Development of new DNA duplex-based materials for detecting and removing heavy metal ions in aqueous solutions.
| Project/Area Number |
21350105
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Functional materials/Devices
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| Research Institution | Kanagawa University |
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Principal Investigator |
ONO Akira 神奈川大学, 工学部, 教授 (10183253)
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| Co-Investigator(Kenkyū-buntansha) |
OKAMOTO Itaru 神奈川大学, 工学部, 特別助教 (40460133)
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥15,470,000 (Direct Cost: ¥11,900,000、Indirect Cost: ¥3,570,000)
Fiscal Year 2011: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2010: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2009: ¥8,580,000 (Direct Cost: ¥6,600,000、Indirect Cost: ¥1,980,000)
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| Keywords | DNA / 透過膜 / 金属イオン検出 / 環境材料 / 水質浄化 / チミン結合高分子 / 重金属イオン / 金属イオンセンサー / オリゴヌクレオチド / Ag(I)イオン / Hg(II)イオン / チオウラシル / ピレン / 水銀イオン / Cu(II)イオン / 金ナノ粒子 / Hg(II) |
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| Research Abstract |
In order to develop noblemethods for selectively binding Hg(II) ions in aqueous solutions, we synthesized polymers carrying thymine (uracil) residues of which Hg(II) binding activities were low. Thymine (uracil) dimer, in which two pyrimidine bases were connected by alkyl linker showed good Hg(II) ions binding activity. Polymers carrying the pyrimidine dimer residues also showed goog Hg(II) ions binding activities. Through a liquidmembranecontaining thymine with long alkyl chain, Hg(II) ions were selectively penetrated.
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Report
(4 results)
Research Products
(56 results)
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[Journal Article] Raman spectroscopic detection of the T-HgII-T base pair and the ionic characteristics of mercury2012
Author(s)
Tomomi Uchiyama, Takashi Miura, Hideo Takeuchi, Takenori Dairaku, Tomoyuki Komuro, Takuya Kawamura, Yoshinori Kondo, Ladislav Benda, Vladimir Sychrovsky, Petr Bour, Itaru Okamoto, Akira Ono and Yoshiyuki Tanaka
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Journal Title
Nucleic Acids Res
Volume: 40
Issue: 12
Pages: 5766-5774
DOI
Related Report
Peer Reviewed
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