Development of DNA-Chip-Based Electronic Devices for Nanobio Sensing Applications
Project/Area Number |
21200034
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Research Category |
Grant-in-Aid for Scientific Research on Innovative Areas (Research a proposed research project)
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Allocation Type | Single-year Grants |
Research Field |
Analytical chemistry
Nanomaterials/Nanobioscience
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Research Institution | Kyushu University |
Principal Investigator |
NAKANO Kouji 九州大学, 工学研究院応用化学部門, 准教授 (10180324)
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Project Period (FY) |
2009 – 2011
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Project Status |
Completed (Fiscal Year 2011)
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Budget Amount *help |
¥25,220,000 (Direct Cost: ¥19,400,000、Indirect Cost: ¥5,820,000)
Fiscal Year 2011: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2010: ¥10,010,000 (Direct Cost: ¥7,700,000、Indirect Cost: ¥2,310,000)
Fiscal Year 2009: ¥10,920,000 (Direct Cost: ¥8,400,000、Indirect Cost: ¥2,520,000)
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Keywords | ナノバイオ / DNA / 自己組織化 / 分子認識 / バイオセンサー / 遺伝子センサー / 分子エレクトロニクス / 走査プローブ顕微鏡 / DNA / 走査プローブ顕徽鏡 / 走査プローズ顕微鏡 |
Research Abstract |
DNA-based molecular device that is capable of responding to biological molecular recognition events was tackled for futuristic nano-, bio-device developments based on in-situ electoconductive modification of DNA self-assembly. Some direct or indirect assistance necessary to the goal were successfully developed; novel psoralen compounds that enable versatile functionalization of DNA duplexes by covalent conjugation, single-molecule assay for various DNA affinity reactions including single-nucleotide polymorphism using atomic force microscope, new types of bottom-up, supramolecular DNA nanomaterials based on dendrimer formation of three-way junction DNA, and etc. We are committed to taking on the challenges by installing the DNA dendrimer materials into interdigitated array electrode to provide state-of-the-art, molecularly responsive devices adaptable to various bioanalytical purposes.
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Report
(4 results)
Research Products
(54 results)
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[Journal Article] Structure-Reactivity Relationship of Piperidine Nitroxide: Electrochemical, ESR and Computational Studies2011
Author(s)
T. Yamasaki, F. Mito, Y. Ito, S. Pansian, Y. Konoshita, K. Nakano, R. Murugesan, K. Sakai, H. Utsumi, K.Yamada
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Journal Title
J. Organic Chemistry
Volume: Vol. 76, No. 2
Pages: 435-440
Related Report
Peer Reviewed
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