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Nerve cell tissue activation by a low invasion type micro spot atmospheric pressure plasma source

Research Project

Project/Area Number 21340173
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Plasma science
Research InstitutionTokyo City University

Principal Investigator

HIRATA Takamichi  東京都市大学, 工学部, 准教授 (80260420)

Co-Investigator(Kenkyū-buntansha) SHIMATANI Yuichi  東京都市大学, 工学部, 准教授 (20154263)
HATAKEYAMA Rikizo  東北大学, 工学(系)研究科(研究院), 教授 (00108474)
Project Period (FY) 2009 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥17,680,000 (Direct Cost: ¥13,600,000、Indirect Cost: ¥4,080,000)
Fiscal Year 2011: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2010: ¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2009: ¥8,840,000 (Direct Cost: ¥6,800,000、Indirect Cost: ¥2,040,000)
Keywords大気圧プラズマ / 成長因子 / プラズマ吸入 / 大気圧プラズマ源 / プラズマ照射 / プラズマ-液相界面 / 細胞増殖 / 一酸化窒素(NO) / NO合成酵素(NOS) / マイクロスポット照射 / 表面改質・活性 / プラズマー液相界面
Research Abstract

According to the typical microscope images of culture cells, healthy growth was observed for plasma irradiation. Furthermore, in an experiment testing the effects of plasma irradiation on rats that were artificially given burn wounds, no evidence of electric shock injuries was found in the irradiated areas. In fact, the observed evidence of healing and improvements of the burn wounds. Therefore, it appears that the interaction due to ion/radical collisions on the culture surface causes a substantial effect on the proliferation of growth factors.

Report

(4 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • 2009 Annual Research Report
  • Research Products

    (44 results)

All 2012 2011 2010 2009 Other

All Journal Article (9 results) (of which Peer Reviewed: 7 results) Presentation (26 results) Book (2 results) Remarks (7 results)

  • [Journal Article] Fat liquefaction of adipose tissue using atmospheric-pressure plasma irradiation2011

    • Author(s)
      T. Hirata, C. Tsutsui, T. Kishimoto, A. Mori, M. Akiya, T. Yamamoto, and A. Taguchi
    • Journal Title

      Japanese Journal of Applied Physics

      Volume: Vol.50, No.8 Pages: 80217-80217

    • NAID

      40018960979

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Non-invasive measurement of fetal augmentation index by fetal aortic diameter pulse and flow velocity waveforms2011

    • Author(s)
      A. Mori, A. Kondo, T. Hirata, and C. Tsutsui
    • Journal Title

      Acta Obstetricia et Gynecologica Scandinavica

      Volume: Vol.90, Issue 8 Pages: 839-845

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] マイクロスポット大気圧プラズマ源による細胞および生体組織の活性化2011

    • Author(s)
      筒井千尋、平田孝道、小町俊文、岸本拓巳、森晃、秋谷昌宏、山本俊昭、田口亮
    • Journal Title

      静電気学会誌

      Volume: 第35巻、第1号 Pages: 20-24

    • NAID

      10027798673

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Fat liquefaction of adipose tissue using atmospheric-pressure plasma irradiation2011

    • Author(s)
      T.Hirata, et al
    • Journal Title

      Japanese Journal of Applied Physics

      Volume: 50 Issue: 8R Pages: 080217-080217

    • DOI

      10.1143/jjap.50.080217

    • NAID

      40018960979

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Non-invasive measurement of fetal augmentation index by fetal aortic diameter pulse and flow velocity waveforms2011

    • Author(s)
      A.Mori, et al
    • Journal Title

      Acta Obstetricia et Gynecologica Scandinavica

      Volume: 90 Issue: 8 Pages: 839-845

    • DOI

      10.1111/j.1600-0412.2011.01173.x

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] マイクロスポット大気圧プラズマ源による細胞および生体組織の活性化2011

    • Author(s)
      筒井, 他
    • Journal Title

      静電気学会誌

      Volume: 35 Pages: 20-24

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] カーボンナノチューブ(CNT)を用いた抗原-抗体センサの応用2010

    • Author(s)
      舟田, 他
    • Journal Title

      電気学会論文誌E

      Volume: 130 Pages: 543-549

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Direct Measurement of Nitric Oxide Produced from Cell Under the Atmospheric Pressure Plasma Irradiation2010

    • Author(s)
      T.Hirata, et al.
    • Journal Title

      Proceedings of the 7th International Conference on Reactive Plasmas (ICRP-7)/63rd Gaseous Electronics Conference (GEC-63)/28th Symposium on Plasma Processing (SPP-28)

    • Related Report
      2010 Annual Research Report
  • [Journal Article] Micro-Spot Atmospheric Pressure Plasma Production for the Biomedical Applications2009

    • Author(s)
      T.Hirata, et al.
    • Journal Title

      Proceedings of the Sixth Asia-Pacific International Symposium on the Basic and Application of Plasma Technology (APSPT-6)

    • Related Report
      2009 Annual Research Report
  • [Presentation] マイクロスポット大気圧プラズマ源を用いた生体組織再生の検討2012

    • Author(s)
      小町俊文、筒井千尋、平田孝道、秋谷昌宏
    • Organizer
      第59回応用物理学関係連合講演会
    • Place of Presentation
      早稲田大学
    • Year and Date
      2012-03-17
    • Related Report
      2011 Final Research Report
  • [Presentation] マイクロスポット大気圧プラズマ源を用いた再生医療(5)2012

    • Author(s)
      岸本拓巳、筒井千尋、平田孝道、森晃、秋谷昌宏
    • Organizer
      第59回応用物理学関係連合講演会
    • Place of Presentation
      早稲田大学
    • Year and Date
      2012-03-17
    • Related Report
      2011 Final Research Report
  • [Presentation] 大気圧プラズマ源から発生したプラズマの吸入による疾患治療2012

    • Author(s)
      平田孝道、村田茂、筒井千尋、近藤朱音、森晃
    • Organizer
      第59回応用物理学関係連合講演会
    • Place of Presentation
      早稲田大学
    • Year and Date
      2012-03-17
    • Related Report
      2011 Final Research Report
  • [Presentation] 大気圧プラズマ源から発生したプラズマの吸入による疾患治療2012

    • Author(s)
      平田孝道, 他
    • Organizer
      第59回応用物理学関係連合講演会
    • Place of Presentation
      早稲田大学、東京
    • Year and Date
      2012-03-17
    • Related Report
      2011 Annual Research Report
  • [Presentation] マイクロスポット大気圧プラズマ源を用いた再生医療(5)2012

    • Author(s)
      岸本拓巳, 他
    • Organizer
      第58回応用物理学関係連合講演会
    • Place of Presentation
      早稲田大学、東京
    • Year and Date
      2012-03-17
    • Related Report
      2011 Annual Research Report
  • [Presentation] Regenerative Medicine Using Novel Biomedical Plasma Techniques2011

    • Author(s)
      T. Hirata, C. Tsutsui, and A. Mori
    • Organizer
      The Eighth International Conference on Flow Dynamics(ICFD)
    • Place of Presentation
      Sendai/Japan
    • Year and Date
      2011-11-10
    • Related Report
      2011 Final Research Report
  • [Presentation] Regenerative Medicine Using Novel Biomedical Plasma Techniques2011

    • Author(s)
      T.Hirata, et al
    • Organizer
      The Eighth International Conference on Flow Dynamics (ICFD)
    • Place of Presentation
      Hotel Metropolitan Sendai/Japan(招待講演)
    • Year and Date
      2011-11-05
    • Related Report
      2011 Annual Research Report
  • [Presentation] マイクロスポットプラズマ源による血管新生促進メカニズム2011

    • Author(s)
      筒井千尋、平田孝道、横井由貴子、小町俊文、岸本巧巳、村田茂、森晃、秋谷昌宏、山本俊昭、田口亮
    • Organizer
      第35回静電気学会全国大会
    • Place of Presentation
      東京理科大学
    • Year and Date
      2011-09-13
    • Related Report
      2011 Final Research Report
  • [Presentation] 大気圧非熱平衡プラズマを用いた細胞の活性化・不活性化2011

    • Author(s)
      猪股茂、平田孝道、筒井千尋、江原由泰、山本俊昭
    • Organizer
      第35回静電気学会全国大会
    • Place of Presentation
      東京理科大学
    • Year and Date
      2011-09-13
    • Related Report
      2011 Final Research Report
  • [Presentation] マイクロスポットプラズマ源による血管新生促進メカニズム2011

    • Author(s)
      筒井千尋, 他
    • Organizer
      第35回静電気学会全国大会
    • Place of Presentation
      東京理科大学、東京
    • Year and Date
      2011-09-13
    • Related Report
      2011 Annual Research Report
  • [Presentation] Biomedical Plasma for the Regenerative Medicine Applications2011

    • Author(s)
      T. Hirata, C. Tsutsui, T. Komachi, T. Kishimoto, A. Mori, M. Akiya, T. Yamamoto, and A. Taguchi
    • Organizer
      The 3rd International Conference on Microelectronics and Plasma Technology(ICMAP-2011)
    • Place of Presentation
      Dalian/China
    • Year and Date
      2011-07-06
    • Related Report
      2011 Final Research Report
  • [Presentation] Biomedical Plasma for the Regenerative Medicine Applications2011

    • Author(s)
      T.Hirata, et al
    • Organizer
      The 3rd International Conference on Microelectronics and Plasma Technology (ICMAP-2011)
    • Place of Presentation
      Dalian/China(招待講演)
    • Year and Date
      2011-07-06
    • Related Report
      2011 Annual Research Report
  • [Presentation] マイクロスポット大気圧プラズマ源を用いた再生治療(4)2011

    • Author(s)
      平田孝道、筒井千尋、小町俊文、岸本拓巳、佐藤和子、森晃、山本俊昭、秋谷昌宏、田口亮
    • Organizer
      第58回応用物理学関係連合講演会
    • Place of Presentation
      神奈川工科大学
    • Year and Date
      2011-03-25
    • Related Report
      2011 Final Research Report
  • [Presentation] マイクロスポット大気圧プラズマ源を用いた再生治療(4)2011

    • Author(s)
      平田, 他
    • Organizer
      第58回応用物理学関係連合講演会
    • Place of Presentation
      神奈川工科大学、神奈川県
    • Year and Date
      2011-03-05
    • Related Report
      2010 Annual Research Report
  • [Presentation] Activation of Cell Irradiated by An Atmospheric-Pressure Plasma for the Biomedical Applications2010

    • Author(s)
      T. Hirata, C. Tsutsui, T. Komachi, T. Kishimoto, Y. Sakatani, A. Mori, M. Akiya, T. Yamamoto, and A. Taguchi
    • Organizer
      American Vacuum Society(AVS) 57th International Symposium & Exhibition
    • Place of Presentation
      Albuquerque, New Mexico/USA
    • Year and Date
      2010-10-20
    • Related Report
      2011 Final Research Report
  • [Presentation] Activation of Cell Irradiated by An Atmospheric-Pressure Plasma for the Biomedical Applications2010

    • Author(s)
      T.Hirata, et al.
    • Organizer
      American Vacuum Society (AVS) 57th International Symposium & Exhibition
    • Place of Presentation
      アルバカーキー,ニューメキシコ州,米国(招待講演)
    • Year and Date
      2010-10-15
    • Related Report
      2010 Annual Research Report
  • [Presentation] Direct Measurement of Nitric Oxide Produced from Cell Under the Atmospheric Pressure Plasma Irradiation2010

    • Author(s)
      T. Hirata, C. Tsutsui, T. Komachi, T. Kishimoto, A. Mori, T. Yamamoto, M. Akiya, and A. Taguchi
    • Organizer
      The 7th International Conference on Reactive Plasmas(ICRP-7)/63rd Gaseous Electronics Conference(GEC-63)/28th Symposium on Plasma Processing(SPP-28)
    • Place of Presentation
      Paris/France
    • Year and Date
      2010-10-06
    • Related Report
      2011 Final Research Report
  • [Presentation] マイクロスポット大気圧プラズマ源を用いた再生治療(3)2010

    • Author(s)
      平田, 他
    • Organizer
      第71回応用物理学会学術講演会
    • Place of Presentation
      長崎大学、長崎県
    • Year and Date
      2010-09-15
    • Related Report
      2010 Annual Research Report
  • [Presentation] マイクロスポット大気圧プラズマ源による細胞および生体組織の活性化2010

    • Author(s)
      筒井千尋、平田孝道、横井由貴子、小町俊文、岸本巧巳、村田茂、澤田佳那子、佐藤和子、森晃、猪俣茂、杉原悠公、鈴木雄一郎、山本俊昭、田口亮
    • Organizer
      第34回静電気学会全国大会
    • Place of Presentation
      鳥取大学
    • Year and Date
      2010-09-06
    • Related Report
      2011 Final Research Report
  • [Presentation] Micro-Spot Atmospheric Pressure Plasma Production for the Bio-Medical Application2010

    • Author(s)
      T.Hirata, et al.
    • Organizer
      The 11th International Workshop of Advanced Plasma Processing and Diagnostics
    • Place of Presentation
      済州島、韓国(基調講演)
    • Year and Date
      2010-07-09
    • Related Report
      2010 Annual Research Report
  • [Presentation] Micro-Spot Atmospheric Pressure Plasma Production for the Bio-Medical Application2010

    • Author(s)
      T. Hirata, C. Tsutsui, A. Mori, T. Yamamoto, M. Akiya, A. Taguchi
    • Organizer
      The 11th International Workshop of Advanced Plasma Processing and Diagnostics
    • Place of Presentation
      Jeju/Korea
    • Year and Date
      2010-07-08
    • Related Report
      2011 Final Research Report
  • [Presentation] マイクロスポット大気圧プラズマ源を用いた再生治療(1)2010

    • Author(s)
      平田孝道、筒井千尋、坂谷祐一郎、森晃、堀井敦史、山本俊昭、田口亮
    • Organizer
      第57回応用物理学関係連合講演会
    • Place of Presentation
      東海大学
    • Year and Date
      2010-03-19
    • Related Report
      2011 Final Research Report
  • [Presentation] 大気圧放電プラズマ源を用いた生体組織の再生治療2010

    • Author(s)
      筒井千尋、平田孝道、森晃、山本俊昭、田口亮
    • Organizer
      ナノ・バイオメディカル学会第2回大会
    • Place of Presentation
      大阪大学
    • Year and Date
      2010-02-22
    • Related Report
      2011 Final Research Report
  • [Presentation] Micro-Spot Atmospheric Pressure Plasma Production for the Biomedical Applications2009

    • Author(s)
      T. Hirata, C. Tsutsui, Y. Yokoi, Y. Sakatani, A. Mori, A. Horii, T. Yamamoto, and A. Taguchi
    • Organizer
      The Sixth Asia-Pacific International Symposium on the Basic and Application of Plasma Technology(APSPT-6)
    • Place of Presentation
      Hsinchu/Taiwan
    • Year and Date
      2009-12-15
    • Related Report
      2011 Final Research Report
  • [Presentation] Medical Treatment and Cell Activation Using Micro-Spot Atmospheric Pressure Plasma2009

    • Author(s)
      T.Hirata, et al.
    • Organizer
      第19回 日本MRS学術シンポジウム(MRS-J)
    • Place of Presentation
      横浜市開港記念会館
    • Year and Date
      2009-12-07
    • Related Report
      2009 Annual Research Report
  • [Presentation] マイクロスポット大気圧プラズマ源を用いた生体組織・細胞の活性化2009

    • Author(s)
      平田孝道、筒井千尋、横井由貴子、坂谷祐一郎、森晃、堀井敦史、山本俊昭、田口亮
    • Organizer
      第33回静電気学会全国大会
    • Place of Presentation
      東京都市大学
    • Year and Date
      2009-09-10
    • Related Report
      2011 Final Research Report
  • [Book] 大気圧プラズマの技術とプロセス開発2011

    • Author(s)
      平田孝道
    • Publisher
      シーエムシー出版
    • Related Report
      2011 Final Research Report
  • [Book] 大気圧プラズマの技術とプロセス開発2011

    • Author(s)
      沖野晃俊監修
    • Publisher
      シーエムシー出版
    • Related Report
      2011 Annual Research Report
  • [Remarks]

    • URL

      http://www.bme.tcu.ac.jp/index.html

    • Related Report
      2011 Final Research Report
  • [Remarks]

    • URL

      http://www.bme.tcu.ac.jp/rmct/top.html

    • Related Report
      2011 Final Research Report
  • [Remarks]

    • URL

      http://www.bme.tcu.ac.jp/index.html

    • Related Report
      2011 Annual Research Report
  • [Remarks]

    • URL

      http://www.bme.tcu.ac.jp/rmct/top.html

    • Related Report
      2011 Annual Research Report
  • [Remarks]

    • URL

      http://www.bme.tcu.ac.jp/lab/03/

    • Related Report
      2010 Annual Research Report
  • [Remarks]

    • URL

      http://www.bme.tcu.ac.jp/rmct/

    • Related Report
      2010 Annual Research Report
  • [Remarks]

    • URL

      http://www.bme.tcu.ac.jp/lab/03/

    • Related Report
      2009 Annual Research Report

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Published: 2009-04-01   Modified: 2016-04-21  

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