| Project/Area Number |
21340066
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Particle/Nuclear/Cosmic ray/Astro physics
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| Research Institution | Waseda University |
|---|
Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
WASHIO Masakazu 早稲田大学, 理工学術院, 教授 (70158608)
|
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| Co-Investigator(Renkei-kenkyūsha) |
KONDOH Takeshi 神戸大学, 医学部, 医学研究員 (50273769)
NARIYAMA Nobuteru (財)高輝度光科学研究センター, 光源光学系部門, 研究員 (20344393)
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥19,500,000 (Direct Cost: ¥15,000,000、Indirect Cost: ¥4,500,000)
Fiscal Year 2011: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2010: ¥6,240,000 (Direct Cost: ¥4,800,000、Indirect Cost: ¥1,440,000)
Fiscal Year 2009: ¥11,180,000 (Direct Cost: ¥8,600,000、Indirect Cost: ¥2,580,000)
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| Keywords | 放射線治療法 / 加速器 / 微小平板ビーム / モンテカルロコード / ガフクロミックフィルム / 顕微分光 / マイクロドシメトリー / グリオーマ / 徴小平板ビーム / 高エネルギーX線 / マイクロアレイ解析 |
|---|
| Research Abstract |
A study on microplanar beam radiation therapy(MRT) has demonstrated the following points : for the animal study at SPring-8, alignment of a collimator is very important to obtain a symmetrical beam profile for irradiation ; hypoxic fraction of tumor cells after MRT treatment was increased, which may explain the selective killing of tumor cells by MRT ; as for a beam width, narrow beam was more effective than wider beam, which suggests that an appropriate beam width must be exist ; and for the X-ray energy, high energy such as 1 MeV was not applicable and the most effective energy will be in the range of 100-250 keV.
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