| Project/Area Number |
21248032
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| Research Category |
Grant-in-Aid for Scientific Research (A)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Applied animal science
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| Research Institution | Tohoku University |
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Principal Investigator |
SATO Eimei 東北大学, 大学院・農学研究科, 教授 (80093243)
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| Co-Investigator(Kenkyū-buntansha) |
SHIMADA Masayuki 広島大学, 大学院・生物圏科学研究科, 准教授 (20314742)
HOSHINO Yumi 東北大学, 大学院・農学研究科, 助教 (10451551)
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥47,190,000 (Direct Cost: ¥36,300,000、Indirect Cost: ¥10,890,000)
Fiscal Year 2011: ¥14,560,000 (Direct Cost: ¥11,200,000、Indirect Cost: ¥3,360,000)
Fiscal Year 2010: ¥15,470,000 (Direct Cost: ¥11,900,000、Indirect Cost: ¥3,570,000)
Fiscal Year 2009: ¥17,160,000 (Direct Cost: ¥13,200,000、Indirect Cost: ¥3,960,000)
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| Keywords | 卵子 / 微小器官動態 / IVMFC 技術 / ギャップ結合 / ミトコンドリア / 卵成熟 / 受精能 / 発生能力 / Akt / 紡錘体 / 中心小体周辺物質 / dbcAMP / 体外成熟卵子 / IVMFC技術 / ギャップ結合制御因子 / ミトコンドリア配置制御因子 |
|---|
| Research Abstract |
Improve spectacularly of in vitro maturation (IVM) of an immature oocyte which makes the core of in vitro culture system of oocyte is aimed, it focused on localization, morphology and function of the microtubules (e.g. gap junction, nuclear membrane, chromosome, endoplasmic reticulum, spindle, mitochondria, cortical granule) of an immature oocyte, and identified the control agent. Furthermore, the chemical substance which controls expression of a control agent artificially was searched.
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