| Budget Amount *help |
¥18,980,000 (Direct Cost: ¥14,600,000、Indirect Cost: ¥4,380,000)
Fiscal Year 2011: ¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2010: ¥6,110,000 (Direct Cost: ¥4,700,000、Indirect Cost: ¥1,410,000)
Fiscal Year 2009: ¥8,190,000 (Direct Cost: ¥6,300,000、Indirect Cost: ¥1,890,000)
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| Research Abstract |
In the" omics" era, there is a great need for comprehensive genome-wide multi-element analysis of a single cell and organism, because the combination of different metals and metalloids may exhibit an additive, synergistic, or antagonistic effect on cellular functions. Thus, we have had an intense interest in determining what kind of and how many elements are involved in cells, organs and organisms. In this paper, we have carried out multielement analysis of single celled bacteria(Escherichia coli) and organism(euglena) as well as embryos of chum salmon at different stages of development. The experimental results revealed that trace elements were to some extent selectively transferred from the culture media(or yolk sac) to the cell(or embryonic body) at an appropriate timing.
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