Integration of cortical micro and macro circuits
| Project/Area Number |
21240030
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| Research Category |
Grant-in-Aid for Scientific Research (A)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Neuroscience in general
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| Research Institution | National Institute for Physiological Sciences |
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Principal Investigator |
KAWAGUCHI Yasuo 生理学研究所, 大脳皮質機能研究系, 教授 (40169694)
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| Co-Investigator(Renkei-kenkyūsha) |
TAKADA Mieko 生理学研究所, 大脳皮質機能研究系, 助教 (30435531)
KUBOTA Yoshiyuki 生理学研究所, 大脳皮質機能研究系, 准教授 (90192567)
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| Project Period (FY) |
2009 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥36,400,000 (Direct Cost: ¥28,000,000、Indirect Cost: ¥8,400,000)
Fiscal Year 2012: ¥13,000,000 (Direct Cost: ¥10,000,000、Indirect Cost: ¥3,000,000)
Fiscal Year 2011: ¥13,000,000 (Direct Cost: ¥10,000,000、Indirect Cost: ¥3,000,000)
Fiscal Year 2010: ¥10,400,000 (Direct Cost: ¥8,000,000、Indirect Cost: ¥2,400,000)
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| Keywords | 大脳皮質 / 局所回路 / 錐体細胞 / GABA / シナプス結合 / 皮質外投射 / 大脳基底核 / 新皮質 / 前頭皮質 / 視床 / 振動 / スピンドル / 網様核 / 橋核 / 線条体 / 逆行性標識 / シナプス電流 / セロトニン / 電子顕微鏡 / 介在細胞 / FS細胞 |
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| Research Abstract |
Using neocortex, especially frontal cortex, and basal ganglia, animals select the most appropriate actions according the past action and its result. To understand this brain process, we should know the neuron composition of the frontal cortex and their synaptic interactions. This research has clarified the functional organization and synaptic connection rules of output cells projecting to the basal ganglia and other subcortical structures. These findings indicate that the neocortical local circuit consists of connection subnetworks organized according to diverse extracortical projections.
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Report
(5 results)
Research Products
(105 results)
