| Project/Area Number |
20KK0222
|
|---|
| Research Category |
Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
|
| Allocation Type | Multi-year Fund |
|---|
| Review Section |
Medium-sized Section 58:Society medicine, nursing, and related fields
|
|---|
| Research Institution | University of Miyazaki |
|---|
Principal Investigator |
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
古川 誠志 宮崎大学, 医学部, 准教授 (10347073)
村岡 純輔 宮崎大学, 医学部, 助教 (20894265)
澤田 浩武 宮崎大学, 医学部, 教授 (40332895)
柳 裕哉 宮崎大学, 医学部, 特別助教 (70888106)
桂木 真司 宮崎大学, 医学部, 教授 (50521283)
|
|---|
| Project Period (FY) |
2020-10-27 – 2025-03-31
|
| Project Status |
Granted (Fiscal Year 2023)
|
| Budget Amount *help |
¥18,590,000 (Direct Cost: ¥14,300,000、Indirect Cost: ¥4,290,000)
Fiscal Year 2024: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2023: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2022: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2021: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2020: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
|
|---|
| Keywords | Pregnancy / Environment / Cohort study / Child development / water pollution / pregnancy / child birth / health / 農薬 / インド / 水質汚染 / 妊婦健康 / 小児健康 |
|---|
| Outline of Research at the Start |
インドケーララ州では妊娠・出産の異常や出生児の奇形の発生が多く報告されている。しかし原因は明らかになっていない。そこで、インドケーララ州を調査地域とし、Niite大学と共同で、地下水中の化学物質の妊娠・出産および小児への影響を評価する本研究（コホート調査）を計画した。これまでに行ってきたヒ素汚染地域での活動、小児への調査経験を活かし、地下水汚染化学物質による妊婦・出生児への健康調査を実施し、新たな知見を得るとともに、調査・対策への技術支援を行う。これは地下水汚染問題を抱える途上国への新たな支援モデル（妊婦および小児への健康問題を課題としたアプローチ）である。
|
| Outline of Annual Research Achievements |
So far, health status of 500 pregnant women and 150 children have been compiled, and the data was compared with hydrochemical, physicochemical, and microbiological status of soil and water.
Areas of Belapu, Pejawara, and Belma in Mangaluru; Manjeshwara and Neeleshwara in Kasargod district have high iron content in water and above average levels of microbiological loadings in soil. Its relevance to pregnancy and child health status is being evaluated. 12 abnormal deliveries were recorded in these areas, however no significant changes were observed in child health.
Correlation between these environmental parameters and their impact on the health status of pregnant women and subsequent child birth and helath will be compiled, and data generated for publications.
|
| Current Status of Research Progress |
Current Status of Research Progress
2: Research has progressed on the whole more than it was originally planned.
Reason
Project is progressing smoothly, with perfect coordination between Nitte University hospital, the project lab Cellomic lab, and expertise and support from University of Miyazaki.
|
| Strategy for Future Research Activity |
As part of the project objective, continuous evaluation of child health is necessary. So far, this year, health status of 150 children has been completed. Survey samples of 200 more children is expected to be collected, and evaluated for biochemical analysis including hair sample analysis. Physical health check up also will be conducted. Child health parameters will be evaluated with the help of computer-aided intelligence programs and compared with geochemical and physicochemical status of the water and soil.
Nitte University is developing a comprehensive plan to overcome any long-term issue, with expertise advice from gynecologists and pediatricians, in coordination with experts from the University of Miyazaki.
|
