Structural elucidation of nucleus and chromosome using non-linear optical microscopy

• Project/Area Number: 21248040
• Research Category: Grant-in-Aid for Scientific Research (A)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Applied molecular and cellular biology
• Research Institution: Osaka University
• Principal Investigator: FUKUI Kiichi 大阪大学, 工学研究科, 教授 (00311770)
• Co-Investigator(Kenkyū-buntansha): OZEKI Yasuyuki 大阪大学, 大学院・工学研究科, 助教 (60437374) ; ITO Kazuyoshi 大阪大学, 大学院・工学研究科, 教授 (80113520) ; UCHIYAMA Susumu 大阪大学, 大学院・工学研究科, 准教授 (90335381)
• Project Period (FY): 2009 – 2012
• Project Status: Completed (Fiscal Year 2012)
• Budget Amount: ¥35,620,000 (Direct Cost: ¥27,400,000、Indirect Cost: ¥8,220,000); Fiscal Year 2012: ¥5,720,000 (Direct Cost: ¥4,400,000、Indirect Cost: ¥1,320,000); Fiscal Year 2011: ¥6,890,000 (Direct Cost: ¥5,300,000、Indirect Cost: ¥1,590,000); Fiscal Year 2010: ¥9,880,000 (Direct Cost: ¥7,600,000、Indirect Cost: ¥2,280,000); Fiscal Year 2009: ¥13,130,000 (Direct Cost: ¥10,100,000、Indirect Cost: ¥3,030,000)
• Keywords: 非線形光学顕微鏡 / 染色体観察 / 低侵襲無染色 3 次元観察 / 誘導パラメトリック発光顕微鏡 / 染色体動態観察 / 無染色可視化 / 低侵襲観察 / 細胞動態観察 / 極短パルスレーザー / ケージド化合物 / 3次元観察

Research Abstract

Non-labeling and 3D visualization of nuclear and chromosomal structures were achieved by using newly developed non-linear optical microscopic techniques, such as Stimulated Raman Scattering(SRS) microscopy and Stimulated Parametric Emission（SPE） microscopy.

Research Products

• [Journal Article] Visualization of Oil Body Distribution in Jatropha curcas L. by Four-Wave Mixing Microscopy (2013)
  • Author(s): Ishii M., Uchiyama S., Ozeki Y., Kajiyama S., Itoh, K. and Fukui K.
  • Journal Title: Jpn. J. Appl. Phys. Volume: Vol 52 Pages: 62403-62407
  • NAID: 40019678278
  • Peer Reviewed
• [Journal Article] Sensitivity enhancement of fiber-laser-based stimulated Raman scattering microscopy by collinear balanced detection technique (2012)
  • Author(s): Nose K., Ozeki Y., Kishi T., Sumimura K., Nishizawa N., Fukui K., Kanematsu Y., and Itoh K.
  • Journal Title: Optics Express Volume: Vol. 20 Pages: 13958-13965
  • Peer Reviewed
• [Journal Article] High-speed molecular spectral imaging of tissue with stimulated Raman scattering (2012)
  • Author(s): Ozeki Y., Umemura W., Otsuka Y., Satoh S., Hashimoto H., Sumimura K., Nishizawa N., Fukui K. and Itoh K.
  • Journal Title: Nature Photonics Volume: Vol.6 Pages: 845-851
  • Peer Reviewed
• [Journal Article] Stimulated Raman hyperspectral imaging based on spectral filtering of broadband laser pulses (2012)
  • Author(s): Ozeki Y., Umemura W., Sumimura K., Nishizawa N., Fukui K., and Itoh K.
  • Journal Title: Optics Letters Volume: Vol. 37 Pages: 431-433
  • Peer Reviewed
• [Journal Article] Subharmonic Synchronization of Picosecond Yb Fiber Laser to Picosecond Ti:Sapphire Laser for Stimulated Raman Scattering Microscopy (2012)
  • Author(s): Umemura W., Fujita K., Ozeki Y., Goto K., Sumimura K., Nishizawa N., Fukui K., Itoh K.
  • Journal Title: Jpn. J. Appl. Phys. Volume: Vol. 51 Pages: 22702-22705
  • NAID: 210000140136
  • Peer Reviewed
• [Journal Article] Sensitivity enhancement of fiber-laser-based stimulated Raman scattering microscopy by collinear balanced detection technique (2012)
  • Author(s): Keisuke Nose
  • Journal Title: Optics Express Volume: 20 Issue: 13 Pages: 13958-13965
  • DOI: 10.1364/oe.20.013958
  • Peer Reviewed
• [Journal Article] High-speed molecular spectral imaging of tissue with stimulated Raman scattering (2012)
  • Author(s): Y. Ozeki
  • Journal Title: Nature Photonics Volume: 6 Issue: 12 Pages: 845-851
  • DOI: 10.1038/nphoton.2012.263
  • Peer Reviewed
• [Journal Article] Stimulated Raman hyperspectral imaging based on spectral filtering of broadband laser pulses (2012)
  • Author(s): Y. Ozeki
  • Journal Title: Optics Letters Volume: 37 Pages: 431-433
  • Peer Reviewed
• [Journal Article] Protein encapsulation within synthetic molecular hosts (2012)
  • Author(s): D. Fujita, K. Suzuki, S. Sato, M. Yagi-Utsumi, Y. Yamaguchi, N. Mizuno, T. Kumasaka, M. Takata, M. Noda, S. Uchiyama, K. Kato, and M. Fujita
  • Journal Title: Nature Communications Volume: 3 Issue: 1 Pages: 1093-1093
  • DOI: 10.1038/ncomms2093
  • Peer Reviewed
• [Journal Article] Chromosome observation by scanning electron microscopy using ionic liquid. (2012)
  • Author(s): Dwiranti, A.
  • Journal Title: Microsc. Res. Tech. Volume: 75 Issue: 8 Pages: 1113-1118
  • DOI: 10.1002/jemt.22038
  • Peer Reviewed
• [Journal Article] RBMX: a regulator for maintenance and centromeric protection of sister chromatid cohesion. (2012)
  • Author(s): Matsunaga, S.
  • Journal Title: Cell Rep. Volume: 19 Issue: 4 Pages: 299-308
  • DOI: 10.1016/j.celrep.2012.02.005
  • Peer Reviewed
• [Journal Article] Subharmonic Synchronization of Picosecond Yb Fiber Laser to Picosecond Ti : Sapphire Laser for Stimulated Raman Scattering Microscopy (2012)
  • Author(s): W.Umemura, et.al.
  • Journal Title: Jpn.J.Appl.Phys. Volume: 51 Issue: 2R Pages: 22702-22702
  • DOI: 10.1143/jjap.51.022702
  • Peer Reviewed
• [Journal Article] Stimulated Raman hyperspectral imaging based on spectral filtering of broadband laser pulses (2012)
  • Author(s): Y.Ozeki, et al
  • Journal Title: Opt.Lett. Volume: 37 Issue: 3 Pages: 431-433
  • DOI: 10.1364/ol.37.000431
  • Peer Reviewed
• [Journal Article] The middle region of an HP1-binding protein, HP1-BP74, associates with linker DNA at the entry/exit site of nucleosomal DNA (2010)
  • Author(s): Hayashihara K., Uchiyama S., Shimamoto S., Kobayashi S., Tomschik M., Wakamatsu H., No D., Sugahara H., Hori N., Noda M., Ohkubo T., Zlatanova J., Matsunaga S. and Fukui K.
  • Journal Title: J. Biol. Chem. Volume: Vol. 285 Pages: 6498-6507
  • NAID: 120006995000
  • Peer Reviewed
• [Journal Article] Stimulated Raman scattering microscopy for live cell imaging with high contrast and high sensitivity (2010)
  • Author(s): Ozeki Y. and Itoh K.
  • Journal Title: Laser Phys. Volume: Vol. 20 Pages: 1114-1118
  • Peer Reviewed
• [Journal Article] Dual-Band Stimulated Parametric Emission Microscopy (2010)
  • Author(s): Yamagiwa M., Omura G., Ozeki Y., Ishii M., H. M. Dang, Kajiyama S., Suzuki T., Fukui K., and Itoh K.
  • Journal Title: Jpn. J. Appl. Phys. Volume: Vol. 49 Pages: 16603-16606
  • NAID: 40016941289
  • Peer Reviewed
• [Journal Article] Three-Dimensional Unstained Live-Cell Imaging Using Stimulated Parametric Emission Microscopy (2010)
  • Author(s): H. M. Dang, Kawasumi T., Omura G., Umano T., Kajiyama S., Ozeki Y., Itoh K., and Fukui K.
  • Journal Title: Jpn. J. Appl. Phys. Volume: Vol.48 Pages: 97003-97007
  • NAID: 40016743047
  • Peer Reviewed
• [Journal Article] The middle region of an HP1-binding protein, HP1-BP74, associates with linker DNA at the entry/exit site of nucleosomal DNA (2010)
  • Author(s): Hayashihara K., Uchiyama S., Shimamoto S., Kobayashi S., Tomschik M., Wakamatsu H., No D., Sugahara H., Hori N., Noda M., Ohkubo T., Zlatanova J., Matsunaga S., Fukui K.
  • Journal Title: J Biol Chem. Volume: 285 Pages: 6498-507
  • NAID: 120006995000
  • Peer Reviewed
• [Journal Article] Integration of cytogenetic and genetic linkage maps of Lotus japonicus, a model plant for legumes (2010)
  • Author(s): Ohmido N., Ishimaru A., Kato S., Sato S., Tabata S., Fukui K.
  • Journal Title: Chromosome Res. Volume: 18 Pages: 287-99
  • Peer Reviewed
• [Journal Article] Recent advances in rice genome and chromosome structure re search by fluorescence in situ hybridization (FISH) (2010)
  • Author(s): Ohmido N., Ishimaru A., Kato S., Sato S., Tabata S., Fukui K.
  • Journal Title: Proc.Jpn.Acad.Ser.B.Phys.Biol.Sci. Volume: 86 Pages: 103-116
  • NAID: 130000168767
  • Peer Reviewed
• [Journal Article] Stimulated Raman scattering microscopy for live cell imaging with high contrast and high sensitivity (2010)
  • Author(s): Y.Ozeki, K.Itoh
  • Journal Title: Laser Phys. Volume: 20 Pages: 1114-1118
  • Peer Reviewed
• [Journal Article] Stimulated Raman scattering microscope with shot noise limited sensitivity using subharmonically synchronized laser pulses (2010)
  • Author(s): Y.Ozeki, Y.Kitagawa, K.Sumimura, N.Nishizawa, W.Umemura, S.Kajiyama, K.Fukui, K.Itoh
  • Journal Title: Opt.Express. Volume: 18 Pages: 13708-13719
  • NAID: 120006994999
  • Peer Reviewed
• [Journal Article] Dual-Band Stimulated Parametric Emission Microscopy (2010)
  • Author(s): M.Yamagiwa, G.Omura, Y.Ozeki, M.Ishii, H.M.Dang, S.Kajiyama, T.Suzuki, K.Fukui, K.Itoh
  • Journal Title: Jpn.J.Appl.Phys. 49 Pages: 16603-16606
  • NAID: 40016941289
  • Peer Reviewed
• [Journal Article] Label-free imaging by stimulated parametric emission microscopy reveals a difference in hemoglobin distribution between live and fixed erythrocytes (2009)
  • Author(s): H. M. Dang, Omura G., Umano T., Yamagiwa M., Kajiyama S., Ozeki Y., Itoh K., Fukui K.
  • Journal Title: J. Biomed. Opt. Volume: Vol.14 Pages: 40506-40508
  • NAID: 120006980200
  • Peer Reviewed
• [Journal Article] Three-Dimensional Unstained Live-Cell Imaging Using Stimulated Para metric Emission Microscopy (2009)
  • Author(s): H.M.Dang, T.Kawasumi, G.Omura, T.Umano, S.Kajiyama, Y.Ozeki, K.Itoh, K.Fukui
  • Journal Title: Jpn.J.Appl.Phys. 48 Pages: 97003-97007
  • Peer Reviewed
• [Journal Article] Label-free imaging by stimulated parametric emission microscopy reveals a difference in hemoglobin distribution between live and fixed erythrocytes (2009)
  • Author(s): H.M.Dang, G.Omura, T.Umano, M.Yamagiwa, S.Kajiyama, Y.Ozeki, K.Itoh, K.Fukui
  • Journal Title: Journal of Biomedical Optics 14(open access)
  • NAID: 120006980200
  • Peer Reviewed
• [Presentation] Label-free observation of tissues by high-speed stimulated Raman spectral microscopy and independent component analysis (2013)
  • Author(s): Ozeki Y., Otsuka Y., Sato S., Hashimoto H., Umemura W., Sumimura K., Nishizawa N., Fukui K., and Itoh K.
  • Organizer: Photonics West 2013
  • Place of Presentation: San Francisco
  • Year and Date: 2013-02-03
• [Presentation] 誘導ラマン散乱を用いた無染色生体顕微鏡 (2012)
  • Author(s): 小関泰之
  • Organizer: 第50回 光波センシング技術研究会
  • Place of Presentation: 東京理科大学
  • Year and Date: 2012-12-05
• [Presentation] High-Speed Molecular Spectral Imaging by Stimulated Raman Scattering Microscopy Using Wavelength-Tunable Pulses (2012)
  • Author(s): Wataru Umemura, Yasuyuki Ozeki, Kenta Fujita, Kazuhiko Sumimura, Norihiko Nishizawa, Kiichi Fukui, Kazuyoshi Itoh
  • Organizer: CLEO 2012
  • Place of Presentation: San Jose
  • Year and Date: 2012-05-09
• [Presentation] 同軸型バランスド検出法と高調波同期法を用いたファイバーレーザーベース誘導ラマン散乱顕微鏡 (2012)
  • Author(s): 能勢啓輔, ら
  • Organizer: 第59回応用物理学関係連合講演会
  • Place of Presentation: 早稲田大学
  • Year and Date: 2012-03-15
• [Presentation] 誘導ラマン散乱顕微鏡による高速分光イメージング (2012)
  • Author(s): 梅村航, ら
  • Organizer: 第59回応用物理学関係連合講演会
  • Place of Presentation: 早稲田大学
  • Year and Date: 2012-03-15
• [Presentation] High-resolution, high-speed tunable grating filter for stimulated Raman spectral imaging (2012)
  • Author(s): Umemura, et al
  • Organizer: BiOS 2012 (Photonic West 2012)
  • Place of Presentation: San Francisco(アメリカ)
  • Year and Date: 2012-02-03
• [Presentation] 誘導ラマン散乱を用いた生体顕微鏡 (2012)
  • Author(s): 小関泰之, ら
  • Organizer: 応用物理学会関西支部セミナー
  • Place of Presentation: 大阪大学(招待講演)
  • Year and Date: 2012-01-30
• [Presentation] FIB/SEMを用いた染色体3次元構造の解明 (2012)
  • Author(s): 福井 希一
  • Organizer: 第63回染色体学会
  • Place of Presentation: 旭川市大雪クリスタルホール
• [Presentation] ヒトコンデンシンSMCヒンジドメインの結晶構造解析 (2012)
  • Author(s): 福井 希一
  • Organizer: 第63回染色体学会
  • Place of Presentation: 旭川市大雪クリスタルホール
• [Presentation] 誘導ラマン散乱を用いる生体顕微鏡システム (2011)
  • Author(s): 小関泰之, ら
  • Organizer: 量子エレクトロニクス研究会
  • Place of Presentation: 上智大学(招待講演)
  • Year and Date: 2011-12-10
• [Presentation] 誘導ラマン散乱による生体イメージングの実証とその高感度化 (2011)
  • Author(s): 小関泰之
  • Organizer: OPJ2011,光学論文賞受賞講演
  • Place of Presentation: 大阪大学(招待講演)
  • Year and Date: 2011-11-30
• [Presentation] 非線形光学顕微鏡による生きた細胞の低侵襲3次元イメージング (2011)
  • Author(s): 伊東一良, ら
  • Organizer: OPJ2011,シンポジウム
  • Place of Presentation: 大阪大学(招待講演)
  • Year and Date: 2011-11-29
• [Presentation] 高速波長可変な回折格子型フィルターを用いた誘導ラマンスペクトラルイメージング (2011)
  • Author(s): 梅村航, ら
  • Organizer: Optics & Photonics Japan 2011
  • Place of Presentation: 大阪大学
  • Year and Date: 2011-11-29
• [Presentation] 誘導ラマン散乱を用いた生体顕微鏡の開発 (2011)
  • Author(s): 小関泰之, ら
  • Organizer: 日本分光学会赤外ラマン分光部会シンポジウム
  • Place of Presentation: 大阪電気通信大学(招待講演)
  • Year and Date: 2011-11-22
• [Presentation] 誘導ラマン散乱を用いた生体顕微法 (2011)
  • Author(s): 小関泰之, ら
  • Organizer: 電子情報通信学会ソサイエティ大会
  • Place of Presentation: 北海道大学(招待講演)
  • Year and Date: 2011-09-15
• [Presentation] 誘導ラマン散乱顕微法のためのピコ秒パルスファイバーレーザーの高調波同期 (2011)
  • Author(s): 能勢啓輔, ら
  • Organizer: 秋季応用物理学会
  • Place of Presentation: 山形大学
  • Year and Date: 2011-08-30
• [Presentation] 高調波同期型誘導ラマン散乱顕微鏡のレーザースキャン化 (2011)
  • Author(s): 梅村航, ら
  • Organizer: 秋季応用物理学会
  • Place of Presentation: 山形大学
  • Year and Date: 2011-08-30
• [Presentation] 誘導ラマン散乱顕微鏡によるバイオイメージング (2011)
  • Author(s): 小関泰之, ら
  • Organizer: 2011年度秋季応用物理学会シンポジウム
  • Place of Presentation: 山形大学(招待講演)
  • Year and Date: 2011-08-29
• [Presentation] 誘導ラマン散乱による生体の顕微イメージング (2011)
  • Author(s): 小関泰之, ら
  • Organizer: 光波シンセシス研究グループ第18回研究会
  • Place of Presentation: 神戸大学(招待講演)
  • Year and Date: 2011-08-04
• [Presentation] Stimulated Raman scattering microscopy system for observing live cells (2011)
  • Author(s): Ozeki, et al
  • Organizer: LPHYS'11, Seminar 5.6.2
  • Place of Presentation: Sarajevo(ボスニア、ヘルッェゴビエ)(招待講演)
  • Year and Date: 2011-07-14
• [Presentation] Subharmonic Synchronization of Picosecond Lasers for Stimulated Raman Scattering Microscopy (2011)
  • Author(s): Umemura, et al
  • Organizer: CLEO : 2011 (Optical Society of America, 2011)
  • Place of Presentation: Maryland(アメリカ)
  • Year and Date: 2011-05-03
• [Presentation] 誘導ラマン散乱による生体イメージングの実証とその高感度化 (2011)
  • Author(s): 小関泰之
  • Organizer: 春季 第58回 応用物理学関係連合講演会
  • Place of Presentation: 神奈川工科大学
  • Year and Date: 2011-03-24
• [Presentation] 誘導ラマン散乱顕微鏡による高速分光イメージング (2011)
  • Author(s): 梅村航,小関泰之,藤田健太,住村和彦,西澤典彦,福井希一,伊東一良
  • Organizer: 第59回応用物理学関係連合講演会
  • Place of Presentation: 早稲田大学
  • Year and Date: 2011-03-15
• [Presentation] 誘導ラマン散乱によるバイオイメージング (2011)
  • Author(s): 小関泰之、伊東一良
  • Organizer: レーザー学会第31回年次大会
  • Place of Presentation: 電気通信大学
  • Year and Date: 2011-01-10
• [Presentation] 誘導パラメトリック発光(SPE)顕微鏡を用いた家族性筋萎縮性側索硬化症(FALS)に関する基礎的研究 (2010)
  • Author(s): 石井万紀子
  • Organizer: 第62回日本生物工学会
  • Place of Presentation: 宮崎県宮崎市
  • Year and Date: 2010-10-28
• [Presentation] High-sensitivity stimulated Raman scattering microscopy (2010)
  • Author(s): Y.Ozeki, K.Itoh
  • Organizer: microCARS2010
  • Place of Presentation: ドイツ(ノルトライン=ヴェストファーレン州バート・ホンネフ)
  • Year and Date: 2010-10-18
• [Presentation] ショット雑音限界感度を有する高調波同期型誘導ラマン散乱顕微鏡 (2010)
  • Author(s): 小関泰之, 北川雄真, 住村和彦, 西澤典彦, 梅村航, 梶山慎一郎, 福井希一, 伊東一良
  • Organizer: 2010年秋季応用物理学会
  • Place of Presentation: 長崎大学
  • Year and Date: 2010-09-16
• [Presentation] 高調波同期した 2 波長光源による誘導ラマン散乱顕微鏡の高感度化 (2010)
  • Author(s): 小関泰之,北川雄真,梅村航,住村和彦,西澤典彦,梶山慎一郎,福井希一,伊東一良
  • Organizer: 第5回超高速光エレクトロニクス研究会
  • Place of Presentation: 慶応大学日吉キャンパス
  • Year and Date: 2010-08-20
• [Presentation] 高調波同期した2波長光源による誘導ラマン散乱顕微鏡の高感度化 (2010)
  • Author(s): 小関泰之, 北川雄真, 梅村航, 住村和彦, 西澤典彦, 梶山慎一郎, 福井希一, 伊東一良
  • Organizer: 第5回超高速光エレクトロニクス研究会
  • Place of Presentation: 慶応大学日吉キャンパス
  • Year and Date: 2010-08-20
• [Presentation] High-sensitivity stimulated Raman scattering (SRS) microscopy based on the subharmonic synchronization technique (2010)
  • Author(s): Y.Ozeki, K.Itoh
  • Organizer: LPHYS'10, Seminar
  • Place of Presentation: ブラジル(パラナ州フォス・ド・イグアス)
  • Year and Date: 2010-07-06
• [Presentation] Subharmonic synchronization of two-color laser pulses for stimulated Raman scattering microscopy (2010)
  • Author(s): Y.Ozeki, Y.Kitagawa, K.Sumimura, N.Nishizawa, W.Umemura, M.Ishii, S.Kajiyama, K.Fukui, K.Itoh
  • Organizer: CLEO2010
  • Place of Presentation: アメリカ(カリフォルニア州サンノゼ)
  • Year and Date: 2010-05-19
• [Presentation] Biological applications of novel nonlinear optical microscopy (2009)
  • Author(s): S.Kajiyama, Y.Ozaki, K.Fukui, K.Itoh
  • Organizer: The 2009 Euro American Workshop on Information Optics
  • Place of Presentation: フランス(パリ)
  • Year and Date: 2009-07-22
• [Presentation] Stimulated Raman scattering microscopy for live-cell imaging with high contrast and high sensitivity (2009)
  • Author(s): Ozeki Y. and Itoh K.
  • Organizer: 18th International Laser Physics Workshop (LPHYS'09)
  • Place of Presentation: Barcelona, Spain
  • Year and Date: 2009-07-16
• [Presentation] Label-free observation of tissues by high-speed stimulated Raman spectral microscopy and independent component analysis
  • Author(s): 伊東 一良
  • Organizer: Photonics West 2013
  • Place of Presentation: San Francisco
  • Invited
• [Presentation] High-speed molecular spectral imaging by stimulated Raman scattering microscopy using wavelength-tunable pulses
  • Author(s): 伊東 一良
  • Organizer: CLEO:2012（Optical Society of America, 2012）
  • Place of Presentation: San Jose
• [Presentation] Sensitivity enhancement of fiber-laser-based stimulated Raman scattering microscopy by intensity noise suppressor
  • Author(s): 伊東 一良
  • Organizer: CLEO:2012（Optical Society of America, 2012）
  • Place of Presentation: San Jose
• [Presentation] 誘導ラマン分光を用いた無染色生体イメージング
  • Author(s): 小関 泰之
  • Organizer: フォトニクス技術フォーラム
  • Place of Presentation: 大阪科学技術センター
  • Invited
• [Presentation] 誘導ラマン散乱を用いた無染色生体顕微鏡
  • Author(s): 小関 泰之
  • Organizer: 第 50 回 光波センシング技術研究会
  • Place of Presentation: 東京理科大学
  • Invited
• [Presentation] 誘導ラマン散乱による生体の分光イメージング
  • Author(s): 伊東 一良
  • Organizer: 第５回超高速フォトニクスシンポジウム
  • Place of Presentation: 日本女子大学
  • Invited
• [Presentation] 波長可変ピコ秒パルス光源を用いた誘導ラマン高速分光イメージング
  • Author(s): 伊東 一良
  • Organizer: 第4回超高速光エレクトロニクス研究会
  • Place of Presentation: 慶応大学
  • Invited
• [Presentation] Independent component analysis of stimulated Raman spectral images
  • Author(s): 伊東 一良
  • Organizer: 応用物理学会
  • Place of Presentation: 愛媛大学
• [Presentation] 誘導ラマン散乱顕微鏡用ファイバー光源におけるパルスの高強度化と雑音特性の検討
  • Author(s): 伊東 一良
  • Organizer: Optics & Photonics Japan 2012
  • Place of Presentation: タワーホール船堀（東京）
• [Presentation] ファイバー光源による誘導ラマン散乱分光顕微鏡
  • Author(s): 伊東 一良
  • Organizer: Optics & Photonics Japan 2012
  • Place of Presentation: タワーホール船堀（東京）
• [Presentation] 誘導ラマン分光顕微鏡と独立成分分析による生体組織観察
  • Author(s): 伊東 一良
  • Organizer: Optics & Photonics Japan 2012
  • Place of Presentation: タワーホール船堀（東京）
• [Presentation] 重水素交換質量分析を用いたヒトSMC タンパク質の相互作用解析
  • Author(s): 福井 希一
  • Organizer: 第12回日本蛋白質科学会年会
  • Place of Presentation: 名古屋国際会議場
• [Presentation] ヒト中期染色体におけるトポIIαおよびコンデンシンの構造的意味
  • Author(s): 福井 希一
  • Organizer: 第35回日本分子生物学会年会
  • Place of Presentation: 福岡国際会議場・マリンメッセ福岡
• [Remarks]
  • URL: http://www.bio.eng.osaka-u.ac.jp/cl/top.php
• [Remarks] 日刊工業新聞、2009年6月8日「SRS 顕微鏡を開発 生きた細胞 3次元観察」
• [Patent(Industrial Property Rights)] 光学顕微鏡、および光学計測 (2010)
  • Inventor(s): 小関 泰之,伊東 一良,嶽 文宏,福井 希一,梶山 慎一郎,北川 雄真,西澤 典彦,住村 和彦
  • Industrial Property Rights Holder: キヤノン株式会社
  • Filing Date: 2010-06-02
  • Overseas