|Budget Amount *help
¥46,930,000 (Direct Cost: ¥36,100,000、Indirect Cost: ¥10,830,000)
Fiscal Year 2012: ¥9,880,000 (Direct Cost: ¥7,600,000、Indirect Cost: ¥2,280,000)
Fiscal Year 2011: ¥10,790,000 (Direct Cost: ¥8,300,000、Indirect Cost: ¥2,490,000)
Fiscal Year 2010: ¥10,790,000 (Direct Cost: ¥8,300,000、Indirect Cost: ¥2,490,000)
Fiscal Year 2009: ¥15,470,000 (Direct Cost: ¥11,900,000、Indirect Cost: ¥3,570,000)
We have investigated how the outputs from the basal ganglia contribute to the activity in the thalamus and motor cortices, and their relations to the movement disorders and their therapy. Basal ganglia outputs inhibit thalamic activity. However, repetitive pallidal stimulation sometimes induced excitation in the thalamus and cortex. The mechanism of deep brain stimulation targeting the globus pallidus was considered to be the interruption of abnormal information flow from the basal ganglia to the thalamus.