| Budget Amount *help |
¥18,460,000 (Direct Cost: ¥14,200,000、Indirect Cost: ¥4,260,000)
Fiscal Year 2012: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Fiscal Year 2011: ¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2010: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2009: ¥5,720,000 (Direct Cost: ¥4,400,000、Indirect Cost: ¥1,320,000)
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| Research Abstract |
Behaviors of traveling excitation waves around obstacle region in cultivated cardiomyocytes were investigated in experimentally and numerically. The instability of propagation waves were affected by excitability of the cells and shape of obstacle.Spontaneous formation of spiral wave at edge of sharp corner was also observed.Furthermore, new methods (1) to control activity of cardiomyocytes with the aid of photo-switching molecules, and (2) to construct aligned culture of cells along fabricated microfiber were established
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