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Understanding the genetic mechanism of adaptive evolution and parallel evolution in East African cichlids

Research Project

Project/Area Number 20KK0167
Research Category

Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))

Allocation TypeMulti-year Fund
Review Section Medium-sized Section 45:Biology at organismal to population levels and anthropology, and related fields
Research InstitutionTokyo Institute of Technology

Principal Investigator

Nikaido Masato  東京工業大学, 生命理工学院, 准教授 (70432010)

Co-Investigator(Kenkyū-buntansha) 長澤 竜樹  東京工業大学, 生命理工学院, 助教 (60782828)
高橋 鉄美  兵庫県立大学, 自然・環境科学研究所, 教授 (70432359)
Project Period (FY) 2020-10-27 – 2024-03-31
Project Status Completed (Fiscal Year 2023)
Budget Amount *help
¥16,770,000 (Direct Cost: ¥12,900,000、Indirect Cost: ¥3,870,000)
Fiscal Year 2023: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2022: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2021: ¥6,370,000 (Direct Cost: ¥4,900,000、Indirect Cost: ¥1,470,000)
Fiscal Year 2020: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Keywordsシクリッド / 平行進化 / 適応放散 / 祖先多型 / 東アフリカ産シクリッド / ゲノム比較 / フェロモン / 適応進化 / 全ゲノム比較 / V1R / 祖先集団多型 / フェロモン受容体 / 全ゲノム比較解析
Outline of Research at the Start

本研究は適応放散や平行進化の典型例として知られているシクリッドに着目し、その適応放散・平行進化が祖先多型に由来するものか否かを検証する。そのため、タンザニアにおける野外調査、SGV由来アリルをもつV1R2を介したシクリッドの種分化の検証、SGV由来アリルをもつMAGP4遺伝子の発現低下と唇の肥大化の検証の3つのテーマを立てて、研究実施を進める。

Outline of Final Research Achievements

In this research plan, we comprehensively explored candidate genes involved in adaptation and speciation based on a whole-genome comparative analysis of Lake Victoria cichlids (three species, 6 individuals/species). Phylogenetic analysis of the candidate genes for the three major East African lake cichlids, revealed that the origin of the alleles of these 99 candidate genes were older than the common ancestor of Lake Victoria, indicating that they were derived from ancestral polymorphisms. This suggests that ancestral polymorphisms retained in the ancestral population have contributed to the genomic basis of the adaptive radiation and parallel evolution of cichlids.

Academic Significance and Societal Importance of the Research Achievements

種分化やそれが連続して起こる適応放散、そしてその一環として起きた平行進化のメカニズムについては、現代進化学でも完全なる理解に至っていない命題といえる。本研究では適応放散や平行進化の典型例として知られる東アフリカ産シクリッドに着目して、この問題に取り組んだ。その結果、東アフリカ産シクリッドのゲノム中には、多くの祖先多型が存在していることが分かり、これが適応放散や平行進化の遺伝的基盤となった可能性を示唆することに成功し、この学術的意義は大きいと考えられる。

Report

(5 results)
  • 2023 Annual Research Report   Final Research Report ( PDF )
  • 2022 Research-status Report
  • 2021 Research-status Report
  • 2020 Research-status Report
  • Research Products

    (75 results)

All 2024 2023 2022 2021 Other

All Int'l Joint Research (3 results) Journal Article (13 results) (of which Int'l Joint Research: 2 results,  Peer Reviewed: 13 results,  Open Access: 10 results) Presentation (54 results) (of which Int'l Joint Research: 6 results,  Invited: 7 results) Book (2 results) Remarks (3 results)

  • [Int'l Joint Research] タンザニア水産研究所(タンザニア)

    • Related Report
      2023 Annual Research Report
  • [Int'l Joint Research] メリーランド大学(米国)

    • Related Report
      2023 Annual Research Report
  • [Int'l Joint Research] ベルン大学(スイス)

    • Related Report
      2023 Annual Research Report
  • [Journal Article] Localized Expression of Olfactory Receptor Genes in the Olfactory Organ of Common Minke Whales2024

    • Author(s)
      Hirose Ayumi、Nakamura Gen、Nikaido Masato、Fujise Yoshihiro、Kato Hidehiro、Kishida Takushi
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 25 Issue: 7 Pages: 3855-3855

    • DOI

      10.3390/ijms25073855

    • Related Report
      2023 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Unveiling the expansion of keratin genes in lungfishes: a possible link to terrestrial adaptation2023

    • Author(s)
      Kimura Yuki、Nikaido Masato
    • Journal Title

      Genes & Genetic Systems

      Volume: 98 Issue: 5 Pages: 249-257

    • DOI

      10.1266/ggs.23-00188

    • ISSN
      1341-7568, 1880-5779
    • Year and Date
      2023-10-01
    • Related Report
      2023 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Ancient standing genetic variation facilitated the adaptive radiation of Lake Victoria cichlids2023

    • Author(s)
      Nakamura Haruna、Aibara Mitsuto、Nikaido Masato
    • Journal Title

      Genes & Genetic Systems

      Volume: 98 Issue: 2 Pages: 93-99

    • DOI

      10.1266/ggs.23-00024

    • ISSN
      1341-7568, 1880-5779
    • Year and Date
      2023-04-01
    • Related Report
      2023 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] In situ hybridization analysis of odorant receptor expression in the olfactory organ of the pig-nosed turtle Carettochelys insculpta2023

    • Author(s)
      Nakamuta Shoko、Itoh Miho、Mori Masanori、Kurita Masanori、Zhang Zicong、Nikaido Masato、Miyazaki Masao、Yokoyama Takuya、Yamamoto Yoshio、Nakamuta Nobuaki
    • Journal Title

      Tissue and Cell

      Volume: 85 Pages: 102255-102255

    • DOI

      10.1016/j.tice.2023.102255

    • Related Report
      2023 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Expression of type 1 vomeronasal receptors in the olfactory organ of the African lungfish, Protopterus dolloi2023

    • Author(s)
      Nakamuta Shoko、Sakuma Atsuhiro、Nikaido Masato、Kato Hideaki、Miyazaki Masao、Yamamoto Yoshio、Nakamuta Nobuaki
    • Journal Title

      Acta Histochemica

      Volume: 125 Issue: 7 Pages: 152078-152078

    • DOI

      10.1016/j.acthis.2023.152078

    • Related Report
      2023 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Type 1 vomeronasal receptor expression in juvenile and adult lungfish olfactory organ2023

    • Author(s)
      Nakamuta Shoko、Yamamoto Yoshio、Miyazaki Masao、Sakuma Atsuhiro、Nikaido Masato、Nakamuta Nobuaki
    • Journal Title

      Zoological Letters

      Volume: 9 Issue: 1 Pages: 6-6

    • DOI

      10.1186/s40851-023-00202-z

    • Related Report
      2023 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Plastic loss of motile cilia in the gills of Polypterus in response to high CO2 or terrestrial environments2023

    • Author(s)
      Kimura Yuki、Nakamuta Nobuaki、Nikaido Masato
    • Journal Title

      Ecology and Evolution

      Volume: 13 Issue: 4

    • DOI

      10.1002/ece3.9964

    • Related Report
      2023 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] c-fos expression in the olfactory epithelium of the East African cichlid (Haplochromis chilotes) in response to odorant exposure2022

    • Author(s)
      Kawamura Riki、Nikaido Masato
    • Journal Title

      Journal of Experimental Biology

      Volume: 225 Issue: 20

    • DOI

      10.1242/jeb.244737

    • Related Report
      2022 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] New Sex Chromosomes in Lake Victoria Cichlid Fishes (Cichlidae: Haplochromini)2022

    • Author(s)
      Kocher Thomas D.、Behrens Kristen A.、Conte Matthew A.、Aibara Mitsuto、Mrosso Hillary D. J.、Green Elizabeth C. J.、Kidd Michael R.、Nikaido Masato、Koblmuller Stephan
    • Journal Title

      Genes

      Volume: 13 Issue: 5 Pages: 804-804

    • DOI

      10.3390/genes13050804

    • Related Report
      2022 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Data of RNA-seq transcriptomes in the brain associated with aggression in males of the fish Betta splendens2021

    • Author(s)
      Vu Trieu-Duc、Iwasaki Yuki、Oshima Kenshiro、Chiu Ming-Tzu、Nikaido Masato、Okada Norihiro
    • Journal Title

      Data in Brief

      Volume: 38 Pages: 107448-107448

    • DOI

      10.1016/j.dib.2021.107448

    • Related Report
      2021 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Conserved keratin gene clusters in ancient fish: An evolutionary seed for terrestrial adaptation2021

    • Author(s)
      Kimura Yuki、Nikaido Masato
    • Journal Title

      Genomics

      Volume: 113 Issue: 1 Pages: 1120-1128

    • DOI

      10.1016/j.ygeno.2020.11.008

    • Related Report
      2020 Research-status Report
    • Peer Reviewed
  • [Journal Article] Genomic Signatures for Species-Specific Adaptation in Lake Victoria Cichlids Derived from Large-Scale Standing Genetic Variation2021

    • Author(s)
      Nakamura Haruna、Aibara Mitsuto、Kajitani Rei、Mrosso Hillary D J、Mzighani Semvua I、Toyoda Atsushi、Itoh Takehiko、Okada Norihiro、Nikaido Masato
    • Journal Title

      Molecular Biology and Evolution

      Volume: in press Issue: 8 Pages: 3111-3125

    • DOI

      10.1093/molbev/msab084

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] A unique neurogenomic state emerges after aggressive confrontations in males of the fish Betta splendens2021

    • Author(s)
      Vu Trieu-Duc、Iwasaki Yuki、Oshima Kenshiro、Chiu Ming-Tzu、Nikaido Masato、Okada Norihiro
    • Journal Title

      Gene

      Volume: 784 Pages: 145601-145601

    • DOI

      10.1016/j.gene.2021.145601

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Presentation] ポリプテルスの鼻管における化学感覚の研究2024

    • Author(s)
      伊藤隆晃, 西浦賀乃子, 木村優希, 中牟田信明, 長澤竜樹, 二階堂雅人
    • Organizer
      日本動物学会関東支部第76回大会, 東京大学
    • Related Report
      2023 Annual Research Report
  • [Presentation] 哺乳類フェロモン受容体V1R の進化的起源2023

    • Author(s)
      二階堂雅人
    • Organizer
      第9回ケモビ研究会, 御殿場高原時之栖
    • Related Report
      2023 Annual Research Report
  • [Presentation] 魚類の全ゲノム倍化後のOMP 遺伝子発現パターンの進化的比較解析2023

    • Author(s)
      長澤竜樹,藤崎花美, 二階堂雅人
    • Organizer
      第9回ケモビ研究会, 御殿場高原時之栖
    • Related Report
      2023 Annual Research Report
  • [Presentation] シクリッドV1R 遺伝子の多様性と機能的関連2023

    • Author(s)
      滝隼輔, 二階堂雅人
    • Organizer
      第9回ケモビ研究会, 御殿場高原時之栖
    • Related Report
      2023 Annual Research Report
  • [Presentation] 魚類における化学受容体の異所的な分布2023

    • Author(s)
      西浦賀乃子,張子聡,長澤竜樹,二階堂雅人
    • Organizer
      日本味と匂学会第57回大会, 東京工業大学
    • Related Report
      2023 Annual Research Report
  • [Presentation] ヨザル属における鋤鼻機能退化の可能性に関する遺伝学的な検証2023

    • Author(s)
      小林愛実, 新宅勇太, 河村正二, 二階堂雅人
    • Organizer
      日本味と匂学会第57回大会, 東京工業大学
    • Related Report
      2023 Annual Research Report
  • [Presentation] 魚類の全ゲノム重複で倍化したOMP遺伝子の進化プロセスとその多様化2023

    • Author(s)
      長澤竜樹,藤崎花美, 二階堂雅人
    • Organizer
      日本味と匂学会第57回大会, 東京工業大学
    • Related Report
      2023 Annual Research Report
  • [Presentation] シクリッドにおけるV1R嗅覚受容体遺伝子の多様性創出メカニズムの解明2023

    • Author(s)
      滝隼輔,二階堂雅人
    • Organizer
      日本味と匂学会第57回大会, 東京工業大学
    • Related Report
      2023 Annual Research Report
  • [Presentation] 水陸両生魚・ポリプテルスの陸上環境における恒常性維持機構 (Homeostatic mechanism in the terrestrial environment of Polypterus)2023

    • Author(s)
      木村優希, 神田真司, 兵藤晋, 二階堂雅人
    • Organizer
      日本動物学会第94回大会, 山形大学
    • Related Report
      2023 Annual Research Report
  • [Presentation] Ectopic expression of chemoreceptor genes in fish2023

    • Author(s)
      Nishiura, K.,Zhang, Z.,Nagasawa, T.,Nikaido, M.
    • Organizer
      日本進化学会第25回大会, 琉球大学共通教育棟, 沖縄県市町村自治会館
    • Related Report
      2023 Annual Research Report
  • [Presentation] Functional differentiation of food-related olfactory receptor V2R in cichlid2023

    • Author(s)
      Kawamura, R.,Nikaido, M.
    • Organizer
      日本進化学会第25回大会, 琉球大学共通教育棟, 沖縄県市町村自治会館
    • Related Report
      2023 Annual Research Report
  • [Presentation] The Genomic Basis for Trophic Adaptation of East African Egg-Eating Cichlids2023

    • Author(s)
      Imamoto, M., Nakamura, H., Aibara, M., Nikaido, M.
    • Organizer
      日本進化学会第25回大会, 琉球大学共通教育棟, 沖縄県市町村自治会館
    • Related Report
      2023 Annual Research Report
  • [Presentation] Comparative Analysis of Hypertrophic Lips in East African Cichlid2023

    • Author(s)
      Machii, N.,Hatashima, R.,Aibara, M.,Nagasawa, T.,Nikaido, M.
    • Organizer
      日本進化学会第25回大会, 琉球大学共通教育棟, 沖縄県市町村自治会館
    • Related Report
      2023 Annual Research Report
  • [Presentation] 哺乳類における塩基性アミノ酸トランスポーター遺伝子の多様化2023

    • Author(s)
      中村遥奈、二階堂雅人
    • Organizer
      日本進化学会第25回大会, 琉球大学共通教育棟, 沖縄県市町村自治会館
    • Related Report
      2023 Annual Research Report
  • [Presentation] Ancient standing genetic variation facilitated the adaptive radiation of Lake Victoria cichlids2023

    • Author(s)
      Nakamura, H., Aibara, M., Mrosso, H.D.J., Mzighani, S.I., Nikaido,M.
    • Organizer
      XXIIIrd International Congress of Genetics, Melbourne AUS
    • Related Report
      2023 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Molecular evolution of the OMP genes after the whole genome duplication in teleost fish2023

    • Author(s)
      Nagasawa, T., Fujisaki, H., Nikaido, M.
    • Organizer
      XXIIIrd International Congress of Genetics, Melbourne AUS
    • Related Report
      2023 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Olfactory receptor genes expressed in whale’s main olfactory organ: an implication for sense of smell2023

    • Author(s)
      Hirose, A., Nikaido, M., Nakamura, G., Fujise, Y., Kato, H., Kishida, T.
    • Organizer
      XXIIIrd International Congress of Genetics, Melbourne AUS
    • Related Report
      2023 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Did egg-eater lose the ecological competition? Strong population bottleneck in matumbi hunter the paedophage2023

    • Author(s)
      Imamoto, M., Nakamura, H., Aibara, M., Itoh, T., Nikaido, M.
    • Organizer
      XXIIIrd International Congress of Genetics, Melbourne AUS
    • Related Report
      2023 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Function Divergence of Cichlid Candidate Pheromone Receptor V1R22023

    • Author(s)
      Kawamura, R., Murata, K., Touhara, K., Nikaido, M.
    • Organizer
      XXIIIrd International Congress of Genetics, Melbourne AUS
    • Related Report
      2023 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 魚類に見られる鼻管の機能解明2023

    • Author(s)
      伊藤隆晃, 西浦賀乃子, 木村優希, 中牟田信明, 長澤竜樹, 二階堂雅人
    • Organizer
      第11回Tokyo Vertebrate Morphology Meeting 東京慈恵会医科大学
    • Related Report
      2023 Annual Research Report
  • [Presentation] Genetic mechanisms of lip hypertrophy in East African cichlids2023

    • Author(s)
      Machii, N., Hatashima R., Aibara M., Nagasawa T., Nikaido M.
    • Organizer
      nternational Symposium on Evolutionary Genomics and Bioinformatics 2023 国立清華大学(台湾)
    • Related Report
      2023 Annual Research Report
  • [Presentation] 東アフリカ産シクリッドのV1R2受容体のリガンド分化2023

    • Author(s)
      河村理輝,二階堂雅人
    • Organizer
      第8回 ケモビ研究会
    • Related Report
      2022 Research-status Report
  • [Presentation] Exceptional evolutionary history and population bottleneck of egg eating cichlids in Lake Victoria2022

    • Author(s)
      Imamoto, M., Nakamura, H., Aibara, M., Ito, T. and Nikaido, M.
    • Organizer
      Cichlid Science 2022
    • Related Report
      2022 Research-status Report
  • [Presentation] 東アフリカ産シクリッドにおける肥大化した唇の分子実態解明2022

    • Author(s)
      待井長敏, 畑島諒, 中村遥奈, 丹羽達也, 長澤竜樹, 二階堂雅人
    • Organizer
      日本進化学会第24回沼津大会
    • Related Report
      2022 Research-status Report
  • [Presentation] 卵泥棒・マタンビハンターのボトルネックと進化史2022

    • Author(s)
      今本南,中村遥奈,相原光人,伊藤武彦,二階堂雅人
    • Organizer
      日本進化学会第24回沼津大会
    • Related Report
      2022 Research-status Report
  • [Presentation] 免疫関連遺伝子の発現消失がもたらしたシクリッドの唇肥大化平行進化2022

    • Author(s)
      畑島諒, 豊田敦, 梶谷嶺, 伊藤武彦, 二階堂雅人
    • Organizer
      日本進化学会第24回沼津大会
    • Related Report
      2022 Research-status Report
  • [Presentation] シクリッドにおけるV1R遺伝子の種間比較解析2022

    • Author(s)
      滝隼輔,二階堂雅人
    • Organizer
      日本進化学会第24回沼津大会
    • Related Report
      2022 Research-status Report
  • [Presentation] ヴィクトリア湖産シクリッドにおけるcollagen 6a6遺伝子の機能解析2022

    • Author(s)
      久保田和樹,中村遥奈,長澤竜樹,二階堂雅人
    • Organizer
      日本進化学会第24回沼津大会
    • Related Report
      2022 Research-status Report
  • [Presentation] 免疫システムがもたらしたシクリッドの唇肥大化平行進化2022

    • Author(s)
      畑島諒, 待井長敏, 豊田敦, 梶谷嶺, 長澤竜樹, 伊藤武彦, 二階堂雅人
    • Organizer
      第2回日本遺伝学会春の分科会
    • Related Report
      2021 Research-status Report
  • [Presentation] 東アフリカ産シクリッドのV1R2受容体の多型によるリガンド受容能の違いの検証2022

    • Author(s)
      河村理輝, 村田健, 東原和成, 二階堂雅人
    • Organizer
      第2回日本遺伝学会春の分科会
    • Related Report
      2021 Research-status Report
  • [Presentation] 卵を食べるシクリッドの系統的起源2022

    • Author(s)
      今本南,中村遥奈,相原光人,伊藤武彦,二階堂雅人
    • Organizer
      日本動物学会関東支部第74回大会
    • Related Report
      2021 Research-status Report
  • [Presentation] 肥厚した唇を持つヴィクトリア湖シクリッドの進化史推定2022

    • Author(s)
      中村遥奈,相原光人,伊藤武彦,二階堂雅人
    • Organizer
      日本動物学会関東支部第74回大会
    • Related Report
      2021 Research-status Report
  • [Presentation] ヴィクトリア湖産シクリッド嗅上皮の外部形態の種間比較2022

    • Author(s)
      鈴木海理, 相原光人, 二階堂雅人
    • Organizer
      日本動物学会関東支部第74回大会
    • Related Report
      2021 Research-status Report
  • [Presentation] シクリッドにおけるV1R遺伝子の網羅的解析2022

    • Author(s)
      滝隼輔,二階堂雅人
    • Organizer
      日本動物学会関東支部第74回大会
    • Related Report
      2021 Research-status Report
  • [Presentation] マルチオミクス解析で探る「シクリッドの唇肥大化」の平行進化メカニズム2022

    • Author(s)
      待井長敏,畑島諒,中村遥奈,丹羽達也,田口 英樹,長澤竜樹,二階堂雅人
    • Organizer
      日本動物学会関東支部第74回大会
    • Related Report
      2021 Research-status Report
  • [Presentation] 東アフリカ産シクリッドのフェロモン受容体候補V1R2受容体の多型による選択的交配の可能性の検証2021

    • Author(s)
      河村理輝,村田健,清水翔子,川辺悠士郎,二階堂雅人
    • Organizer
      日本味と匂学会第55回福岡大会
    • Related Report
      2021 Research-status Report
  • [Presentation] 全ゲノムから迫るビクトリア湖産シクリッド Haplochromis sp. “matumbi hunter”の集団史2021

    • Author(s)
      今本南,中村遥奈,相原光人,伊藤武彦,二階堂雅人
    • Organizer
      日本遺伝学会第93回大会
    • Related Report
      2021 Research-status Report
  • [Presentation] ヴィクトリア湖産シクリッド Haplochromis chilotes の集団遺伝解析2021

    • Author(s)
      中村遥奈,相原光人,二階堂雅人
    • Organizer
      日本遺伝学会第93回大会
    • Related Report
      2021 Research-status Report
  • [Presentation] シクリッドフェロモン受容体 V1R2 の成長に伴う発現量解析2021

    • Author(s)
      川辺悠士郎,清水翔子,河村理輝,二階堂雅人
    • Organizer
      日本遺伝学会第93回大会
    • Related Report
      2021 Research-status Report
  • [Presentation] 匂い暴露による東アフリカ産シクリッドの嗅神経細胞の応答2021

    • Author(s)
      河村理輝,二階堂雅人
    • Organizer
      日本動物学会第92回大会
    • Related Report
      2021 Research-status Report
  • [Presentation] シクリッドの適応形質・肥大化した唇の遺伝的基盤の解明2021

    • Author(s)
      待井長敏, 畑島諒, 中村遥奈, 長澤竜樹, 二階堂雅人
    • Organizer
      日本動物学会第92回大会
    • Related Report
      2021 Research-status Report
  • [Presentation] 東アフリカ産シクリッドにおける遺伝子系統樹間の大規模な不一致2021

    • Author(s)
      二階堂雅人
    • Organizer
      日本進化学会第23回東京大会シンポジウム
    • Related Report
      2021 Research-status Report
    • Int'l Joint Research
  • [Presentation] Whole-genome comparative analyses among subpopulations in Lake Victoria cichlid, Haplochromis chilotes2021

    • Author(s)
      Nakamura, H., Aibara, M. and Nikaido, M.
    • Organizer
      The 2nd AsiaEvo Conference
    • Related Report
      2021 Research-status Report
    • Invited
  • [Presentation] Possibility of assortative mating via putative pheromone receptor V1R2 in East African Cichlid2021

    • Author(s)
      Kawamura, R., Murata K., Shimizu, S., Kawabe, Y., Touhara, K., and Nikaido, M.
    • Organizer
      The 2nd AsiaEvo Conference
    • Related Report
      2021 Research-status Report
    • Invited
  • [Presentation] A key factor for parallel evolution of hypertrophied lips in East African cichlid fishes2021

    • Author(s)
      Hatashima, R., Toyoda, A., Kajitani, R. Itoh, T. and Nikaido, M.
    • Organizer
      The 2nd AsiaEvo Conference
    • Related Report
      2021 Research-status Report
    • Invited
  • [Presentation] Evolutionary history of egg hunting cichlids in Lake Victoria2021

    • Author(s)
      Imamoto, M., Nakamura, H., Aibara, M., Ito, Takehiko. and Nikaido, M.
    • Organizer
      The 2nd AsiaEvo Conference
    • Related Report
      2021 Research-status Report
    • Invited
  • [Presentation] Elucidating genetic mechanism of cichlid hypertrophic lips, using differentially expressed gene analysis2021

    • Author(s)
      Machii, N., Hatashima, R., Nakamura, H., Nagasawa, T. and Nikaido, M.
    • Organizer
      The 2nd AsiaEvo Conference
    • Related Report
      2021 Research-status Report
    • Invited
  • [Presentation] 東アフリカ産シクリッドで見られる唇肥大化平行進化の分子メカニズム2021

    • Author(s)
      畑島諒, 豊田敦, 梶谷嶺, 伊藤武彦, 二階堂雅人
    • Organizer
      日本進化学会第23回東京大会
    • Related Report
      2021 Research-status Report
  • [Presentation] 卵泥棒の起源からシクリッドの適応放散を探る2021

    • Author(s)
      今本南,中村遥奈,相原光人,伊藤武彦,二階堂雅人
    • Organizer
      日本進化学会第23回東京大会
    • Related Report
      2021 Research-status Report
  • [Presentation] 東アフリカシクリッドにおける唇肥大化の遺伝的基盤の解明2021

    • Author(s)
      待井長敏, 畑島諒, 中村遥奈, 長澤竜樹, 二階堂雅人
    • Organizer
      日本進化学会第23回東京大会
    • Related Report
      2021 Research-status Report
  • [Presentation] 東アフリカ産シクリッドの唇肥大化に関わる平行進化の遺伝的機構2021

    • Author(s)
      二階堂雅人
    • Organizer
      第43回日本分子生物学会年会ワークショップ
    • Related Report
      2020 Research-status Report
    • Invited
  • [Presentation] ヴィクトリア湖に生息する卵・稚魚食性シクリッド Haplochromis sp. “matumbi hunter” の進化の歴史2021

    • Author(s)
      今本南,中村遥奈,相原光人,伊藤武彦,二階堂雅人
    • Organizer
      日本動物学会関東支部第73回大会
    • Related Report
      2020 Research-status Report
  • [Presentation] 東アフリカ産シクリッドにおける VI 型コラーゲンの進化2021

    • Author(s)
      中村遥奈,相原光人,二階堂雅人
    • Organizer
      日本動物学会関東支部第73回大会
    • Related Report
      2020 Research-status Report
  • [Presentation] 熱帯魚シクリッドの匂い受容の検出2021

    • Author(s)
      河村理輝,二階堂雅人
    • Organizer
      第7回 ケモビ研究会
    • Related Report
      2020 Research-status Report
  • [Book] 第4章 霊長類の遺伝」『霊長類学の百科事典』(日本霊長類学会 編集)2023

    • Author(s)
      二階堂雅人 分担執筆
    • Publisher
      丸善出版
    • Related Report
      2023 Annual Research Report
  • [Book] あらゆる脊椎動物が共有するフェロモン受容体「科学」2023

    • Author(s)
      二階堂雅人 分担執筆
    • Publisher
      岩波出版
    • Related Report
      2023 Annual Research Report
  • [Remarks] 二階堂研究室HP

    • URL

      http://www.nikaido.bio.titech.ac.jp/

    • Related Report
      2023 Annual Research Report
  • [Remarks] 二階堂研究室

    • URL

      http://www.nikaido.bio.titech.ac.jp

    • Related Report
      2020 Research-status Report
  • [Remarks] シクリッドゲノム中に適応進化の痕跡を発見(プレスリリース)

    • URL

      https://www.titech.ac.jp/news/2021/049658.html

    • Related Report
      2020 Research-status Report

URL: 

Published: 2020-10-29   Modified: 2025-01-30  

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