Dynamic functional analysis and construction of solid image of peripheral vessels by optical coherence tomography
| Project/Area Number |
21300163
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Biomedical engineering/Biological material science
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| Research Institution | Osaka University |
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Principal Investigator |
OHMI Masato 大阪大学, 大学院・医学系研究科, 教授 (60273645)
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| Co-Investigator(Kenkyū-buntansha) |
HARUNA Masamitsu 大阪大学, 産学連携本部, 特任教授 (20029333)
NAKATANI Satoshi 大阪大学, 大学院・医学系研究科, 教授 (80393221)
HIRATA Masayuki 大阪大学, 大学院・医学系研究科, 特任准教授 (30372626)
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥18,330,000 (Direct Cost: ¥14,100,000、Indirect Cost: ¥4,230,000)
Fiscal Year 2011: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2010: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2009: ¥11,960,000 (Direct Cost: ¥9,200,000、Indirect Cost: ¥2,760,000)
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| Keywords | 生体情報 / 計測 / ダイナミックOCT / SS-OCT / 末梢血管系 / AVA / ダイナミック機能解析 |
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| Research Abstract |
In this study, it is demonstrated that dynamic observation and analysis of peripheral vessels underneath skin surface by sweat-source optical coherence tomography. In the experiment, we developed OCT system which has the high image resolution of 5μm with the high image acquisition rate of 50 frames/ s. In vivo observation for dynamic functional analysis not only small arteries and veins of human fingers but also arteriole and venule were demonstrated. In particular, we developed the solid image of the arteriole and the venule by the 3-dimensional OCT images. Furthermore, simultaneous measurement of dynamics of the physiological function of peripheral vessels for the activity of the autonomic nervous system were demonstrated.
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Report
(4 results)
Research Products
(71 results)
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[Journal Article] 200 kHz swept light sourceequipped with KTN deflector foroptical coherence tomography2012
Author(s)
Y. Okabe, Y. Sasaki, M. Ueno, T. Sakamoto, S. Toyoda, S. Yagi, K. Naganuma, K. Fujiura, Y. Sakai, J. Kobayashi, K. Omiya, M. Ohmi, M. Haruna
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Journal Title
Electron. Lett
Volume: Vol.48, Issue4
Issue: 4
Pages: 201-202
DOI
Related Report
Peer Reviewed
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[Journal Article] Improvement of coherence length in a200-kHz swept light source equippedwith a KTN deflector2012
Author(s)
S. Yagi, K. Naganuma, T. Imai, Y. Shibata, J. Miyazu, M. Ueno, Y. Okabe, Y. Sasaki, K. Fujiura, M. Sasaura, K. Kato, M. Ohmi, M. Haruna
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Journal Title
SPIE PhotonicsWest BiOS 2012
Pages: 8213-110
URL
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[Journal Article]2009
Author(s)
佐藤俊一, 他
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Journal Title
バイオメディカルフォトニクス-生体医用光学の基礎と応用-(電気学会)
Pages: 126-139
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