Budget Amount *help |
¥17,680,000 (Direct Cost: ¥13,600,000、Indirect Cost: ¥4,080,000)
Fiscal Year 2011: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2010: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2009: ¥7,540,000 (Direct Cost: ¥5,800,000、Indirect Cost: ¥1,740,000)
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Research Abstract |
The object of the present study was to identify new plasma or serum biomarkers for gerontology based on epidemiological analysis. We found that eHSP70 was related with sarcopenia and very mild dementia and that beta2-microglobulin was related with frailty. Our findings could be applied to the development of a screening tool to distinguish these aging disorders. In addition, we found a mechanism of HSP70 release using high intensity aerobic exercise, which results imply that ATP in plasma is a trigger of HSP70 release.
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