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Development of the bedside type fetus magnetocardiograph and elucidation of the development process of fetus autonomic nerve

Research Project

Project/Area Number 21300158
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Biomedical engineering/Biological material science
Research InstitutionIwate University

Principal Investigator

KOBAYASHI Koichiro  岩手大学, 工学部, 准教授 (60277233)

Co-Investigator(Kenkyū-buntansha) FUKUSHIMA Akimune  岩手医科大学, 医学部, 准教授 (20208937)
OYAMA Daisuke  金沢工業大学, 先端電子技術応用研究所, 助教 (60569888)
Project Period (FY) 2009 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥15,080,000 (Direct Cost: ¥11,600,000、Indirect Cost: ¥3,480,000)
Fiscal Year 2012: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Fiscal Year 2011: ¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2010: ¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2009: ¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Keywords生体生命情報学 / 医用診断機器開発 / 計測工学 / 胎児自律神経 / 心磁図計測 / 医療診断機器開発
Research Abstract

Fetus magnetocardiograph which did not require the magnetically shielded room was developed. The fetus magnetocardiograph is using the low noise and wide range type analog control circuit. The fetus magnetocardiogram is weak signal, and it is measured in the condition that was buried in the noise. Then, noise rejection program using the independent component analysis and the Wiener filter was made. The extraction of the fetal heart rate fluctuation became possible. And, features of heart rate variability of the fetus which changed with the pregnancy progress were confirmed.

Report

(5 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • 2009 Annual Research Report
  • Research Products

    (42 results)

All 2013 2012 2011 2010 2009 Other

All Journal Article (17 results) (of which Peer Reviewed: 17 results) Presentation (21 results) Book (3 results) Remarks (1 results)

  • [Journal Article] Rejection of Wire-induced Magnetic Noise Using Wavelet Transformation and Independent Component Analysis for Magnetocardiogram2013

    • Author(s)
      Koichiro Kobayashi
    • Journal Title

      Journal of the Magnetics Society of Japan

      Volume: 37

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Active Magnetic Shielding using Symmetric Magnetic Field Sensor Method2012

    • Author(s)
      K. Kobayashi, A. Kon, M. Yoshizawa, Y. Uchikawa
    • Journal Title

      IEEE Trans. Magnetics

      Volume: Vol.48, No.11 Issue: 11 Pages: 4554-4557

    • DOI

      10.1109/tmag.2012.2197854

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Prenatal Diagnosis of Fetal Arrhythmias and Assessment of Autonomic Nervous System Activity by Fetal Magneto- cardiography2012

    • Author(s)
      A. Fukushima, A. Matsumoto, M. Terata, T. Kanasugi, K. Nakai
    • Journal Title

      The Open Medical Devices Journal

      Volume: Vol.4 Issue: 1 Pages: 13-21

    • DOI

      10.2174/1875181401204010013

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Real-time Head Localization System for Magnetoencephalography2012

    • Author(s)
      小山大介、小林宏一郎
    • Journal Title

      Journal of the Magnetics Society of Japan

      Volume: 36 Issue: 6 Pages: 345-351

    • DOI

      10.3379/msjmag.1209R003

    • NAID

      130002112222

    • ISSN
      1882-2924, 1882-2932
    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The electronic circuit model for the SEF responses2012

    • Author(s)
      小林宏一郎
    • Journal Title

      Journal of the Magnetics Society of Japan

      Volume: 36 Issue: 5 Pages: 318-322

    • DOI

      10.3379/msjmag.1209R002

    • NAID

      130002112221

    • ISSN
      1882-2924, 1882-2932
    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Study of Spread of Estimated Solution Using Spatial Filter Method for Magnetocardiograms2012

    • Author(s)
      小林宏一郎
    • Journal Title

      Journal of the Magnetics Society of Japan

      Volume: 36 Issue: 3 Pages: 272-276

    • DOI

      10.3379/msjmag.1203R007

    • NAID

      130002112346

    • ISSN
      1882-2924, 1882-2932
    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Association of blue rubber bleb nevus syndrome and placenta previa: Report of a case2012

    • Author(s)
      Akinune Fukushima
    • Journal Title

      Journal of Clinical Ultrasound

      Volume: 11 Issue: 8 Pages: 517-520

    • DOI

      10.1002/jcu.22000

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Wide dynamic range analog FLL system using high-Tc SQUID for biomagnetic measurements2011

    • Author(s)
      K. Kobayashi, M. Yoshizawa, Y. Uchikawa
    • Journal Title

      IEEE Trans. Magnetics

      Volume: Vol.47, No.10 Issue: 10 Pages: 2871-2873

    • DOI

      10.1109/tmag.2011.2158199

    • Related Report
      2012 Final Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Electric Current Imaging by Ultrasono- graphy and SQUID Magnetometry2011

    • Author(s)
      D. Oyama, M. Higuchi, Y. Adachi, J. Kawai, G. Uehara, H. Kado, K. Kobayashi
    • Journal Title

      IEEE Transactions on Applied Superconductivity

      Volume: Vol.21, No.3 Issue: 3 Pages: 440-443

    • DOI

      10.1109/tasc.2010.2084984

    • Related Report
      2012 Final Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Noise Rejection Using Independent Component Analysis and Wiener Filter For Fetal Magnetocardiogram2011

    • Author(s)
      佐藤嘉輝,小林宏一郎,中居賢司,福島明宗,吉澤正人,内川義則
    • Journal Title

      Journal of the Magnetics Society of Japan

      Volume: 35 Issue: 3 Pages: 308-311

    • DOI

      10.3379/msjmag.1104R016

    • NAID

      130000677019

    • ISSN
      1882-2924, 1882-2932
    • Related Report
      2012 Final Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Design Method for Realization of Open-Type Magnetically Shielded Room Composed of Magnetic Square Cylinders for MRI2011

    • Author(s)
      Koichiro Kobayashi
    • Journal Title

      IEEE Trans.Magnetics

      Volume: 47 Issue: 5 Pages: 945-957

    • DOI

      10.1109/tmag.2010.2072494

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Discrimination of Multiple Sources of 3D Biomagnetic Field using Frequency and Phase Analyses2011

    • Author(s)
      小林宏一郎
    • Journal Title

      Journal of the Magnetics Society of Japan

      Volume: 35 Issue: 3 Pages: 312-318

    • DOI

      10.3379/msjmag.1104R017

    • NAID

      130000677020

    • ISSN
      1882-2924, 1882-2932
    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Environmental Magnetic Noise Rejection Using Independent Component Analysis for MCG -Automated Component Selection and Number of Contraction Dimension Decisions-2010

    • Author(s)
      小林宏一郎,小山田健太,吉澤正人,内川義則
    • Journal Title

      Journal of the Magnetics Society of Japan

      Volume: 34 Issue: 2 Pages: 156-160

    • DOI

      10.3379/msjmag.1002R0010

    • NAID

      130000168432

    • ISSN
      1882-2924, 1882-2932
    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] 高帯域フィードバック回路を用いたSQUID磁束計における高周波ノイズ影響の緩和2010

    • Author(s)
      小山大介
    • Journal Title

      Journal of the Magnetics Society of Japan

      Volume: 34 Pages: 444-448

    • NAID

      130000262899

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 電子回路モデルを用いた体性感覚誘発脳磁界応答の一考察2010

    • Author(s)
      渡辺理, 小林宏一郎
    • Journal Title

      Journal of the Magnetics Society of Japan

      Volume: 34 Pages: 431-435

    • NAID

      130000262896

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 心磁図における独立成分分析を用いた環境磁気ノイズ除去-成分選択と縮約次元数決定の自動化-2010

    • Author(s)
      小林宏一郎
    • Journal Title

      日本磁気学会誌 34

      Pages: 156-160

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 心磁図のICAを用いた環境磁気ノイズ除去におけるパラメータ決定の検討2010

    • Author(s)
      小林宏一郎, 他3名
    • Journal Title

      日本磁気学会誌 34

      Pages: 146-150

    • NAID

      130000168431

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Presentation] Development of wide dynamic range analog flux-locked loop using flux-quanta counting for SQUID magnetometer2012

    • Author(s)
      K. Kobayashi, D. Oyama, 他
    • Organizer
      Applied Superconductivity Conference
    • Place of Presentation
      Oregon Convention Center in Portland (USA)
    • Year and Date
      2012-10-08
    • Related Report
      2012 Final Research Report
  • [Presentation] 64 チャネル心磁計と187ch ベクトル合成心電計の開発ー臨床での意義と課題2012

    • Author(s)
      中居賢司,小林宏一郎, 他
    • Organizer
      日本生体磁気学会
    • Place of Presentation
      東京電機大学(東京都)
    • Year and Date
      2012-05-31
    • Related Report
      2012 Final Research Report
  • [Presentation] SQUID磁束計用アナログ型FQCを用いたFLLの高ダイナミックレンジ化2012

    • Author(s)
      小林 宏一郎、小山大介
    • Organizer
      日本生体磁気学会
    • Place of Presentation
      東京電機大学(東京都)
    • Related Report
      2012 Annual Research Report
  • [Presentation] 64 チャネル心磁計と187ch ベクトル合成心電計の開発-臨床での意義と課題-2012

    • Author(s)
      小林 宏一郎
    • Organizer
      日本生体磁気学会
    • Place of Presentation
      東京電機大学(東京都)
    • Related Report
      2012 Annual Research Report
  • [Presentation] 二等辺三角形コイルを用いたMEG ファントムの開発と不確かさの評価2012

    • Author(s)
      小山大介
    • Organizer
      日本生体磁気学会
    • Place of Presentation
      東京電機大学(東京都)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Development of wide dynamic range SQUID magnetometer using analog FLL with flux-quanta counting2012

    • Author(s)
      Koichiro Kobayashi, Daisuke Oyama
    • Organizer
      International Conference on Biomagnetism
    • Place of Presentation
      France at Maison de la Chimie (France)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Rejection of Wire-induced Magnetic Noise Using Wavelet Transformation and Independent Component Analysis for Magnetocardiogram2012

    • Author(s)
      Koichiro Kobayashi
    • Organizer
      International Conference of the Asian Union of Magnetics Societies (ICAUMS2012)
    • Place of Presentation
      奈良県新公会堂(奈良県)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Measurement of Magnetic Interference Induced by Measurement and Gradient Field Coils for Low-Field MRI Systems2012

    • Author(s)
      Daisuke Oyama
    • Organizer
      International Conference of the Asian Union of Magnetics Societies (ICAUMS2012)
    • Place of Presentation
      奈良県新公会堂(奈良県)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Development of wide dynamic range analog flux-locked loop using flux-quanta counting for SQUID magnetometer2012

    • Author(s)
      Koichiro Kobayashi, Daisuke Oyama
    • Organizer
      Applied Superconductivity Centennial Conference
    • Place of Presentation
      Oregon Convention Center (USA)
    • Related Report
      2012 Annual Research Report
  • [Presentation] 生体磁気計測用マーカコイルのリアルタイム位置観測装置の開発2011

    • Author(s)
      小山大介
    • Organizer
      日本磁気学会
    • Place of Presentation
      新潟コンベンションセンター(新潟県)
    • Year and Date
      2011-09-27
    • Related Report
      2011 Annual Research Report
  • [Presentation] The parallel arithmetic method of digital FLL circuit for SQUID magnetometer using CPLD2011

    • Author(s)
      K. Kobayashi, D. Oyama, 他
    • Organizer
      Superconductivity Centennial Conference
    • Place of Presentation
      World Forum Convention Centre (Netherlands)
    • Year and Date
      2011-09-20
    • Related Report
      2012 Final Research Report
  • [Presentation] Real-time coil position monitoring system for biomagnetic measurements2011

    • Author(s)
      Daisuke Oyama
    • Organizer
      Superconductivity Centennial Conference (SCC2011)
    • Place of Presentation
      World Forum Den Haag(Netherlands)
    • Year and Date
      2011-09-20
    • Related Report
      2011 Annual Research Report
  • [Presentation] The parallel arithmetic method of digital FLL circuit for SQUID magnetometer using CPLD2011

    • Author(s)
      Koichiro Kobayashi
    • Organizer
      Superconductivity Centennial Conference(SCC2011)
    • Place of Presentation
      World Forum Den Haag(Netherlands)
    • Year and Date
      2011-09-20
    • Related Report
      2011 Annual Research Report
  • [Presentation] CPLDを用いたSQUID磁束計用デジタルFLL回路の並列演算方式の検討2011

    • Author(s)
      小林宏一郎
    • Organizer
      日本生体磁気学会
    • Place of Presentation
      九州大学(福岡県)
    • Year and Date
      2011-06-03
    • Related Report
      2011 Annual Research Report
  • [Presentation] 空間フィルタ法を用いた心磁図の信号源推定に関する研究2011

    • Author(s)
      小林宏一郎
    • Organizer
      日本生体磁気学会
    • Place of Presentation
      九州大学(福岡県)
    • Year and Date
      2011-06-02
    • Related Report
      2011 Annual Research Report
  • [Presentation] 64チャンネ心磁図による胎児不整脈の診断とその治療2010

    • Author(s)
      福島明宗,小林宏一郎, 他
    • Organizer
      日本生体磁気学会
    • Place of Presentation
      東京大学(千葉県)
    • Year and Date
      2010-07-29
    • Related Report
      2012 Final Research Report
  • [Presentation] Parameters decision of noise rejection using independent component analysis for low SNR magnetocardiogram2010

    • Author(s)
      小林宏一郎
    • Organizer
      日本生体医工学会
    • Place of Presentation
      日本、大阪国際交流センター
    • Year and Date
      2010-06-26
    • Related Report
      2010 Annual Research Report
  • [Presentation] Parameter decision of independent component analysis for low SNR magnetocardiogram signal2010

    • Author(s)
      K.Kobayashi
    • Organizer
      International Conference on Biomagnetism
    • Place of Presentation
      クロアチア、ドブロニク
    • Year and Date
      2010-04-01
    • Related Report
      2010 Annual Research Report
  • [Presentation] The noise rejection method for magnetocardiogram using wavelet transformation and independent component analysis2010

    • Author(s)
      小林宏一郎
    • Organizer
      INTERMAG2010
    • Place of Presentation
      USA、Washington
    • Year and Date
      2010-01-22
    • Related Report
      2009 Annual Research Report
  • [Presentation] 開胸手術後の心磁図におけるウェーブレット変換と独立成分分析を用いたノイズ除去-第2報-2009

    • Author(s)
      小林宏一郎
    • Organizer
      日本生体磁気学会大会
    • Place of Presentation
      石川県、金沢市文化ホール
    • Year and Date
      2009-05-28
    • Related Report
      2009 Annual Research Report
  • [Presentation] モバイル型心磁計のための高温超伝導SQUIDシステムの開発2009

    • Author(s)
      小林宏一郎
    • Organizer
      日本生体医工学会
    • Place of Presentation
      東京都、船堀タワーホール
    • Year and Date
      2009-04-23
    • Related Report
      2009 Annual Research Report
  • [Book] InTech SUPERCONDUCTORS -PROPERTIES, TECHNOLOGY, AND APPLICATIONS2012

    • Author(s)
      K. Kobayashi, 他
    • Related Report
      2012 Final Research Report
  • [Book] Superconductors - Properties, Technology, and Applications2012

    • Author(s)
      Kobayashi Koichiro
    • Total Pages
      436
    • Publisher
      InTech - Open Access Company
    • Related Report
      2012 Annual Research Report
  • [Book] Superconductors-Properties, Technology, and Applications2012

    • Author(s)
      Kobayashi Koichiro : 分担著者
    • Total Pages
      16
    • Publisher
      InTech-Open Access Company
    • Related Report
      2011 Annual Research Report
  • [Remarks]

    • URL

      http://www.wel.iwate-u.ac.jp/kobayashi/

    • Related Report
      2012 Final Research Report

URL: 

Published: 2009-04-01   Modified: 2019-07-29  

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