| Budget Amount *help |
¥37,050,000 (Direct Cost: ¥28,500,000、Indirect Cost: ¥8,550,000)
Fiscal Year 2012: ¥17,680,000 (Direct Cost: ¥13,600,000、Indirect Cost: ¥4,080,000)
Fiscal Year 2011: ¥12,350,000 (Direct Cost: ¥9,500,000、Indirect Cost: ¥2,850,000)
Fiscal Year 2010: ¥7,020,000 (Direct Cost: ¥5,400,000、Indirect Cost: ¥1,620,000)
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| Research Abstract |
MPF (maturation/M phase-promoting factor) is the universal inducer of M-phase in eukaryotic cells. It is currently accepted that MPF is identical to the kinase cyclin B-Cdk1. Here we show that MPF and cyclin B-Cdk1 are not synonymous, and istead, that MPF is a system consisting of cyclin B-Cdk1 and another kinase, Greatwall kinase.
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