Regulatory Roles and Networks of the Whole Set of Transcription Factors in Escherichia coli

• Project/Area Number: 21241047
• Research Category: Grant-in-Aid for Scientific Research (A)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: 基礎ゲノム科学
• Research Institution: Hosei University
• Principal Investigator: ISHIHAMA Akira 法政大学, 企画戦略本部, 特任教授 (80019869)
• Project Period (FY): 2009 – 2011
• Project Status: Completed (Fiscal Year 2011)
• Budget Amount: ¥44,980,000 (Direct Cost: ¥34,600,000、Indirect Cost: ¥10,380,000); Fiscal Year 2011: ¥15,080,000 (Direct Cost: ¥11,600,000、Indirect Cost: ¥3,480,000); Fiscal Year 2010: ¥16,380,000 (Direct Cost: ¥12,600,000、Indirect Cost: ¥3,780,000); Fiscal Year 2009: ¥13,520,000 (Direct Cost: ¥10,400,000、Indirect Cost: ¥3,120,000)
• Keywords: ゲノム制御 / 転写制御 / 転写因子 / 大腸菌 / ストレス応答 / RNAポリメラーゼ / プロモーター / 制御ネットワーク / Genomic SELEX / 転写調節 / 環境応答 / 転写制御ネットワーク / RNAボリメラーゼ / Phenotype microarray / 原核生物

Research Abstract

The genome expression is determined by controlling the distribution of a limited number of RNA polymerase within the genome through interaction with transcription factors. The aim of this research was to identify the regulatory role of all 300 transcription factors in the model prokaryote, Escherichia coli.
1) We developed the in vitro Genomic SELEX screening system and determined the regulation target genes for all 300 transcription factors.
2) We also developed the in vivo NIP-chip system and determined the intracellular distribution of transcription factors within the E. coli genome.
3) The regulation targets thus predicted were examined by measuring their expression in the presence and absence of transcription factors.
4) We determined the intracellular levels of all 300 transcription factors by using quantitative immune-blot analysis.
5) Taking all the results together, I have proposed :(1) the list of regulation targets for all 300 transcription factors ; and(2) the interaction network of 300 transcription factors, altogether forming complex hierarchic regulation networks.

Research Products

• [Journal Article] Prokaryotic genome regulation : Multi-factor promoters and multi-target regulators (2012)
  • Author(s): Ishihama, A.
  • Journal Title: Proc. Jpn. Acad Volume: (in press)
  • Peer Reviewed
• [Journal Article] Regulation targets of metal-response BasS-BasR two-component system in Escherichia coli : Modification of cell membrane (2012)
  • Author(s): Ogasawara, H., Shinohara, S. and Ishihama, A.
  • Journal Title: Microbiology Volume: 158 Pages: 1482-1492
  • Peer Reviewed
• [Journal Article] Induction of YdeO, a regulator for acid resistance gene, by ultraviolet irradiation in Escherichia coli (2012)
  • Author(s): Yamanaka, Y., Ishihama, A. and Yamamoto, K.
  • Journal Title: Biosci. Biotechnol. Biochem Volume: 76
  • NAID: 10030818581
  • Peer Reviewed
• [Journal Article] Increase in cell viability by polyamines through stimulation of the synthesis of ppGpp regulatory protein and protein in Escherichia coli. (2012)
  • Author(s): Terui, Y., Akiyama, M., Sakamoto, A., Tomitori, H., Yamamoto, K., Ishihama, A., Igarashi, K. and Kashiwagi, K.
  • Journal Title: J. Biochem. Cell Biol Volume: 44 Pages: 412-422
  • Peer Reviewed
• [Journal Article] Transcription factors and transcriptional apparatus in bacteria (2012)
  • Author(s): Ishihama, A.
  • Journal Title: Encyclopedia of Systems Biology Volume: (In press)
  • Peer Reviewed
• [Journal Article] Detection of bacterial bahits : Single planktonic cells and assembled biofilm (2012)
  • Author(s): Ishihama, A.
  • Journal Title: Nanomedicine in Diagnostics Volume: (In press)
  • Peer Reviewed
• [Journal Article] Regulation targets of metal-response BasS-BasR two-component system in Escherichia coli : Modification of cell membrane (2012)
  • Author(s): Ogasawara, H., Shinohara, S., Ishihama, A.
  • Journal Title: Microbiology Volume: 158(In press) Issue: 6 Pages: 1482-1492
  • DOI: 10.1099/mic.0.057745-0
  • Peer Reviewed
• [Journal Article] Induction of YdeO, a regulator for acid resistance genes, by ultraviolet irradiation in Escherichia coli (2012)
  • Author(s): Yamanaka, Y., Ishihama, A., Yamamoto, K.
  • Journal Title: Biosci.Biotechnol.Biochem. Volume: (In press)
  • NAID: 10030818581
  • Peer Reviewed
• [Journal Article] 5'-UTR of mor1, an unexpected transcript repressed by ModE, affects cell growth in Escherichia coli (2012)
  • Author(s): Hiramatsu, M., Ogasawara, Ishihama, A., Yamamoto, K.
  • Journal Title: Biosci.Biotechnol.Biochem. Volume: (In press)
  • Peer Reviewed
• [Journal Article] Single molecule analysis of transcription factor-DNA complexes using atomic force microscopy (2012)
  • Author(s): Nakano, M., Teramoto, J., Shimada, T., Yamamoto, K., Ishihama, A.
  • Journal Title: Micro-Nano Mechatronics Human Sci. Volume: (In press)
  • Peer Reviewed
• [Journal Article] Increase in cell viability by polyamines through stimulation of the synthesis of ppGpp regulatory protein and w protein in Escherichia coli (2012)
  • Author(s): Terui, Y., Akiyama, M., Tomitori, H., Yamamoto, K., Ishihama, A., Igarashi, K., Kashiwagi, K
  • Journal Title: Internatl.J.Biochem.Cell Biol. Volume: 44 Issue: 37 Pages: 412-422
  • DOI: 10.1074/jbc.m110.111195
  • Peer Reviewed
• [Journal Article] RodZ(YfgA), a bacterial cytoskeletal protein, regulates expression of type III secretion system in Shigella sonnei through post-transcriptional processing (2011)
  • Author(s): Mitobe, J., Yanagihara, I., Ohnishi, K., Ishihama, A. and Watanabe, H.
  • Journal Title: EMBO Reports Volume: 12 Pages: 911-916
  • Peer Reviewed
• [Journal Article] Cross-regulation between biofilm formation and flagella synthesis : Role of biofilm master regulator CsgD (2011)
  • Author(s): Ogasaawara, H., Yamamoto, K. and Ishihama, A.
  • Journal Title: J. Bacteriol Volume: 193(10) Pages: 2587-2597
  • Peer Reviewed
• [Journal Article] Novel roles of LeuO in transcription regulation in E. coli : Antagonistic interplay with the universal silencer H-NS (2011)
  • Author(s): Shimada, T., Bridier, A., Briandet, R. and Ishihama, A.
  • Journal Title: Mol. Microbiol Volume: 81
  • Peer Reviewed
• [Journal Article] Novel roles of cAMP receptor protein(CRP) in regulation of transport and metabolism of carbon sources (2011)
  • Author(s): Shimada, T., Fujita, N., Yamamoto, K. and Ishihama, A.
  • Journal Title: PLoS ONE Volume: 6(6)
  • Peer Reviewed
• [Journal Article] Novel members of the Cra regulon involved in carbon metabolism in Escherichia coli (2011)
  • Author(s): Shimada, T., Yamamoto, K. and Ishihama, A.
  • Journal Title: J. Bacteriol Volume: 193(3) Pages: 649-659
  • Peer Reviewed
• [Journal Article] The Escherichia coli K-12 MntR mini-regulon includes dps that encodes the major stationary phase DNA-binding protein (2011)
  • Author(s): Yamamoto, K., Ishihama, A., Busby, S. J. W. and Brainger, D. C.
  • Journal Title: J. Bacteriol Volume: 193(6) Pages: 1477-1480
  • Peer Reviewed
• [Journal Article] RodZ (YfgA), a bacterial cytoskeletal protein, regulates expression of type III secretion system in Shigella sonnei through post-transcriptional processing (2011)
  • Author(s): Mitobe, J., Yanagihara, I., Ohnishi, K., Ishihama, A., Watanabe, H.
  • Journal Title: EMBO Reports Volume: 12 Pages: 911-916
  • Peer Reviewed
• [Journal Article] Cros-regulation between biofilm formationand flagella synthesis : Role of biofilm master regulator CsgD (2011)
  • Author(s): Ogasaawara, H., Yamamoto, K., Ishihama, A.
  • Journal Title: J.Bacteriol. Volume: 193 Issue: 10 Pages: 2587-2597
  • DOI: 10.1128/jb.01468-10
  • Peer Reviewed
• [Journal Article] Novel roles of LeuO in transcription regulation in E.coli : Antagonistic interplay with the universal silencer H-NS (2011)
  • Author(s): Shimada, T., Bridier, A., Briandet, R., Ishihama, A.
  • Journal Title: Mol.Microbiol. Volume: 82 Issue: 2 Pages: 376-397
  • DOI: 10.1111/j.1365-2958.2011.07818.x
  • Peer Reviewed
• [Journal Article] Novel roles of CAMP receptor protein (CRP) in regulation of transport and metabolism of carbon sources (2011)
  • Author(s): Shimada, T., Fujita, N., Yamamoto, K., Ishihama, A.
  • Journal Title: PLoS One Volume: 193 Issue: 6 Pages: 649-659
  • DOI: 10.1371/journal.pone.0020081
  • Peer Reviewed
• [Journal Article] Novel roles of cAMP receptor protein (CRP) in regulation of transport and metabolism of carbon sources (2011)
  • Author(s): Shimada, T., Fujita, N., Yamamoto, K., Ishihama, A.
  • Journal Title: PLoS One Volume: 193 Issue: 3 Pages: 649-659
  • DOI: 10.1128/jb.01214-10
  • Peer Reviewed
• [Journal Article] Ribosome modulation fector, an important protein for cell viability encoded by the polyamine modulon (2011)
  • Author(s): Terui, Y., Tabei, Y., Ishihama, A., Igarashi, K., Kashiwagi, K.
  • Journal Title: J.Biol.Chem. Volume: 285 Pages: 28698-28707
  • Peer Reviewed
• [Journal Article] The Escherichia coli K-12 MntR mini-regulon includes dps that encodes the major stationary phase DNA-binding protein (2011)
  • Author(s): Yamamoto, K., Ishihama, A., Busby, S.J.W., Brainger, D.C.
  • Journal Title: J.Bacteriol. Volume: 139 Issue: 6 Pages: 1477-1480
  • DOI: 10.1128/jb.01230-10
  • Peer Reviewed
• [Journal Article] Induction of the Escherichia coli cysK gene by genetic and environmental factors (2011)
  • Author(s): Yamamoto, K., Oshima, T., Nonaka, G., Ito, H., Ishihama, A
  • Journal Title: FEMS Microb.Lett. Volume: 323 Issue: 1 Pages: 88-95
  • DOI: 10.1111/j.1574-6968.2011.02364.x
  • Peer Reviewed
• [Journal Article] Novel members of the Cra regulon involved in carbon metabolism in Escherichia coli. (2011)
  • Author(s): Shimada, T.
  • Journal Title: J.Bacteriol. Volume: 193(3) Pages: 649-659
  • Peer Reviewed
• [Journal Article] The Escherichia coli K-12 MntR mini-regulon includes dps that encodes the major stationary phase DNA-binding protein. (2011)
  • Author(s): Yamamoto, K.
  • Journal Title: J.Bacteriol. Volume: 193(6) Pages: 1477-1480
  • Peer Reviewed
• [Journal Article] Cross-regulation between biofilm formationand flagella synthesis : Role of biofilm master regulator CsgD. (2011)
  • Author(s): Ogasaawara, H.
  • Journal Title: J.Bacteriol. Volume: 193(10)(in press)
  • Peer Reviewed
• [Journal Article] Novel roles of cAMP receptor protein (CAP) in regulation of transport and metabolism of carbon sources. (2011)
  • Author(s): Shimada, T.
  • Journal Title: PLoS ONE Volume: 6(in press)
  • Peer Reviewed
• [Journal Article] Prokaryotic genome regulation : Multi-factor promoters, multi-target regulators and hierarchic networks (2010)
  • Author(s): Ishihama, A.
  • Journal Title: FEMS Microbial Reviews Volume: 34 Pages: 628-645
  • Peer Reviewed
• [Journal Article] The E. coli csgD promoter : Interplay between eight transcription factors (2010)
  • Author(s): Ogasawara, H., Yamada, K., Kori, A., Yamamoto, K. and Ishihama, A.
  • Journal Title: Microbiology Volume: 156(8) Pages: 2470-2483
  • Peer Reviewed
• [Journal Article] Regulatory role of MlrA in transcription activation of csgD, the master regulator of biofilm formation in Escherichia coli (2010)
  • Author(s): Ogasawara, H., Yamamoto, K. and Ishihama, A.
  • Journal Title: FEMS Microbiol. Lett Volume: 312 Pages: 160-168
  • Peer Reviewed
• [Journal Article] Single live-bacterial cell assay of promoter activity and regulat (2010)
  • Author(s): Teramoto, J., Yamanishi, Y., Magdy, E-S. H., Hasegawa, A., Kori, A., Nakajima, M., Arai, F., Fukuda, T. and Ishihama, A.
  • Journal Title: Genes Cells Volume: 15 Pages: 1111-1112
  • Peer Reviewed
• [Journal Article] A novel nucleoid protein of Escherichia coli induced under anaerobic growth conditions (2010)
  • Author(s): Teramoto, J., Yoshimura, S. H., Takeyasu, K. and Ishihama, A.
  • Journal Title: Nucleic Acids Res Volume: 38(11) Pages: 3605-3618
  • Peer Reviewed
• [Journal Article] Ribosome modulation factor, an important protein for cell viability encoded by the polymodulon modulon (2010)
  • Author(s): Terui, Y., Tabei, Y., Akiyama, M., Tomitori, H., Yamamoto, K., Ishihama, A., Igarashi, K. and Kashiwagi, K.
  • Journal Title: J. Biol. Chem Volume: 285 Pages: 28698-28707
  • Peer Reviewed
• [Journal Article] Prokaryotic genome regulation : Multi-factor promoters, multi-target regulators and hierarchic networks. (2010)
  • Author(s): Ishihama, A.
  • Journal Title: FEMS Microbial Reviews Volume: 34 Pages: 625-645
  • Peer Reviewed
• [Journal Article] The E.coll csgD promoter : Interplay between eight transcription factors. (2010)
  • Author(s): Ogasawara, H.
  • Journal Title: Microbiology Volume: 158(8) Pages: 2470-2783
  • Peer Reviewed
• [Journal Article] Regulatory role of MlrA in transcription activation of csgD, the master regulator of biofilm formation in Escherichia coli. (2010)
  • Author(s): Ogasawara, H.
  • Journal Title: FEMS Microbiol.Lett. Volume: 312(2) Pages: 160-168
  • Peer Reviewed
• [Journal Article] Single live-bacterial cell assay of promoter activity and regulation. (2010)
  • Author(s): Teramoto, J.
  • Journal Title: Genes Cells Volume: 15 Pages: 1111-1122
  • Peer Reviewed
• [Journal Article] A novel nucleoid protein of Escherichia coli induced under anaerobic growth conditions. (2010)
  • Author(s): Teramoto, J.
  • Journal Title: Nucleic Acids Res. Volume: 38(11) Pages: 3605-3618
  • Peer Reviewed
• [Journal Article] Ribosome modulation factor, an important protein for cell viability encoded by the polymodulon modulon. (2010)
  • Author(s): Terui, Y.
  • Journal Title: J.Biol.Chem. Volume: 285(37) Pages: 28698-28707
  • Peer Reviewed
• [Journal Article] Genomic SELEX for the genome-wide search of regulation targets by transcription factors ; SELEX-clos and SELEX-chip procedures. (2010)
  • Author(s): Shimada, T.
  • Journal Title: Proc.Internatl. Symp.Micro-Nano Mechatronics Human Sci. Volume: 2010 Pages: 100-103
  • Peer Reviewed
• [Journal Article] Prokaryotic genome regulation : Multi-factor promoters, multi-target regulators and hierarchic networks. (2010)
  • Author(s): Ishihama, A.
  • Journal Title: FEMS Microb.Rev. 34(In press)
  • Peer Reviewed
• [Journal Article] Promoter regulation of the E.coli csgD gene : Interplay between eight transcription factors in promoter binding. (2010)
  • Author(s): Ogasawara, H., Yamada, K., Kori, A., Yamamoto, K., Ishihama, A.
  • Journal Title: Microbiology 156(In press)
  • Peer Reviewed
• [Journal Article] Nucleic Acids Res. (2010)
  • Author(s): Teramoto, J., Yoshimura, S.H., Takeyasu, K., Ishihama, A.
  • Journal Title: A novel nucleoid protein of Escherichia coli induced under anaerobic growth conditions. 38(In press)
  • Peer Reviewed
• [Journal Article] Participation of regulator AscG of the b. glucoside utilization operon in regulation of the propionate catabolism operon (2009)
  • Author(s): Ishida, Y., Kori, A. and Ishihama, A.
  • Journal Title: J. Bacteriol Volume: 191 Pages: 6136-6144
  • Peer Reviewed
• [Journal Article] Two modes of autoregulation of the murR repressor in Escherichia coli (2009)
  • Author(s): Ishii, D., Ishihama, A. and Yamamoto, K.
  • Journal Title: Biosci. Biotechnol. Biochem Volume: 73
  • NAID: 10027548218
• [Journal Article] Involvement of RNA-binding protein Hfq in the osmotic-response regulation of invE gene expression in Shigella sonnei (2009)
  • Author(s): Mitobe, J., Morita-Ishihara, T., Ishihama, A. and Watanabe, H.
  • Journal Title: BMC Microbiol Volume: 9 Pages: 110-110
  • Peer Reviewed
• [Journal Article] Involvement of leucine-reponse transcription factor LeuO in regulation of the genes for sulfa-drug efflux (2009)
  • Author(s): Shimada, T., Yamamoto, K. and Ishihama, A.
  • Journal Title: J. Bacteriol Volume: 191 Pages: 4562-4571
  • Peer Reviewed
• [Journal Article] Enhancement of the synthesis of RpoE and StpA by polyamines at the level of translation in Escherichia coli under heat shock conditions (2009)
  • Author(s): Terui, Y., Higashi, K., Tabei, Y., Tomitori, H., Yamamoto, K., Ishihama, A., Igarashi, K. and Kashiwagi, K.
  • Journal Title: J. Baceriol Volume: 191 Pages: 5348-5357
  • Peer Reviewed
• [Journal Article] Characterization of CitA-CitB signal transduction activating genes involved in anaerobiccitrate catabolism in Escherichia coli (2009)
  • Author(s): Yamamoto, K., Matsumoto, F., Minagawa, S., Oshima, T., Fujita, N., Ogasawara, N. and Ishihama, A.
  • Journal Title: Biosci. Biotechnonl. Biochem Volume: 73 Pages: 346-350
  • Peer Reviewed
• [Journal Article] Participation of regulator AscG of the β-glucoside utilization operon in regulation of the propionate catabolism operon. (2009)
  • Author(s): Ishida, Y., Kori, A., Ishihama, A.
  • Journal Title: J.Bacteriol. 191 Pages: 6136-6144
  • Peer Reviewed
• [Journal Article] Two modes of autoregulation of the murR repressor in Escherichia coll. (2009)
  • Author(s): Ishii, D., Ishihama, A., Yamamoto, K.
  • Journal Title: Biosci. Biotechnonl. Biochem. 73
  • Peer Reviewed
• [Journal Article] Involvement of RNA-binding protein Hfq in the osmotic-response regulation of invE gene expression in Shigella sonnei. (2009)
  • Author(s): Mitobe, J., Morita-Ishihara, T., Ishihama, A., Watanabe, H.:
  • Journal Title: BMC Microbiol. 9 Pages: 110-110
  • Peer Reviewed
• [Journal Article] Regulation of the E.coli csgD gene encoding the master regulator of biofilm formation : Interplay between multiple transcription factors 0925023GC004 Micro-Nano Mechatronics Human Sci. (2009)
  • Author(s): Ogasawara, H., Kori, A., Yamada, K., Yamamoto, K., Ishihama, A.
  • Journal Title: 2009 Pages: 186-190
  • Peer Reviewed
• [Journal Article] Genomic SELEX for the genome-wide search of regulation targets by transcription factors : SELEX-clos and SELEX-chip procedures. (2009)
  • Author(s): Shimada, T., Fujita, N., Yamamoto, Y., Ishihama, A.
  • Journal Title: Micro-Nano Mechatronics Human Sci. 2009 Pages: 175-178
  • Peer Reviewed
• [Journal Article] Involvement of leucine-reponse transcription factor LeuO in regulation of the genes for sulfa-drug efflux. (2009)
  • Author(s): Shimada, T., Yamamoto, K., Ishihama, A.
  • Journal Title: J.Bacteriol. 191 Pages: 4552-4571
  • Peer Reviewed
• [Journal Article] Anaerobiosis-Induced novel nucleoid protein of Escherichia coli. Architectural role in genome DNA compaction. (2009)
  • Author(s): Teramoto, J., Yamada, K., Kobayashi, N., Kori, A., Yoshimura, S.H., Takeyasu, K., Ishihama, A.
  • Journal Title: Micro-Nano Mechatronics Human Sci. 2009 Pages: 179-182
  • Peer Reviewed
• [Journal Article] Single live-bacterial cell assay of promoter activity and regulation : Escherichia coli gcl promoter. (2009)
  • Author(s): Teramoto, J., Yamanishi, Y., Magdy, E-S.H., Hasegawa, A., Nakajima, M., Shimada, T., Arai, F., Fukuda, T., Ishihama, A.
  • Journal Title: Micro-Nano Mechatronics Human Sci. 2009 Pages: 175-178
  • Peer Reviewed
• [Journal Article] Enhancement of the synthesis of RpoE and StpA by polyamines at the level of translation in Escherlchia coli under heat shock conditions. (2009)
  • Author(s): Terui, Y., Higashi, K., Tabei, Y., Tomitori, H., Yamamoto, K., Ishihama, A., Igarashi, K., Kashiwaqi, K.
  • Journal Title: J.Bacteriol. 191 Pages: 5348-5357
  • Peer Reviewed
• [Journal Article] Characterization of CitA-CitB signal transduction activating genes involved in anaerobiccitrate catabolism in Escherichia coli. (2009)
  • Author(s): Yamamoto, K., Matsumoto, F., Minagawa, S., Oshima, T., Fujita, N., Ogasawara, N., Ishihama, A.
  • Journal Title: Biosci. Biotechnonl. Biochem. 73 Pages: 346-350
  • Peer Reviewed
• [Journal Article] On-chip cell immobilization and monitoring system using thermosensitive gel controlled by suspended polymeric microbridge. (2009)
  • Author(s): Yamanishi, Y., Teramoto, J., Magariyama, Y., Ishihama, A., Fukuda, T., Arai, F.
  • Journal Title: IEEE Transaction NanoBioscience 8 Pages: 312-317
  • Peer Reviewed
• [Journal Article] On-chip temperature control under suspended microbridge for cell immobilization and culture system. (2009)
  • Author(s): Yamanishi, Y., Teramoto, J., Magariyama, Y., Ishihama, A., Fukuda, T., Arai, F.
  • Journal Title: Proc. 13^<th> Internati.Conf. Miniaturized Systems for Chemist.Life Sci 2009
• [Presentation] Global Regulation of Prokaryotic Genome Transcription (2012)
  • Author(s): Ishihama, A.
  • Organizer: JN Centre for Advanced Scientific Research(JNCASR) Seminar
  • Place of Presentation: Bangalore
  • Year and Date: 2012-03-19
• [Presentation] Global Regulation of Prokaryotic Genome Transcription. Attempts toward Understanding the Regulatory Roles for All 300 Transcription Factors in Escherichia coli (2012)
  • Author(s): Ishihama, A.
  • Organizer: JN Contre for Advanced Scientific Research (JNCASR) Seminar
  • Place of Presentation: JNCASR, Bangalore, India(招待講演)
  • Year and Date: 2012-03-19
• [Presentation] 「細菌ゲノム転写の包括制御機構」-ひとつの生物のすべての転写因子の制御機能の理解を目指して- (2012)
  • Author(s): 石浜明
  • Organizer: 東北大学グローバルCOE, Network Medicine創生拠点、NM高等教育セミナー
  • Place of Presentation: 東北大学,仙台(招待講演)
  • Year and Date: 2012-03-18
• [Presentation] 大腸菌転写因子LeuOのゲノム転写制御における新規役割:Universal Silencer H-NSに対する拮抗作用 (2012)
  • Author(s): 島田友裕、Arnaud Brider、Romain Briandet、石浜明
  • Organizer: 第6回日本ゲノム微生物学会年会
  • Place of Presentation: 立教大学,東京
  • Year and Date: 2012-03-10
• [Presentation] 大腸菌機能未知転写因子YiaUの制御標的遺伝子群の同定と機能解析 (2012)
  • Author(s): 村山里枝、島田友裕、小笠原寛、片山泰徳、郡彩子、石浜明
  • Organizer: 第6回日本ゲノム微生物学会年会
  • Place of Presentation: 立教大学,東京
  • Year and Date: 2012-03-10
• [Presentation] 大腸菌機能未知転写因子YegWの転写発現制御機能の解析 (2012)
  • Author(s): 保科元気、島田友裕、佐藤史佳、山田佳代子、郡彩子、石浜明
  • Organizer: 第6回日本ゲノム微生物学会年会
  • Place of Presentation: 立教大学,東京
  • Year and Date: 2012-03-10
• [Presentation] 「細菌ゲノム転写の包括制御機構」ひとつの生物のすべての転写因子の制御機能の理解を目指して- (2012)
  • Author(s): 石浜明
  • Organizer: 東北大学グローバルCOE, Network Medicine創生拠点、NM高等教育セミナー
  • Place of Presentation: 東北大学医学部
  • Year and Date: 2012-03-08
• [Presentation] 大腸菌転写因子LeuOのゲノム転写制御における新規役割:Universal Silencer H-NSに対する拮抗作用 (2011)
  • Author(s): 島田友裕、Arnaud Brider、Romain Briandet、石浜明
  • Organizer: 第34回日本分子生物学会年会
  • Place of Presentation: パシフィコ横浜、横浜
  • Year and Date: 2011-12-13
• [Presentation] 大腸菌機能未知転写因子YbjKの制御標的遺伝子群の同定と制御機能解析 (2011)
  • Author(s): 片山泰徳、河北寿一、島田友裕、郡彩子、山田佳代子、山本兼由、石浜明
  • Organizer: 第34回日本分子生物学会年会
  • Place of Presentation: パシフィコ横浜、横浜
  • Year and Date: 2011-12-13
• [Presentation] 大腸菌転写因子SdiAの新規標的遺伝子群の探索とQSシグナル感知機能の解析 (2011)
  • Author(s): 島田佳織、鍛代悠一、松井誠、島田友裕、五十嵐潤、菅裕明、山本兼由、石浜明
  • Organizer: 第34回日本分子生物学会年会
  • Place of Presentation: パシフィコ横浜、横浜
  • Year and Date: 2011-12-13
• [Presentation] 大腸菌機能未知転写因子YegWの遺伝子発現制御機構の解析 (2011)
  • Author(s): 保科元気、島田友裕、佐藤史佳、荒井明菜、山田佳代子、郡彩子、石浜明
  • Organizer: 第34回日本分子生物学会年会
  • Place of Presentation: パシフィコ横浜、横浜
  • Year and Date: 2011-12-13
• [Presentation] 大腸菌機能未知転写因子YiaUの制御標的遺伝子群の同定と機能解明 (2011)
  • Author(s): 村山里枝, 島田友裕, 小笠原寛, 片山泰徳, 郡彩子, 山田佳代子, 石浜明
  • Organizer: 第34回日本分子生物学会年会
  • Place of Presentation: パシフィコ横浜、横浜
  • Year and Date: 2011-12-13
• [Presentation] 亜鉛による大腸菌csgDプロモーターの発現抑制機構 (2011)
  • Author(s): 小笠原寛、山本兼由、石浜明
  • Organizer: 第34回日本分子生物学会年会
  • Place of Presentation: パシフィコ横浜、横浜
  • Year and Date: 2011-12-13
• [Presentation] Novel role of YdeO-regulon for acid resistance in Escherichia coli. Novel role of YdeO-regulon for acid resistance in Escherichia coli (2011)
  • Author(s): Yamanaka, Y., Oshima, T., Ishihama, A., Yamamoto, K.
  • Organizer: 第34回日本分子生物学会年会
  • Place of Presentation: パシフィコ横浜、横浜
  • Year and Date: 2011-12-13
• [Presentation] カイコ体内で発現する大腸菌プロモーターの探索 (2011)
  • Author(s): 飯島拓郎、皆川周、後藤直正、石浜明、山本兼由
  • Organizer: 第34回日本分子生物学会年会
  • Place of Presentation: パシフィコ横浜、横浜
  • Year and Date: 2011-12-13
• [Presentation] 大腸菌K-12ゲノムの新規同定ModE支配下遺伝子mor1の5'UTRによる生育抑制 (2011)
  • Author(s): 倉田竜明、木口悠也、小笠原寛、石浜明、山本兼由
  • Organizer: 第34回日本分子生物学会年会
  • Place of Presentation: パシフィコ横浜、横浜
  • Year and Date: 2011-12-13
• [Presentation] 大腸菌プロモーターのin vitroにおける網羅的解析 (2011)
  • Author(s): 鈴木香織、山中幸、島田友裕、石浜明、山本兼由
  • Organizer: 第34回日本分子生物学会年会
  • Place of Presentation: パシフィコ横浜、横浜
  • Year and Date: 2011-12-13
• [Presentation] 大腸菌K-12株の全転写因子の発現解析 (2011)
  • Author(s): 渡邊宏樹、石浜明.山本兼由
  • Organizer: 第34回日本分子生物学会年会
  • Place of Presentation: パシフィコ横浜、横浜
  • Year and Date: 2011-12-13
• [Presentation] 大腸菌のモリブデン応答転写因子ModEレギュロンの解析 (2011)
  • Author(s): 木口悠也、倉田竜明、小笠原寛、石浜明、山本兼由
  • Organizer: 第34回日本分子生物学会年会
  • Place of Presentation: パシフィコ横浜、横浜
  • Year and Date: 2011-12-13
• [Presentation] 原子間力顕微鏡を用いた一分子解析による転写制御機構の解明 (2011)
  • Author(s): 中野雅博、島田友裕、寺本潤、山本兼由、石浜明
  • Organizer: 第34回日本分子生物学会年会
  • Place of Presentation: パシフィコ横浜、横浜
  • Year and Date: 2011-12-13
• [Presentation] Prokaryotic genome regulation : Multi-factor promoters, multi-target regulators and hierarchic networks (2011)
  • Author(s): Ishihama, A.
  • Organizer: 5^<th> IECA Conference 2011 on Gene Regulatory Networks in the Enterobacteiaceae
  • Place of Presentation: Xcaret, Mexico(招待講演)
  • Year and Date: 2011-12-07
• [Presentation] 大腸菌転写因子LeuOのゲノム転写制御における新規役割:Universal Silencer H-NSに対する拮抗作用 (2011)
  • Author(s): 島田友裕、Arnaud Brider, Romain Briander, 石浜明
  • Organizer: 第15回微生物研究会
  • Place of Presentation: 千葉大学農学部,松戸
  • Year and Date: 2011-11-12
• [Presentation] Single molecule analysis of transcription factor-DNA complexes using atomic force microscopy (2011)
  • Author(s): Nakano, M., Teramoto, J., Shimada, T., Ishihama, A.
  • Organizer: MHS2011&Micro-Nano Global COE
  • Place of Presentation: Nagoya Univ., Nagoya
  • Year and Date: 2011-11-08
• [Presentation] 大腸菌転写因子LeuOのゲノム転写制御における新規役割 (2011)
  • Author(s): 島田友裕、石浜明
  • Organizer: 日本ゲノム微生物学会若手の会
  • Place of Presentation: 労金研修所富士センター
  • Year and Date: 2011-09-29
• [Presentation] 大腸菌環境応答におけるゲノム転写の包括制御 (2011)
  • Author(s): 石浜明
  • Organizer: 第84回日本生化学会大会、シンポジウム
  • Place of Presentation: 京都国際会議場、京都(招待講演)
  • Year and Date: 2011-09-21
• [Presentation] 大腸菌の酸耐性能を制御するYdeOレギュロンの解析 (2011)
  • Author(s): 山中幸、大島拓、石浜明、山本兼由
  • Organizer: 第84回日本生化学会大会
  • Place of Presentation: 京都国際会議場、京都
  • Year and Date: 2011-09-21
• [Presentation] ポリアミンによるppGppの合成促進及びRpoZ-ppGpp複合体を介したRNA合成調節による大腸菌生の生存率上昇 (2011)
  • Author(s): 坂本明彦、照井祐介、秋山真律子、富取秀行、山本兼由、石浜明、五十嵐一衛、柏木敬子
  • Organizer: 第84回日本生化学会大会
  • Place of Presentation: 京都国際会議場、京都
  • Year and Date: 2011-09-21
• [Presentation] 大腸菌酸耐性システムにおけるYdeO機能の解析 (2011)
  • Author(s): 山中幸、大島拓、石浜明、山本兼由
  • Organizer: 日本ゲノム微生物学会ワークショップ
  • Place of Presentation: 東北大学、仙台
  • Year and Date: 2011-08-20
• [Presentation] 大腸菌酸耐性能を制御するYdeOレギュロンの解明 (2011)
  • Author(s): 山中幸、大島拓、石浜明、山本兼由
  • Organizer: 第5回日本細菌細菌学学会・若手コロッセウム
  • Place of Presentation: 高知大学、高知
  • Year and Date: 2011-08-08
• [Presentation] Anaerobiosis-induced nucleoid associated protein Dan polymerizes along ds DNA to form rigid helical-like co-filament that is able to concatemarize (2011)
  • Author(s): Lim, C.J., Lee, S.Y., Ishihama, A., Yan, J.
  • Organizer: Biophys.Soc.Meet."Dynamic DNA Packaging Across Kingdoms : Chromatin & Beyond"
  • Place of Presentation: Asilomar, Californica, USA
  • Year and Date: 2011-07-05
• [Presentation] Regulation of synthesis of Eschericia coli RNA polymerase sigma subunit in sepsis model infection in Drosophila (2011)
  • Author(s): Afwa Firdausi, Akiko Shiratsuchi, Ayako Kori, Akira Ishihama, Yoshinobu Nakanishi
  • Organizer: 日本分子生物学会第11回春季シンポジウム
  • Place of Presentation: 金沢県立音楽堂,金沢
  • Year and Date: 2011-05-25
• [Presentation] バイオフィルム統括転写調節因子CsgDの機能解明 (2011)
  • Author(s): 小笠原寛、山本兼由、石浜明
  • Organizer: 第8回大腸菌研究会
  • Place of Presentation: ホテル木曽路,南木曽、長野
  • Year and Date: 2011-05-18
• [Presentation] 細菌細胞の個性:細菌ゲノムの転写包括制御機構 (2011)
  • Author(s): 石浜明
  • Organizer: 信州大学ヒト環境科学研究支援センター
  • Place of Presentation: 信州大学,上田、長野(招待講演)
  • Year and Date: 2011-05-09
• [Presentation] 細菌細胞の個性:その分子基盤 (2011)
  • Author(s): 石浜明
  • Organizer: 九州大学G-COE「未来分子システム科学」公開セミナー
  • Place of Presentation: 九州大学先導物質化学研究所・福岡
  • Year and Date: 2011-02-09
• [Presentation] Anaerobiosis-induced nucleoid associated protein Dan polymerizes along dsDNA to form rigid helical-like co-filament that is able to concatemarize (2011)
  • Author(s): Lim, C. J., Lee, S. Y., Ishihama, A. and Yan, J.
  • Organizer: Biophys. Soc. Meet."Dynamic DNA Packaging Across Kingdoms"
  • Place of Presentation: Asilomar, Californica, USA
• [Presentation] 大腸菌環境応答におけるゲノム転写の包括制御 (2011)
  • Author(s): 石浜明
  • Organizer: 第84回日本生化学会大会
  • Place of Presentation: 京都・国際会議場
• [Presentation] ふたつの転写因子CRPとCraによる大腸菌炭素源代謝遺伝子群の転写制御の全体像 (2011)
  • Author(s): 島田友裕
  • Organizer: 日本農芸化学会2011年度大会
  • Place of Presentation: 京都女子大学
• [Presentation] バイオフィルム統括転写調節因子CsgDの機能解明 (2011)
  • Author(s): 小笠原寛
  • Organizer: 日本農芸化学会2011年度大会
  • Place of Presentation: 京都女子大学
• [Presentation] 細菌ゲノム制御全体像解明のための戦略戦術 (2010)
  • Author(s): 石浜明
  • Organizer: 日本大学学術研究高度化推進公開シンポジウム
  • Place of Presentation: 日大オープンリサーチセンター
  • Year and Date: 2010-06-30
• [Presentation] 大腸菌ゲノム転写制御の新展開 (2010)
  • Author(s): 石浜明
  • Organizer: 第9回微生物研究会
  • Place of Presentation: 法政大学小金井キャンパス
  • Year and Date: 2010-06-26
• [Presentation] バイオフィルム形成統括制御遺伝子csgDの多因子による転写制御機構 (2010)
  • Author(s): 小笠原寛
  • Organizer: 第7回21世紀大腸菌研究会
  • Place of Presentation: グリーンピア南阿蘇
  • Year and Date: 2010-06-26
• [Presentation] 単一細胞計測システムによる大腸菌プロモーター強度と制御の解析 (2010)
  • Author(s): 寺本潤
  • Organizer: 第9回微生物研究会
  • Place of Presentation: 法政大学小金井キャンパス
  • Year and Date: 2010-06-26
• [Presentation] 桿菌の形態形成に関わる細胞骨格蛋白RodZのRMA結合活性を介した赤痢菌病原因子発現への関与 (2010)
  • Author(s): 三戸部治郎
  • Organizer: 第9回微生物研究会
  • Place of Presentation: 法政大学小金井キャンパス
  • Year and Date: 2010-06-26
• [Presentation] Genome-wide Genomic-SELEX Search of Regulation Targets by Transcription Factors (2010)
  • Author(s): Shimada, T., Fujita, N., Yamamoto, K. and Ishihama, A.
  • Organizer: Jacques Monod Commemorative Minisymposium : Gene Expression and Signalling in Bacteria
  • Place of Presentation: Institut Pasteur, Paris, France
  • Year and Date: 2010-05-31
• [Presentation] Genome-wide Genomic-SELEX Search of Regulation Targets by Transcription Factors. (2010)
  • Author(s): Tomohiro SHIMADA
  • Organizer: Jacques Monod Commemorative Minisymposium
  • Place of Presentation: Institut Pasteur, Paris
  • Year and Date: 2010-05-31
• [Presentation] Prokaryotic Genome Regulation : Multi-factor promoters, multi-target regulators and multi-factor networks. (2010)
  • Author(s): Akira ISHIHAMA
  • Organizer: Japan-India Collaborative Science Program Seminar
  • Place of Presentation: Centre for Cellular and Molecular Biology (CCMB), India
  • Year and Date: 2010-04-17
• [Presentation] Prokaryotic Genome Regulation : Multi-factor promoters, multi-target regulators and multi-factor networks. (2010)
  • Author(s): Akira ISHIHAMA
  • Organizer: Japan-India Collaborative Science Program Seminar
  • Place of Presentation: Centre for DNA Fingerprinting and Diagnosis (CDFD), India
  • Year and Date: 2010-04-16
• [Presentation] Prokaryotic Genome Regulation. Japan-India Collaborative Science Program Seminar (2010)
  • Author(s): Ishihama, A.
  • Organizer: Centre for Cellular and Molecular Biology(CCMB)
  • Place of Presentation: Hyderabad, India
  • Year and Date: 2010-03-17
• [Presentation] Prokaryotic Genome Regulation : Multi-factor promoters, multi-target regulators and multi-factor networks. (2010)
  • Author(s): Ishihama, A.
  • Organizer: Japan-India Collaborative Science Program Seminar
  • Place of Presentation: CCMB, Hyderabad (India)
  • Year and Date: 2010-03-17
• [Presentation] Prokaryotic Genome Regulation : Multi-factor promoters, multi-target regulators and multi-factor networks. (2010)
  • Author(s): Ishihama, A.
  • Organizer: Japan-India Collaborative Science Program Seminar
  • Place of Presentation: CDFD, Hyderabad (India)
  • Year and Date: 2010-03-16
• [Presentation] 大腸菌新規核様体タンパクDanの発見と構造機能解析 (2010)
  • Author(s): 寺本潤・吉村成弘・山田佳代子・郡彩子・竹安邦夫・石浜明
  • Organizer: 特定領域研究「バイオ操作」第8回公開シンポジウム
  • Place of Presentation: 九州大学(福岡)
  • Year and Date: 2010-03-11
• [Presentation] 細菌単一細胞での転写制御の解析 (2010)
  • Author(s): 寺本潤・山西陽子・大山晃太郎・中島正博・新井史人・福田敏男・石浜明
  • Organizer: 特定領域研究「バイオ操作」第8回公開シンポジウム
  • Place of Presentation: 九州大学(福岡)
  • Year and Date: 2010-03-11
• [Presentation] 細菌ゲノム制御全体像解明のための戦略戦術 (2010)
  • Author(s): 石浜明
  • Organizer: 日本大学学術研究高度化推進事業公開シンポジウム
  • Place of Presentation: 日大・オープンリサーチセンター
  • Year and Date: 2010-02-26
• [Presentation] 細菌ゲノム制御全体像解明のための戦略戦術 (2010)
  • Author(s): 石浜明
  • Organizer: 日本大学学術研究高度化推進事業公開シンポジウム「病原体抑制遺伝子の解明と感染症の制御」
  • Place of Presentation: 日本大学(東京)
  • Year and Date: 2010-02-26
• [Presentation] 細菌細胞の個性:その分子基盤 (2010)
  • Author(s): 石浜明
  • Organizer: 九州大学G-COE「未来分子システム科学」公開セミナー
  • Place of Presentation: 九州大学(福岡)
  • Year and Date: 2010-02-09
• [Presentation] Prokaryotic Genome Regulation : Multi-factor Promoters and Multi-target Regulators (2010)
  • Author(s): Ishihama, A.
  • Organizer: 11^<th> Asian Conference on Transcription(ACT)
  • Place of Presentation: Nakijin Hall, Okinawa, Japan
• [Presentation] Prokaryotic Genome Regulation : Multi-factor Promoters and Multi-target Regulators (2010)
  • Author(s): Ishihama, A.
  • Organizer: 2^<nd> Florence Conference on Phenotype Microarray
  • Place of Presentation: Internatl. Conf. Hall, Pisa, Italy
• [Presentation] Multi-scale molecular genetics of prokaryotic genome regulation (2010)
  • Author(s): Ishihama, A., Ogasawara, H., Shimada, T. Teramoto, T., Kori, A., Yamada, K., Kobayashi, K., Katayama, T. and Yamamoto, K.
  • Organizer: 21st Internatl. Symp. Micro-NanoMechatronics Human Sci.
  • Place of Presentation: Nagoya Univ., Nagoya, Japan
• [Presentation] Prokaryotic Genome Regulation : Multi-factor Promoters and Multi-target Regulators. (2010)
  • Author(s): Akira ISHIHAMA
  • Organizer: 11^<th> Asian Conference on Transcription (ACT)
  • Place of Presentation: Okinawa, Japan
• [Presentation] Multi-scale molecular genetics of prokaryotic genome regulation. (2010)
  • Author(s): Akira ISHIHAMA
  • Organizer: 21st Internatl.Symp."Systems Cell Engineering by Multi-scale Manipulation"
  • Place of Presentation: Nagoya, Japan
• [Presentation] Prokaryotic Genome Regulation : Multi-factor Promoters and Multi-target Regulators. (2010)
  • Author(s): Akira ISHIHAMA
  • Organizer: 2^<nd> Flurence Conference on Phenotype Microarray
  • Place of Presentation: Pisa, Italy
• [Presentation] Novel nucleoid protein Dan of Escherichia coli induced under anaerobiotic growth conditions. (2010)
  • Author(s): Jun TERAMOTO
  • Organizer: 21st Internatl.Symp."Systems Cell Engineering by Multi-scale Manipulation"
  • Place of Presentation: Nagoya, Japan
• [Presentation] 核様体タンパク質FisとDpsによるDNA折り畳み様式の差異 (2010)
  • Author(s): 佐藤祐子
  • Organizer: 第48回日本生物物理学会年会
  • Place of Presentation: 東北大川内キャンパス
• [Presentation] Genomic SELEX法を用いた機能未知転写因子YbjKの機能解析 (2010)
  • Author(s): 片山泰徳
  • Organizer: 第4回日本ゲノム微生物学会若手の会
  • Place of Presentation: 神戸セミナーハウス
• [Presentation] Genomic SELEXによる転写因子標的の網羅的探索 (2010)
  • Author(s): 島田友裕
  • Organizer: 第4回日本ゲノム微生物学会若手の会
  • Place of Presentation: 神戸セミナーハウス
• [Presentation] 細菌-細胞観測システムの構築と転写制御解析 (2010)
  • Author(s): 寺本潤
  • Organizer: 第4回日本ゲノム微生物学会若手の会
  • Place of Presentation: 神戸セミナーハウス
• [Presentation] 大腸菌炭素源代謝制御のふたつの転写因子CRPとCraによるゲノム転写制御の全体像:Genomic SELEX法を用いた解析 (2010)
  • Author(s): 島田友裕
  • Organizer: 第33回日本分子生物学会・第83回日本生化学会合同大会
  • Place of Presentation: 神戸ポートアイランド
• [Presentation] 大腸菌機能未知転写因子YcjZの制御機能解析 (2010)
  • Author(s): 山崎薫
  • Organizer: 第33回日本分子生物学会第83回日本生化学会合同大会
  • Place of Presentation: 神戸ポートアイランド
• [Presentation] バイオフィルム形成統括制御遺伝子csgDの多種類転写因子による転写制御機構 (2010)
  • Author(s): 小笠原寛
  • Organizer: 第33回日本分子生物学会・第83回日本生化学会合同大会
  • Place of Presentation: 神戸ポートアイランド
• [Presentation] Fe(III)に応答する大腸菌転写因子BasRの転写制御ネットワークの解明 (2010)
  • Author(s): 篠原翔太
  • Organizer: 第33回日本分子生物学会・第83回日本生化学会合同大会
  • Place of Presentation: 神戸ポートアイランド
• [Presentation] 大腸菌機能未知転写因子YbjKの制御的遺伝子群の同定と制御機能解析 (2010)
  • Author(s): 片山泰徳
  • Organizer: 第33回日本分子生物学会・第83回日本生化学会合同大会
  • Place of Presentation: 袖戸ポートアイランド
• [Presentation] 大腸菌機能未知転写因子YeaMの標的遺伝子の同定と制御機能の解明 (2010)
  • Author(s): 大江星菜
  • Organizer: 第33回日本分子生物学会・第83回日本生化学会合同大会
  • Place of Presentation: 神戸ポートアイランド
• [Presentation] 細胞隔壁制御因子SdiAの新規標的遺伝子群の探索とQSシグナル感知機構の解析 (2010)
  • Author(s): 島田佳織
  • Organizer: 第33回日本分子生物学会・第83回日本生化学会合同大会
  • Place of Presentation: 神戸ポートアイランド
• [Presentation] 大腸菌外来性機能未知遺伝子YagIの制御標的遺伝子群の探索 (2010)
  • Author(s): 籾山絵里
  • Organizer: 第33回日本分子生物学会・第83回日本生化学会合同大会
  • Place of Presentation: 紳戸ポートアイランド
• [Presentation] Identification of novel regulation targets of the antioxidant OxyR transcription factor in Escherichia coll. (2010)
  • Author(s): Jun TERAMOTO
  • Organizer: 第33回日本分子生物学会・第83回日本生化学会合同大会
  • Place of Presentation: 神戸ポートアイランド
• [Presentation] 紫外線によって誘導される大腸菌YdeOの機能解析 (2010)
  • Author(s): 山中幸
  • Organizer: 第33回日本分子生物学会・第83回日本生化学会合同大会
  • Place of Presentation: 神戸ポートアイランド
• [Presentation] 大腸菌機能未知転写因子YkgDの制御標的遺伝子群の同定と機能解析 (2010)
  • Author(s): 大貫章吾
  • Organizer: 第33回日本分子生物学会・第83回日本生化学会合同大会
  • Place of Presentation: 神戸ポートアイランド
• [Presentation] 大腸菌モデル環境における、増殖期と定常期のDNA高次構造変化-ヌクレオイドプロテインFisとDpsによるDNAの折り畳み、その顕著な差異 (2010)
  • Author(s): 佐藤祐子
  • Organizer: 第33回日本分子生物学会・第83回日本生化学会合同大会
  • Place of Presentation: 神戸ポートアイランド
• [Presentation] 多様な環境要因に応答するcsgDプロモーターの転写制御に関わる分子機構の解明 (2010)
  • Author(s): 小笠原寛・郡彩子・山田佳代子・山本兼由・石浜明
  • Organizer: 日本農芸化学会2010大会
  • Place of Presentation: 東京大学(東京)
• [Presentation] 大腸菌転写因子CRPのゲノム上結合部位の全体像:Genomic SELEX法を用いた解析 (2010)
  • Author(s): 島田友裕, 藤田信之, 山本兼由, 石浜明
  • Organizer: 第4回ゲノム微生物学会年会
  • Place of Presentation: 九州大学(福岡)
• [Presentation] モリブデンを感知する転写因子ModEに制御される新規非翻訳RNA (2009)
  • Author(s): 平松優和・小笠原寛・石浜明・山本兼由
  • Organizer: 第8回 微生物研究会
  • Place of Presentation: 日本大学湘南キャンパス(神奈川)
  • Year and Date: 2009-05-30
• [Presentation] Genomic SELEX search for regulation targets by 100 species of uncharacterized transcription factors from E. coli (2009)
  • Author(s): Ishihama, A.
  • Organizer: 12^<th> Transcription Assembly
  • Place of Presentation: Chandigarh, India
• [Presentation] Growth phase-dependent regulation of csgD, the master regulator of biofilm formation (2009)
  • Author(s): Ishihama, A., Ogasawara, H., Shimada, T., Teramoto, J., Kori, A., Yamada, K., and Yamamoto, K.
  • Organizer: 3^<rd> Internatl. Conf. Environmental, Industrial and Applied Microbiology, BioMicroWorld
  • Place of Presentation: Lisbon, Portugal
• [Presentation] Regulatory roles of nucleoid-associated proteins in Escherichia coli (2009)
  • Author(s): Ishihama, A., Teramoto, J., Ogasawara, H., Shimada, T. and Yamamoto, K.
  • Organizer: 32nd Ann. Meet. Mol. Biol. Soc. Jpn
  • Place of Presentation: Pacifico Yokohama, Japan
• [Presentation] 大腸菌ゲノム転写の包括制御 (2009)
  • Author(s): 石浜明
  • Organizer: 2008年度「べん毛研究交流会」
  • Place of Presentation: 秋保グランドホテル、宮城
• [Presentation] 細菌の環境金属応答のゲノム制御 (2009)
  • Author(s): 石浜明, 小笠原寛、島田友祐、寺本潤
  • Organizer: メタロチオネインおよびメタルバイオサイエンス研究会2009
  • Place of Presentation: 東京大学・山上会館
• [Presentation] 大腸菌における環境金属応答のゲノム転写制御 (2009)
  • Author(s): 石浜明
  • Organizer: メタルバイオサイエンス研究会2009
  • Place of Presentation: 東京大学、東京
• [Presentation] 細菌の生存戦略としてのバイオフィルム形成:遺伝子制御ネットワークと転写因子群 (2009)
  • Author(s): 石浜明
  • Organizer: 日本生化学会第82回大会シンポジウム"細菌の生存戦略をめぐる新たな展開"
  • Place of Presentation: 神戸ポートアイランド、神戸
• [Presentation] Genomic SELEX search for regulation targets by 100 species of uncharacterized transcription factors from E.coli. (2009)
  • Author(s): Ishihama, A.
  • Organizer: 12^<th> Transcription Assembly
  • Place of Presentation: Chandigarh (India)
• [Presentation] Growth phase-dependent regulation of csgD, the master regulator of biofilm formation : Interplay between multiple transcription factors. (2009)
  • Author(s): Ishihama, A., Ogasawara, H., Shimada, T., Teramoto, J., Kori, A., Yamada, K., Yamamoto, K.
  • Organizer: 3^<rd> Internatl.Conf.Environ.Indust.Appl. Microbiol. (BioMicroWorld2009)
  • Place of Presentation: Lisbon (Portugal)
• [Presentation] Regulatory roles of nucleoid-associated proteins in Escherichia coli. (2009)
  • Author(s): Ishihama, A., Teramoto, J., Ogasawara, H., Shimada, T., Yamamoto, K.
  • Organizer: 32^<nd> Ann.Meet.Mol.Biol.Soc. Japan
  • Place of Presentation: Pacifico Yokohama (Japan)
• [Presentation] Control of biofilm formation by Escherichia coli : Interplay between multiple transcription factors. (2009)
  • Author(s): Ogasawara, H., Kon, A., Yamada, K., Yamamoto, K., Ishihama, A.
  • Organizer: 20^<th> Internatl.Symp. Micro-NanoMechatronics Human Sci., Symp. "Systems Cell Engineering by Multi-scale Manipulation"
  • Place of Presentation: Nagoya, Univ. (Japan)
• [Presentation] Novel technologies for the genome-wide search of regulation targets by transcription factors : Genomic SELEX and SELEX-chip. (2009)
  • Author(s): Shimada, T., Fujita, N., Yamamoto, K., Ishihama, A.
  • Organizer: 20th Internatl. Symp. Micro-NanoMechatronics Human Sci., Symp. "Systems Cell Engineering by Multi-scale Manipulation"
  • Place of Presentation: Nagoya Unv. (Japan)
• [Presentation] Single live-bacterial cell assay of promoter activity and regulation : Escherichia coli gcl promoter. (2009)
  • Author(s): Teramoto, J., Yamanishi, Y., Magdy, E-S.H., Hasegawa, A., Nakajima, M., Arai, F., Fukuda, T., Ishihama, A.
  • Organizer: 3^<rd> Internatl.Conf.Environ.Indust.Appl.Microbiol. (BioMicroWorld2009)
  • Place of Presentation: Lisbon (Portugal)
• [Presentation] Anaeoboriosis-induced novel nucleoid protein Dan in Escherichia coli. (2009)
  • Author(s): Teramoto, J., Yoshimura, S.H., Takeyasu, K., Ishihama, A.
  • Organizer: 20^<th> Internatl.Symp. Micro-NanoMechatronics Human Sci., Symp. "Systems Cell Engineering by Multi-scale Manipulation"
  • Place of Presentation: Nagoya Univ. (Japan)
• [Presentation] Single live-cell cell assay of promoter activity and regulation. (2009)
  • Author(s): Teramoto, J., Yamanishi, Y., Magdy, E-S.H., Hasegawa, A., Shohata, E., Kori, A., Nakajima, M., Arai, F., Fukuda, T., Ishihama, A.
  • Organizer: 20^<th> Internatl.Symp.Micro-NanoMechatronics Human Sci., Symp. "Systems Cell Engineering by Multi-scale Manipulation"
  • Place of Presentation: Nagoya Univ. (Japan)
• [Presentation] A single cell immobilization and culture system under suspenced polymeric microbridge with compartments. (2009)
  • Author(s): Yamanishi, Y., Teramoto, J., Magariyama, Y., Ishihama, A., Fukuda, T., Arai, F.
  • Organizer: 20^<th> Internatl.Symp.Micro-NanoMechatronics Human Sci., Symp. "Systems Cell Engineering by Multi-scale Manipulation"
  • Place of Presentation: Nagoya Univ. (Japan)
• [Presentation] On-chip temperature control under suspended microbridge for cell immobilization and culture system.A (2009)
  • Author(s): Yamanishi, Y., Teramoto, J., Magariyama, Y., Ishihama, A., Fukuda, T., Arai, F.
  • Organizer: 3^<th> Internatl.Conf. Miniaturized Systems for Chemist.Life Sci. (mTAS)
  • Place of Presentation: Jeju (Korea)
• [Presentation] 細菌の生存戦略としてのバイオフィルム形成:遺伝子制御ネットワークと転写因子群 (2009)
  • Author(s): 石浜明
  • Organizer: 2008年度「べん毛研究会」
  • Place of Presentation: 秋保グランドホテル(宮城)
• [Presentation] 細菌の環境金属応答のゲノム制御 (2009)
  • Author(s): 石浜明・小笠原寛・島田友祐・寺本潤・小林尚貴・郡彩子・山田佳代子・山本兼由
  • Organizer: メタロチオネインおよびメタルバイオサイエンス研究会2009
  • Place of Presentation: 東京大学(東京)
• [Presentation] 細菌の生存戦略としてのバイオフィルム形成:遺伝子制御ネットワークと転写因子群 (2009)
  • Author(s): 石浜明・小笠原寛・島田友祐・寺本潤・小林尚貴・郡彩子・山田佳代子・山本兼由
  • Organizer: 第82回日本生化学会大会シンポジウム「細菌の生存戦略をめぐる新たな展開」
  • Place of Presentation: 神戸ポートピア(神戸)
• [Presentation] 大腸菌転写因子YpdB支配下制御遺伝子群の同定と制御機構の解明 (2009)
  • Author(s): 稲葉達也・山田佳代子・郡彩子・石浜明
  • Organizer: 日本ゲノム微生物学会第3回年会
  • Place of Presentation: 中央大学(東京)
• [Presentation] 大腸菌機能未知転写因子YkgDの制御標的遺伝子群の同定と機能解析 (2009)
  • Author(s): 大貫章吾・寺本潤・郡彩子・石浜明
  • Organizer: 第32回日本分子生物学会年会
  • Place of Presentation: パシフィコ横浜(横浜)
• [Presentation] 細胞分裂調節因子SdiAに影響するHomoserine Lactone類似体の同定と新規支配下遺伝子群の探索 (2009)
  • Author(s): 島田佳織・鍛代悠一・松井誠・島田友裕・五十嵐潤・菅裕明・石浜明
  • Organizer: 第32回日本分子生物学会年会
  • Place of Presentation: パシフィコ横浜(横浜)
• [Presentation] ウラシル/チミンを感知する転写因子RutRによるピリミジン合成/分解経路に関与する遺伝子群の制御機構の解析 (2009)
  • Author(s): 島田友祐・山本兼由・石浜明
  • Organizer: 日本農芸化学会2009年度大会
  • Place of Presentation: 福岡メッセ(福岡)
• [Presentation] Genomic SELEXを用いた大腸菌LeuOの転写制御機構解析 (2009)
  • Author(s): 島田友祐・山本兼由・石浜明
  • Organizer: 第6回 21世紀大腸菌研究会
  • Place of Presentation: KKR熱海(神奈川)
• [Presentation] Genomic SELEXを用いた大腸菌LeuOの転写制御機構解析 (2009)
  • Author(s): 島田友裕・山本兼由・石浜明
  • Organizer: 日本ゲノム微生物学会第3回年会
  • Place of Presentation: 中央大学(東京)
• [Presentation] Involvement of the leucine response transcription factor LeuO in regulation of the genes for sulfa drug efflux. (2009)
  • Author(s): 島田友裕・山本兼由・石浜明
  • Organizer: 第32回日本分子生物学会年会
  • Place of Presentation: パシフィコ横浜(横浜)
• [Presentation] ビフィズス菌の共存時に発現する大腸菌プロモーター (2009)
  • Author(s): 田村正典・村田侑子・森田英利・石浜明・山本兼由
  • Organizer: 第6回 21世紀大腸菌研究会
  • Place of Presentation: KKR熱海(神奈川)
• [Presentation] Identification of promoters induced in Escherichia coli growing with Bifidobacterium. (2009)
  • Author(s): 田村正典・村田侑子・石浜明・山本兼由
  • Organizer: 第32回日本分子生物学会年会
  • Place of Presentation: パシフィコ横浜(横浜)
• [Presentation] 多因子が関与する大腸菌Curli線毛発現制御機構の解明 (2009)
  • Author(s): 小笠原寛・郡彩子・山田佳代子・山本兼由・石浜明
  • Organizer: 日本農芸化学会2009年度大会
  • Place of Presentation: 福岡メッセ(福岡)
• [Presentation] Control of biofilm formation by Escherichia coli : Interplay between multiple transcription factors. (2009)
  • Author(s): 小笠原寛・郡彩子・山田佳代子・山本兼由・石浜明
  • Organizer: 第32回日本分子生物学会年会
  • Place of Presentation: パシフィコ横浜(横浜)
• [Presentation] 大腸菌機能未知転写因子YidZの制御楳的遺伝子群の同定と制御機能解析 (2009)
  • Author(s): 片山泰徳・小笠原寛・郡彩子・山田佳代子・石浜明
  • Organizer: 第32回日本分子生物学会年会
  • Place of Presentation: パシフィコ横浜(横浜)
• [Presentation] 大腸菌機能未知転写因子YbjKによる転写制御機構の解析 (2009)
  • Author(s): 河北寿一・島田友裕・山田佳代子・石浜明
  • Organizer: 第32回日本分子生物学会年会
  • Place of Presentation: パシフィコ横浜(横浜)
• [Presentation] 大腸菌機能未知転写因子YneJによる転写制御機構の解析 (2009)
  • Author(s): 國友雄介・寺本潤・山田佳代子・長谷川明子・石浜明
  • Organizer: 第32回日本分子生物学会年会.
  • Place of Presentation: パシフィコ横浜(横浜)
• [Presentation] Quorum Sensing転写因子QseAの調節機能の解析 (2009)
  • Author(s): 小林尚貴・寺本潤・石浜明
  • Organizer: 日本ゲノム微生物学会第3回年会
  • Place of Presentation: 中央大学(東京)
• [Presentation] Quorum-sensing transcription factor QseA of Escherichia coli : Search for regulation targets and analysis of reaulatorv modes. (2009)
  • Author(s): 小林尚貴・稲葉達也・山田佳代子・寺本潤・石浜明
  • Organizer: 第32回日本分子生物学会年会
  • Place of Presentation: パシフィコ横浜(横浜)
• [Presentation] 嫌気条件で誘導される大腸菌新規核様体タンパク質 (2009)
  • Author(s): 寺本潤・吉村成弘・竹安邦夫・石浜明
  • Organizer: 第6回 21世紀大腸菌研究会
  • Place of Presentation: KKR熱海(神奈川)
• [Presentation] Single live-bacterial cell assay of promoter activity and regulation in Escherichia coli. (2009)
  • Author(s): 寺本潤・山西陽子・Magdy, E-S.H.・長谷川明子・正畑絵理・新井史人・福田敏男・石浜明
  • Organizer: 第32回日本分子生物学会年会
  • Place of Presentation: パシフィコ横浜(横浜)
• [Presentation] 大腸菌転写因子DeoRの新規標的遺伝子群の同定と制御機能解明 (2009)
  • Author(s): 中川史之・島田友裕・石田雄士・石浜明
  • Organizer: 第32回日本分子生物学会年会
  • Place of Presentation: パシフィコ横浜(横浜)
• [Presentation] 大腸菌全tRNA遺伝子発現プロファイルの解析 (2009)
  • Author(s): 長谷川喬彬・梅林章・石浜明・前田理久
  • Organizer: 第32回日本分子生物学会年会
  • Place of Presentation: パシフィコ横浜(横浜)
• [Presentation] Novel non-coding RNA regulated by ModE in Escherichia coli. (2009)
  • Author(s): 平松優和・小笠原寛・石浜明・山本兼由
  • Organizer: 第32回日本分子生物学会年会
  • Place of Presentation: パシフィコ横浜(横浜)
• [Presentation] モリブデンを感知する転写因子ModEに制御される新規非翻訳RNA (2009)
  • Author(s): 平松優和・小笠原寛・石浜明・山本兼由
  • Organizer: 第82回日本生化学会大会
  • Place of Presentation: 神戸ポートピア(神戸)
• [Presentation] Autoregulation of the murR repressor that regulate the enzymes for the degradation of N-acetylymuramic acid in Escherichia coli. (2009)
  • Author(s): 山本兼由・石浜明
  • Organizer: 第32回日本分子生物学会年会
  • Place of Presentation: パシフィコ横浜(横浜)
• [Book] Detection of bacterial bahits : Single planktonic cells and assembled Detection of bacterial bahits : Single planktonic cells and assembled biofilm. In : Nanomedicine in Diagnostics (2012)
  • Author(s): Ishihama, A.
  • Publisher: Science Publishes
• [Book] Transcription factors and transcriptional apparatus in bacteria. In : Encyclopedia of Systems Biology (2012)
  • Author(s): Ishihama, A.
  • Publisher: Springer
• [Book] Encyclopedia of Systems Biology (2012)
  • Author(s): Ishihama, A.
  • Publisher: Springer, London, UK(In press)
• [Book] Nanomedicine in Diagnostics (2012)
  • Author(s): Ishihama, A.
  • Publisher: CRC Press, Boca Raton, FL, USA(In press)
• [Book] Prokaryotic genome regulation : Multi-factor promoters, multi-target regulators and hierarchic networks (2010)
  • Author(s): Ishihama, A.
• [Book] Chapter 2.6, The Nucleoid : an Overview. In : EcoSal. Escherichia coli and Salmonella : cellular and molecular biology (2010)
  • Author(s): Ishihama, A.
  • Publisher: インターネット出版
  • URL: http://www.ecosal.org.
• [Book] 原核生物RNAポリメラーゼ.「生化学事典」 (2010)
  • Author(s): 石浜明
  • Total Pages: 788
  • Publisher: 朝倉書店
• [Book] EcoSal-Escherichia coil and Salmonella : Cellular and Molecular Biology (Chapter 2:6: The Nucleoid : an Overview) (2010)
  • Author(s): Ishihama, A.
  • Total Pages: 2000
  • Publisher: ASM (American Society for Microbiology) Press
• [Book] EcoSal-Escherichia coli and Salmonella : cellular and molecular biology. (2009)
  • Author(s): Ishihama, A.
  • Publisher: ASM (American Society for Microbiology) Press