Development of micro total analysis system with an organic light-emitting diode and an organic photodiode for fluorescence detection
| Project/Area Number |
21200056
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| Research Category |
Grant-in-Aid for Scientific Research on Innovative Areas (Research a proposed research project)
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| Allocation Type | Single-year Grants |
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| Research Field |
Analytical chemistry
Functional materials/Devices
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| Research Institution | Tokyo Metropolitan University |
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Principal Investigator |
NAKAJIMA Hizuru 首都大学東京, 都市環境科学研究科, 准教授 (10432858)
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| Co-Investigator(Kenkyū-buntansha) |
IMATO Toshihiko 九州大学, 工学研究科, 教授 (50117066)
内山 一美 首都大学東京, 都市環境科学研究科, 教授 (40151899)
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥30,940,000 (Direct Cost: ¥23,800,000、Indirect Cost: ¥7,140,000)
Fiscal Year 2011: ¥10,010,000 (Direct Cost: ¥7,700,000、Indirect Cost: ¥2,310,000)
Fiscal Year 2010: ¥10,010,000 (Direct Cost: ¥7,700,000、Indirect Cost: ¥2,310,000)
Fiscal Year 2009: ¥10,920,000 (Direct Cost: ¥8,400,000、Indirect Cost: ¥2,520,000)
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| Keywords | μTAS / 有機EL / 有機フォトダイオード / CD / ELISA / フォトダイオード / 検出法 / オンサイト測定 / Lab-on-a-chip / マイクロチップ / 化学センサ / バイオセンサ / 蛍光 |
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| Research Abstract |
A novel micro total analysis system with an organic light-emitting diode and an organic photodiode for fluorescence detection has been developed in order to miniaturize the total size of the analytical system. A compact disk (CD)-type microfluidic device and the solution sending system using centrifugal force was developed. The enzyme-linked immunosorbent assay (ELISA) using the developed system was evaluated. The quantitative values obtained on the developed system were in excellent agreement with that on the conventional ELISA using a 96-well microtiter plate. Since the micro total analysis system developed in this study does not require large size and expensive devices such as laser, microscope, pump and valve, the system would be useful for on-site analysis, such as environmental monitoring, food safety testing and point-of-care testing.
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Report
(4 results)
Research Products
(57 results)
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[Journal Article] Performance of an organic photodiode as an optical detector and its application to fluorometric flow-immunoassay for IgA2012
Author(s)
Mayo Miyake, Hizuru Nakajima, Akihide Hemmi, Masayuki Yahiro, Chihaya Adachi, Nobuaki Soh, Ryoichi Ishimatsu, Koji Nakano, Katsumi Uchiyama, Toshihiko Imato
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Journal Title
Talanta,(Available online 10 February 2012)
Volume: (in press)
Related Report
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[Journal Article] An Integrated Enzyme-linked Immunosorbent Assay System with an Organic Light-emitting Diode and a Chargecoupled Device for Fluorescence Detection2011
Author(s)
Hizuru Nakajima, Yukiko Okuma, Kazuhiro Morioka, Mayo Miyake, Akihide Hemmi, Tatsuya Tobita, Masayuki yahiro, Daisuke Yokoyama, Chihaya Adachi, Nobuaki Soh, Koji Nakano, Shuhua Xue, Hulie Zeng, Katsumi Uchiyama, Toshihiko Imato
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Journal Title
J. Sep. Sci.
Volume: 34
Pages: 2906-2912
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[Presentation] A surface plasmon resonance sensor on a compact disk-like microfluidic device2011
Author(s)
Akihide Hemmi, Tatsuya Tobita, Takashi Usui, Akihiro Moto, Nobuaki Soh, Koji Nakano, Toshihiko Imato, Katsumi Uchiyama, Hizuru Nakajima
Organizer
Pittcon2011, Atlanta
Place of Presentation
Georgia, USA
Year and Date
2011-03-13
Related Report
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[Presentation] An integrated fluorescence detection system using organic light emitting diodes as light source2010
Author(s)
Mayo Miyake, Yukiko Okuma, Akihide Hemmi, Daisuke Yokoyama, Masayuki Yahiro, Chihaya Adachi, Toshihiko Imato, Katsumi Uchiyama, and Hizuru Nakajima
Organizer
Pacifichem 2010
Place of Presentation
Honolulu, Hawaii, USA
Year and Date
2010-12-19
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[Presentation] Optical Detection System Combined with Organic Light Emitting Diode and Organic Photodiode for Micro-Flow Analysis2009
Author(s)
Y.Okuma, M.Miyake, N.Soh, K.Nakano, D.Yokoyama, M.Yahiro, C.Adachi, A.Hemmi, H.Nakajima, K.Uchiyama, T.Imato
Organizer
FLOW ANALYSIS XI
Place of Presentation
スペイン マヨルカ島
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