• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Preparation of molecularly imprinted gel beads that selectively adsorb endotoxin

Research Project

Project/Area Number 21310062
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Environmental technology/Environmental materials
Research InstitutionTokyo University of Technology

Principal Investigator

MINOURA Norihiko  東京工科大学, 応用生物学部, 教授 (10358111)

Co-Investigator(Kenkyū-buntansha) AIBA Seiichi  産業技術総合研究所, 生物プロセス研究部門, 主任研究員 (50344156)
Project Period (FY) 2009 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥18,460,000 (Direct Cost: ¥14,200,000、Indirect Cost: ¥4,260,000)
Fiscal Year 2011: ¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2010: ¥6,240,000 (Direct Cost: ¥4,800,000、Indirect Cost: ¥1,440,000)
Fiscal Year 2009: ¥6,890,000 (Direct Cost: ¥5,300,000、Indirect Cost: ¥1,590,000)
Keywords高分子合成 / 分子認識 / 表面・界面物性 / 有害化学物質 / エンドトキシン / 分子インプリント法 / アミノ酸 / トリペプチド / 表面プラズモン共鳴法 / アクリルアミド誘導体
Research Abstract

To remove endotoxin from water, we plan to develop polymer hydrogels that selectively adsorb endotoxin. We successfully prepared polymer hydrogels with endotoxin-binding sites by applying a molecular imprinting technique and using amino acid derivatives or tripeptide derivatives as functional monomers. The hydrogels obtained selectively adsorbed endotoxin even in a coexistence of the other substances, and after adsorption of endotoxin to the hydrogels was completed the hydrogels could be regenerated by washing with acidic and basic solutions.

Report

(4 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • 2009 Annual Research Report
  • Research Products

    (12 results)

All 2012 2011 2010

All Journal Article (1 results) (of which Peer Reviewed: 1 results) Presentation (11 results)

  • [Journal Article] Development of lipid A-imprinted polymer hydrogels that selectively recognize lipopolysaccharides2012

    • Author(s)
      Keiichi Ogawa, Masumi Hyuga, Tomoko Okada, Norihiko Minoura
    • Journal Title

      Biosensors and Bioelectronics

      Volume: (in press)

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Presentation] 大腸菌LPSを選択的に認識するlipid A-インプリントヒドロゲルの調製2011

    • Author(s)
      小川桂一、日向麻須美、岡田朋子、箕浦憲彦
    • Organizer
      日本膜学会・膜シンポジウム2011
    • Place of Presentation
      健康文化村カルチャーリゾートフェストーネ(沖縄県)
    • Year and Date
      2011-11-19
    • Related Report
      2011 Final Research Report
  • [Presentation] 大腸菌LPSを選択的に認識するlipid A-インプリントヒドロゲルの調製2011

    • Author(s)
      小川桂一、日向麻須美、岡田朋子、箕浦憲彦
    • Organizer
      日本膜学会、膜シンポジウム2011
    • Place of Presentation
      健康文化村カルチャーリゾート フェストーネ(沖縄県)
    • Year and Date
      2011-11-19
    • Related Report
      2011 Annual Research Report
  • [Presentation] エンドトキシン捕捉能を有する分子インプリントゲルビーズの調製2011

    • Author(s)
      小木曽真佐代、相羽誠一、箕浦憲彦
    • Organizer
      日本化学会・第5回バイオ関連化学シンポジウム
    • Place of Presentation
      つくば国際会議場「エポカルつくば」(茨城県)
    • Year and Date
      2011-09-12
    • Related Report
      2011 Final Research Report
  • [Presentation] エンドトキシン捕捉能を有する分子インプリントゲルビーズの調製2011

    • Author(s)
      小木曽真佐代、相羽誠一、箕浦憲彦
    • Organizer
      日本化学会、第5回バイオ関連化学シンポジウム
    • Place of Presentation
      つくば国際会議場「エポカルつくば」(茨城県)
    • Year and Date
      2011-09-12
    • Related Report
      2011 Annual Research Report
  • [Presentation] リポ多糖認識能をもつポリペプチドの創製と親和性評価2011

    • Author(s)
      井上浩輝、日向麻須美、岡田朋子、箕浦憲彦
    • Organizer
      日本化学会第91春季年会
    • Place of Presentation
      神奈川大学(神奈川県)
    • Year and Date
      2011-03-26
    • Related Report
      2011 Final Research Report 2010 Annual Research Report
  • [Presentation] Development of lipopolysaccharide(LPS)-imprinted gel2010

    • Author(s)
      Keiichi Ogawa, Masumi Hyuga, Tomoko Okada, Norihiko Minoura
    • Organizer
      2010環太平洋国際化学会議
    • Place of Presentation
      Hawaii(USA)
    • Year and Date
      2010-12-17
    • Related Report
      2011 Final Research Report
  • [Presentation] Development of lipopolysaccharide(LPS)-imprinted gel2010

    • Author(s)
      Keiichi Ogawa, Masumi Hyuga, Tomoko Okada, Norihiko Minoura
    • Organizer
      2010環太平洋国際化学会議(Pacifichem 2010)
    • Place of Presentation
      Hawaii(USA)
    • Year and Date
      2010-12-17
    • Related Report
      2010 Annual Research Report
  • [Presentation] リポ多糖認識能をもつペプチドの創製と親和性評価2010

    • Author(s)
      井上浩輝、日向麻須美、岡田朋子、箕浦憲彦
    • Organizer
      日本化学会第90春季年会
    • Place of Presentation
      近畿大学(大阪府)
    • Year and Date
      2010-03-28
    • Related Report
      2011 Final Research Report
  • [Presentation] リポ多糖認識能をもつペプチドの創製と親和性評価2010

    • Author(s)
      井上浩輝, 他3名
    • Organizer
      日本化学会弟90春季年会
    • Place of Presentation
      近畿大学(大阪府)
    • Year and Date
      2010-03-28
    • Related Report
      2009 Annual Research Report
  • [Presentation] Lipopolysaccharide(LPS)に対する特異的認識能をもつインプリントゲルの作製2010

    • Author(s)
      小川桂一、日向麻須美、岡田朋子、箕浦憲彦
    • Organizer
      日本化学会第90春季年会
    • Place of Presentation
      近畿大学(大阪府)
    • Year and Date
      2010-03-27
    • Related Report
      2011 Final Research Report
  • [Presentation] Lipopolysaccharide(LPS)に対する特異的認識能をもつインプリントゲルの作製2010

    • Author(s)
      小川桂一, 他3名
    • Organizer
      日本化学会弟90春季年会
    • Place of Presentation
      近畿大学(大阪府)
    • Year and Date
      2010-03-27
    • Related Report
      2009 Annual Research Report

URL: 

Published: 2009-04-01   Modified: 2016-04-21  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi