Occurrence of toxic microalgae and toxin contamination mechanisms in marine organisms in Southeast Asia

• Project/Area Number: 21255009
• Research Category: Grant-in-Aid for Scientific Research (A)
• Allocation Type: Single-year Grants
• Section: 海外学術
• Research Field: General fisheries
• Research Institution: The University of Tokyo
• Principal Investigator: FUKUYO Yasuwo 東京大学, アジア生物資源環境研究センター, 教授 (70095511)
• Co-Investigator(Kenkyū-buntansha): OOMURA Takuo 東京大学, アジア生物資源環境研究センター, 特任助教授 (80507880)
• Project Period (FY): 2009 – 2011
• Project Status: Completed (Fiscal Year 2011)
• Budget Amount: ¥48,750,000 (Direct Cost: ¥37,500,000、Indirect Cost: ¥11,250,000); Fiscal Year 2011: ¥11,310,000 (Direct Cost: ¥8,700,000、Indirect Cost: ¥2,610,000); Fiscal Year 2010: ¥16,120,000 (Direct Cost: ¥12,400,000、Indirect Cost: ¥3,720,000); Fiscal Year 2009: ¥21,320,000 (Direct Cost: ¥16,400,000、Indirect Cost: ¥4,920,000)
• Keywords: 有毒微細藻類 / 東南アジア / 貝毒 / 食中毒 / シガテラ / 水産資源利用 / 記憶喪失性貝毒 / 渦鞭毛藻類 / ハプト藻 / ベトナム / フィリピン / 麻痺性貝毒

Research Abstract

Accumulation of toxins responsible for amnesic shellfish poisonings in filter feeding bivalves was widely observed in Southeast Asia countries. Some diatoms were strongly suspected as causative agents, especially those belonging to the genus Pseudo-nitzschia, but recurrence of the toxins in shellfish could not be detected and then confirmation of the causative species was not finalized. Pyrodinium bahamense bloomed in wide areas intermittently, causing poisoning cases in several countries. In addition Alexandrium spp. were also detected as the causative organisms of paralytic shellfish poisoning. Benthic dinoflagellates causing ciguatera fish poisoning were found in wide areas and study on their distribution expansion mechanisms is considered as urgently necessary.

Research Products

• [Journal Article] Dinophysis(Dinophyceae) in Vietnamese waters (2012)
  • Author(s): Le, T. T., Nguyen, V. N. and Fukuyo, Y.
  • Journal Title: Coastal Marine Science Volume: 35 Pages: 73-77
  • Peer Reviewed
• [Journal Article] Two new ASP toxin production types in strains of Nitzschia navis-varingica from the Philippines (2012)
  • Author(s): Romero, M. L. J., Kotaki, Y., Relox, J. Jr., Kundholm, N., Takata, Y., Kodama, M. and Fukuyo Y.
  • Journal Title: Coastal Marine Science Volume: 35巻 Pages: 67-69
  • Peer Reviewed
• [Journal Article] Screening of diatoms that produce ASP toxins in Southernmost Asian waters (2012)
  • Author(s): Thoha, H., Kotaki, Y., Panggabean, L., Lundholm, N., Ogawa, H., Lim, P. T., Takata, Y., Kodama, M. and Fukuyo, Y.
  • Journal Title: Coastal Marine Science Volume: 35巻 Pages: 34-38
  • Peer Reviewed
• [Journal Article] Vulnerability of tropical shellfishes against PSP contamination during bloom of Pyrodinium bahamense var. compressum (2012)
  • Author(s): Montojo, U., Romero, M. L. J., Borja, V. M., Cayme, M. F., Sato, S., Kodama, M. and Fukuyo, Y.
  • Journal Title: Coastal Marine Science Volume: 35巻 Pages: 64-66
  • Peer Reviewed
• [Journal Article] Review of geographical distribution of dinoflagellate cysts in Southeast Asian coasts (2012)
  • Author(s): Furio, E. F., Azanza, R., Fukuyo, Y. and Matsuoka, K.
  • Journal Title: Coastal Marine Science Volume: 35巻 Pages: 20-33
  • Peer Reviewed
• [Journal Article] High individual variation in the toxicity of three species of marine puffer in Vietnam (2012)
  • Author(s): Dao, V. H., Nguyen, T. D., Nguyen, T. H., Takata, Y., Sato, S. Kodama, M. and Fukuyo Y.
  • Journal Title: Coastal Marine Science Volume: 35巻 Pages: 1-6
  • Peer Reviewed
• [Journal Article] Pseudo-nitzschia species, a possible causative organisms of domoic acid in Spondylus versicolor collected from Nha Phu Bay, Khanh Hoa Province, Vietnam (2012)
  • Author(s): Dao, V. H., Omura, T., Takata, Y., Pham, X. K, Fukuyo, Y. and Kodama, M.
  • Journal Title: Coastal Marine Science Volume: 35巻 Pages: 7-10
  • Peer Reviewed
• [Journal Article] 海産微細藻類による各種被害とその研究動向 (2012)
  • Author(s): 大村卓朗・福代康夫
  • Journal Title: 水産振興 Volume: 529号 Pages: 1-65
  • NAID: 40019200208
• [Journal Article] バラスト水による生物移動の生態系や社会活動への影響 (2012)
  • Author(s): 福代康夫・大村卓朗
  • Journal Title: KANRIN Volume: 39巻 Pages: 2-7
  • Peer Reviewed
• [Journal Article] Dinophysis (Dinophyceae) in Vietnamese waters (2012)
  • Author(s): Thanh Tung Le, Van Nguyen Nguyen, Yasuwo Fukuyo
  • Journal Title: Coastal Marine Science Volume: 35(印刷中)
  • Peer Reviewed
• [Journal Article] Screening of diatoms that produce ASP toxins in Southernmost Asian waters (2012)
  • Author(s): Hikmah Thoha, Yuichi Kotaki, Yasuwo Fukuyo, その他6名
  • Journal Title: Coastal Marine Science Volume: 35(印刷中)
  • Peer Reviewed
• [Journal Article] Review of geographical distribution of dinoflagellate cysts in Southeast Asian coasts (2012)
  • Author(s): Elsa Furio, Yasuwo Fukuyo, Kazumi Matsuoka, その他1名
  • Journal Title: Coastal Marine Science Volume: 35(印刷中)
  • Peer Reviewed
• [Journal Article] Pseudo-nitzschia species, a possible causative organisms of domoic acid in Spondylus versicolor collected from Nha Phu Bay, Khanh Hoa Province, Vietnam (2012)
  • Author(s): Dao Viet Ha, Yasuwo Fukuyo, Masaaki Kodama, その他3名
  • Journal Title: Coastal Marine Science Volume: 35(印刷中)
  • Peer Reviewed
• [Journal Article] IMOによる船舶由来の水生生物多様性撹乱に対する対策とその実施困難性-環境対策における科学技術の限界と、実効性を増すための社会的な取り決め- (2011)
  • Author(s): 福代康夫・大村卓朗・長濱幸生
  • Journal Title: 日本海洋政策学会誌 Volume: 1巻 Pages: 78-79
  • Peer Reviewed
• [Journal Article] 大型船舶のバラスト水により越境移動する海洋生物対策とその課題 (2011)
  • Author(s): 大村卓朗・福代康夫
  • Journal Title: 用水と排水 Volume: 53巻 Pages: 796-802
• [Journal Article] Distribution of dinoflagellate cysts in the surface sediment of the coastal areas in Chonburi Province, Thailand (2011)
  • Author(s): Dusit Srivilai, Thaithaworn Lirdwitayaprasit, Yasuwo Fukuyo
  • Journal Title: Coastal Marine Science Volume: 35(印刷中)
  • Peer Reviewed
• [Journal Article] Two new ASP toxin production types in strains of Nitzschia navis-varingca from the Philippines (2011)
  • Author(s): Marc L.Romerom Yuichi Kotaki, Yasuwo Fukuyo, その他4名
  • Journal Title: Coastal Marine Science Volume: 35(印刷中)
  • Peer Reviewed
• [Journal Article] Vulnerability of tropical shellfishes against PSP contamination during bloom of Pyrodinium bahamense var. compressum (2011)
  • Author(s): Ulysses Montojo, Masaaki Kodama, Yasuwo Fukuyo, その他4名
  • Journal Title: Coastal Marine Science Volume: 35(印刷中)
  • Peer Reviewed
• [Journal Article] High individual variation in the toxicity of three species of marine puffer in Vietnam (2011)
  • Author(s): Dao Viet Ha, Masaaki Kodama, Yasuwo Fukuyo, その他4名
  • Journal Title: Coastal Marine Science Volume: 35(印刷中)
  • Peer Reviewed
• [Journal Article] Observations of eleven Pseudo-nitzschia species in Tokyo Bay (2010)
  • Author(s): Yap-Dejeto, L. G., Omura, T., Nagahama Y. and Fukuyo, Y.
  • Journal Title: Japan, La mer Volume: 48巻 Pages: 1-16
  • Peer Reviewed
• [Journal Article] Pseudo-nitzschia species in San Pedro Bay (2010)
  • Author(s): Omura, T., Yap-Dejeto, L. G., Cobacha, M., Cinco, G. and Fukuyo, Y.
  • Journal Title: Leyte Philippines, Proceeding of the 13th International Conference on Harmful Algae Pages: 6-7
  • Peer Reviewed
• [Journal Article] Evaluation of sampling protocols to detect and quantify the diatom Pseudo-nitzschia in San Pedro Bay (2010)
  • Author(s): Yap-Dejeto, L. G., Omura, T., Cinco, G., Cobacha, M. and Fukuyo, Y.
  • Journal Title: Philippines, J. Nature Studies Volume: 8巻 Pages: 123-128
  • Peer Reviewed
• [Journal Article] Observations of eleven Pseudo-nitzschia species in Tokyo Bay, Japan (2010)
  • Author(s): Leni G., Yap-Dejeto, Takuo Omura, Yukio Nagahama, Yasuwo Fukuyo
  • Journal Title: 日仏海洋学会誌 LaMer Volume: 48 Pages: 1-16
  • NAID: 10026602623
  • Peer Reviewed
• [Journal Article] Pseudo-nitzschia species in San Pedro Bay, Leyte Philippines (2010)
  • Author(s): Takuo Omura, Leni G., Yap-Dejeto, Marjorie Cobacha, Genneline Cinco, Yasuwo Fukuyo
  • Journal Title: Proceeding of the 13th International Conference onHarmful Algae Pages: 6-7
  • Peer Reviewed
• [Journal Article] Evaluation of sampling protocols to detect and quantify the diatom Pseudo-nitzschia in San Pedro Bay, Philippines (2010)
  • Author(s): Leni Yap-Dejeto, Takuo Omura, Genneline Cinco, Marjorie Cobacha, Yasuwo Fukuyo
  • Journal Title: Journal of Nature Studies 8 Pages: 123-128
  • Peer Reviewed
• [Journal Article] Domoic acid in small-sized plankton in Nha Phu Bay (2009)
  • Author(s): Dao, V. H., Takata, Y., Omura, T., Nguyen, T. D., Nguyen, T. H., Sato, S., Fukuyo, Y. and Kodama, M.
  • Journal Title: Khanh Hoa Province, Vietnam, La mer Volume: 46巻 Pages: 117-120
  • Peer Reviewed
• [Journal Article] Seasonal variation of domoic acid in a bivalve Spondylus versicolor in association with that in plankton samples in Nha Phu Bay (2009)
  • Author(s): Dao, V. H., Takata, Y., Omura, T., Sato, S., Fukuyo, Y. and Kodama, M.
  • Journal Title: Khanh Hoa, Vietnam, Fish. Sci Volume: 75巻 Pages: 507-512
  • Peer Reviewed
• [Journal Article] Seasonal variation of domoic acid in a bivalve Spondylus versicolor in association with that in plankton samples in Nha Phu Bay, Khanh Hoa, Vietnam (2009)
  • Author(s): Viet Ha Dao, Yoshinobu Takata, Takuo Omura, Shigeru Sato, Yasuwo Fukuyo, Masaaki Kodama
  • Journal Title: Fisheries Science 75 Pages: 507-512
  • NAID: 10024970541
  • Peer Reviewed
• [Journal Article] Domoic acid in small-sized plankton in Nha Phu Bay, Khanh Hoa Province, Vietnam (2009)
  • Author(s): Viet Ha Dao, Yoshinobu Takata, Takuo Omura, Nguyen Tien Dung, Hong Thu Nguyen, Shigeru Sato, Yasuwo Fukuyo, Masaaki Kodama
  • Journal Title: La Mer 46 Pages: 117-120
  • NAID: 10026083888
  • Peer Reviewed
• [Journal Article] Detecting red tides in the eastern Seto Inland Sea with sate llite ocean color imagery (2009)
  • Author(s): Wataru Takahashi, Hiroshi Kawamura, Takuo Omura, Ken Furuya
  • Journal Title: Journal of Oceanography 65 Pages: 647-656
  • Peer Reviewed
• [Journal Article] (2009)
  • Author(s): 福代康夫
  • Journal Title: 海の外来生物 13章 バラスト水による導入の特徴(東海大学出版会) Pages: 195-203
• [Journal Article] (2009)
  • Author(s): 福代康夫・華山伸一・久野勝久
  • Journal Title: 海の外来生物 16章 バラスト水管理条約(東海大学出版会) Pages: 235-244
• [Presentation] Ciguatera causative species in main land of Japan (2011)
  • Author(s): Omura, T. and Fukuyo, Y.
  • Organizer: The 6th Asia-Pacific Phycology Forum2011(APPF2011)
  • Place of Presentation: Yeosu, Korea
  • Year and Date: 2011-10-13
• [Presentation] Ciguatera causative species in main land of Japan. The 6th Asia-Pacific Phycology Forum 2011 (APPF2011) (2011)
  • Author(s): Takuo Omura, Yasuwo Fukuyo
  • Organizer: Asia-Pacific Phycology Forum
  • Place of Presentation: the ocean resort, Yeosu, Korea(招待講演)
  • Year and Date: 2011-10-13
• [Presentation] Harmful algal blooms in Asia during 2001-2010 (2011)
  • Author(s): Fukuyo, Y. and Dao, V. H.
  • Organizer: International Workshop on Investigation and Research of Marine Natural Resources and Environment
  • Place of Presentation: Vietnamese Academy of Science and Technology, Hanoi, Vietnam
  • Year and Date: 2011-09-16
• [Presentation] Harmful Algal Blooms in Asia during 2001-2010 (2011)
  • Author(s): Yasuwo Fukuyo, Dao Viet Ha
  • Organizer: International Workshop on Investigation and Research of Marine Natural Resources and Environment
  • Place of Presentation: Vietnamese Academy of Science and Technology, Hanou, Vietnam(招待講演)
  • Year and Date: 2011-09-16
• [Presentation] Benthic dinoflagellates in Japan (2011)
  • Author(s): Omura T. and Fukuyo, Y. Omura T. and Fukuyo, Y.
  • Organizer: International symposium on subtropical benthic/toxic dinoflagellates
  • Place of Presentation: Gyeongsang National University,韓国
  • Year and Date: 2011-03-31
• [Presentation] Benthic dinoflagellates in Japan (2011)
  • Author(s): Takuo Omura, Yasuwo Fukuyo
  • Organizer: International symposium on subtropical benthic/toxic dinoflagellates
  • Place of Presentation: 韓国、Tongyoung(トンヨン)
  • Year and Date: 2011-03-31
• [Presentation] 本州のGambierdiscusの生理生態,微細藻類の生理活性物質、遺伝子解析、関連生物現象に関するミニシンポジウム (2010)
  • Author(s): 大村卓朗,長濱幸生,福代康夫
  • Organizer: 沖縄健康バイオテクノロジー研究開発センター
  • Place of Presentation: 沖縄
  • Year and Date: 2010-12-13
• [Presentation] 本州のGambierdiscusの生理生態 (2010)
  • Author(s): 大村卓朗, 長濱幸生, 福代康夫
  • Organizer: 微細藻類の生理活性物質、遺伝子解析、関連生物現象に関するミニシンポジウム
  • Place of Presentation: 沖縄健康バイオテクノロジー研究開発センター(沖縄県)
  • Year and Date: 2010-12-13
• [Presentation] 堆積物捕集装置を用いたバラスト水による生物移動量の把握 (2010)
  • Author(s): 大村卓朗,二ノ倉彰一,長濱幸生,福代康夫
  • Organizer: 日本水産学会秋季大会
  • Place of Presentation: 京都
  • Year and Date: 2010-09-24
• [Presentation] 本州におけるシガテラ原因生物のGambierdiscusについて (2010)
  • Author(s): 大村卓朗,長濱幸生,福代康夫
  • Organizer: 日本水産学会秋季大会
  • Place of Presentation: 京都
  • Year and Date: 2010-09-24
• [Presentation] 堆積物捕集装置を用いたバラスト水による生物移動量の把握 (2010)
  • Author(s): 大村卓朗, 二ノ倉彰一, 長濱幸生, 福代康夫
  • Organizer: 日本水産学会秋季大会
  • Place of Presentation: 京都大学(京都府)
  • Year and Date: 2010-09-24
• [Presentation] 本州におけるシガテラ原因生物のGambierdiscusについて (2010)
  • Author(s): 大村卓朗, 長濱幸生, 福代康夫
  • Organizer: 日本水産学会秋季大会
  • Place of Presentation: 京都大学(京都府)
  • Year and Date: 2010-09-24
• [Presentation] New Direction of Ocean Research in the Western Pacific (2010)
  • Author(s): Dao V. H., Omura, T., Takata, Y., Ky, P. X., Nguyen, T. H., Fukuyo, Y. and Kodama, M.
  • Organizer: Pseudo-nitzschia caciantha, a possible causative organism of domoic acid in Spondylus vesicolor from Nha Phu Bay, Vietnam, Horiba International Conference
  • Place of Presentation: 東京大学大気海洋研究所,柏,千葉
• [Presentation] New Direction of Ocean Research in the Western Pacific (2010)
  • Author(s): Matsuoka, K., Lim. P. T., Iwataki, M., Omura T., and Fukuyo, Y.
  • Organizer: Unarmored harmful dinoflagellate Cochlodinium in Southeast Asia, Horiba International Conference
  • Place of Presentation: 東京大学大気海洋研究所,柏,千葉
• [Presentation] New Direction of Ocean Research in the Western Pacific (2010)
  • Author(s): Omura, T., Iwataki, M., Borja, V. M., Thoha, H., Yap-Dejeto, L. G., Nagahama, Y. and Fukuyo, Y.
  • Organizer: Harmful microalgae in Southeast Asia, Horiba International Conference
  • Place of Presentation: 東京大学大気海洋研究所,柏,千葉
• [Presentation] Pseudo-nitzschia caciantha, a possible causative organism of domoic acid accumulated in Spondylus vesicolor in Nha Phu Bay (2010)
  • Author(s): Dao, V. H., Omura, T., Takata, Y., Ky, P. X., Nguyen, T. H., Fukuyo, Y. and Kodama, M.
  • Organizer: Khanh Hoa Province, Vietnam, 14th International Conference on Harmful Algae
  • Place of Presentation: クレタ,ギリシャ
• [Presentation] Pseudo-nitzschia caciantha, apossible causative organism of domoic acid in Spondylus vesicolor from Nha Phu Bay, Vietnam (2010)
  • Author(s): Dao Vet Ha, Takuo Omura, Yoshinobu Takata, Pham Xuan Ky, Nguyen Thu Hong, Yasuwo Fukuyo, Masaaki Kodama
  • Organizer: Horiba International Conference New Direction of Ocean Research in the Western Pacific
  • Place of Presentation: 東京大学大気海洋研究所(千葉県)
• [Presentation] Unarmored harmful dinoflagellate Cochlodinium in Southeast Asia (2010)
  • Author(s): Kazumi Matsuoka, Po Teen Lim, Mitsunori Iwataki, Takuo Omura, Yasuwo Fukuyo
  • Organizer: Horiba International Conference New Direction of Ocean Research in the Western Pacific
  • Place of Presentation: 東京大学大気海洋研究所(千葉県)
• [Presentation] Harmful microalgae in Southeast Asia (2010)
  • Author(s): Takuo Omura, Mitsunori Iwataki, Valeriano M., Borj a, Hikumah Thoha, Leni G., Yap-Dejeto, Yukio Nagahama, Yasuwo Fukuyo
  • Organizer: Horiba International Conference New Direction of Ocean Research in the Western Pacific
  • Place of Presentation: 東京大学大気海洋研究所(千葉県)
• [Presentation] Pseudo-nitzschia caciantha, a possible causative organism of domoic acidaccumulated in Spondylus vesicolor in Nha Phu Bay, Khanh Hoa Province, Vietnam (2010)
  • Author(s): Dao Viet Ha, Takuo Omura, Yoshinobu Takata, Pham Xuan Ky, Nguyen Thu Hong, Yasuwo Fukuyo, Masaaki Kodama
  • Organizer: 14th International Conference on Harmful Algae
  • Place of Presentation: ギリシャ、Crete(クレタ)
• [Presentation] シガテラ原因生物に関する最新の研究 (2009)
  • Author(s): 大村卓朗・長濱幸生・福代康夫
  • Organizer: 平成21年度漁場環境保全関係研究開発推進特別部会赤潮・貝毒部会
  • Place of Presentation: 広島国際会議場,広島
  • Year and Date: 2009-12-10
• [Presentation] シガテラ原因生物に関する最新の研究 (2009)
  • Author(s): 大村卓朗・長濱幸生・福代康夫
  • Organizer: 平成21年度 漁場環境保全関係研究開発推進特別部会 赤潮・貝毒部会
  • Place of Presentation: 広島国際会議場「ダリア」(広島県)
  • Year and Date: 2009-12-10
• [Presentation] ベトナムハイホン沿岸で発生したAlexandrium (2009)
  • Author(s): 大村卓朗,長濱幸生,高田義宜,福代康夫,児玉正昭,佐藤繁, Le, T. T., Nguyen, V. N.
  • Organizer: 日本水産学会秋季大会
  • Place of Presentation: 岩手
  • Year and Date: 2009-10-02
• [Presentation] ベトナム ハイホン沿岸で発生したAlexandrium (2009)
  • Author(s): 大村卓朗, 長濱幸生, 高田義宜, 福代康夫, 児玉正昭, 佐藤繁, Le Thanh Tung, Nguyen Van Nguyen
  • Organizer: 日本水産学会
  • Place of Presentation: いわて県民情報交流センター・ア イーナ(岩手県)
  • Year and Date: 2009-10-02
• [Presentation] フィリピンSan Pedro湾のPseudo-nitzschia spp.-東南アジアにおける有毒有害プランクトンの発生そのVI- (2009)
  • Author(s): 大村卓朗, Yap-Dejeto, L. G., Cobacha, M., Cinco, G.福代康夫
  • Organizer: 日本水産学会春季大会
  • Place of Presentation: 東京海洋大学,東京
  • Year and Date: 2009-03-28
• [Book] Proceedings of the International Workshop on Investigation and Research of Marine Natural Resources and Environment (2011)
  • Author(s): Fukuyo, Y. and Dao, V. H.
  • Total Pages: 430
  • Publisher: Publishing House for Science and Technology, Hanoi
• [Book] ずかんプランクトン (2011)
  • Author(s): 福代康夫・大村卓朗,その他
  • Total Pages: 136
  • Publisher: 技術評論社
• [Book] Coastal Marine Science in Southeast Asia (2011)
  • Author(s): Yasuwo Fukuyo, Masaaki Kodama, Takuo Omura, その他10名
  • Total Pages: 315
  • Publisher: TERAPUB
• [Book] Proceedings of the International Workshop on Investigation and Research of Marine Natural Resources and Environment (2011)
  • Author(s): Yasuwo Fukuyo, Dao Viet Ha
  • Total Pages: 430
  • Publisher: Publishing House for Science and Technology, Hanoi
• [Book] ずかんプランクトン (2011)
  • Author(s): 福代康夫・大村卓朗, その他17名
  • Total Pages: 136
  • Publisher: 技術評論社
• [Book] Coastal Marine Science in Southeast Asia
  • Author(s): Fukuyo, Y. Kodama, M. Omura, T
  • Total Pages: 315
  • Publisher: TERAPUB