Control of a small amount of molecules in two-dimensional monolayer by local modification
| Project/Area Number |
21350001
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Physical chemistry
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| Research Institution | Hokkaido University |
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Principal Investigator |
MURAKOSHI Kei 北海道大学, 大学院・理学研究院, 教授 (40241301)
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| Co-Investigator(Kenkyū-buntansha) |
NABIKA Hideki 北海道大学, 大学院・理学研究院, 助教 (30372262)
YASUDA Satoshi 北海道大学, 大学院・理学研究院, 講師 (90400639)
池田 勝佳 北海道大学, 大学院・理学研究院, 准教授 (50321899)
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥19,630,000 (Direct Cost: ¥15,100,000、Indirect Cost: ¥4,530,000)
Fiscal Year 2011: ¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2010: ¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2009: ¥10,270,000 (Direct Cost: ¥7,900,000、Indirect Cost: ¥2,370,000)
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| Keywords | 脂質二分子膜 / 蛍光標識脂質分子 / 全反射顕微鏡 / 分子フィルター / ゲート構造 / 微小ギャップ / 単一分子追跡 / ナノゲート / フィルタ効果 / 透過確率 / 脂質二重膜 / 局所構造制御 / 分子トラッピング / 単一分子分光 / 分子分別場 |
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| Research Abstract |
We revealed that molecules with distinct sizes and strictures in self-spreading lipid bilayer are selectively filtered when the bilayer spread through the metallic nanogates. In order to make clear the origin of this molecular filtering phenomenon, we have observed molecular diffusion in nano space by single molecular tracking. In this research, metal nanogates with sizes of 100 nm was fabricated on cover slips with using electron beam lithography. The quantitative evaluation by single molecular tracking can reveal that the structural change of lipid bilayer correlates molecular diffusion change in nano space.
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Report
(4 results)
Research Products
(52 results)
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[Journal Article] Phosphine Sulfides as an Anchor Unit for Single Molecule Junction2011
Author(s)
Aiko Fukazawa, Manabu Kiguchi, Satoshi Tange, Yasunori Ichihashi, Qiang Zhao, Takuya Takahashi, Tatsuya Konishi, Kei Murakoshi, Yuta Tsuji, Alekandar Staykov, Kazunari Yoshizawa, Shigehiro Yamaguchi
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Journal Title
Chemistry Letters
Volume: 2
Pages: 174-174
NAID
Related Report
Peer Reviewed
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