Development of a Novel Conductivity Detection Technique using Microbeads Coated with Gold Nanoparticles
| Project/Area Number |
21350044
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Analytical chemistry
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| Research Institution | Osaka Prefecture University |
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Principal Investigator |
NAGAOKA Tsutomu 大阪府立大学, 大学院・工学研究科, 教授 (00172510)
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| Co-Investigator(Renkei-kenkyūsha) |
SHIIGI Hiroshi 大阪府立大学, 工学研究科, 准教授 (70335769)
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥19,370,000 (Direct Cost: ¥14,900,000、Indirect Cost: ¥4,470,000)
Fiscal Year 2011: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2010: ¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2009: ¥11,050,000 (Direct Cost: ¥8,500,000、Indirect Cost: ¥2,550,000)
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| Keywords | 化学センサ / 金ナノ粒子 / マイクロビーズ / 樹脂マイクロビーズ / ナノ粒子被覆ビーズ / DNA / 磁性樹脂ビーズ / 酵素 / 電気的検出 / ナノ粒子被覆マイクロビーズ / 電流検出 / 金メッキビーズ / 磁性樹脂マイクロビーズ / 導電性ポリマー / 過酸化 |
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| Research Abstract |
In this research project, we have developed a novel detection system using plastic microbeads, which was coated with gold nanoparticles. The gold nanoparticle coated beads had an electrical conductivity ranging from 30 to a few mega ohm, and ligand coating was made on the gold layer by the self-assembly process. We have confirmed that the formation of a ligand-analyte linkage led to an increase in the electrical resistance of the microbeads.
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Report
(4 results)
Research Products
(39 results)
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[Presentation] 金被覆バイオビーズの作製2010
Author(s)
宮下尚之, 水谷祐太, 山本陽二郎, 床波志保, 椎木弘, 長岡勉
Organizer
第71回分析化学討論会
Place of Presentation
松江
Year and Date
2010-05-16
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