Effect of training on paralyzed muscles of persons with spinal cord injury

• Project/Area Number: 21300229
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Sports science
• Research Institution: Hiroshima University
• Principal Investigator: YAMASAKI Masahiro 広島大学, 大学院・総合科学研究科, 教授 (40128327)
• Co-Investigator(Kenkyū-buntansha): FUNASE Kozo 広島大学, 大学院・総合科学研究科, 教授 (40173512) ; WADA Masanobu 広島大学, 大学院・総合科学研究科, 教授 (80220961) ; ISHII Yoshimasa 広島大学, 大学院・教育学研究科, 准教授 (00397978)
• Co-Investigator(Renkei-kenkyūsha): HASEGAWA Hiroshi 広島大学, 大学院・総合科学研究科, 准教授 (70314713)
• Project Period (FY): 2009 – 2011
• Project Status: Completed (Fiscal Year 2011)
• Budget Amount: ¥8,450,000 (Direct Cost: ¥6,500,000、Indirect Cost: ¥1,950,000); Fiscal Year 2011: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000); Fiscal Year 2010: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000); Fiscal Year 2009: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
• Keywords: 脊髄損傷 / 筋委縮 / トレーニング / 筋電図 / MRI測定 / 筋小胞体 / 筋萎縮

Research Abstract

In four of 11 subjects, only M waves were observed on soleus, gastrocnemisu and tibialis anterior. The rest of the subjects showed no responses of EMGs on any muscles. The four subjects complained of spasticity of legs in their daily life. The spasticity was considered as training effects on paralyzed muscles. Although electric stimulations were conducted on the paralyzed muscles for six months in order to train the muscles, no response of EMG was found. In the rat experiment, the biochemical changes of muscles were found in the early stage of spinal cord section.

Research Products

• [Journal Article] The effects of eccentric contraction on myofibrillar proteinsin rat skeletal muscle (2010)
  • Author(s): Kanzaki, K., Kuratni, M., Mishima, T., Matsunaga, S., Yanaka, N., Usui, S., Wada, M.:
  • Volume: 110
  • Pages: 943-952
  • Peer Reviewed
• [Presentation] 完全脊髄損傷後のスポーツ愛好者における麻痺筋に対する誘発筋電図の検討 (2011)
  • Author(s): 石井良昌
  • Organizer: 第22回日本リハビリテーション医学会中国・四国地方会
  • Place of Presentation: 岡山市
  • Year and Date: 2011-12-14
• [Presentation] 完全脊髄損傷後のスポーツ愛好者における麻庫筋に対する誘発筋電図の検討 (2011)
  • Author(s): 右井良昌, 他
  • Organizer: 第22回日本リハビリテーション医学会中国・四国地方会
  • Place of Presentation: 岡山
  • Year and Date: 2011-12-04
• [Presentation] The effect ofeccentric contractions on sarco-plasmic reticulum Ca^<2>-sequestering capacity and proteolytic activity infast-twitch muscle of the rat (2011)
  • Author(s): Kanzaki, K., Kuratani, M., Matsunaga, S, Yamada, T., Wada, M.
  • Organizer: 40^th Euro pean Muscle Conference
  • Place of Presentation: Berlin-Buch, Germany
  • Year and Date: 2011-09-16
• [Presentation] Evaluation of the lower-legmuscle characteristics in athleteswith complete spinal cord injury (2011)
  • Author(s): Ishii, Y., Yamasaki, M., Funase, K., Uedak T.
  • Organizer: 16^th Euro pean College of Sports Sciences
  • Place of Presentation: Liverpool, England
  • Year and Date: 2011-07-08
• [Presentation] MRI and Surface EMG study on paralyzedmuscle in persons with spinal cordinjury (2011)
  • Author(s): Yamasaki, M., Funase, K., Ishii, Y
  • Organizer: 18^th International Symposiumon Adapted Physical Activity
  • Place of Presentation: Paris, France
  • Year and Date: 2011-07-07
• [Presentation] MRI and Surface EMG study on paralyzed muscle in persons with spinal cord injury (2011)
  • Author(s): Mashiro Yamasaki, et al
  • Organizer: 18^<th> International Symposium on Adapted Physical Activity
  • Place of Presentation: Paris, France
  • Year and Date: 2011-07-07
• [Presentation] Evaluation of the lower-leg muscle characteristics in athletes with complete spinal cord injury (2011)
  • Author(s): Yoshimasa Ishii, et al
  • Organizer: 16^<th> European College of Sports Sciences
  • Place of Presentation: Liverpool, England
  • Year and Date: 2011-07-06
• [Presentation] 脊髄損傷者の麻痺部下肢残存筋量と筋活動の関係について (2010)
  • Author(s): 山崎昌廣, 船瀬広三, 石井良昌
  • Organizer: 第14回日本アダプテッド体育・スポーツ学会
  • Place of Presentation: 富山市
  • Year and Date: 2010-12-05
• [Presentation] スポーツ活動を伴う完全脊髄損傷患者の下肢筋に関する検討 (2010)
  • Author(s): 石井良昌, 田中徹, 陳周業
  • Organizer: 第21回日本臨床スポーツ医学会学術集会
  • Place of Presentation: つくば
  • Year and Date: 2010-11-07
• [Presentation] スポーツ活動を行う完全脊髄損傷者の下肢筋に関する検討 (2010)
  • Author(s): 石井良昌
  • Organizer: 第21回臨床スポーツ医学会学術集会
  • Place of Presentation: つくば市
  • Year and Date: 2010-11-06
• [Presentation] The effect of eccentric contractions on sarcoplasmic reticu-lum Ca^<2> handling in fast-twitchskeletal muscle of the rat (2010)
  • Author(s): Kanzaki, K, Kuratani, M., Matsunaga, S., Wada M.
  • Organizer: 39^th Euro pean Muscle Conference
  • Place of Presentation: Padova, Italy
  • Year and Date: 2010-09-13