2020 Research-status Report
  • [Book] 臨床栄養第136巻第3号 p327-3332020

    • Author(s)
      吉﨑 貴大,東郷 史治
    • Publisher
      医歯薬出版株式会社
    • Related Report
      2020 Research-status Report

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Published: 2020-04-28   Modified: 2025-01-30  

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