A Twin Study on Sociability and Mental Health : A Bridge between Genes and Brain Activities
Project/Area Number |
21223002
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Research Category |
Grant-in-Aid for Scientific Research (S)
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Allocation Type | Single-year Grants |
Research Field |
Educational psychology
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Research Institution | Keio University |
Principal Investigator |
ANDO Juko 慶應義塾大学, 文学部, 教授 (30193105)
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Co-Investigator(Kenkyū-buntansha) |
TODA Toda 神戸大学, 大学院・医学研究科, 教授 (30262025)
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Co-Investigator(Renkei-kenkyūsha) |
KAWAI Yasuyo (MINAGAWA Yasuyo) 慶應義塾大学, 大学院・社会学研究科 (90521732)
FUJISAWA Keiko 慶應義塾大学, 文学部, 助教 (00453530)
ONO Yutaka 国立精神・神経医療研究センター, 認知行動療法センター, 所長 (70138098)
HIRAISHI Kai 京都大学, こころの未来研究センター, 助教 (50343108)
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Project Period (FY) |
2009 – 2011
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Project Status |
Completed (Fiscal Year 2011)
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Budget Amount *help |
¥212,290,000 (Direct Cost: ¥163,300,000、Indirect Cost: ¥48,990,000)
Fiscal Year 2011: ¥69,160,000 (Direct Cost: ¥53,200,000、Indirect Cost: ¥15,960,000)
Fiscal Year 2010: ¥68,900,000 (Direct Cost: ¥53,000,000、Indirect Cost: ¥15,900,000)
Fiscal Year 2009: ¥74,230,000 (Direct Cost: ¥57,100,000、Indirect Cost: ¥17,130,000)
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Keywords | 行動遺伝学 / 双生児法 / 児童期 / 青年期 / 認知能力 / 社会性 / 言語能力 / 脳機能 |
Research Abstract |
The purpose of this research project is to clarify genetic and environmental influences on developmental processes of sociability and mental health conditions by two independent twin cohorts, one for childhood and the other for adolescence and adulthood, in a longitudinal way. The results revealed that development of cognitive abilities, problem behaviors and mental health conditions were influenced by genetic changes as well as various kinds of interaction between genes and family/cultural environment. Scientific foundations to identify genes and their expression and to clarify brain structure and functions related to cognitive functions were established.
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Report
(3 results)
Research Products
(84 results)
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[Journal Article] The genetic and environmental relationships between head circumference growth in the first year of life and sociocognitive development in the second year : A longitudinal twin study2012
Author(s)
Fujisawa, K., Ozaki, K., Suzuki, K., Yamagata, Y., Kawahashi, I. & Ando, J
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Journal Title
Developmental Science
Volume: 15(1)
Pages: 99-112
Related Report
Peer Reviewed
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[Journal Article] Functional hemispheric speciali-zation in processing phonemic and prosodic auditory changes in neonates2011
Author(s)
Arimitsu, T., Uchida-Ota, M., Yagihashi, T., Kojima, S., Watanabe, S., Hokuto, I., Ikeda, K., Takahashi, T., Minagawa-Kawai, Y
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Journal Title
Frontiers in Psychology
Volume: 2
Pages: 202-202
Related Report
Peer Reviewed
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[Journal Article] The generality of personality heritability : Big-Five trait heritability predicts response time to trait items.2010
Author(s)
Ekehammar, B., Akrami, N., Hedlund, L.E., Yoshimura, K., Ono, Y., Ando, J., Yamagata, S.
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Journal Title
Journal of Individual Differences
Volume: 31
Pages: 209-214
Related Report
Peer Reviewed
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[Presentation] Genome-Wide DNA Methylation and Gene Expression Analyses of Monozygotic Twins Discordant for Intelligence Levels2011
Author(s)
Yu, CC., Furukawa, M., Kobayashi, K., Shikishima, C. Cha, PC., Sese, J., Sugawara, H., Iwamoto, K., Kato, T., Ando, J & Toda, T
Organizer
日本人類遺伝学会第56回大会
Place of Presentation
千葉(幕張メッセ)
Year and Date
2011-11-12
Related Report
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[Presentation] Genome-Wide DNA Methylation and Gene Expression Analyses of Monozygotic Twins Discordant for Intelligence Levels2011
Author(s)
CC Yu, M Furukawa, K Kobayashi, C Shikishima, PC Cha, J Sese, H Sugawara, K Iwamoto, T Kato, J Ando, T Toda
Organizer
日本人類遺伝学会第56回大会
Place of Presentation
幕張メッセ(千葉)
Year and Date
2011-11-12
Related Report
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[Presentation] The Effect of Sibling Relationship on Individual Adjustment in Japanese Twin Children Compared with Singletons2011
Author(s)
Nozaki, M., Fujisawa, K.K., Ando, J., Hasegawa, T
Organizer
The 15th European Conference on Developmental Psychology, Bergen, Norway,, 2011
Place of Presentation
Bergen, Norway
Related Report
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[Presentation] Heritability of decisions and outcomes on public goods games2011
Author(s)
Hiraishi, K., Shikishima, C., Takahashi, Y., Yamagata, S., Sugimoto, Y., Ando, J
Organizer
Human Behavior and Evolution Society 23th Annual Conference
Place of Presentation
Montpellier, France
Related Report
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[Presentation] Genetic correlates of syllogism-solving ability.2010
Author(s)
Shikishima, C., Yamagata, S., Hiraishi, K., Sugimoto, Y., Ando, J.
Organizer
40th Annual Meeting of the Behavior Genetics Association
Place of Presentation
Seoul, South Korea
Related Report
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[Presentation] GE interaction analysis on the univariate ACDE model.2010
Author(s)
Ozaki, K., Fujisawa, K.Keiko., Yamagata, S., Takahashi, Y., Sasaki, S., Shikishima, C., Ando J.
Organizer
40th Annual Meeting of the Behavior Genetics Association
Place of Presentation
Seoul, South Korea
Related Report
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[Presentation] Do stressful life events moderate genetic and environmental covariance on personality and psychiatric symptoms? : Bivariate gene-environment interaction approach2010
Author(s)
Takahashi, Y., Yamagata, S., Ozaki, K., Shikishima, C., Nonaka, K., Ando, J.
Organizer
40th Annual Meeting of the Behavior Genetics Association
Place of Presentation
Seoul, South Korea
Related Report
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[Presentation] A longitudinal twin study on the environmental association between behavior problems and parenting2010
Author(s)
Yamagata, S., Takahashi, Y., Ozaki, K., Fujisawa, K.K., Nonaka, K., Ando, J.
Organizer
40th Annual Meeting of the Behavior Genetics Association
Place of Presentation
Seoul, South Korea
Related Report
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[Presentation] Genome-wide gene expression and DNA methylation analyses of significantly discordant monozygotic twins for cognitive ability.2010
Author(s)
Kobayashi, K., Furukawa, M., Yu, C.-c., Shikishima, C., Sese, J., Sugawara, H., Iwamoto, K., Kato, Y., Ando, J., Toda, T.
Organizer
American Society of Human Genetics 60th Annual Meeting
Place of Presentation
Washington DC, USA
Related Report
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[Presentation] Genetic analysis of monozygotic twins discordant for cognitive abilities2009
Author(s)
Kobayashi, K., Furukawa, M., Yu, C.-C., Shikishima, C., Ando, J., & Toda, T
Organizer
American Society of Human Genetics 59th Annual Meeting
Place of Presentation
Honolulu, USA
Year and Date
2009-10-22
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