Determining the regulons and their functions in hyperthermophiles
Project/Area Number |
21350092
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Research Category |
Grant-in-Aid for Scientific Research (B)
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Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Chemistry related to living body
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Research Institution | Kyoto University |
Principal Investigator |
ATOMI Haruyuki 京都大学, 大学院・工学研究科, 教授 (90243047)
|
Project Period (FY) |
2009 – 2011
|
Project Status |
Completed (Fiscal Year 2011)
|
Budget Amount *help |
¥19,110,000 (Direct Cost: ¥14,700,000、Indirect Cost: ¥4,410,000)
Fiscal Year 2011: ¥6,500,000 (Direct Cost: ¥5,000,000、Indirect Cost: ¥1,500,000)
Fiscal Year 2010: ¥6,500,000 (Direct Cost: ¥5,000,000、Indirect Cost: ¥1,500,000)
Fiscal Year 2009: ¥6,110,000 (Direct Cost: ¥4,700,000、Indirect Cost: ¥1,410,000)
|
Keywords | 転写制御因子 / 遺伝子破壊 / regulon / 超好熱菌 / 始原菌 / ゲノム / Thermococcus kodakarensis / プロモーター / Thermococcus kodakaraensis / 機能未知遺伝子 |
Research Abstract |
We have previously determined the complete genome sequence of the hyperthermophilic archaeon Thermococcus kodakarensis, and have also established a gene disruption and transcriptome analysis system for this organism. Using this information/technology, we disrupted genes predicted to encode transcription regulation factors. This project has led to the elucidation of multiple regulons, and we have been able to propose the functions of genes in several regulons.
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Report
(4 results)
Research Products
(23 results)
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[Journal Article] Identification of the Phr-dependent heat shock regulon in the hyperthermophilic arch eon, Thermococcus kodakaraensis2010
Author(s)
Kanai, T., Takedomi, S., Fujiwara, S., Atomi, H., Imanaka, T.
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Journal Title
Journal of Biochemistry
Volume: 147(3)
Pages: 361-370
Related Report
Peer Reviewed
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[Journal Article] Identification of the Phr-dependent heat shock regulon in the hyperthermophilic archaeon, Thermococcus kodakaraensis.2010
Author(s)
Kanai, T., Takedomi, S., Fujiwara, S., Atomi, H., Imanaka, T.
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Journal Title
Journal of Biochemistry
Volume: 147
Pages: 361-370
NAID
Related Report
Peer Reviewed
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[Journal Article]2010
Author(s)
跡見晴幸, 小宮山眞 監修
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Journal Title
酵素利用技術大系―基礎・解析から改変・高機能化・産業利用まで―(株式会社エヌ・ティー・エス)
Pages: 510-517
Related Report
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