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Core Technologies in Analyzing and Estimating the Influences of Exogenous Factors of Heart Health

Research Project

Project/Area Number 20K19923
Research Category

Grant-in-Aid for Early-Career Scientists

Allocation TypeMulti-year Fund
Review Section Basic Section 62010:Life, health and medical informatics-related
Research InstitutionNagoya City University (2023)
Nara Institute of Science and Technology (2020-2022)

Principal Investigator

Huang Ming  名古屋市立大学, データサイエンス学部, 准教授 (50728300)

Project Period (FY) 2020-04-01 – 2024-03-31
Project Status Completed (Fiscal Year 2023)
Budget Amount *help
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2022: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2021: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2020: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Keywords睡眠 / 運動 / 個人向け健康機器 / 食生活 / AI技術 / 健康情報 / 機械学習 / 深層学習 / 転移学習 / 容積光電脈波 / 循環器 / 複雑活動認識 / 睡眠健康 / カフレス血圧推定 / マシンラーニング / 人間活動認識 / 睡眠分類 / 不整脈予測 / 個人健康システム / 心臓健康 / 食
Outline of Research at the Start

心臓の健康は、遺伝子型の因子以外、睡眠・運動・食習慣などの後天性因子に大きく影響される。ICT、IoT技術の発展に伴い、ウェアラブル・個人ヘルス機器による生体情報の収集とデータの活用はできているので、個人心臓健康状態の把握、心疾患発症の抑制、健康状態を取り戻すことは可能になっている。そこで、本研究は、簡易のウェアラブル・非接触装置を用いた後天性因子の定量化手段の研究開発からはじめ、データサイエンスの観点から個人差を考慮した後天性因子の心臓健康影響モデルも構築することによって、心臓健康の維持・改善を目的に、積極的に生活・活動変容を促す。

Outline of Final Research Achievements

This study aimed to elucidate the impact of three lifestyle factors: sleep, exercise, and diet (collectively referred to as FES factors) on cardiac health. We developed a foundational technology that allows for the quantitative measurement of these factors without affecting quality of life, using accumulated data to estimate the correlation between cardiac health and FES factors. Specifically, we focused on two main areas:
We developed an estimation method for sleep states based on multimodal physiological signals, establishing signal processing and AI technologies to monitor cardiac states during sleep.
Using multimodal biosignals collected from wearable devices, we developed AI technology to automatically recognize daily activities, establishing signal processing and AI technologies that enable the monitoring of cardiac health during active periods.

Academic Significance and Societal Importance of the Research Achievements

心臓の状態は遺伝的要因のみならず、食事、運動、睡眠といった後天的な生活習慣因子にも依存する。これらのFES因子を積極的に改善することで、未病の状態から健康を取り戻す可能性が期待される。したがって、健康から未病を経て病気の発症に至るまでの健康状態を把握するために、本研究はデジタルヘルスを通じてウェアラブルデバイスや個人向け健康機器を使用し、生体情報を収集及び活用する手法に焦点を当たった。日常生活の中でFES因子を定量的に記録するや昼夜問わず心臓の健康状態を監視する技術を開発した。この技術は、生活習慣因子を調整する運動療法や食事療法の個別化及び効果の向上に寄与することが期待される。

Report

(5 results)
  • 2023 Annual Research Report   Final Research Report ( PDF )
  • 2022 Research-status Report
  • 2021 Research-status Report
  • 2020 Research-status Report
  • Research Products

    (29 results)

All 2023 2022 2021 2020

All Journal Article (14 results) (of which Int'l Joint Research: 7 results,  Peer Reviewed: 12 results,  Open Access: 10 results) Presentation (14 results) (of which Int'l Joint Research: 12 results,  Invited: 3 results) Book (1 results)

  • [Journal Article] Estimating Blood Pressure during Exercise with a Cuffless Sphygmomanometer2023

    • Author(s)
      Hayashi Kenta、Maeda Yuka、Yoshimura Takumi、Huang Ming、Tamura Toshiyo
    • Journal Title

      Sensors

      Volume: 23 Issue: 17 Pages: 7399-7399

    • DOI

      10.3390/s23177399

    • Related Report
      2023 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] On QSAR-based cardiotoxicity modeling with the expressiveness-enhanced graph learning model and dual-threshold scheme2023

    • Author(s)
      Wang Huijia、Zhu Guangxian、Izu Leighton T.、Chen-Izu Ye、Ono Naoaki、Altaf-Ul-Amin MD、Kanaya Shigehiko、Huang Ming
    • Journal Title

      Frontiers in Physiology

      Volume: 14

    • DOI

      10.3389/fphys.2023.1156286

    • Related Report
      2022 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Automated Sleep Staging via Parallel Frequency-Cut Attention2023

    • Author(s)
      Chen Zheng、Yang Ziwei、Zhu Lingwei、Chen Wei、Tamura Toshiyo、Ono Naoaki、Altaf-Ul-Amin Md、Kanaya Shigehiko、Huang Ming
    • Journal Title

      IEEE Transactions on Neural Systems and Rehabilitation Engineering

      Volume: 31 Pages: 1974-1985

    • DOI

      10.1109/tnsre.2023.3243589

    • Related Report
      2022 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] A training pipeline of an arrhythmia classifier for atrial fibrillation detection using Photoplethysmography signal2023

    • Author(s)
      Kudo Sota、Chen Zheng、Zhou Xue、Izu Leighton T.、Chen-Izu Ye、Zhu Xin、Tamura Toshiyo、Kanaya Shigehiko、Huang Ming
    • Journal Title

      Frontiers in Physiology

      Volume: 14 Pages: 1084837-1084837

    • DOI

      10.3389/fphys.2023.1084837

    • Related Report
      2022 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Sleep Staging Framework with Physiologically Harmonized Sub-Networks2023

    • Author(s)
      Chen Zheng、Yang Ziwei、Wang Dong、Zhu Xin、Ono Naoaki、Altaf-Ul-Amin M.D.、Kanaya Shigehiko、Huang Ming
    • Journal Title

      Methods

      Volume: 209 Pages: 18-28

    • DOI

      10.1016/j.ymeth.2022.11.003

    • Related Report
      2022 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] An Advanced Internet of Things System for Heatstroke Prevention with a Noninvasive Dual-Heat-Flux Thermometer2022

    • Author(s)
      Tamura Toshiyo、Huang Ming、Yoshimura Takumi、Umezu Shinjiro、Ogata Toru
    • Journal Title

      Sensors

      Volume: 22 Issue: 24 Pages: 9985-9985

    • DOI

      10.3390/s22249985

    • Related Report
      2022 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Sleep postures monitoring based on capacitively coupled electrodes and deep recurrent neural networks2022

    • Author(s)
      Peng Shun、Li Yang、Cui Rui、Xu Ke、Wu Yonglin、Huang Ming、Dai Chenyun、Tamur Toshiyo、Mukhopadhyay Subhas、Chen Chen、Chen Wei
    • Journal Title

      BioMedical Engineering OnLine

      Volume: 21 Issue: 1

    • DOI

      10.1186/s12938-022-01031-5

    • Related Report
      2022 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Enhancement on Model Interpretability and Sleep Stage Scoring Performance with A Novel Pipeline Based on Deep Neural Network2022

    • Author(s)
      Zheng Chen, Ziwei Yang, Ming Huang, Toshiyo Tamura, Naoaki Ono, MD Altaf-Ul-Amin, Shigehiko Kanaya
    • Journal Title

      arXiv preprint

      Volume: 22 Pages: 1-14

    • Related Report
      2021 Research-status Report
  • [Journal Article] Cancer Subtyping via Embedded Unsupervised Learning on Transcriptomics Data2022

    • Author(s)
      Ziwei Yang, Lingwei Zhu, Zheng Chen, Ming Huang, Naoaki Ono, MD Altaf-Ul-Amin, Shigehiko Kanaya
    • Journal Title

      arXiv preprint

      Volume: 22 Pages: 1-4

    • Related Report
      2021 Research-status Report
  • [Journal Article] Recent trends in computational biomedical research2021

    • Author(s)
      Md Altaf-Ul-Amin, Shigehiko Kanaya, Naoaki Ono, Ming Huang
    • Journal Title

      Life

      Volume: 12 Issue: 1 Pages: 26-26

    • DOI

      10.3390/life12010027

    • Related Report
      2021 Research-status Report
    • Peer Reviewed
  • [Journal Article] Discussion of Cuffless Blood Pressure Prediction Using Plethysmograph Based on a Longitudinal Experiment: Is the Individual Model Necessary?2021

    • Author(s)
      Kido Koshiro、Chen Zheng、Huang Ming、Tamura Toshiyo、Chen Wei、Ono Naoaki、Takeuchi Masachika、Altaf-Ul-Amin Md.、Kanaya Shigehiko
    • Journal Title

      Life

      Volume: 12 Issue: 1 Pages: 11-11

    • DOI

      10.3390/life12010011

    • Related Report
      2021 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] A Realtime Portable IoT System for Telework Tracking2021

    • Author(s)
      Yongxin Zhang, Zheng Chen, Haoyu Tian, Koshiro Kido, Naoaki Ono, Wei Chen, Toshiyo Tamura, MD Altaf-Ul-Amin, Shigehiko Kanaya and Ming Huang
    • Journal Title

      Frontiers in Digital Health

      Volume: - Pages: 1-17

    • DOI

      10.3389/fdgth.2021.643042

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] The Feasibility of Predicting Impending Malignant Ventricular Arrhythmias by Using Nonlinear Features of Short Heartbeat Intervals2021

    • Author(s)
      Zheng Chen, Naoaki Ono, Wei Chen, Toshiyo Tamura, MD Altaf-Ul-Amin, Shigehiko Kanaya, Ming Huang
    • Journal Title

      Computer Methods and Programs in Biomedicine

      Volume: - Pages: 1-14

    • DOI

      10.1016/j.cmpb.2021.106102

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Development of a biomarker database toward performing disease classification and finding disease interrelations2021

    • Author(s)
      Hossain, Shaikh Farhad, Ming Huang, Naoaki Ono, Aki Morita, Shigehiko Kanaya, and Md Altaf-Ul-Amin
    • Journal Title

      Database

      Volume: 2021 Pages: 1-17

    • DOI

      10.1093/database/baab011

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Presentation] Estimating blood pressure during exercise with a cuffless sphygmomanometer2023

    • Author(s)
      Ming Huang
    • Organizer
      IEEE EMBC2023
    • Related Report
      2023 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 睡眠状態における心脳モニタリング技術2023

    • Author(s)
      黄銘
    • Organizer
      中国生体医用工学学科発展大会会議
    • Related Report
      2023 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Straightforward Clustering and Identification of Morphological-Level Pancreatic Carcinoma2022

    • Author(s)
      Guangxian Zhu, Huijia Wang, Ming Huang, Md Amin, Naoaki Ono, Shigehiko Kanaya
    • Organizer
      2022 IEEE 11th Global Conference on Consumer Electronics
    • Related Report
      2022 Research-status Report
    • Int'l Joint Research
  • [Presentation] A Stochastic Coding Method of EEG Signals for Sleep Stage Classification2022

    • Author(s)
      Guangxian Zhu, Huijia Wang, Yirong Kan, Zheng Chen, Ming Huang, MD Amin, Naoaki Ono, Shigehiko Kanaya, Renyuan Zhang
    • Organizer
      2022 IEEE 35th International System-on-Chip Conference
    • Related Report
      2022 Research-status Report
    • Int'l Joint Research
  • [Presentation] AIoT technologies for healthcare in Society 5.02022

    • Author(s)
      Ming Huang
    • Organizer
      17th International Symposium on Biomedical Engineering, Toin University of Yokohama
    • Related Report
      2022 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] Deep Learning-Based Sleep Staging with Acceleration and Heart Rate Data of a Consumer Wearable Device2022

    • Author(s)
      Sota Kudo, Zheng Chen, Naoaki Ono, MD Altaf-Ul-Amin, Shigehiko Kanaya, Ming Huang
    • Organizer
      2022 IEEE 4th Global Conference on Life Sciences and Technologies
    • Related Report
      2021 Research-status Report
    • Int'l Joint Research
  • [Presentation] Reconciling of the distances in physical space and latent feature space for complex activity modeling2022

    • Author(s)
      Yongxin Zhang, Naoaki Ono, MD Altaf-Ul-Amin, Shigehiko Kanaya, Ming Huang
    • Organizer
      2022 IEEE 4th Global Conference on Life Sciences and Technologies
    • Related Report
      2021 Research-status Report
    • Int'l Joint Research
  • [Presentation] Guang Shi, Zheng Chen, Ming Huang, Renyuan Zhang, Naoaki Ono, Md Altaf-UI-Amin, Shigehiko Kanaya2022

    • Author(s)
      Algorithm Cocktail Approach for Predicting Body Constitution and Bias Recovery
    • Organizer
      2022 IEEE 4th Global Conference on Life Sciences and Technologies
    • Related Report
      2021 Research-status Report
    • Int'l Joint Research
  • [Presentation] An End-to-End Sleep Staging Simulator Based on Mixed Deep Neural Networks2021

    • Author(s)
      Zheng Chen, Ziwei Yang, Dong Wang, Ming Huang, Naoaki Ono, Md Altaf-Ul-Amin, Shigehiko Kanaya
    • Organizer
      2021 IEEE International Conference on Bioinformatics and Biomedicine
    • Related Report
      2021 Research-status Report
    • Int'l Joint Research
  • [Presentation] Exploring Feasibility of Truth-Involved Automatic Sleep Staging Combined with Transformer2021

    • Author(s)
      Ziwei Yang, Dong Wang, Zheng Chen, Ming Huang, Naoaki Ono, Md Altaf-Ul-Amin, Shigehiko Kanaya
    • Organizer
      2021 IEEE International Conference on Bioinformatics and Biomedicine
    • Related Report
      2021 Research-status Report
    • Int'l Joint Research
  • [Presentation] An Integrated Multi-Omics Approach for AMR Phenotype Prediction of Gut Microbiota2021

    • Author(s)
      Pei Gao, Zheng Chen, Dong Wang, Ming Huang, Naoaki Ono, Md Altaf-Ul-Amin, Shigehiko Kanaya
    • Organizer
      2021 IEEE International Conference on Bioinformatics and Biomedicine
    • Related Report
      2021 Research-status Report
    • Int'l Joint Research
  • [Presentation] Feasibility Analysis of Symbolic Representation for Single-Channel EEG-Based Sleep Stages2021

    • Author(s)
      Zheng Chen, Pei Gao, Ming Huang, Naoaki Ono, MD Altaf-Ul-Amin, Shigehiko Kanaya
    • Organizer
      2021 43rd Annual International Conference of the IEEE Engineering in Medicine & Biology Society
    • Related Report
      2021 Research-status Report
    • Int'l Joint Research
  • [Presentation] Prediction of Body Constitutions through Life-Style for Health Guidance2021

    • Author(s)
      Guang Shi, Zhen Chen, Shigehiko Kanaya, Md Altaf-UI-Amin, Naoaki Ono, Ming Huang
    • Organizer
      2021 IEEE 3rd Global Conference on Life Sciences and Technologies
    • Related Report
      2020 Research-status Report
  • [Presentation] iVAE: A New Deep Learning Structure for EEG Signal Characterization and Reconstruction2020

    • Author(s)
      Zheng Chen, Naoaki Ono, MD Altaf-Ul-Amin, Shigehiko Kanaya, Ming Huang
    • Organizer
      2020 IEEE International Conference on Bioinformatics and Biomedicine
    • Related Report
      2020 Research-status Report
  • [Book] Recent trends in computational biomedical research2022

    • Author(s)
      Md Altaf-Ul-Amin, Shigehiko Kanaya, Naoaki Ono, Ming Huang
    • Total Pages
      119
    • Publisher
      MDPI
    • ISBN
      9783036532301
    • Related Report
      2021 Research-status Report

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Published: 2020-04-28   Modified: 2025-01-30  

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