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Development of a photo-driven molecular machine with photo-responsive DNA

Research Project

Project/Area Number 21241031
Research Category

Grant-in-Aid for Scientific Research (A)

Allocation TypeSingle-year Grants
Section一般
Research Field Nanomaterials/Nanobioscience
Research InstitutionNagoya University

Principal Investigator

ASANUMA Hiroyuki  名古屋大学, 工学研究科, 教授 (20282577)

Co-Investigator(Kenkyū-buntansha) LIANG Xingguo  名古屋大学, 大学院・工学研究科, 准教授 (60447828)
Project Period (FY) 2009 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥46,800,000 (Direct Cost: ¥36,000,000、Indirect Cost: ¥10,800,000)
Fiscal Year 2012: ¥10,790,000 (Direct Cost: ¥8,300,000、Indirect Cost: ¥2,490,000)
Fiscal Year 2011: ¥10,790,000 (Direct Cost: ¥8,300,000、Indirect Cost: ¥2,490,000)
Fiscal Year 2010: ¥10,530,000 (Direct Cost: ¥8,100,000、Indirect Cost: ¥2,430,000)
Fiscal Year 2009: ¥14,690,000 (Direct Cost: ¥11,300,000、Indirect Cost: ¥3,390,000)
Keywords光応答性 DNA / アゾベンゼン / 分子マシン / 光制御 / 可視光応答 / DNAエンザイム / 緑色蛍光性タンパク質 / 無細胞タンパク質合成系 / 遺伝子発現 / DNA / ナノマシン / 光応答性
Research Abstract

In this project, we aimed at creating new photo-driven DNA machines with photo-responsive DNA involving azobenzenes. First, we designed a newly modified azobenzene that enables efficient photo-regulation of DNA hybridization. We found that modification of a distal benzene ring at two ortho-positions was effective for the improvement of both photoregulatory efficiency and thermal stability of cis-form. Furthermore, we also clarified that the modified duplex of alternating base-pair and azobenzene residues allowed complete photo-regulation of DNA hybridization only by light-irradiation. Based on these results, we successfully constructed 1) photo-driven DNA machine that can reversibly digest target RNA, 2) photo-degradable DNA nano-capsule, and 3) DNA machine that can move like seesaw by the combination with visible light-responsive azobenzene.

Report

(5 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • 2009 Annual Research Report
  • Research Products

    (263 results)

All 2013 2012 2011 2010 2009 Other

All Journal Article (48 results) (of which Peer Reviewed: 44 results) Presentation (202 results) (of which Invited: 4 results) Book (6 results) Remarks (2 results) Patent(Industrial Property Rights) (5 results)

  • [Journal Article] Photoswitch nucleic acid catalytic activity by regulating topological structure with a universal supra-photoswitch2013

    • Author(s)
      Liang, X.G.; Zhou, M.G.; Kato, K.; Asanuma, H.
    • Journal Title

      ACS Synth. Biol.

      Volume: 2 Pages: 194-202

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Evaluation of intrinsic spectroscopic properties of chromophore assemblies by shielding with cyclohexyl base pairs within a DNA duplex2013

    • Author(s)
      Kashida, H.; Higashiyama, N.; Kato, T.; Asanuma, H.
    • Journal Title

      Bioorg. Med. Chem.

      Volume: 21

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Photon-fueled DNA nanodevice carrying two different photoswitches2012

    • Author(s)
      Nishioka, H.; Liang, X. G.; Kato, T.; Asanuma, H.
    • Journal Title

      Angew. Chem. Int. Ed.

      Volume: 51 Pages: 1165-1168

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Development of a robust model system of FRET using base-surrogates tethering fluorophores for strict control of their position and orientation within DNA duplex.2012

    • Author(s)
      Kato, T.; Kashida, H.; Kishida, H.; Yada, H.; Okamoto, H.; Asanuma, H.;
    • Journal Title

      J. Am. Chem. Soc.

      Volume: 135 Issue: 2 Pages: 741-750

    • DOI

      10.1021/ja309279w

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A model of elongation of short DNA sequence by thermophilic DNA polymerase under isothermal conditions.2012

    • Author(s)
      Kato, T.; Liang, X.G.; Asanuma, H.
    • Journal Title

      Biochemistry

      Volume: 51 Issue: 40 Pages: 7846-7853

    • DOI

      10.1021/bi3010413

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Reversed assembling of dyes in RNA duplex compared with those in DNA2012

    • Author(s)
      T. Fujii, M. Urushihara, H. Kashida, H. Ito, X. G. Liang, M. Yagi-Utsumi, K. Kato, H. Asanuma,
    • Journal Title

      Chemistry - A European Journal

      Volume: 18 Issue: 42 Pages: 13304-13313

    • DOI

      10.1002/chem.201201956

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Quencher-free linear probe with multiple fluorophores on acyclic scaffold2012

    • Author(s)
      Asanuma, H.; Akahane, M.; Kondo, N.; Osawa, T.; Kato, T.; Kashida, H.
    • Journal Title

      Chem. Sci.

      Volume: 3 Issue: 11 Pages: 3165-3169

    • DOI

      10.1039/c2sc20732j

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Bulge-like Asymmetric Heterodye Clustering in DNA Duplex Results in Efficient Quenching of Background Emission Based on the Maximized Excitonic Interaction2012

    • Author(s)
      T. Fujii, Y. Hara, T. Osawa, H. Kashida, X. G. Liang, Y. Yoshida, H. Asanuma
    • Journal Title

      Chemistry - A European Journal

      Volume: 18 Issue: 35 Pages: 10865-10872

    • DOI

      10.1002/chem.201201365

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Quencher-free molecular beacon tethering 7-hydroxycoumarin detects targets through protonation/deprotonation2012

    • Author(s)
      Kashida, H.; Yamaguchi K.; Hara, Y.; Asanuma, H.
    • Journal Title

      Bioorg. Med. Chem.

      Volume: 20 Issue: 14 Pages: 4310-4315

    • DOI

      10.1016/j.bmc.2012.05.052

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Coherent Interactions of Dyes Assembled on DNA (Review)2012

    • Author(s)
      Asanuma, H.; Fujii, T.; Kato, T.; Kashida, H.
    • Journal Title

      J. Photochem. Photobiol. C

      Volume: 13 Issue: 2 Pages: 124-135

    • DOI

      10.1016/j.jphotochemrev.2012.04.002

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Preparation of supramolecular chromophoric assemblies using a DNA duplex2012

    • Author(s)
      Kashida, H.; Asanuma, H.
    • Journal Title

      Phys. Chem. Chem. Phys.

      Volume: 14 Issue: 20 Pages: 7196-7204

    • DOI

      10.1039/c2cp40520b

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Ultrafast photoisomerization and its single-shot pump pulse efficiency of trans-azobenzene derivative : Compound for photosensitive DNA2012

    • Author(s)
      T.Chen, A.Yamaguchi, K.Igarashi, N.Nakagawa, H.Nishioka, H.Asanuma, M.Yamashita
    • Journal Title

      Opt.Commun.

      Volume: 285 Issue: 6 Pages: 1206-1211

    • DOI

      10.1016/j.optcom.2011.10.032

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Photon-fueled DNA nanodevice carrying two different photoswitches2012

    • Author(s)
      H.Nishioka, X.G.Liang, T.Kato, H.Asanuma
    • Journal Title

      Angew.Chem.Int.Ed.

      Volume: 51 Pages: 1165-1168

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Polycation-chaperoned in-stem molecular beacon system2012

    • Author(s)
      H.Asanuma, T.Osawa, H.Kashida, T.Fujii, X.G.Liang, K.Niwa, Y.Yoshida, N.Shimada, A.Maruyama
    • Journal Title

      Chem.Commun.

      Volume: 48 Pages: 1760-1762

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Improvement of RNAi activity and strand-selectivity of RISC formation by modified siRNA involving intercalators near 5'-termini2012

    • Author(s)
      H.Ito, M.Urushihara, X.G.Liang, H.Asanuma
    • Journal Title

      ChemBioChem

      Volume: 13 Pages: 311-315

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Design of an Artificial Functional Nanomaterial with High Recognition Ability2012

    • Author(s)
      X.G.Liang, T.Mochizuki, T.Fujii, H.Kashida, H.Asanuma
    • Journal Title

      Natural Computing

      Volume: (印刷中)(in press)

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Detection of three-base deletion by exciplex formation with perylene derivatives2011

    • Author(s)
      H.Kashida, N.Kondo, K.Sekiguchi, H.Asanuma
    • Journal Title

      Cbem.Commun.

      Volume: 47 Pages: 6404-6406

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Preparation of photoresponsive DNA tethering ortho-methylated azobenzene as a supraphotoswitch2011

    • Author(s)
      H.Asanuma, H.Nishioka, T.Ishikawa, X.G.Liang
    • Journal Title

      Current Protocols in Nucleic Acid Chemistry

      Volume: 46 Issue: 1

    • DOI

      10.1002/0471142700.nc0445s46

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Nick Sealing by T4 DNA Ligase on a Modified DNA Template Tethering a Functional Molecule on D-Threoninol2011

    • Author(s)
      X.G.Liang, K.Fujioka, H.Asanuma
    • Journal Title

      Chem.Eur.J.

      Volume: 17 Pages: 10388-10396

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Femtosecond photoisomerization of azobenzene-derivative binding to DNA2011

    • Author(s)
      T.Chen, K.Igarashi, N.Nakagawa, K.Yamane, T.Fujii, H.Asanuma, M.Yamashita
    • Journal Title

      J.Photochem.Photobiol.A

      Volume: 223 Pages: 119-123

    • NAID

      120003678801

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Cyclohexyl "base pairs" stabilize duplexes and intensify pyrene fluorescence by shielding it from natural base pairs2011

    • Author(s)
      H.Kashida, K.Sekiguchi, N.Higashiyama, T.Kato, H.Asanuma
    • Journal Title

      Org.Biomol.Chem.

      Volume: 9 Pages: 8313-8320

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Control of the Chirality and Helicity of Oligomers of Serinol Nucleic Acid (SNA) by Sequence Design.2011

    • Author(s)
      Kashida, H.; Murayama, K.; Toda, T.; Asanuma, H.
    • Journal Title

      Angew.Chem.Int.Ed.

      Volume: 50 Pages: 1285-1288

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Design of a Functional Nanomaterial with Recognition Ability for Constructing Light-Driven Nanodevices.2011

    • Author(s)
      Liang, X.G.; Mochizuki, T.; Fujii, T.; Kashida, H.; Asanuma, H.
    • Journal Title

      Lecture Note in Computer Science (LNCS)

      Volume: 6518 Pages: 112-122

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Cationic dye-triplet as unique "glue" that can connect full-matched termini of the duplexes.2011

    • Author(s)
      Kashida, H.; Hayashi, T.; Fujii, T.; Asanuma, H.
    • Journal Title

      Chem.Eur.J.

      Volume: 17 Pages: 2614-2622

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Robust and photo-controllable DNA capsules using azobenzenes2010

    • Author(s)
      Tanaka, F.; Mochizuki, T.; Liang, X.G.; Asanuma, H.; Tanaka, S.; Suzuki, K.; Kitamura, S.; Nishikawa, A.; Ui-Tei, K.; Hagiya, M
    • Journal Title

      Nano Lett.

      Volume: 10 Pages: 3560-3565

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] A light-driven DNA nanomachine for efficiently photoswitching RNA digestion2010

    • Author(s)
      Zhou M.G.; Liang, X.G.; Mochizuki, T.; Asanuma, H.
    • Journal Title

      Angew. Chem. Int. Ed.

      Volume: 49 Pages: 2167-2170

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Unexpectedly stable artificial duplex from flexible acyclic threoninol.2010

    • Author(s)
      Asanuma, H.; Toda, T.; Murayama, K.; Liang, X.G.; Kashida, H.
    • Journal Title

      J.Am.Chem.Soc.

      Volume: 132 Pages: 14702-14703

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Construction of photoresponsive RNA for photoswitching RNA hybridization.2010

    • Author(s)
      Ito, H.; Liang, X.G.; Nishioka, H.; Asanuma, H.
    • Journal Title

      Org.Biomol.Chem.

      Volume: 8 Pages: 5519-5524

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Robust and photo-controllable DNA capsules using azobenzenes.2010

    • Author(s)
      Tanaka, F.; Mochizuki, T.; Liang, X.G.; Asanuma.H.;, et al
    • Journal Title

      Nano Lett.

      Volume: 10 Pages: 3560-3565

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Insulator base pairs for lighting-up perylenediimide in a DNA duplex.2010

    • Author(s)
      Kashida, H.; Sekiguchi, K.; Asanuma, H.
    • Journal Title

      Chem.Eur.J.

      Volume: 16 Pages: 11554-11557

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Coherent Quenching of a Fluorophore for the Design of a Highly Sensitive In-Stem Molecular Beacon.2010

    • Author(s)
      Hara, Y.; Fujii, T.Asanuma, H., et al.
    • Journal Title

      Angew.Chem.Int.Ed.

      Volume: 49 Pages: 5502-5506

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Accumulation of fluorophores into DNA duplexes to mimic the properties of quantum dots.2010

    • Author(s)
      Kashida, H.; Sekiguchi, K.; Liang, X.G.; Asanuma, H.
    • Journal Title

      J.Am.Chem.Soc.

      Volume: 132 Pages: 6223-6230

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Molecular imprinting of cyclodextrin to physiologically active oligopeptides in water.2010

    • Author(s)
      Song, S.H.; Asanuma, H.; Komiyama, M., et al.
    • Journal Title

      Supramol.Chem.

      Volume: 22 Pages: 149-155

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] An interstrand-wedged duplex composed of alternating DNA base pairs and covalently attached intercalators2010

    • Author(s)
      X.G.Liang, H.Nishioka, T.Mochizuki, H.Asanuma
    • Journal Title

      J.Mater.Chem. 20

      Pages: 575-581

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effect of the ortho modification of azobenzene on the photoregulatory of ficiency of DNA hybridization and thermal stability of its cis-form2010

    • Author(s)
      H.Nishioka, X.G.Liang, H.Asanuma
    • Journal Title

      Chem.Eur.J. 16

      Pages: 2479-2486

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] An efficient FRET between pyrene and perylene assembled in a DNA duplex and its potential for discriminating single base changes2010

    • Author(s)
      H.Kashida, T.Takatsu, K.Sekiguchi, H.Asanuma
    • Journal Title

      Chem.Eur.J 16

      Pages: 2479-2486

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A light-driven DNA nanomachine for efficiently photoswitching RNA digestion2010

    • Author(s)
      M.G.Zhou, X.G.Liang, T.Mochizuki, H.Asanuma
    • Journal Title

      Angew.Chem.Int.Ed. 49

      Pages: 2167-2170

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Photoregulation of DNA transcription by using photoresponsive T7 promoters and clarification of its mechanism2010

    • Author(s)
      X.G.Liang, R.Wakuta, K.Fujioka, H.Asanuma
    • Journal Title

      FEBS J. 277

      Pages: 1551-1561

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A Supra-Photoswitch Involving Sandwiched DNA Base Pairs and Azobenzenes for Light-Driven Nanostructures and Nanodevices.2009

    • Author(s)
      Liang, X.G.; Mochizuki, T.; Asanuma, H.
    • Journal Title

      Small

      Volume: 5 Pages: 1761-1768

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Efficient energy transfer from pyrene to perylene assembled inside DNA duplex2009

    • Author(s)
      H.Kashida, T.Takatsu, H.Asanuma
    • Journal Title

      Nucleic Acids Symp.Ser. 53

      Pages: 29-30

    • Related Report
      2009 Annual Research Report
  • [Journal Article] Line up base pairs and intercalators one by one in a stable duplex2009

    • Author(s)
      X.G.Liang, T.Mochizuki, H.Nishioka, H.Asanuma
    • Journal Title

      Nucleic Acids Symp.Ser. 53

      Pages: 189-190

    • Related Report
      2009 Annual Research Report
  • [Journal Article] A Supra-Photoswitch Involving Sandwiched DNA Base Pairs and Azobenzenes for Light-Driven Nanostructures and Nanodevices2009

    • Author(s)
      X.G.Liang, T.Mochizuki, H.Asanuma
    • Journal Title

      Small 5

      Pages: 1761-1768

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Photoisomerization dynamics study on cis-azobenzene derivative using ultraviolet-to-visible tunable femtosecond pulses2009

    • Author(s)
      H.Asanuma, M.Yamashita, et al.
    • Journal Title

      Appl.Surf.Sci. 255

      Pages: 9864-9868

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Positively charged base surrogate for highly stable "base-pairing" through electrostatic and stacking interactions2009

    • Author(s)
      H.Kashida, H.Ito, T.Fujii, T.Hayashi, H.Asanuma
    • Journal Title

      J.Am.Chem.Soc. 131

      Pages: 9928-9930

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Analysis of Coherent Heteroclustering of Different Dyes by Use of Threoninol-Nucleotides for Comparison with the Molecular Exciton Theory2009

    • Author(s)
      T.Fujii, H.Kashida, H.Asanuma
    • Journal Title

      Chem.Eur.J. 15

      Pages: 10092-10102

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] In-Stem Molecular Beacon containing a Pseudo Base Pair of Threoninol Nucleotides for Removal of Background Emission2009

    • Author(s)
      H.Asanuma, H.Kashida, et al
    • Journal Title

      Angew.Chem.Int.Ed. 48

      Pages: 7044-7048

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] DNAを切断するはさみ2009

    • Author(s)
      西岡英則, 浅沼浩之
    • Journal Title

      化学 11

      Pages: 70-71

    • Related Report
      2009 Annual Research Report
  • [Journal Article]2009

    • Author(s)
      浅沼浩之, 梁興国
    • Journal Title

      DNAのダイナミックな光制御 (超分子サイエンス&テクノロジー ―基礎からイノベーションまで―"、国武豊喜 監修)(エヌ・ティー・エス)

      Pages: 941-948

    • Related Report
      2009 Annual Research Report
  • [Presentation] DNA nano-engineering for the construction of photon-fuelled molecular-machine with azobenzenes as molecular engine2013

    • Author(s)
      H. Asanuma
    • Organizer
      French-- ‐ Japanese Seminar on "Bioinspired Methods and Applications"
    • Place of Presentation
      Tokyo, Japan (Invited)
    • Related Report
      2012 Final Research Report
  • [Presentation] DNA nano-engineering for the construction of photon-fuelled molecular-machine with azobenzenes as molecular engine2013

    • Author(s)
      Hiroyuki Asanuma
    • Organizer
      France-Japan seminar “Bio-Inspired Methods and Applications”
    • Place of Presentation
      フランス大使館(東京)
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] RNAを検出するリニアプローブの設計と、その細胞内イメージングへの応用2013

    • Author(s)
      赤羽真理子 大澤卓矢 加藤智博 神谷由紀子 樫田啓 浅沼浩之
    • Organizer
      日本化学会第93春季年会
    • Place of Presentation
      立命館大学(草津)
    • Related Report
      2012 Annual Research Report
  • [Presentation] 二重鎖の不安定化を伴わない高感度リニアプローブの設計2013

    • Author(s)
      赤羽真理子・丹羽理恵・大澤卓矢・加藤智博・樫田啓・浅沼浩之
    • Organizer
      日本化学会第93春季年会
    • Place of Presentation
      立命館大学(草津)
    • Related Report
      2012 Annual Research Report
  • [Presentation] 修飾アゾベンゼン導入T7 プロモーターによる遺伝子発現の可視光制御2013

    • Author(s)
      高木 利樹・西岡 秀則・神谷 由紀子・梁 興国・浅沼 浩之
    • Organizer
      日本化学会第93春季年会
    • Place of Presentation
      立命館大学(草津)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Diels-Alder反応を用いたDNA二重鎖間の架橋2013

    • Author(s)
      岡山泰彰、東山尚史、加藤智博、樫田啓、浅沼浩之
    • Organizer
      日本化学会第93春季年会
    • Place of Presentation
      立命館大学(草津)
    • Related Report
      2012 Annual Research Report
  • [Presentation] 非環状骨格を持つ人工核酸の導入によるsiRNAの安定性と活性の向上2013

    • Author(s)
      高井順矢, 村山恵司, 伊藤浩, 樫田啓、神谷由紀子,浅沼浩之
    • Organizer
      日本化学会第93春季年会
    • Place of Presentation
      立命館大学(草津)
    • Related Report
      2012 Annual Research Report
  • [Presentation] 色素対導入siRNAを用いたRISCの細胞内蛍光イメージング2013

    • Author(s)
      神谷由紀子・伊藤杏奈・高井順矢・漆原雅朗・伊藤浩・樫田啓・梁興国・浅沼浩之
    • Organizer
      日本化学会第93春季年会
    • Place of Presentation
      立命館大学(草津)
    • Related Report
      2012 Annual Research Report
  • [Presentation] 非環状ジオールを骨格とする新規人工核酸aTNA及びSNAの開発と、その核酸検出プローブへの応用2013

    • Author(s)
      村山恵司、田中良寛、樫田啓、浅沼浩之
    • Organizer
      日本化学会第93春季年会
    • Place of Presentation
      立命館大学(草津)
    • Related Report
      2012 Annual Research Report
  • [Presentation] p-stilbazole導入RNAによるRNA二重鎖の光架橋2013

    • Author(s)
      土居哲也、飯柴一輝、榊原拓海、高井順矢、神谷由紀子、樫田啓、浅沼浩之
    • Organizer
      日本化学会第93春季年会
    • Place of Presentation
      立命館大学(草津)
    • Related Report
      2012 Annual Research Report
  • [Presentation] DNA二重鎖内部へ付加的に導入された色素間のFRETに関する研究2013

    • Author(s)
      加藤 智博・樫田 啓・岸田 英夫・矢田 祐之・岡本 博・浅沼 浩之
    • Organizer
      日本化学会第93春季年会
    • Place of Presentation
      立命館大学(草津)
    • Related Report
      2012 Annual Research Report
  • [Presentation] スチルベン誘導体の[2+2] 二量化反応を利用したDNA二重鎖の光架橋2013

    • Author(s)
      土居哲也・榊原拓海・林威光・藤井大雅・樫田啓・浅沼浩之
    • Organizer
      日本化学会第93春季年会
    • Place of Presentation
      立命館大学(草津)
    • Related Report
      2012 Annual Research Report
  • [Presentation] 色素クラスター形成を利用した多機能型プローブの設計2012

    • Author(s)
      浅沼浩之
    • Organizer
      共同研究拠点トップダウンプロジェクトミニシンポジウム
    • Place of Presentation
      東北大学(宮城県)(招待講演)
    • Year and Date
      2012-01-16
    • Related Report
      2011 Annual Research Report
  • [Presentation] アゾ系色素による選択的ヘテロ会合体形成を利用したDNA二重鎖の連結2012

    • Author(s)
      土居哲也・林威光・藤井大雅・樫田啓・浅沼浩之
    • Organizer
      第61回高分子学会年次大会
    • Place of Presentation
      パシフィコ横浜(横浜)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Threoninolを用いた新規人工核酸aTNAの安定性の解析2012

    • Author(s)
      田中良寛・村山恵司・樫田啓・浅沼浩之
    • Organizer
      第61回高分子学会年次大会
    • Place of Presentation
      パシフィコ横浜(横浜)
    • Related Report
      2012 Annual Research Report
  • [Presentation] RISCの選択的モニタリングを目指した色素クラスター導入RNA二重鎖の設計2012

    • Author(s)
      漆原雅朗・伊藤浩・梁興国・樫田啓・浅沼浩之
    • Organizer
      第61回高分子学会年次大会
    • Place of Presentation
      パシフィコ横浜(横浜)
    • Related Report
      2012 Annual Research Report
  • [Presentation] 励起子相互作用を利用した高感度モレキュラービーコンの開発2012

    • Author(s)
      樫田 啓・藤井 大雅・原 雄一・吉田 安子・浅沼 浩之
    • Organizer
      2012年光化学討論会
    • Place of Presentation
      東京工業大学(大岡山)
    • Related Report
      2012 Annual Research Report
  • [Presentation] DNA二重鎖内部に固定化した蛍光色素間のエネルギー移動に関する研究2012

    • Author(s)
      加藤 智博・樫田 啓・岸田 英夫・矢田 祐之・岡本 博・浅沼 浩之
    • Organizer
      2012年光化学討論会
    • Place of Presentation
      東京工業大学(大岡山)
    • Related Report
      2012 Annual Research Report
  • [Presentation] DNA二重鎖を利用した色素会合体のらせん制御2012

    • Author(s)
      樫田啓・土居哲也・藤井大雅・浅沼浩之
    • Organizer
      第61回高分子討論会
    • Place of Presentation
      名古屋工業大学(名古屋)
    • Related Report
      2012 Annual Research Report
  • [Presentation] ステム構造が不要なリニア型核酸プローブによるDNA・RNAの高感度検出2012

    • Author(s)
      赤羽真理子・近藤展代・大澤卓矢・加藤智博・樫田啓・浅沼浩之
    • Organizer
      第61回高分子討論会
    • Place of Presentation
      名古屋工業大学(名古屋)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Highly Sensitive Fluorescent Probe designed with Threoninol-Nucleotides2012

    • Author(s)
      Hiroyuki Asanuma
    • Organizer
      A3RONA 2012 KOREA
    • Place of Presentation
      POSTEC(Korea)
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] Photon-fuelled DNA nanomachine carrying azobenzene as molecular engine2012

    • Author(s)
      Hiroyuki Asanuma
    • Organizer
      CIMTECH2012
    • Place of Presentation
      Montecatini Terme(Italy)
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] Development of functional siRNA for activating RNAi and tracing RISC2012

    • Author(s)
      Hiroyuki Asanuma, Hiroshi Ito, Masaaki Urushihara, Xingguo Liang, Hiromu Kashida
    • Organizer
      The Second Asian Chemical Biology Conference (ACBC2012)
    • Place of Presentation
      Okinawa
    • Related Report
      2012 Annual Research Report
  • [Presentation] Functionalization of novel artificial nucleic acids from acyclic diols2012

    • Author(s)
      Keiji Murayama, Yoshihiro Tanaka, Hiromu Kashida and Hiroyuki Asanuma
    • Organizer
      The Second Asian Chemical Biology Conference (ACBC2012)
    • Place of Presentation
      Okinawa
    • Related Report
      2012 Annual Research Report
  • [Presentation] Quencher-free linear probe with multiple fluorophores2012

    • Author(s)
      Mariko AKAHANE, Nobuyo KONDO, Takuya OSAWA, Tomohiro KATO, Hiromu KASHIDA, and Hiroyuki ASANUMA
    • Organizer
      The 39th International Symposium onNucleic Acids Chemistry(ISNAC2012)
    • Place of Presentation
      Nagoya Univ.(Nagoya)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Crosslinking of DNA through photodimerization of stilbene derivatives2012

    • Author(s)
      Tetsuya Doi, Takamitsu Hayashi, Taiga Fujii, Takumi Sakakibara, Hiromu Kashida, Hiroyuki Asanuma
    • Organizer
      The 39th International Symposium onNucleic Acids Chemistry(ISNAC2012)
    • Place of Presentation
      Nagoya Univ.(Nagoya)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Design and development of the functionalized siRNA  for studying RNAi2012

    • Author(s)
      Yukiko Kamiya and Hiroyuki Asanuma, et al.
    • Organizer
      The 39th International Symposium onNucleic Acids Chemistry(ISNAC2012)
    • Place of Presentation
      Nagoya Univ.(Nagoya)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Unusual Fluorescent H-aggregation by Covalent Incorporation of Pseudoisocyanine into DNA Duplex2012

    • Author(s)
      Taiga Fujii, Hiromu Kashida, Yasuyuki Araki, Takehiko Wada, Hiroyuki Asanuma
    • Organizer
      The 39th International Symposium onNucleic Acids Chemistry(ISNAC2012)
    • Place of Presentation
      Nagoya Univ.(Nagoya)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Development of a robust FRET system within DNA duplex using base-surrogate tethering2012

    • Author(s)
      Tomohiro Kato, Hiromu Kashida, Hideo Kishida, Hiroyuki Yada, Hiroshi Okamoto, Hiroyuki Asanuma
    • Organizer
      The 39th International Symposium onNucleic Acids Chemistry(ISNAC2012)
    • Place of Presentation
      Nagoya Univ.(Nagoya)
    • Related Report
      2012 Annual Research Report
  • [Presentation] DNA nano-engineering for the construction of photon-fuelled molecular-machine2012

    • Author(s)
      H. Asanuma, H. Nishioka, X.G. Liang, Y. Kamiya
    • Organizer
      5th NTTH symposium
    • Place of Presentation
      Okinawa
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] インスレーターを用いたTAMRA標識核酸の高輝度化2012

    • Author(s)
      東山 尚史、樫田 啓、浅沼 浩之
    • Organizer
      第6回バイオ関連化学シンポジウム
    • Place of Presentation
      北海道
    • Related Report
      2012 Annual Research Report
  • [Presentation] ステム構造が不要な高感度リニアプローブによるDNA・RNA配列特異的検出2012

    • Author(s)
      赤羽 真理子、近藤 展代、大澤 卓矢、加藤 智博、樫田 啓、浅沼 浩之
    • Organizer
      第6回バイオ関連化学シンポジウム
    • Place of Presentation
      北海道
    • Related Report
      2012 Annual Research Report
  • [Presentation] スチルベン誘導体を利用したDNAの連結および光架橋による固定化2012

    • Author(s)
      土居 哲也・榊原 拓海・林 威光・藤井 大雅・樫田 啓・浅沼 浩之
    • Organizer
      第6回バイオ関連化学シンポジウム
    • Place of Presentation
      北海道
    • Related Report
      2012 Annual Research Report
  • [Presentation] Off-target効果の抑制とRNAi活性の向上を目指した新規修飾siRNAの設計2012

    • Author(s)
      高井順矢・梁興国・伊藤浩・浅沼浩之
    • Organizer
      第6回バイオ関連化学シンポジウム
    • Place of Presentation
      北海道
    • Related Report
      2012 Annual Research Report
  • [Presentation] Diels-Alder反応によるDNA二重鎖間架橋法の開発2012

    • Author(s)
      岡山泰彰・東山尚史・加藤智博・樫田啓・浅沼浩之
    • Organizer
      第6回バイオ関連化学シンポジウム
    • Place of Presentation
      北海道
    • Related Report
      2012 Annual Research Report
  • [Presentation] リン酸アニオンを認識する蛍光性核酸プローブの開発2012

    • Author(s)
      樫田 啓・山口 恭平・佐野 香苗・浅沼 浩之
    • Organizer
      第6回バイオ関連化学シンポジウム
    • Place of Presentation
      北海道
    • Related Report
      2012 Annual Research Report
  • [Presentation] 非環状ジオールD-Threoninolを骨格とした新規人工核酸aTNAの安定性の解析2012

    • Author(s)
      田中 良寛・村山 恵司・神谷 由紀子・樫田 啓・浅沼 浩之
    • Organizer
      第6回バイオ関連化学シンポジウム
    • Place of Presentation
      北海道
    • Related Report
      2012 Annual Research Report
  • [Presentation] 色素対型siRNAを用いたRISC形成過程の可視化解析2012

    • Author(s)
      漆原雅朗・伊藤浩・藤井大雅・梁興国・伊藤杏奈・樫田啓・神谷由紀子・浅沼浩之
    • Organizer
      第6回バイオ関連化学シンポジウム
    • Place of Presentation
      北海道
    • Related Report
      2012 Annual Research Report
  • [Presentation] 非環状骨格を有する人工核酸SNAへの色素導入による機能化2012

    • Author(s)
      村山 恵司・樫田 啓・浅沼 浩之
    • Organizer
      第6回バイオ関連化学シンポジウム
    • Place of Presentation
      北海道
    • Related Report
      2012 Annual Research Report
  • [Presentation] DNA二重鎖内部に導入した蛍光色素間のFRET効率に関する研究2012

    • Author(s)
      加藤 智博・樫田 啓・岸田 英夫・矢田 祐之・岡本 博・浅沼 浩之
    • Organizer
      第6回バイオ関連化学シンポジウム
    • Place of Presentation
      北海道
    • Related Report
      2012 Annual Research Report
  • [Presentation] RNAi活性の向上とOff-target効果の抑制を目指した修飾siRNAの分子設計2012

    • Author(s)
      伊藤 浩、漆原 雅朗、高井順矢、梁興国、浅沼 浩之
    • Organizer
      第14回日本RNA学会年会
    • Place of Presentation
      東北大学(仙台)
    • Related Report
      2012 Annual Research Report
  • [Presentation] 配列選択的RISC形成を目指した新規修飾siRNAの設計2012

    • Author(s)
      高井順矢,梁興国,伊藤浩,神谷由紀子,浅沼浩之
    • Organizer
      アンチセンス・遺伝子・デリバリーシンポジウム2012
    • Place of Presentation
      仙台
    • Related Report
      2012 Annual Research Report
  • [Presentation] ステム構造および消光色素を持たない新規Linear Probe によるDNA・RNAの高感度検出2012

    • Author(s)
      赤羽 真理子・近藤 展代・大澤 卓矢・加藤 智博・樫田 啓・浅沼 浩之
    • Organizer
      第2回CSJ化学フェスタ
    • Place of Presentation
      東京工業大学(大岡山)
    • Related Report
      2012 Annual Research Report
  • [Presentation] New Artificial Nucleic Acids from Acyclic Scaffolds2012

    • Author(s)
      K.Murayama, T.Toda, H.Kashida, H.Asanuma
    • Organizer
      Twelfth International Symposium on Bio-mimetic Materials Processing (BMMP-12)
    • Place of Presentation
      Nagoya, Japan(Invited)
    • Related Report
      2011 Annual Research Report
  • [Presentation] 医療応用を目指した実用的な人工ヌクレオチドの設計2012

    • Author(s)
      浅沼浩之
    • Organizer
      国際医薬品原料・中間体展2012(CPhI Japan 2012)
    • Place of Presentation
      東京ビッグサイト(東京都)(招待講演)
    • Related Report
      2011 Annual Research Report
  • [Presentation] Efficient quenching of the background emission for development of a highly sensitive molecular beacon2012

    • Author(s)
      T.Fujii, H.Kashida, H.Asanuma
    • Organizer
      International Symposium on "Nanobiotechnology meets Holonic Communication
    • Place of Presentation
      Nagoya, Japan
    • Related Report
      2011 Annual Research Report
  • [Presentation] ステム構造を必要としない高感度リニアプローブの設計2012

    • Author(s)
      浅沼浩之・赤羽真理子・近藤展代・大澤卓矢・加藤智博・樫田啓
    • Organizer
      日本化学会第92春季年会
    • Place of Presentation
      慶應義塾大学(神奈川県)
    • Related Report
      2011 Annual Research Report
  • [Presentation] 非環状人工核酸aTNA及びSNAの色素とのコンジュゲーションによる高機能化2012

    • Author(s)
      村山恵司・冨田孝亮・樫田啓・浅沼浩之
    • Organizer
      日本化学会第92春季年会
    • Place of Presentation
      慶應義塾大学(神奈川県)
    • Related Report
      2011 Annual Research Report
  • [Presentation] インスレーターを用いた蛍光標識核酸プローブの高輝度化2012

    • Author(s)
      東山尚史・関口康司・樫田啓・浅沼浩之
    • Organizer
      日本化学会第92春季年会
    • Place of Presentation
      慶應義塾大学(神奈川県)
    • Related Report
      2011 Annual Research Report
  • [Presentation] DNA二重鎖内部における蛍光色素のエネルギー移動に関する研究2012

    • Author(s)
      加藤智博・樫田啓・浅沼浩之
    • Organizer
      日本化学会第92春季年会
    • Place of Presentation
      慶應義塾大学(神奈川県)
    • Related Report
      2011 Annual Research Report
  • [Presentation] ループ部位への可逆的二重鎖形成を利用した新規光応答性DNAzymeの設計2012

    • Author(s)
      加藤憲司郎・梁興国・浅沼浩之
    • Organizer
      日本化学会第92春季年会
    • Place of Presentation
      慶應義塾大学(神奈川県)
    • Related Report
      2011 Annual Research Report
  • [Presentation] siRNAへのインターカレーター導入による選択的RISC形成とそのメカニズム2012

    • Author(s)
      伊藤浩・梁興国・浅沼浩之
    • Organizer
      日本化学会第92春季年会
    • Place of Presentation
      慶應義塾大学(神奈川県)
    • Related Report
      2011 Annual Research Report
  • [Presentation] 非環状骨格を持つ人工核酸を導入したsiRNAのRNA干渉への影響2012

    • Author(s)
      伊藤浩・高井順矢・村山恵司・漆原雅朗・浅沼浩之
    • Organizer
      日本化学会第92春季年会
    • Place of Presentation
      慶應義塾大学(神奈川県)
    • Related Report
      2011 Annual Research Report
  • [Presentation] RISCの選択的蛍光モニタリングを目指した色素対導入siRNAの設計2012

    • Author(s)
      漆原雅朗・伊藤浩・樫田啓・梁興国・浅沼浩之
    • Organizer
      日本化学会第92春季年会
    • Place of Presentation
      慶應義塾大学(神奈川県)
    • Related Report
      2011 Annual Research Report
  • [Presentation] スチルバゾールの二量化反応を利用したDNA二重鎖の光架橋2012

    • Author(s)
      土居哲也・榊原拓海・林威光・藤井大雅・樫田啓・浅沼浩之
    • Organizer
      日本化学会第92春季年会
    • Place of Presentation
      慶應義塾大学(神奈川県)
    • Related Report
      2011 Annual Research Report
  • [Presentation] ストランドインベーダーへの応用を目指した人工ヌクレオチドの設計2011

    • Author(s)
      熊南和哉・梁興国・樫田啓・浅沼浩之
    • Organizer
      日本化学会第91春季年会
    • Place of Presentation
      (要旨集)(口頭)
    • Year and Date
      2011-03-11
    • Related Report
      2010 Annual Research Report
  • [Presentation] siRNAの化学修飾によるRNAi活性の向上2011

    • Author(s)
      伊藤浩・梁興国・浅沼浩之
    • Organizer
      日本化学会第91春季年会
    • Place of Presentation
      (要旨集)(口頭)
    • Year and Date
      2011-03-11
    • Related Report
      2010 Annual Research Report
  • [Presentation] 新規ペリレン誘導体導入DNAプローブを用いた三塩基欠失の検出2011

    • Author(s)
      近藤展代・関口康司・樫田啓・浅沼浩之
    • Organizer
      日本化学会第91春季年会
    • Place of Presentation
      (要旨集)(口頭)
    • Year and Date
      2011-03-11
    • Related Report
      2010 Annual Research Report
  • [Presentation] カチオン性グラフトポリマーとの併用による超高感度インステムモレキュラービーコンシステム2011

    • Author(s)
      浅沼浩之・大澤卓矢・藤井大雅・梁興国・樫田啓・吉田安子・嶋田直彦・丸山厚
    • Organizer
      日本化学会第91春季年会
    • Place of Presentation
      (要旨集)(口頭)
    • Year and Date
      2011-03-11
    • Related Report
      2010 Annual Research Report
  • [Presentation] DNA機能の可視光制御を目指したアゾベンゼン修飾の分子設計2011

    • Author(s)
      石川顕慎・西岡英則・沢邊恭一・梁興国・浅沼浩之
    • Organizer
      日本化学会第91春季年会
    • Place of Presentation
      (要旨集)(口頭)
    • Year and Date
      2011-03-11
    • Related Report
      2010 Annual Research Report
  • [Presentation] 二種類の修飾アゾベンゼンを用いた高度な光駆動型DNAナノデバイスの構築2011

    • Author(s)
      西岡英則・石川顕慎・梁興国・浅沼浩之
    • Organizer
      日本化学会第91春季年会
    • Place of Presentation
      (要旨集)(口頭)
    • Year and Date
      2011-03-11
    • Related Report
      2010 Annual Research Report
  • [Presentation] 光で操作可能なナノデバイスを構築するための光応答性粘着末端の分子設計2011

    • Author(s)
      梁興国・水谷春華・浅沼浩之
    • Organizer
      日本化学会第91春季年会
    • Place of Presentation
      (要旨集)(口頭)
    • Year and Date
      2011-03-11
    • Related Report
      2010 Annual Research Report
  • [Presentation] 蛍光色素の高効率消光を目指した非対称色素クラスター形成2011

    • Author(s)
      藤井大雅・原雄一・大澤卓矢・樫田啓・梁興国・吉田安子・浅沼浩之
    • Organizer
      日本化学会第91春季年会
    • Place of Presentation
      (要旨集)(口頭)
    • Year and Date
      2011-03-11
    • Related Report
      2010 Annual Research Report
  • [Presentation] インスレーター能の向上を目指した人工塩基対の合成2011

    • Author(s)
      関口康司・樫田啓・浅沼浩之
    • Organizer
      日本化学会第91春季年会
    • Place of Presentation
      (要旨集)(口頭)
    • Year and Date
      2011-03-11
    • Related Report
      2010 Annual Research Report
  • [Presentation] 配列設計によるSNA二重鎖のらせん構造制御2011

    • Author(s)
      村山恵司・冨田孝亮・樫田啓・浅沼浩之
    • Organizer
      日本化学会第91春季年会
    • Place of Presentation
      (要旨集)(口頭)
    • Year and Date
      2011-03-11
    • Related Report
      2010 Annual Research Report
  • [Presentation] DNA二重鎖の強固な連結を目指したカチオン性人工塩基対の開発2011

    • Author(s)
      樫田啓・林威光・藤井大雅・浅沼浩之
    • Organizer
      日本化学会第91春季年会
    • Place of Presentation
      (要旨集)(口頭)
    • Year and Date
      2011-03-11
    • Related Report
      2010 Annual Research Report
  • [Presentation] Molecular biology and nanotechnology of azobenzene-modified nucleic acid2011

    • Author(s)
      X.G.Liang
    • Organizer
      G-COE symposium in Nagoya on Biochemistry and Bionanotechnology
    • Place of Presentation
      Nagoya (Japan)(invited)
    • Year and Date
      2011-01-12
    • Related Report
      2010 Annual Research Report
  • [Presentation] Development of Insulator Base Pairs for the Drastic Enhancement of Quantum Yield2011

    • Author(s)
      H.Kashida, K.Sekiguchi, H.Asanuma
    • Organizer
      XVth Symposium on Chemistry of Nucleic Acid Components
    • Place of Presentation
      Cesky Krumlov, Czech Republic
    • Related Report
      2011 Annual Research Report
  • [Presentation] "Old but New Artificial Nucleic Acids from Acyclic Threoninol (aTNA)and Serinol (SNA)2011

    • Author(s)
      H.Kashida, K.Murayama, T.Toda, X.G.Liang, H.Asanuma
    • Organizer
      XVth Symposium on Chemistry of Nucleic Acid Components
    • Place of Presentation
      Cesky Krumlov, Czech Republic(基調講演)(招待講演)
    • Related Report
      2011 Annual Research Report
  • [Presentation] Construction of light-driven DNA-seesaw with two photo-switches of modified azobenzene2011

    • Author(s)
      H.Nishioka, T.Ishikawa, X.G.Liang, H.Asanuma
    • Organizer
      第60回高分子学会年次大会
    • Place of Presentation
      大阪国際会議場(大阪府)
    • Related Report
      2011 Annual Research Report
  • [Presentation] Strong adhesion between full-matched DNA duplexes through "base-pairing" of cationic dyes2011

    • Author(s)
      H.Kashida, T.Hayashi, T.Fujii, H.Asanuma
    • Organizer
      第60回高分子学会年次大会
    • Place of Presentation
      大阪国際会議場(大阪府)
    • Related Report
      2011 Annual Research Report
  • [Presentation] 蛍光色素の高輝度化を目指した新規人工塩基対の開発2011

    • Author(s)
      樫田啓・関口康司・浅沼浩之
    • Organizer
      第21回バイオ・高分子シンポジウム
    • Place of Presentation
      関西大学千里山キャンパス(大阪府)
    • Related Report
      2011 Annual Research Report
  • [Presentation] 非対称色素クラスター形成による蛍光色素の高効率消光2011

    • Author(s)
      藤井大雅・原雄一・大澤卓矢・樫田啓・梁興国・吉田安子・浅沼浩之
    • Organizer
      第21回バイオ・高分子シンポジウム
    • Place of Presentation
      関西大学千里山キャンパス(大阪府)
    • Related Report
      2011 Annual Research Report
  • [Presentation] インステムモレキュラービーコンとカチオン性グラフトポリマーを用いた超高感度プローブの設計2011

    • Author(s)
      大澤卓矢・藤井大雅・梁興国・樫田啓・吉田安子・嶋田直彦・丸山厚・浅沼浩之
    • Organizer
      第21回バイオ・高分子シンポジウム
    • Place of Presentation
      関西大学千里山キャンパス(大阪府)
    • Related Report
      2011 Annual Research Report
  • [Presentation] インスレーターを用いたFITC標識核酸プローブの高輝度化2011

    • Author(s)
      東山尚史・関口康司・樫田啓・浅沼浩之
    • Organizer
      第21回バイオ・高分子シンポジウム
    • Place of Presentation
      関西大学千里山キャンパス(大阪府)
    • Related Report
      2011 Annual Research Report
  • [Presentation] アルキルチオ修飾アゾベンゼンによるDNA二重鎖形成と解離の可視光制御2011

    • Author(s)
      石川顕慎・西岡英則・沢邊恭一・梁興国・浅沼浩之
    • Organizer
      第21回バイオ・高分子シンポジウム
    • Place of Presentation
      関西大学千里山キャンパス(大阪府)
    • Related Report
      2011 Annual Research Report
  • [Presentation] スチルバゾールの光二量化反応を利用したDNAの光架橋2011

    • Author(s)
      樫田啓・林威光・土居哲也・浅沼浩之
    • Organizer
      2011年光化学討論会
    • Place of Presentation
      宮崎市河畔コンベンショネリア(宮崎県)
    • Related Report
      2011 Annual Research Report
  • [Presentation] オルト位修飾によるcis-アゾベンゼンの熱異性化の抑制2011

    • Author(s)
      西岡英則・梁興国・浅沼浩之
    • Organizer
      2011年光化学討論会
    • Place of Presentation
      宮崎市河畔コンベンショネリア(宮崎県)
    • Related Report
      2011 Annual Research Report
  • [Presentation] カチオン性色素会合を利用した光機能性DNAグルーの開発2011

    • Author(s)
      樫田啓・林威光・土居哲也・浅沼浩之
    • Organizer
      第5回バイオ関連化学シンポジウム
    • Place of Presentation
      つくば国際会議場「エポカルつくば」(茨城県)
    • Related Report
      2011 Annual Research Report
  • [Presentation] 修飾dsRNAを用いた選択的RISC形成とRNAi活性の向上2011

    • Author(s)
      伊藤浩・梁興国・浅沼浩之
    • Organizer
      第5回バイオ関連化学シンポジウム
    • Place of Presentation
      つくば国際会議場「エポカルつくば」(茨城県)
    • Related Report
      2011 Annual Research Report
  • [Presentation] DNA骨格を利用したシアニン系新規色素会合体の開発2011

    • Author(s)
      藤井大雅・樫田啓・浅沼浩之
    • Organizer
      第5回バイオ関連化学シンポジウム
    • Place of Presentation
      つくば国際会議場「エポカルつくば」(茨城県)
    • Related Report
      2011 Annual Research Report
  • [Presentation] 非環状骨格を有する人工核酸aTNAとSNAの機能化2011

    • Author(s)
      村山恵司・冨田孝亮・樫田啓・浅沼浩之
    • Organizer
      第5回バイオ関連化学シンポジウム
    • Place of Presentation
      つくば国際会議場「エポカルつくば」(茨城県)
    • Related Report
      2011 Annual Research Report
  • [Presentation] 蛍光色素の高輝度化を目指した新規人工塩基対の開発2011

    • Author(s)
      加藤智博・関口康司・樫田啓・浅沼浩之
    • Organizer
      第5回バイオ関連化学シンポジウム
    • Place of Presentation
      つくば国際会議場「エポカルつくば」(茨城県)
    • Related Report
      2011 Annual Research Report
  • [Presentation] RNA二重鎖中での色素会合体形成を用いたRNAiの細胞内イメージング2011

    • Author(s)
      漆原雅朗・伊藤浩・藤井大雅・樫田啓・梁興国・浅沼浩之
    • Organizer
      第5回バイオ関連化学シンポジウム
    • Place of Presentation
      つくば国際会議場「エポカルつくば」(茨城県)
    • Related Report
      2011 Annual Research Report
  • [Presentation] DNAzymeによるCatalytic loopの構造の光制御を利用したRNA切断の光スィッチング2011

    • Author(s)
      加藤憲司郎・周孟光・梁興国・浅沼浩之
    • Organizer
      第5回バイオ関連化学シンポジウム
    • Place of Presentation
      つくば国際会議場「エポカルつくば」(茨城県)
    • Related Report
      2011 Annual Research Report
  • [Presentation] インスレーターを利用した、高輝度FITC標識核酸プローブの開発2011

    • Author(s)
      東山尚史・関口康司・樫田啓・浅沼浩之
    • Organizer
      第5回バイオ関連化学シンポジウム
    • Place of Presentation
      つくば国際会議場「エポカルつくば」(茨城県)
    • Related Report
      2011 Annual Research Report
  • [Presentation] 色素とのコンジュゲーションによる人工核酸aTNAとSNAの機能化2011

    • Author(s)
      村山恵司・冨田孝亮・樫田啓・浅沼浩之
    • Organizer
      第60回高分子討論会
    • Place of Presentation
      岡山大学津島キャンパス(岡山県)
    • Related Report
      2011 Annual Research Report
  • [Presentation] アゾ系色素による会合体形成を利用したDNA二重鎖の連結2011

    • Author(s)
      土居哲也・林威光・藤井大雅・樫田啓・浅沼浩之
    • Organizer
      第60回高分子討論会
    • Place of Presentation
      岡山大学津島キャンパス(岡山県)
    • Related Report
      2011 Annual Research Report
  • [Presentation] DNA二重鎖形成と解離の可視光制御を目指した逆スイッチ型アゾベンゼン誘導体の分子設計2011

    • Author(s)
      石川顕慎・西岡英則・沢邊恭一・梁興国・浅沼浩之
    • Organizer
      第60回高分子討論会
    • Place of Presentation
      岡山大学津島キャンパス(岡山県)
    • Related Report
      2011 Annual Research Report
  • [Presentation] カチオン性グラフト共重合体を用いたインステムモレキュラービーコンの超高感度化2011

    • Author(s)
      大澤卓矢・藤井大雅・梁興国・樫田啓・吉田安子・嶋田直彦・丸山厚・浅沼浩之
    • Organizer
      第60回高分子討論会
    • Place of Presentation
      岡山大学津島キャンパス(岡山県)
    • Related Report
      2011 Annual Research Report
  • [Presentation] ペリレン誘導体導入による新規三塩基欠失検出DNAプローブの開発2011

    • Author(s)
      近藤展代・関口康司・樫田啓・浅沼浩之
    • Organizer
      第60回高分子討論会
    • Place of Presentation
      岡山大学津島キャンパス(岡山県)
    • Related Report
      2011 Annual Research Report
  • [Presentation] Photon-fuelled nanomachine carrying azobenzene as molecular engine2011

    • Author(s)
      H.Asanuma
    • Organizer
      the second A3RONA 2011
    • Place of Presentation
      China, Wuhan, China(招待講演)
    • Related Report
      2011 Annual Research Report
  • [Presentation] Catalytic loop構造の光制御を利用した新規光応答性DNAzymeの開発2011

    • Author(s)
      加藤憲司郎・周孟光・梁興国・浅沼浩之
    • Organizer
      第42回中部化学関係学協会支部連合秋季大会
    • Place of Presentation
      信州大学工学部(長野県)
    • Related Report
      2011 Annual Research Report
  • [Presentation] カチオン性グラフト共重合体との併用によるインステムモレキュラービーコンの高機能化2011

    • Author(s)
      大澤卓矢・藤井大雅・梁興国・樫田啓・吉田安子・嶋田直彦・丸山厚・浅沼浩之
    • Organizer
      第42回中部化学関係学協会支部連合秋季大会
    • Place of Presentation
      信州大学工学部(長野県)
    • Related Report
      2011 Annual Research Report
  • [Presentation] カチオン性色素会合体形成を利用したDNAの連結2011

    • Author(s)
      土居哲也・林威光・藤井大雅・榊原拓海・樫田啓・浅沼浩之
    • Organizer
      第42回中部化学関係学協会支部連合秋季大会
    • Place of Presentation
      信州大学工学部(長野県)
    • Related Report
      2011 Annual Research Report
  • [Presentation] Enhancement of excitonic interaction by asymmetric hetero dyeclustering in DNA duplexes for the efficient quenching of a fluorophore2011

    • Author(s)
      T.Fujii, Y.Hara, T.Osawa, H.Kashida, X.G.Liang, Y.Yoshida, H.Asanuma
    • Organizer
      The 38th International Symposium on Nucleic Acid Chemistry
    • Place of Presentation
      Sapporo, Japan
    • Related Report
      2011 Annual Research Report
  • [Presentation] New artificial nucleic acids from acyclic diols2011

    • Author(s)
      K.Murayama, T.Toda, H.Kashida, H.Asanuma
    • Organizer
      The 38th International Symposium on Nucleic Acid Chemistry
    • Place of Presentation
      Sapporo, Japan(Poster)
    • Related Report
      2011 Annual Research Report
  • [Presentation] Enhancement of RNAi activity and reduction of non-specific effect using modified siRNA involving an intercalator2011

    • Author(s)
      H.Ito, X.G.Liang, H.Asanuma
    • Organizer
      The 38th International Symposium on Nucleic Acid Chemistry
    • Place of Presentation
      Sapporo, Japan(Poster)
    • Related Report
      2011 Annual Research Report
  • [Presentation] Design of novel artificial base pairs for the enhancement of fluorescence2011

    • Author(s)
      H.Kashida, K.Sekiguchi, T.Kato, H.Asanuma
    • Organizer
      The 38th International Symposium on Nucleic Acid Chemistry
    • Place of Presentation
      Sapporo, Japan(Poster)
    • Related Report
      2011 Annual Research Report
  • [Presentation] Highly sensitive in-stem molecular beacon system chaperoned by a cationic copolymer2011

    • Author(s)
      T.Osawa, T.Fujii, X.G.Liang, H.Kashida, Y.Yoshida, N.Shimada, A.Maruyama, H.Asanuma
    • Organizer
      The 38th International Symposium on Nucleic Acid Chemistry
    • Place of Presentation
      Sapporo, Japan(Poster)
    • Related Report
      2011 Annual Research Report
  • [Presentation] "Photocrosslinking of DNA through photodimerization of p -methylstilbazole2011

    • Author(s)
      T.Doi, T.Hayashi, T.Fujii, T.Sakakibara, H.Kashida, H.Asanuma
    • Organizer
      The 38th International Symposium on Nucleic Acid Chemistry
    • Place of Presentation
      Sapporo, Japan(Poster)
    • Related Report
      2011 Annual Research Report
  • [Presentation] Light-up of DNA with artificial nucleotides2011

    • Author(s)
      H.Kashida, K.Sekiguchi, H.Asanuma
    • Organizer
      BMMP-11
    • Place of Presentation
      Nagoya, Japan(invited)
    • Related Report
      2010 Annual Research Report
  • [Presentation] 非天然リンカーを用いた人工核酸の開発 (1) Threoninol を骨格とする機能性核酸の創成2010

    • Author(s)
      冨田孝亮・樫田啓・梁興国・浅沼浩之
    • Organizer
      日本化学会第90春季年会
    • Place of Presentation
      大阪近畿大学
    • Year and Date
      2010-03-26
    • Related Report
      2009 Annual Research Report
  • [Presentation] Rational Design of photoresponsive DNA with cartridge-type nucleotide2010

    • Author(s)
      H. Asanuma
    • Organizer
      International Symposium on Polymer Chemistry (PC 2010)
    • Place of Presentation
      Suzhou, China.(Invited)
    • Related Report
      2012 Final Research Report
  • [Presentation] Azobenzene-tethered DNA for the photoregulation of DNA functions2010

    • Author(s)
      H. Asanuma
    • Organizer
      International Roundtable on Nucleosides, Nucleotides and Nucleic Acids
    • Place of Presentation
      Lyon, France.(Invited).
    • Related Report
      2012 Final Research Report
  • [Presentation] Rational Design of photoresponsive DNA with cartridge-type nucleotide2010

    • Author(s)
      H.Asanuma(invited)
    • Organizer
      International Symposium on Polymer Chemistry (PC 2010)
    • Place of Presentation
      Suzhou, China
    • Related Report
      2010 Annual Research Report
  • [Presentation] Azobenzene-tethered DNA for the photoregulation of DNA functions2010

    • Author(s)
      H.Asanuma(invited)
    • Organizer
      International Roundtable on Nucleosides, Nucleotides and Nucleic Acids(IRT2010)
    • Place of Presentation
      Lyon, France
    • Related Report
      2010 Annual Research Report
  • [Presentation] Light-up of DNA with Threoninol-Nucleotide2010

    • Author(s)
      H.Asanuma(invited)
    • Organizer
      Asian 3 Roundtable on Nucleic Acids (A3RONA 2010 Japan)
    • Place of Presentation
      Osaka, Japan Kansai International Airport Conference Hall(invited)
    • Related Report
      2010 Annual Research Report
  • [Presentation] Creation of highly sensitive in-stem molecular beacon with threoninol-nucleotides2010

    • Author(s)
      H.Asanuma, T.Takatsu, T.Fujii, et al.
    • Organizer
      Pacifichem 2010
    • Place of Presentation
      Hawaii, USA
    • Related Report
      2010 Annual Research Report
  • [Presentation] On-off photoswitching of DNA function with azobenzene-tethered DNA2010

    • Author(s)
      H.Asanuma, H.Nishioka, T.Mochizuki, X.G.Liang
    • Organizer
      Pacifichem 2010
    • Place of Presentation
      Hawaii, USA(invited)
    • Related Report
      2010 Annual Research Report
  • [Presentation] Construction of Photoresponsive Nanodevices by Using a Novel Nanomaterial Involving Multiple Azobenzenes.2010

    • Author(s)
      X.G.Liang, M.G.Zhou, T.Mochizuki, H.Asanuma
    • Organizer
      The 37^<th> International Symposium on Nucleic Acids Chemistry 2010
    • Place of Presentation
      Yokohama(oral)
    • Related Report
      2010 Annual Research Report
  • [Presentation] Synthesis of novel artificial nucleic acid by using chiral serinol as a linker2010

    • Author(s)
      H.Kashida, K.Murayama, T.Toda, H.Asanuma
    • Organizer
      The 37^<th> International Symposium on Nucleic Acids Chemistry 2010
    • Place of Presentation
      Yokohama.
    • Related Report
      2010 Annual Research Report
  • [Presentation] In Stem Molecular Beacon (IS-MB): A Novel Molecular Beacon with Low Background Emission2010

    • Author(s)
      H.Kashida, T.Takatsu, T.Fujii, K.Sekiguchi, X.G.Liang, Y.Yoshida, H.Asanuma
    • Organizer
      International Roundtable on Nucleosides, Nucleotides and Nucleic Acids, 2010
    • Place of Presentation
      Lyon, France(poster)
    • Related Report
      2010 Annual Research Report
  • [Presentation] Nanotechnology of azobenzene-modified DNA for constructing photoresponsive nanostructures and nanodevices2010

    • Author(s)
      X.Liang ; T.Mochizuki ; H.Nishioka ; H.Asanuma
    • Organizer
      PACIFICHEM2010
    • Place of Presentation
      Honolulu, USA.(oral)
    • Related Report
      2010 Annual Research Report
  • [Presentation] Unexpected non-specific DNA synthesis by thermophilic DNA polymerase2010

    • Author(s)
      T.Kato ; X.Liang ; H.Asanuma
    • Organizer
      PACIFICHEM 2010
    • Place of Presentation
      Honolulu, USA(oral)
    • Related Report
      2010 Annual Research Report
  • [Presentation] DNA dot : Accumulation of fluorophores in DNA duplex for the enhancement of emission2010

    • Author(s)
      H.Kashida ; K.Sekiguchi ; H.Asanuma
    • Organizer
      PACIFICHEM 2010
    • Place of Presentation
      Honolulu, USA(oral)
    • Related Report
      2010 Annual Research Report
  • [Presentation] Base pairing of cationic dyes for the stabilization of DNA duplex2010

    • Author(s)
      H.Kashida ; T.Hayashi ; T.Fujii ; H.Asanuma
    • Organizer
      PACIFICHEM 2010
    • Place of Presentation
      Honolulu, USA(poster)
    • Related Report
      2010 Annual Research Report
  • [Presentation] Coherent heteroclustering by using DNA as a scaffold for highly sensitive In-Stem Molecular Beacon.2010

    • Author(s)
      T.Fujii ; Y.Hara ; H.Kashida ; X.Liang ; Y.Yoshida ; H.Asanuma
    • Organizer
      PACIFICHEM 2010
    • Place of Presentation
      Honolulu, USA(poster)
    • Related Report
      2010 Annual Research Report
  • [Presentation] Reversible photoswitching of gene expression with azobenene-modified DNA2010

    • Author(s)
      X.Liang ; K.Fujioka ; R.Wakuda ; H.Asanuma
    • Organizer
      PACIFICHEM 2010
    • Place of Presentation
      Honolulu, USA(oral)
    • Related Report
      2010 Annual Research Report
  • [Presentation] Photoswitching of RNA function by using azobenzene-modified RNA2010

    • Author(s)
      H.Itoh ; X.Liang ; H.Asanuma
    • Organizer
      PACIFICHEM 2010
    • Place of Presentation
      Honolulu, USA(oral)
    • Related Report
      2010 Annual Research Report
  • [Presentation] カチオン性色素クラスター形成によるDNA二重鎖の連結(口頭)2010

    • Author(s)
      樫田啓・林威光・藤井大雅・浅沼浩之
    • Organizer
      第20回バイオ・高分子シンポジウム
    • Place of Presentation
      東京大学
    • Related Report
      2010 Annual Research Report
  • [Presentation] RCA法を活用したターゲットDNAの特異的増幅2010

    • Author(s)
      鈴木晶友・加藤智博・梁興国・浅沼浩之
    • Organizer
      第20回バイオ・高分子シンポジウム
    • Place of Presentation
      東京大学(ポスター)
    • Related Report
      2010 Annual Research Report
  • [Presentation] Serinolを用いた新規人工核酸のキラリティ制御2010

    • Author(s)
      村山恵司・冨田孝亮・樫田啓・浅沼浩之
    • Organizer
      第20回バイオ・高分子シンポジウム
    • Place of Presentation
      東京大学(ポスター)
    • Related Report
      2010 Annual Research Report
  • [Presentation] インスレーター塩基対を用いた蛍光色素のライトアップ2010

    • Author(s)
      関口康司・樫田啓・浅沼浩之
    • Organizer
      第20回バイオ・高分子シンポジウム
    • Place of Presentation
      東京大学(ポスター)
    • Related Report
      2010 Annual Research Report
  • [Presentation] 好熱性DNAポリメラーゼによる異常なDNA合成2010

    • Author(s)
      梁興国・加藤智博・浅沼浩之
    • Organizer
      第20回バイオ・高分子シンポジウム
    • Place of Presentation
      東京大学(口頭)
    • Related Report
      2010 Annual Research Report
  • [Presentation] 蛍光色素の高輝度化を目指したインスレーター塩基対の開発2010

    • Author(s)
      樫田啓・関口康司・浅沼浩之
    • Organizer
      第4回バイオ関連化学シンポジウム
    • Place of Presentation
      大阪大学(口頭)
    • Related Report
      2010 Annual Research Report
  • [Presentation] 新規機能性ナノ材料による光駆動型ナノデバイスの構築2010

    • Author(s)
      梁興国・周孟光・望月敏夫・浅沼浩之
    • Organizer
      第4回バイオ関連化学シンポジウム
    • Place of Presentation
      大阪大学(ポスター)
    • Related Report
      2010 Annual Research Report
  • [Presentation] 超好熱性DNAポリメラーゼによるde novo DNA合成とその機構解明2010

    • Author(s)
      加藤智博・梁興国・浅沼浩之
    • Organizer
      第4回バイオ関連化学シンポジウム
    • Place of Presentation
      大阪大学(ポスター)
    • Related Report
      2010 Annual Research Report
  • [Presentation] "インスレーター塩基対"を用いた高輝度ラベル化法の開発2010

    • Author(s)
      関口康司・樫田啓・浅沼浩之
    • Organizer
      第4回バイオ関連化学シンポジウム
    • Place of Presentation
      大阪大学(ポスター)
    • Related Report
      2010 Annual Research Report
  • [Presentation] 分子間色素クラスター形成を利用したDNAグルーの開発2010

    • Author(s)
      林威光・樫田啓・藤井大雅・浅沼浩之
    • Organizer
      第4回バイオ関連化学シンポジウム
    • Place of Presentation
      大阪大学(ポスター)
    • Related Report
      2010 Annual Research Report
  • [Presentation] Threoninolを骨格に用いた新たな人工ヌクレオチド"aTNA"の二重鎖形成能力の評価2010

    • Author(s)
      冨田孝亮・樫田啓・梁興国・浅沼浩之
    • Organizer
      第4回バイオ関連化学シンポジウム
    • Place of Presentation
      大阪大学(ポスター)
    • Related Report
      2010 Annual Research Report
  • [Presentation] プローブの更なる高感度化を目指した非対称色素クラスターの設計2010

    • Author(s)
      藤井大雅・原雄一・樫田啓・梁興国・吉田安子・浅沼浩之
    • Organizer
      第4回バイオ関連化学シンポジウム
    • Place of Presentation
      大阪大学(ポスター)
    • Related Report
      2010 Annual Research Report
  • [Presentation] 修飾DNAの機能向上を目指した新規機能性分子導入法の開発2010

    • Author(s)
      園田峻・梁興国・樫田啓・浅沼浩之
    • Organizer
      第4回バイオ関連化学シンポジウム
    • Place of Presentation
      大阪大学(ポスター)
    • Related Report
      2010 Annual Research Report
  • [Presentation] RNA scaffoldを利用した色素会合体の調製2010

    • Author(s)
      漆原雅朗・藤井大雅・樫田啓・浅沼浩之
    • Organizer
      第4回バイオ関連化学シンポジウム
    • Place of Presentation
      大阪大学(ポスター)
    • Related Report
      2010 Annual Research Report
  • [Presentation] 非天然リンカーを用いた新規人工核酸の配列設計によるキラリティ制御2010

    • Author(s)
      村山恵司・冨田孝亮・樫田啓・浅沼浩之
    • Organizer
      第4回バイオ関連化学シンポジウム
    • Place of Presentation
      大阪大学(ポスター)
    • Related Report
      2010 Annual Research Report
  • [Presentation] 新規ペリレン誘導体導入による三塩基欠失検出DNAプローブの開発2010

    • Author(s)
      近藤展代・関口康司・樫田啓・浅沼浩之
    • Organizer
      第4回バイオ関連化学シンポジウム
    • Place of Presentation
      大阪大学(ポスター)
    • Related Report
      2010 Annual Research Report
  • [Presentation] アルキルチオアゾベンゼンによるDNA二重鎖形成と解離の可視光制御2010

    • Author(s)
      石川顕慎・西岡英則・沢邊恭一・梁興国・浅沼浩之
    • Organizer
      第4回バイオ関連化学シンポジウム
    • Place of Presentation
      大阪大学(ポスター)
    • Related Report
      2010 Annual Research Report
  • [Presentation] PNAとThreoninol修飾DNAを用いた新規ストランドインベーダーの開発2010

    • Author(s)
      熊南和哉・原雄一・梁興国・樫田啓・浅沼浩之
    • Organizer
      第4回バイオ関連化学シンポジウム
    • Place of Presentation
      大阪大学(ポスター)
    • Related Report
      2010 Annual Research Report
  • [Presentation] Serinol核酸の配列設計による二重らせんのキラリティ制御2010

    • Author(s)
      村山恵司・冨田孝亮・樫田啓・浅沼浩之
    • Organizer
      第59回高分子討論会
    • Place of Presentation
      北海道大学(口頭)
    • Related Report
      2010 Annual Research Report
  • [Presentation] "インスレーター塩基対"を用いた蛍光色素の高輝度化2010

    • Author(s)
      関口康司・樫田啓・浅沼浩之
    • Organizer
      第59回高分子討論会
    • Place of Presentation
      北海道大学(口頭)
    • Related Report
      2010 Annual Research Report
  • [Presentation] 非対称色素クラスターを利用した高感度In-Stem Molecular Beaconの開発2010

    • Author(s)
      藤井大雅・原雄一・吉田安子・梁興国・樫田啓・浅沼浩之
    • Organizer
      第59回高分子討論会
    • Place of Presentation
      北海道大学(口頭)
    • Related Report
      2010 Annual Research Report
  • [Presentation] カチオン性色素会合体形成を利用したDNAワイヤーの調製(口頭)2010

    • Author(s)
      林威光・樫田啓・藤井大雅・浅沼浩之
    • Organizer
      第59回高分子討論会
    • Place of Presentation
      北海道大学
    • Related Report
      2010 Annual Research Report
  • [Presentation] 可視光によるDNA機能の可逆的な光スイッチングを目指したアゾベンゼン誘導体の分子設計2010

    • Author(s)
      西岡英則・梁興国・浅沼浩之
    • Organizer
      第59回高分子討論会
    • Place of Presentation
      北海道大学(口頭)
    • Related Report
      2010 Annual Research Report
  • [Presentation] Serinolを用いた新規人工核酸の開発2010

    • Author(s)
      村山恵司・冨田孝亮・樫田啓・浅沼浩之
    • Organizer
      第41回中部化学関係学協会支部連合協議会
    • Place of Presentation
      豊橋技術科学大学(口頭)
    • Related Report
      2010 Annual Research Report
  • [Presentation] Hetero-clustering in DNA for the design of highly sensitive in -stem molecular beacon2010

    • Author(s)
      浅沼浩之・梁興国, 他
    • Organizer
      BMMP-10
    • Place of Presentation
      Nagoya 名古屋大学
    • Related Report
      2009 Annual Research Report
  • [Presentation] siRNAのアゾベンゼン修飾によるRNA干渉への影響2010

    • Author(s)
      伊藤浩・西岡英則・梁興国・浅沼浩之
    • Organizer
      第12回生命化学研究会
    • Place of Presentation
      福井 芦原温泉清風荘
    • Related Report
      2009 Annual Research Report
  • [Presentation] 高感度蛍光ラベル化剤開発に向けた“インスレーター塩基対"の設計2010

    • Author(s)
      樫田啓・関口康司・浅沼浩之
    • Organizer
      日本化学会第90春季年会
    • Place of Presentation
      大阪近畿大学
    • Related Report
      2009 Annual Research Report
  • [Presentation] オルト位メチル修飾によるシス体アゾベンゼンの熱安定性の向上およびその機構解明2010

    • Author(s)
      西岡英則・梁興国・浅沼浩之
    • Organizer
      日本化学会第90回春季年会
    • Place of Presentation
      大阪近畿大学
    • Related Report
      2009 Annual Research Report
  • [Presentation] アゾベンゼン修飾DNAエンザイムによるRNA切断の光制御2010

    • Author(s)
      周孟光・梁興国・浅沼浩之
    • Organizer
      日本化学会第90春季年会
    • Place of Presentation
      大阪近畿大学
    • Related Report
      2009 Annual Research Report
  • [Presentation] Threoninol nucleotide を用いた非対称色素クラスターの構築2010

    • Author(s)
      藤井大雅・樫田啓・浅沼浩之
    • Organizer
      日本化学会第90春季年会
    • Place of Presentation
      大阪近畿大学
    • Related Report
      2009 Annual Research Report
  • [Presentation] 好熱性DNAポリメラーゼによる鋳型非存在下での短鎖ssDNAの伸長反応とそのメカニズム2010

    • Author(s)
      加藤智博・梁興国・浅沼浩之
    • Organizer
      日本化学会第90春季年会
    • Place of Presentation
      大阪近畿大学
    • Related Report
      2009 Annual Research Report
  • [Presentation] ターゲットDNAの環状化とRCAによるDNAの特異増幅2010

    • Author(s)
      鈴木晶友・加藤智博・梁興国・浅沼浩之
    • Organizer
      日本化学会第90春季年会
    • Place of Presentation
      大阪近畿大学
    • Related Report
      2009 Annual Research Report
  • [Presentation] 蛍光色素の量子収率向上を目指した“インスレーター塩基対"の開発 (2)~核酸塩基からの電子移動抑制によるペリレンジイミドの発光増大~2010

    • Author(s)
      関口康司・樫田啓・浅沼浩之
    • Organizer
      日本化学会第90回春季年会
    • Place of Presentation
      大阪近畿大学
    • Related Report
      2009 Annual Research Report
  • [Presentation] 修飾DNAの機能向上を目指した機能性分子導入リンカーの分子設計2010

    • Author(s)
      園田峻・梁興国・浅沼浩之
    • Organizer
      日本化学会第90春季年会
    • Place of Presentation
      大阪近畿大学
    • Related Report
      2009 Annual Research Report
  • [Presentation] カチオン性擬似塩基対を利用したDNAグルーの開発2010

    • Author(s)
      林威光・藤井大雅・樫田啓・浅沼浩之
    • Organizer
      日本化学会第90回春季年会
    • Place of Presentation
      大阪近畿大学
    • Related Report
      2009 Annual Research Report
  • [Presentation] 遺伝子発現の光制御を目指した光応答性DNAの開発2009

    • Author(s)
      浅沼浩之
    • Organizer
      第30回レーザー医学会総会
    • Place of Presentation
      東京ホテルグウンドヒル市ケ谷
    • Year and Date
      2009-12-02
    • Related Report
      2009 Annual Research Report
  • [Presentation] Efficient energy transfer from pyrene to perylene assembled inside DNA duplex2009

    • Author(s)
      樫田啓・高津智彦・浅沼浩之
    • Organizer
      The 6^<th> International Symposium on Nucleic Acids Chemistry, 2009
    • Place of Presentation
      Takayama, Japan 高山コンベンションホール
    • Year and Date
      2009-09-28
    • Related Report
      2009 Annual Research Report
  • [Presentation] Threoninol-nucleotides によるDNAの再インストール2009

    • Author(s)
      浅沼浩之
    • Organizer
      第58回高分子討論会
    • Place of Presentation
      熊本大学
    • Year and Date
      2009-09-18
    • Related Report
      2009 Annual Research Report
  • [Presentation] Threoninol を骨格とする新規人工核酸の合成2009

    • Author(s)
      冨田孝亮・樫田啓・梁興国・浅沼浩之
    • Organizer
      生体機能関連 (24回)・バイオテクノロジー (12回) シンポジウム
    • Place of Presentation
      福岡 九州大学
    • Year and Date
      2009-09-14
    • Related Report
      2009 Annual Research Report
  • [Presentation] Efficient Photo-Regulation of DNA Hybridization for Constructing Light-driven Nano Device2009

    • Author(s)
      西岡英則・梁興国・浅沼浩之
    • Organizer
      Nagoya University Global COE in Chemistry Annual Symposium
    • Place of Presentation
      Nagoya 名古屋大学
    • Year and Date
      2009-06-09
    • Related Report
      2009 Annual Research Report
  • [Presentation] Heteroclustering of different dyes by DNA hybridization for comparison with the molecular exciton theory2009

    • Author(s)
      藤井大雅・樫田啓・浅沼浩之
    • Organizer
      Nagoya University, Global COE in Chemistry, Establishment of COE for Elucidation and Design of Materials and Molecular Functions
    • Place of Presentation
      Nagoya 名古屋大学
    • Year and Date
      2009-06-09
    • Related Report
      2009 Annual Research Report
  • [Presentation] Application of azobenzene-modified RNA for photoregulation of RNA interference2009

    • Author(s)
      伊藤浩・西岡英則・梁興国・浅沼浩之
    • Organizer
      Nagoya University Global COE in Chemistry "Establishment of COE for Elucidation and Design of Materials and Molecular Functions" 2nd Annual Symposium
    • Place of Presentation
      Nagoya 名古屋大学
    • Year and Date
      2009-06-09
    • Related Report
      2009 Annual Research Report
  • [Presentation] 光機能性インテリジェントDNAの設計と応用2009

    • Author(s)
      浅沼浩之
    • Organizer
      第29回PST-net例会
    • Place of Presentation
      東京学院
    • Year and Date
      2009-04-17
    • Related Report
      2009 Annual Research Report
  • [Presentation] Distinct Stabilization of DNA Duplex by Introducing Cationic Dye Cluster2009

    • Author(s)
      樫田啓・伊藤浩・藤井大雅・浅沼浩之
    • Organizer
      International Conference on Materials for Advanced Technologies 2009 (ICMAT 2009)
    • Place of Presentation
      Singapore
    • Related Report
      2009 Annual Research Report
  • [Presentation] Photo-driven DNA Nanomachine with New Duplex Motif Composed of Threoninol2009

    • Author(s)
      浅沼浩之
    • Organizer
      International Conference on Materials for Advanced Technologies 2009 ICMAT 2009
    • Place of Presentation
      Singapore
    • Related Report
      2009 Annual Research Report
  • [Presentation] De novo DNA synthesis by thermophilic DNA polymerase2009

    • Author(s)
      梁興国・加藤智博・浅沼浩之
    • Organizer
      The 10^<th> International Conference on Thermophiles Research, O17 (pp55)
    • Place of Presentation
      Beiging, China
    • Related Report
      2009 Annual Research Report
  • [Presentation] Rational design of functional DNA with threoninol-nucleotides2009

    • Author(s)
      浅沼浩之
    • Organizer
      Functional Nucleic Acids
    • Place of Presentation
      Germany レーゲンスブルプ
    • Related Report
      2009 Annual Research Report
  • [Presentation] A challenge on specific DNA amplification at ambient temperatures2009

    • Author(s)
      梁興国・鈴木晶友・加藤智博・浅沼浩之
    • Organizer
      The 3^<th> World Congress of Gene (WCG-2009)
    • Place of Presentation
      Foshan、China
    • Related Report
      2009 Annual Research Report
  • [Presentation] Design of in-stem molecular beacon (ISMB) with "threoninol-nucleotide" for the discrimination of polymorphisms2009

    • Author(s)
      浅沼浩之・梁興国, 他
    • Organizer
      The 3^<th> World Congress of Gene (WCG-2009)
    • Place of Presentation
      Foshan, China
    • Related Report
      2009 Annual Research Report
  • [Presentation] Preparation of homo- and hetero-dye cluster by using DNA as a scaffold2009

    • Author(s)
      藤井大雅・樫田啓・浅沼浩之
    • Organizer
      5^<th> International Symposium on Materials for Advanced Technologies (ICMAT 2009) & International Union of Materials Research Societies-International Conference in Asia 2009 (IUMRS-ICA 2009)
    • Place of Presentation
      Singapore
    • Related Report
      2009 Annual Research Report
  • [Presentation] Line up base pairs and intercalators one by one in a stable duplex2009

    • Author(s)
      梁興国・望月敏夫・西岡英則・浅沼浩之
    • Organizer
      6^<th> International Symposium on Nucleic Acids Chemistry
    • Place of Presentation
      Takayama, Japan
    • Related Report
      2009 Annual Research Report
  • [Presentation] Photoresponsive DNA Involving Multiple Azobenzenes Modified with Methyl Group towards the Efficient Photoregulation of DNA Hybridization2009

    • Author(s)
      西岡英則・梁興国・浅沼浩之
    • Organizer
      The 1st FAPS Polymer Congress
    • Place of Presentation
      Nagoya Japan 名古屋国際会議場
    • Related Report
      2009 Annual Research Report
  • [Presentation] Reconstruction of DNAzyme for efficient RNA cleavage at Pyrimidine-Pyrimidine site2009

    • Author(s)
      周孟光・林寛之・梁興国・浅沼浩之
    • Organizer
      The 1st FAPS Polymer Congress
    • Place of Presentation
      Nagoya Japan 名古屋国際会議場
    • Related Report
      2009 Annual Research Report
  • [Presentation] Efficient Photoregulation of DNA Hybridization by Introducing Multiple Modified Azobenzenes2009

    • Author(s)
      西岡英則・梁興国・浅沼浩之
    • Organizer
      3rd NU-UM Joint Symposium on Supramacromolecular Material Science and Engineering in the 21st Century
    • Place of Presentation
      Nagoya, Japan (名古屋大学)
    • Related Report
      2009 Annual Research Report
  • [Presentation] Coherent heteroclustering of different dyes by using DNA as a scaffold2009

    • Author(s)
      藤井大雅・樫田啓・浅沼浩之
    • Organizer
      3^<rd> NU-UM Joint Symposium on Supramacromolecular Material Science and Engineering in the 21^<st> Century
    • Place of Presentation
      Nagoya, Japan 名古屋大学
    • Related Report
      2009 Annual Research Report
  • [Presentation] The influence of siRNA modification with azobenzene for RNA interference2009

    • Author(s)
      伊藤浩・西岡英則・梁興国・浅沼浩之
    • Organizer
      3rd NU-UM Joint Symposium on Supramacromolecular Material Science and Engineering in the 21st Century
    • Place of Presentation
      Nagoya, Japan 名古屋大学
    • Related Report
      2009 Annual Research Report
  • [Presentation] Enhancement of the Activity of DNAzyme 10-23 on Cleaving Pyrimidine-Pyrimidine RNA Site by Covalentlyattaching an Intercalator2009

    • Author(s)
      周孟光・林寛之・梁興国・浅沼浩之
    • Organizer
      WCG-2009
    • Place of Presentation
      Foshan, China
    • Related Report
      2009 Annual Research Report
  • [Presentation] ヒト細胞におけるアゾベンゼン修飾siRNAのRNA干渉効果2009

    • Author(s)
      伊藤浩・西岡英則・梁興国・浅沼浩之
    • Organizer
      第11回RNAミーティング
    • Place of Presentation
      新潟トキナッセ新潟コンベンションセニター
    • Related Report
      2009 Annual Research Report
  • [Presentation] DNA内部での蛍光色素会合を利用した高感度ラベル化法の開発2009

    • Author(s)
      樫田啓・関口康司・高津智彦・浅沼浩之
    • Organizer
      第19回バイオ・高分子シンポジウム
    • Place of Presentation
      東京大学
    • Related Report
      2009 Annual Research Report
  • [Presentation] 光応答性T7プロモーターを用いた遺伝子発現の光制御 ―可視光照射によるGFPタンパク質生成の光スイッチング―2009

    • Author(s)
      梁興国・藤岡健太・和久田竜史・浅沼浩之
    • Organizer
      第19回バイオ・高分子シンポジウム
    • Place of Presentation
      東京大学先端研、東京
    • Related Report
      2009 Annual Research Report
  • [Presentation] Threoninol nucleotide によるヘテロ会合を利用した新規モレキュラービーコンの設計2009

    • Author(s)
      藤井大雅・梁興国・浅沼浩之, 他
    • Organizer
      第19回バイオ・高分子シンポジウム
    • Place of Presentation
      東京大学
    • Related Report
      2009 Annual Research Report
  • [Presentation] 好熱性DNAポリメラーゼによる de novo DNA合成のメカニズム解明2009

    • Author(s)
      加藤智博・梁興国・浅沼浩之
    • Organizer
      第19回バイオ・高分子シンポジウム
    • Place of Presentation
      東京大学
    • Related Report
      2009 Annual Research Report
  • [Presentation] アゾベンゼン導入DNAのナノテクノロジー2009

    • Author(s)
      梁興国・浅沼浩之, 他
    • Organizer
      第24回生体機能関連化学シンポジウム
    • Place of Presentation
      九州大学、福岡
    • Related Report
      2009 Annual Research Report
  • [Presentation] ペリレンーアントラキノン塩基対を利用した高感度 In-Stem Molecular Beacon の開発2009

    • Author(s)
      樫田啓・梁興国・浅沼浩之, 他
    • Organizer
      第24回生体機能関連化学シンポジウム
    • Place of Presentation
      福岡 九州大学
    • Related Report
      2009 Annual Research Report
  • [Presentation] 化学修飾DNAzyme10-23によるRNAの Pyrimidine-Pyrimidine サイトの高効率切断2009

    • Author(s)
      周孟光・林寛之・梁興国・浅沼浩之
    • Organizer
      第24回生体機能関連化学シンポジウム, 第12回バイオテクノロジー部会シンポジウム
    • Place of Presentation
      福岡 九州大学
    • Related Report
      2009 Annual Research Report
  • [Presentation] ヒト細胞内における遺伝子発現の光制御システムの構築2009

    • Author(s)
      伊藤浩・西岡英則・梁興国・浅沼浩之
    • Organizer
      第24回生体機能関連化学シンポジウム・第12回バイオテクノロジー部会シンポジウム
    • Place of Presentation
      福岡 九州大学
    • Related Report
      2009 Annual Research Report
  • [Presentation] 励起子相互作用による消光を利用した新規 Molecular Beacon の設計2009

    • Author(s)
      原雄一・梁興国・浅沼浩之, 他
    • Organizer
      第24回生体機能関連化学シンポジウム、第12回バイオテクノロジー部会シンポジウム
    • Place of Presentation
      福岡 九州大学
    • Related Report
      2009 Annual Research Report
  • [Presentation] 超好熱性DNAポリメラーゼによる短鎖ssDNAの高効率な伸長反応2009

    • Author(s)
      加藤智博・梁興国・浅沼浩之
    • Organizer
      生体機能関連 (24回)・バイオテクノロジー (12回)シンポジウム
    • Place of Presentation
      福岡 九州大学
    • Related Report
      2009 Annual Research Report
  • [Presentation] 可視光による遺伝子発現の光スイッチシグシステムの構築2009

    • Author(s)
      藤岡健太・梁興国・浅沼浩之, 他
    • Organizer
      第24回生体機能関連化学シンポジウム・第12回バイオテクノロジー部会シンポジウム
    • Place of Presentation
      福岡 九州大学
    • Related Report
      2009 Annual Research Report
  • [Presentation] DNA塩基対とアゾベンゼンを交互に配置した新規光応答性二重らせんの構築2009

    • Author(s)
      望月敏夫・梁興国・浅沼浩之
    • Organizer
      第24回生体機能関連化学シンポジウム
    • Place of Presentation
      福岡 九州大学
    • Related Report
      2009 Annual Research Report
  • [Presentation] 制限酵素を活用した常温下でのDNA増幅法の開発2009

    • Author(s)
      鈴木晶友・加藤智博・梁興国浅沼浩之
    • Organizer
      第24回生体機能関連化学シンポジウム
    • Place of Presentation
      福岡 九州大学
    • Related Report
      2009 Annual Research Report
  • [Presentation] 蛍光色素のDNAを足場とした会合制御による多色“DNAドット"の創製2009

    • Author(s)
      関口康司・高津智彦・樫田啓・浅沼浩之
    • Organizer
      第24回生体機能関連化学シンポジウム・第12回バイオテクノロジー部会シンポジウム
    • Place of Presentation
      福岡 九州大学
    • Related Report
      2009 Annual Research Report
  • [Presentation] カチオン性擬似塩基対形成によるDNA二重鎖の安定化2009

    • Author(s)
      林威光・藤井大雅・樫田啓・浅沼浩之
    • Organizer
      第24回生体機能関連シンポジウム
    • Place of Presentation
      福岡 九州大学
    • Related Report
      2009 Annual Research Report
  • [Presentation] プロトン化に伴う蛍光変化を利用したDNA二重鎖形成の検出2009

    • Author(s)
      山口恭平・原雄一・樫田啓・浅沼浩之
    • Organizer
      第24回生体関連化学シンポジウム
    • Place of Presentation
      福岡 九州大学
    • Related Report
      2009 Annual Research Report
  • [Presentation] 光駆動型DNAナノデバイスの構築とその応用2009

    • Author(s)
      梁興国・浅沼浩之, 他
    • Organizer
      第58回高分子討論会
    • Place of Presentation
      熊本大学、熊本
    • Related Report
      2009 Annual Research Report
  • [Presentation] ステム内部での色素会合を利用した高感度モレキュラービーコンの開発2009

    • Author(s)
      樫田啓・梁興国・浅沼浩之, 他
    • Organizer
      第58回高分子討論会
    • Place of Presentation
      熊本大学
    • Related Report
      2009 Annual Research Report
  • [Presentation] 複数のメチル化アゾベンゼンを導入したDNAによるハイブリダイゼーションの高効率光制御2009

    • Author(s)
      西岡英則・梁興国・浅沼浩之
    • Organizer
      第58回高分子討論会
    • Place of Presentation
      熊本大学
    • Related Report
      2009 Annual Research Report
  • [Presentation] カチオン性色素-リン酸の静電相互作用を利用したDNA二重鎖の安定化2009

    • Author(s)
      林威光・藤井大雅・樫田啓・浅沼浩之
    • Organizer
      第58回高分子討論会
    • Place of Presentation
      熊本大学
    • Related Report
      2009 Annual Research Report
  • [Presentation] DNAへの蛍光色素の多数導入による“DNAドット"の創製2009

    • Author(s)
      関口康司・高津智彦・樫田啓・浅沼浩之
    • Organizer
      第58回高分子討論会
    • Place of Presentation
      熊本大学
    • Related Report
      2009 Annual Research Report
  • [Presentation] アゾベンゼンの光異性化を利用した光応答性DNAzyme 10-23 の開発2009

    • Author(s)
      周孟光・望月敏夫・梁興国・浅沼浩之
    • Organizer
      中部化学関係学協会支部連合協議会
    • Place of Presentation
      岐阜大学
    • Related Report
      2009 Annual Research Report
  • [Presentation] DNAを足場とした励起子相互作用を伴う異種色素のクラスター化2009

    • Author(s)
      藤井大雅・樫田啓・浅沼浩之
    • Organizer
      第3回物質科学フロンティアセミナー -ものづくりを基盤とする最先端科学 : 分子の設計、創造、そして解明-
    • Place of Presentation
      名古屋大学
    • Related Report
      2009 Annual Research Report
  • [Presentation] ヒト細胞におけるアゾベンゼン修飾RNAのRNA干渉への応用2009

    • Author(s)
      伊藤浩・西岡英則・梁興国・浅沼浩之
    • Organizer
      第3回物質科学フロンティアセミナー
    • Place of Presentation
      名古屋大学
    • Related Report
      2009 Annual Research Report
  • [Book] 最先端メディカルエンジニアリング2013

    • Author(s)
      浅沼浩之、樫田啓
    • Total Pages
      6
    • Publisher
      一粒書房
    • Related Report
      2012 Annual Research Report
  • [Book] Oligonucleotide Conjugates for Detection of Specific Nucleic Acid Sequences2012

    • Author(s)
      Kashida, H.; Asanuma, H, "DNA Conjugates and Sensors" Eds. by K. R. Fox, T. Brown
    • Publisher
      RSC Publishing
    • Related Report
      2012 Final Research Report
  • [Book] DNA Conjugates and Sensors2012

    • Author(s)
      Kashida, H.; Asanuma, H.
    • Total Pages
      15
    • Publisher
      RSC Publishing
    • Related Report
      2012 Annual Research Report
  • [Book] 梁興国, "核酸化学のニュートレンド"、カートリッジ型人工ヌクレオチドによる光応答性DNAの設計2011

    • Author(s)
      浅沼浩之、日本化学会編
    • Publisher
      化学同人
    • Related Report
      2012 Final Research Report
  • [Book] カートリッジ型人工ヌクレオチドによる光応答性DNAの設計2011

    • Author(s)
      浅沼浩之・梁興国
    • Publisher
      化学同人
    • Related Report
      2011 Annual Research Report
  • [Book] バイオチップ実用化ハンドブック(人工核酸を利用したプローブDNAの調製と遺伝子多型検出)2010

    • Author(s)
      樫田啓、浅沼浩之
    • Total Pages
      8
    • Publisher
      エヌ・ティー・エス
    • Related Report
      2010 Annual Research Report
  • [Remarks]

    • URL

      http://www.nubio.nagoya-u.ac.jp/seigyo1/index.html

    • Related Report
      2012 Final Research Report
  • [Remarks]

    • URL

      http://www.nubio.nagoya-u.ac.jp/seigyol/member01_2.html

    • Related Report
      2010 Annual Research Report
  • [Patent(Industrial Property Rights)] 蛍光標識オリゴヌクレオチド誘導体及びその利用2011

    • Inventor(s)
      浅沼浩之、樫田啓、近藤展代、大澤卓矢、赤羽真理子
    • Industrial Property Rights Holder
      国立大学法人名古屋大学
    • Industrial Property Number
      2011-221332
    • Filing Date
      2011-10-05
    • Related Report
      2011 Annual Research Report
  • [Patent(Industrial Property Rights)] オリゴヌクレオチド及びその利用2011

    • Inventor(s)
      丸山厚、浅沼浩之, 他
    • Industrial Property Rights Holder
      日本碍子株式会社
    • Industrial Property Number
      2011-033986
    • Filing Date
      2011-02-18
    • Related Report
      2010 Annual Research Report
  • [Patent(Industrial Property Rights)] オリゴヌクレオチドおよびその利用2010

    • Inventor(s)
      浅沼浩之、梁興国、他 4 名
    • Industrial Property Rights Holder
      法人名古屋大学
    • Industrial Property Number
      2010-194942
    • Filing Date
      2010-08-31
    • Related Report
      2012 Final Research Report
  • [Patent(Industrial Property Rights)] オリゴヌクレオチド及びその利用2010

    • Inventor(s)
      浅沼浩之、梁興国, 他
    • Industrial Property Rights Holder
      名古屋大学
    • Industrial Property Number
      2010-194942
    • Filing Date
      2010-08-31
    • Related Report
      2010 Annual Research Report
  • [Patent(Industrial Property Rights)] オリゴヌクレオチド及びその利用2010

    • Inventor(s)
      浅沼浩之、樫田啓, 他
    • Industrial Property Rights Holder
      名古屋大学
    • Industrial Property Number
      2010-206043
    • Filing Date
      2010-09-14
    • Related Report
      2010 Annual Research Report

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Published: 2009-04-01   Modified: 2019-07-29  

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