| Project/Area Number |
21340067
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Particle/Nuclear/Cosmic ray/Astro physics
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| Research Institution | Kobe Tokiwa University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
FUJIWARA Mamoru 大阪大学, 核物理研究センター, 准教授 (00030031)
KOHRI Hideki 大阪大学, 核物理研究センター, 助教 (40448022)
TAKAMATSU Kunihiko 神戸常盤大学・短期大学部, 口腔保健学科, 助教 (80392017)
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥18,980,000 (Direct Cost: ¥14,600,000、Indirect Cost: ¥4,380,000)
Fiscal Year 2011: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Fiscal Year 2010: ¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2009: ¥10,790,000 (Direct Cost: ¥8,300,000、Indirect Cost: ¥2,490,000)
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| Keywords | 超偏極MRI / 強制偏極法 / 高速融解法 / 核スピンイメージング / ポメランチュクセル / ^3He/^4He希釈冷凍機 / 超偏極^3He-MRI / ポメランチュク冷却 / 液体^3HeのNMRスペクトル / MRI / 急速融解 / Brute force method / COPD(慢性閉塞性肺疾患) / ^3He / ^4He希釈冷凍機 / 熱スイッチ |
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| Research Abstract |
We have developed a method to create the hyperpolarized, i. e., highly polarized^3He gas for the^3He-MRI using the Brute Force Method(BFM), where an extremely low temperature(～ 10mK), and a strong magnetic field(～ 17T) are employed. The reason why we use the BFM is that the production rate of the hyperpolarized^3He created by the well established laser optical pumping is limited to about 1 liter/day, while that for the BFM is expected to exceed 1000 liter/day.
Currently, we use the^3He/^4He cryogenic system(DRS2500) introduced from the Leiden Cryogenics, the Netherlands to realize a temperature lower than 10mK together with a Pomeranchuk cell, and the superconducting solenoidal coil to realize a strong magnetic field of 17T. We are almost ready to check the validity of the vaporization of the hyperpolarized solid^3He through a liquid phase without sizable spin relaxation by use of a method called a rapid melting method. We have started a preliminary experiment toward the production of the hyperpolarized^3He gas.
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