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Establishment of a novel electron tomographic reconstruction method based on a newly found property of image fine dots which convergently move to definitive positions

Research Project

Project/Area Number 21310075
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Nanomaterials/Nanobioscience
Research InstitutionKogakuin University

Principal Investigator

BABA Norio  工学院大学, 情報学部, 教授 (80164896)

Co-Investigator(Renkei-kenkyūsha) KANEKO Kenji  九州大学, 大学院・工学研究院, 教授 (30336002)
BABA Misuzu  工学院大学, 総合研究所, 研究員 (80435528)
Project Period (FY) 2009 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥18,590,000 (Direct Cost: ¥14,300,000、Indirect Cost: ¥4,290,000)
Fiscal Year 2011: ¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2010: ¥8,710,000 (Direct Cost: ¥6,700,000、Indirect Cost: ¥2,010,000)
Fiscal Year 2009: ¥6,110,000 (Direct Cost: ¥4,700,000、Indirect Cost: ¥1,410,000)
Keywords電子線CT / 画像再構成 / 画像復元 / 逆問題 / ナノ材料 / ナノバイオ
Research Abstract

With an electron microscope nano-tomographic images(nano-order resolution) of various materials can be taken, in which the same principle as medical X-ray CT apparatuses is used. However, in general, because a specimen is put on a support thin film extended horizontally the tilt angle is limited to about 60deg.(90deg. ideal). Therefore, only distorted tomographic images are obtained. In this research work, a novel image reconstruction method was devised. This was applied to them and as a result successful images unaffected by the distortion artifact were obtained. Furthermore, it was achieved that the electron dose was reduced to about 20% as compared with the general case.

Report

(4 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • 2009 Annual Research Report
  • Research Products

    (19 results)

All 2012 2011 2010 2009

All Journal Article (5 results) (of which Peer Reviewed: 3 results) Presentation (12 results) Patent(Industrial Property Rights) (2 results)

  • [Journal Article] 電子線トモグラフィー法その2 :課題と応用例2010

    • Author(s)
      金子賢治、馬場則男、陣内浩司
    • Journal Title

      顕微鏡

      Volume: 第45巻2号 Pages: 109-113

    • NAID

      130007788958

    • Related Report
      2011 Final Research Report
  • [Journal Article] Extended morphological processing : a practical method for automatic spotdetection of biological markers from microscopic images2010

    • Author(s)
      Y. Kimori, N. Baba and N. Morone
    • Journal Title

      BMC Bioinformatics

      Volume: Vol.11 Pages: 373-385

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Extended morphological processing : a practical method for automatic spot detection of biological markers from microscopic images2010

    • Author(s)
      Y.Kimori1, N.Baba, N.Morone
    • Journal Title

      BMC Bioinformatics

      Volume: 11 Pages: 373-385

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 電子線トモグラフィー法 その2:課題と応用例2010

    • Author(s)
      金子賢治、馬場則男、陣内浩司
    • Journal Title

      顕微鏡

      Volume: 第45巻2号 Pages: 109-113

    • NAID

      130007788958

    • Related Report
      2010 Annual Research Report
  • [Journal Article] Nanostructural characterization and catalytic analysis of hybridized platinum/phthalocyanine nanocomposites2009

    • Author(s)
      K. Kaneko, K. Furuya, A. B. Hungria, J-C. H. Garrido, P. A. Midgley, T. Onodera, H. Kasai, Y. Yaguchi, H. Oikawa, Y. Nomura, H. Harada, T. Ishihara and N. Baba
    • Journal Title

      J. Electron Microsc

      Volume: Vol.58 Pages: 289-294

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Presentation] 電子線CTにおける投影データ欠落に影響されない新たな再構成法2012

    • Author(s)
      馬場則男
    • Organizer
      NINS,画像科学シンポジウム(第2回)・バイオイメージングフォーラム(第6回)合同研究会
    • Place of Presentation
      自然科学研究機構岡崎コンファレンスセンター
    • Year and Date
      2012-03-06
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] 情報欠落に影響されない新たな非線形離散濃度諧調再構成法2011

    • Author(s)
      馬場則男
    • Organizer
      生理学研究所研究会「電子顕微鏡機能イメージングの医学・生物学への応用」
    • Place of Presentation
      岡崎統合バイオサイエンスセンター
    • Year and Date
      2011-12-01
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] 3D電子線トモグラフィーにおける濃度分布特徴に基づく細胞内構造体の抽出法2011

    • Author(s)
      笹島洋輔, 小林博之, 馬場美鈴, 馬場則男
    • Organizer
      第67回日本顕微鏡学会学術講演会
    • Place of Presentation
      福岡国際会議場
    • Year and Date
      2011-05-16
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] 従来法に代わる濃度量子化単位操作による新たな離散非線形再構成法2011

    • Author(s)
      馬場則男
    • Organizer
      第67回日本顕微鏡学会学術講演会
    • Place of Presentation
      福岡国際会議場
    • Year and Date
      2011-05-16
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] 情報欠落のない高スループット電子線トモグラフィを目指す新たな再構成手法2010

    • Author(s)
      馬場則男
    • Organizer
      第26回分析電子顕微鏡討論会
    • Place of Presentation
      幕張メッセ国際会議場
    • Year and Date
      2010-08-31
    • Related Report
      2011 Final Research Report
  • [Presentation] 情報欠落のない高スループット電子線トモグラフィを目指す新たな再構成手法2010

    • Author(s)
      馬場則男
    • Organizer
      第26回分析電子顕微鏡討論会
    • Place of Presentation
      幕張メッセ 国際会議場
    • Year and Date
      2010-08-31
    • Related Report
      2010 Annual Research Report
  • [Presentation] 画像相関および対応点追跡に代わる反復位置合わせ法の検討2010

    • Author(s)
      今村卓馬、馬場則男
    • Place of Presentation
      名古屋国際会議場
    • Year and Date
      2010-05-26
    • Related Report
      2011 Final Research Report 2010 Annual Research Report
  • [Presentation] 微小位相シフト自己相関関数による電子光学パラメータの測定2010

    • Author(s)
      西原佑祐、中村新、友永祥彦、馬場則男
    • Place of Presentation
      名古屋国際会議場
    • Year and Date
      2010-05-25
    • Related Report
      2011 Final Research Report 2010 Annual Research Report
  • [Presentation] A novel method of reconstructing a tomogram by convergence of an innumerable dots map without the "Missing-Wedge" effect2009

    • Author(s)
      N. Baba and E. Katayama
    • Organizer
      FEMMS2009(Frontiers of Electron Microscopy in Materials Science)
    • Place of Presentation
      Nagasaki
    • Year and Date
      2009-10-02
    • Related Report
      2011 Final Research Report
  • [Presentation] A novel method of reconstructing a tomogram by convergence of an innumerable dots map without the "Missing-Wedge" effect2009

    • Author(s)
      N.Baba, E.Katayama
    • Organizer
      FEMMS2009(Frontiers of Electron Microscopy in Materials Science)
    • Place of Presentation
      HUIS TEN BOSCH, Nagasaki
    • Year and Date
      2009-10-02
    • Related Report
      2009 Annual Research Report
  • [Presentation] 電子線トモグラフィーにおける3次元再構成法の現状2009

    • Author(s)
      馬場則男
    • Organizer
      日本鉄鋼協会・第158回秋季講演大会シンポジウム
    • Place of Presentation
      京都大学
    • Year and Date
      2009-09-16
    • Related Report
      2011 Final Research Report 2009 Annual Research Report
  • [Presentation] 収束性を高めた微小点密度分布再構成法2009

    • Author(s)
      馬場則男, 片山栄作
    • Organizer
      第65回日本顕微鏡学会学術講演会
    • Place of Presentation
      仙台国際センター
    • Year and Date
      2009-05-27
    • Related Report
      2011 Final Research Report 2009 Annual Research Report
  • [Patent(Industrial Property Rights)] 特許権2010

    • Inventor(s)
      馬場則男、久保貴、橋本隆仁、矢口紀恵
    • Industrial Property Rights Holder
      (株)日立ハイテクノロジーズ
    • Filing Date
      2010-07-15
    • Related Report
      2011 Final Research Report
  • [Patent(Industrial Property Rights)] 特許権2010

    • Inventor(s)
      馬場則男、久保貴、橋本隆仁、矢口紀恵
    • Industrial Property Rights Holder
      (株)日立ハイテクノロジーズ
    • Filing Date
      2010-07-15
    • Related Report
      2010 Annual Research Report

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Published: 2009-04-01   Modified: 2016-04-21  

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