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Visual Servo Microscope for Analysis of Animal Behavior

Research Project

Project/Area Number 21246040
Research Category

Grant-in-Aid for Scientific Research (A)

Allocation TypeSingle-year Grants
Section一般
Research Field Intelligent mechanics/Mechanical systems
Research InstitutionTohoku University

Principal Investigator

KOICHI Hashimoto  東北大学, 大学院・情報科学研究科, 教授 (80228410)

Project Period (FY) 2009 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥46,280,000 (Direct Cost: ¥35,600,000、Indirect Cost: ¥10,680,000)
Fiscal Year 2012: ¥6,500,000 (Direct Cost: ¥5,000,000、Indirect Cost: ¥1,500,000)
Fiscal Year 2011: ¥6,500,000 (Direct Cost: ¥5,000,000、Indirect Cost: ¥1,500,000)
Fiscal Year 2010: ¥12,350,000 (Direct Cost: ¥9,500,000、Indirect Cost: ¥2,850,000)
Fiscal Year 2009: ¥20,930,000 (Direct Cost: ¥16,100,000、Indirect Cost: ¥4,830,000)
Keywords情報機器 / 知能機械システム / ビジュアルサーボ / トラッキング顕微鏡 / オプトジェネティクス / 線虫 / ゼブラフィッシュ / 高速画像処理 / 蛍光顕微鏡 / 3D / 神経ネットワーク / ロックオントラッキング顕微鏡 / 蛍光観察 / 画像処理 / 行動解析
Research Abstract

We have developed a microscope system that tracks a target animal motion by using real-time control of motorized stage. The system can analyze and record the response of the target animal with high time and space resolutions. Especially, we have realized a system to observe C. elegans in bright field as well as in fluorescence images simultaneously. C. elegans is widely used for many purpose as a model animal. Thus the system is contributing in many fields including sensor response, neural network analysis, internal neural state analysis, motor control, and also animal behavior.

Report

(5 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • 2009 Annual Research Report
  • Research Products

    (30 results)

All 2012 2011 2009 Other

All Journal Article (9 results) (of which Peer Reviewed: 9 results) Presentation (20 results) (of which Invited: 1 results) Remarks (1 results)

  • [Journal Article] Estimating Deformation of Neurons in Fluorescent Images2012

    • Author(s)
      Fei, X., Teramoto, T., Ishihara, T. and Hashimoto, K.
    • Journal Title

      Interdisciplinary Information Sciences

      Volume: 18 Issue: 2 Pages: 113-122

    • DOI

      10.4036/iis.2012.113

    • NAID

      130002531672

    • ISSN
      1340-9050, 1347-6157
    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] GPU Acceleration in a Visual Servo System2012

    • Author(s)
      Chuantao Zang, Koichi Hashimoto
    • Journal Title

      Journal of Robotics and Mechatronics

      Volume: 24 Pages: 105-114

    • NAID

      110009957683

    • Related Report
      2011 Annual Research Report 2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Stability of switched stochastic systems in discrete-time2011

    • Author(s)
      Iwatani, Y., Arai, S. and Hashimoto, K.
    • Journal Title

      SICE Journal of Control, Measurement, and System Integration

      Volume: 3(5) Pages: 368-371

    • NAID

      10031140029

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] A condition for better estimation using asynchronous sampling than synchronous sampling2011

    • Author(s)
      Arai, S., Iwatani, Y. and Hashimoto, K.
    • Journal Title

      SICE Journal of Control, Measurement, and System Integration

      Volume: 4(3) Pages: 249-253

    • NAID

      10031140078

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] 細胞の個体差に適応する高速オートフォーカス顕微鏡2011

    • Author(s)
      小原健, 五十嵐康伸, 橋本浩一
    • Journal Title

      計測自動制御学会論文集

      Volume: 47(1) Pages: 31-39

    • NAID

      10027787549

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Fast Sensor Scheduling for Spatially Distributed Sensors2011

    • Author(s)
      Arai, S., Iwatani Y. and Hashimoto, K.
    • Journal Title

      IEEE Transactions on Automatic Control

      Volume: 56(8) Issue: 8 Pages: 1900-1905

    • DOI

      10.1109/tac.2011.2141450

    • Related Report
      2012 Final Research Report 2011 Annual Research Report 2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 細胞の個体差に適応する高速オートフォーカス顕微鏡2011

    • Author(s)
      小原健、五十嵐康伸、橋本浩一
    • Journal Title

      計測自動制御学会論文集

      Volume: 47 Pages: 31-39

    • NAID

      10027787549

    • Related Report
      2011 Annual Research Report 2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A Parallel Computation of the Region-Based Level Set Method for Boundary Detection with Moving Objects2009

    • Author(s)
      Fei, X., Igarashi, Y., Shinkai, M., Ishikawa, M. and Hashimoto, K.
    • Journal Title

      Journal of Robotics and Mechatronics

      Volume: 21 Pages: 698-708

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] A Parallel Computation of the Region-Based Level Set Method for Boundary Detection with Moving Objects2009

    • Author(s)
      X.Fei
    • Journal Title

      Journal of Robotics and Mechatronics 21

      Pages: 698-708

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Presentation] Exploration of Brain Function through Behavior2012

    • Author(s)
      Hashimoto, K. and Fei, X.
    • Organizer
      Neural Activity Observation, and Optogenetic Manipulation. Invited Talk, International Symposium Optomechatronic Technologies (ISOT 2012)
    • Place of Presentation
      France
    • Year and Date
      2012-09-29
    • Related Report
      2012 Final Research Report
  • [Presentation] A virtual reality running machine for worms-a highly integrated system for olfactory behavior2012

    • Author(s)
      Tanimoto, Y., Yamazoe, A., Hashimoto, K. and Kimura, K.
    • Organizer
      5th East Asia C. elegans Meeting, 4-O06
    • Place of Presentation
      Taipei, Taiwan
    • Year and Date
      2012-06-30
    • Related Report
      2012 Final Research Report
  • [Presentation] Neurite fluorescence imaging of freely moving individual C. elegans animals with high-speed tracking and autofocus system2012

    • Author(s)
      Yokoyama, G., Tsukada, Y., Chen, M., Hashimoto, K. and Mori, I.
    • Organizer
      5th East Asia C. elegans Meeting, P-56
    • Place of Presentation
      Taipei, Taiwan
    • Year and Date
      2012-06-30
    • Related Report
      2012 Final Research Report
  • [Presentation] A virtual reality running machine for worms-a highly integrated system for olfactory behavior2012

    • Author(s)
      Tanimoto, Y., Yamazoe, A., Hashimoto, K. and Kimura, K.
    • Organizer
      EMBL Conference C. elegans Neurobiology, P-126
    • Place of Presentation
      Heidelberg, Germany
    • Year and Date
      2012-06-17
    • Related Report
      2012 Final Research Report
  • [Presentation] High-speed tracking system for neurite fluorescence imaging during freely moving C. elegans.2012

    • Author(s)
      Tsukada, Y., Chen, M., Yokoyama, G., Hashimoto, K. and Mori, I.
    • Organizer
      EMBL Conference C. elegans Neurobiology, P-196
    • Place of Presentation
      Heidelberg, Germany
    • Year and Date
      2012-06-17
    • Related Report
      2012 Final Research Report
  • [Presentation] Exploration of brain function through behavior, neural activity observation, and optogenetic manipulation2012

    • Author(s)
      Hashimoto, K., and Xianfeng Fei
    • Organizer
      2012 International Symposium on Optomechatronic Technologies (ISOT)
    • Place of Presentation
      Paris, France
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] Neurite fluorescence imaging of freely moving individual C. elegans animals with high-speed tracking and autofocus system2012

    • Author(s)
      Genta Yokoyama, Yuki Tsukada, Chen Min, Koichi Hashimoto, Ikue Mori
    • Organizer
      5th East Asia C. elegans Meeting
    • Place of Presentation
      Taipei, Taiwan
    • Related Report
      2012 Annual Research Report
  • [Presentation] High-speed tracking system for neurite fluorescence imaging during freely moving C. elegans2012

    • Author(s)
      Yuki Tsukada, Chen Min, Genta Yokoyama, Koichiro Hashimoto, Ikue Mori
    • Organizer
      EMBO Conference Series: C. elegans Neurobiology
    • Place of Presentation
      Heidelberg, Germany
    • Related Report
      2012 Annual Research Report
  • [Presentation] A virtual reality running machine for worms - a highly integrated tracking system for olfactory behavior2012

    • Author(s)
      Yuki Tanimoto, Akiko Yamazoe, Koichiro Hashimoto, Kotaro Kimura
    • Organizer
      EMBO Conference Series: C. elegans Neurobiology
    • Place of Presentation
      Heidelberg, Germany
    • Related Report
      2012 Annual Research Report
  • [Presentation] Camera Localization by CAD Model Matching2011

    • Author(s)
      Zang, C. and Hashimoto, K.
    • Organizer
      2011 IEEE/SICE International Symposium on System Integration (SII 2011)
    • Place of Presentation
      Kyoto, Japan
    • Year and Date
      2011-12-20
    • Related Report
      2012 Final Research Report
  • [Presentation] Visual Servo Microscope for Locking on Single Neviron of a Worm2011

    • Author(s)
      Mitsunori Maru, Min Chen, Koichi Hashimoto
    • Organizer
      IEEE Int.Conf.Robotics and Biomimetics
    • Place of Presentation
      Thailand, Phuket
    • Related Report
      2011 Annual Research Report
  • [Presentation] Visual Servo Microscope for Locking on Single Neuron of a Worm2011

    • Author(s)
      Mitsunori Maru, Min Chen, Koichi Hashimoto
    • Organizer
      IEEE Int.Conf.Robotics and Biomimetics
    • Place of Presentation
      Thailand
    • Related Report
      2010 Annual Research Report
  • [Presentation] A Parallel Region-Based LSM with Displacement Correction for Tracking a Single Moving Object2009

    • Author(s)
      X.Fei
    • Organizer
      計測自動制御学会SI部門
    • Place of Presentation
      東京
    • Year and Date
      2009-12-24
    • Related Report
      2009 Annual Research Report
  • [Presentation] 運動する細胞の観察を自動化する顕微鏡システムの開発とその応用2009

    • Author(s)
      小原健
    • Organizer
      計測自動制御学会SI部門
    • Place of Presentation
      東京
    • Year and Date
      2009-12-24
    • Related Report
      2009 Annual Research Report
  • [Presentation] アフィン変換を用いた変形する物体のビジュアルトラッキング2009

    • Author(s)
      遠藤義英
    • Organizer
      計測自動制御学会SI部門
    • Place of Presentation
      東京
    • Year and Date
      2009-12-24
    • Related Report
      2009 Annual Research Report
  • [Presentation] 線虫の特定部位を実時間追跡する顕微鏡システム2009

    • Author(s)
      丸三徳
    • Organizer
      計測自動制御学会SI部門
    • Place of Presentation
      東京
    • Year and Date
      2009-12-24
    • Related Report
      2009 Annual Research Report
  • [Presentation] Parallel computation of level set method for 500Hz visual servo control2009

    • Author(s)
      X.Fei
    • Organizer
      28^<th> International Congress on High-Speed Imaging and Photonics
    • Place of Presentation
      Canberra, AUSTRALIA
    • Year and Date
      2009-11-09
    • Related Report
      2009 Annual Research Report
  • [Presentation] Parallel Region-Based Level Set Method with Displacement Correction for Tracking a Single Moving Object2009

    • Author(s)
      X.Fei
    • Organizer
      Advanced Concepts for Intelligent Vision Systems
    • Place of Presentation
      Bordeaux, FRANCE
    • Year and Date
      2009-09-29
    • Related Report
      2009 Annual Research Report
  • [Presentation] ビジュアルサーボとその生体計測への応用2009

    • Author(s)
      橋本浩一
    • Organizer
      第24回生体・生理工学シンポジウム
    • Place of Presentation
      仙台
    • Year and Date
      2009-09-25
    • Related Report
      2009 Annual Research Report
  • [Presentation] 線虫の追跡を実現する蛍光顕微鏡システム2009

    • Author(s)
      丸三徳
    • Organizer
      日本機械学会
    • Place of Presentation
      福岡
    • Year and Date
      2009-05-26
    • Related Report
      2009 Annual Research Report
  • [Remarks] ロックオントラッキング顕微鏡

    • URL

      http://www.ic.is.tohoku.ac.jp/ja/sysbio/

    • Related Report
      2012 Annual Research Report

URL: 

Published: 2009-04-01   Modified: 2019-07-29  

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