In vivo whole-cell recording analysis of response properties of vestibular nucleus neuron to head rotation
| Project/Area Number |
21300147
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Neurophysiology and muscle physiology
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| Research Institution | Gunma University |
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Principal Investigator |
SAITO Yasuhiko 群馬大学, 大学院・医学系研究科, 准教授 (70290913)
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥19,240,000 (Direct Cost: ¥14,800,000、Indirect Cost: ¥4,440,000)
Fiscal Year 2011: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2010: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2009: ¥10,140,000 (Direct Cost: ¥7,800,000、Indirect Cost: ¥2,340,000)
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| Keywords | 前庭神経核 / 眼球運動 / 膜特性 / パッチクランプ / 舌下神経前位核 / ニューロン / シナプス / 前庭動眼反射 / ラット / 求心性入力 |
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| Research Abstract |
We investigated the response properties of neurons in the medial vestibular nucleus (MVN) to head rotations using whole-cell recordings in in vivo preparations of rats. Most MVN neurons tested increased the firing frequency in response to the head rotation to the recording side. Furthermore, the neurons showed an afterhyperpolarization with dual components and a repetitive firing pattern with relatively constant interspike intervals. This finding suggests that MVN neurons that show specific intrinsic properties respond to the head rotation to a specific direction.
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Report
(4 results)
Research Products
(16 results)
