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Electrical Conducting LB films as soft electrode and the application for biosensor

Research Project

Project/Area Number 21360006
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Applied materials science/Crystal engineering
Research InstitutionTokyo University of Marine Science and Technology

Principal Investigator

OHNUKI Hitoshi  東京海洋大学, 海洋科学技術研究科, 助教 (60223898)

Co-Investigator(Renkei-kenkyūsha) ENDO Hideaki  東京海洋大学, 海洋科学技術研究科, 教授 (50242326)
IMAKUBO Tatsuro  長岡科学技術大学, 工学部, 準教授 (60291332)
IZUMI Mitsuru  東京海洋大学, 海洋科学技術研究科, 教授 (50159802)
Project Period (FY) 2009 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥12,090,000 (Direct Cost: ¥9,300,000、Indirect Cost: ¥2,790,000)
Fiscal Year 2011: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Fiscal Year 2010: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2009: ¥6,240,000 (Direct Cost: ¥4,800,000、Indirect Cost: ¥1,440,000)
Keywordsバイオエレクトロニクス / 導電性有機薄膜 / 自己組織化膜 / バイオセンサ / 酵素 / 電気化学インピーダンス法 / くし型電極 / トンネル電流 / ラングミュア・ブロジェット膜 / 有機伝導体
Research Abstract

The Langmuir-Blodgett(LB) technique or self-assembled monolayer(SAM) allows to form ultra-thin films on the soft materials such as biological functional proteins or nano-sturucure substances, without damaging their functions. In this research, we have developed the methods establishing electrical contact to soft materials by employing electrical conducting LB films and SAMs. Applying these methods, we have fabricated several new devices including biosensors and molecular devices.

Report

(4 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • 2009 Annual Research Report
  • Research Products

    (32 results)

All 2012 2011 2010 2009 Other

All Journal Article (9 results) (of which Peer Reviewed: 8 results) Presentation (20 results) Remarks (1 results) Patent(Industrial Property Rights) (2 results)

  • [Journal Article] Effects of self-assembled monolayers on amperometric glucose biosensors based on an organic-inorganic hybrid system2012

    • Author(s)
      Huihui Wang, Hitoshi Ohnuki, Hideaki Endo, Mitsuru Izumi
    • Journal Title

      Sens. Actuators B : Chem.

      Volume: 168 Pages: 249-255

    • DOI

      10.1016/j.snb.2012.04.018

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Journal Article]2011

    • Author(s)
      T. Muramatsu, H. Ohnuki, H. Ushio, K. Hibi, M. Igarashi, T. Hayashi, H. Ren, and H. Endo
    • Journal Title

      Int. J. Environ. Anal. Chem.

      Volume: Vol.91 Issue: 2 Pages: 161-173

    • DOI

      10.1080/03067319.2010.500725

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Thin Film Biosensor Based on Organic-inorganic Hybrid System2011

    • Author(s)
      Huihui Wang, Hitoshi Ohnuki, Hideaki Endo, and Mitsuru Izumi
    • Journal Title

      Transactions of the Materials Research Society of Japan

      Volume: Vol.36 Pages: 161-164

    • NAID

      130005004118

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Preparation of Amperometric Glucose Biosensor Based on 4-Mercaptobenzoic Acid2011

    • Author(s)
      Huihui Wang, Hitoshi Ohnuki, Hideaki Endo, and Mitsuru Izumi
    • Journal Title

      Physics Procedia

      Volume: vol.14 Pages: 2-6

    • DOI

      10.1016/j.phpro.2011.05.003

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Organic-Inorganic Hybrid Ultra-Thin Films Applied to Glucose Biosensor2011

    • Author(s)
      Huihui Wang, Hitoshi Ohnuki, Hideaki Endo, and Mitsuru Izumi
    • Journal Title

      IEICE Transactions on Electronics

      Volume: E94-C Issue: 12 Pages: 1855-1857

    • DOI

      10.1587/transele.E94.C.1855

    • NAID

      10030537687

    • ISSN
      0916-8524, 1745-1353
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Thin Film Biosensor Based on Organic-inorganic Hybrid System2011

    • Author(s)
      Huihui Wang, Hitoshi Ohnuki, Hideaki Endo, Mitsuru Izumi
    • Journal Title

      Transactions of the Materials Research Society of Japan

      Volume: 36 Pages: 161-164

    • NAID

      130005004118

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 有機-無機ハイブリッド超薄膜によるバイオセンサの開発2010

    • Author(s)
      大貫等、遠藤英明、今久保達郎、和泉充
    • Journal Title

      電気学会論文誌A

      Volume: Vol.130 Pages: 141-146

    • NAID

      10026225166

    • URL

      https://www.jstage.jst.go.jp/FF01S040Init/-char/ja/?sourceurl=%2Farticle%2Fieejfm%2F130%2F2%2F130_2_141%2F_pdf

    • Related Report
      2011 Final Research Report 2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Preparation of amperometric biosensor based on organic-inorganic hybrid system2010

    • Author(s)
      Huihui Wang, Mitsuru Izumi, Hideaki Endo, and Hitoshi Ohnuki
    • Journal Title

      Transactions of the Materials Research Society of Japan

      Volume: Vol.35 Pages: 327-330

    • NAID

      130003398933

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Preparation of amperometric biosensor based on organic-inorganic hybrid system

    • Author(s)
      Huihui Wang, Mitsuru Izumi, Hideaki Endo, Hitoshi Ohnuki
    • Journal Title

      Transactions of the Materials Research Society of Japan (印刷中)

    • NAID

      130003398933

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Presentation] 交流インピーダンス法による超薄膜バイオセンサの開発2012

    • Author(s)
      大貫等、王慧慧、横山拓也、大野龍造、遠藤英明、和泉充
    • Organizer
      電気学会誘電絶縁研究会
    • Place of Presentation
      名古屋大学
    • Year and Date
      2012-01-20
    • Related Report
      2011 Annual Research Report
  • [Presentation] 金属的導電性LB膜を用いたソフトな電極形成技術の開発II2012

    • Author(s)
      望月健吾, 和泉充, 津谷大樹, 今久保達郎, 大貫等
    • Organizer
      第59回応用物理学関係連合講演会
    • Place of Presentation
      早稲田大学
    • Related Report
      2011 Annual Research Report
  • [Presentation] Label-free Impedance Biosensor of Avidin-Biotin Interaction Using Inter digitated Microelectrodes2011

    • Author(s)
      Huihui Wang, Takuya Yokoyama, Hitoshi Ohnuki, Hideaki Endo, Mitsuru Izumi
    • Organizer
      The 62^<nd> Annual Meeting of the International Society of Electrochemistry
    • Place of Presentation
      朱鷺メッセ(新潟)
    • Related Report
      2011 Annual Research Report
  • [Presentation] Study of the AC Impedance Measurements for Glucose Biosensor Based on 4-Mercaptobenzoic Acid2011

    • Author(s)
      H.Wang, T.Yokoyama, H.Ohnuki, H.Endo, M.Izumi
    • Organizer
      2nd International Conference on Bio-Sensing Technology
    • Place of Presentation
      アムステルダム(オランダ)
    • Related Report
      2011 Annual Research Report
  • [Presentation] アビジンービオチン反応の検出のためのインピーダンスセンサの作成2011

    • Author(s)
      横山拓也, 王慧慧, 遠藤英明, 和泉充, 大貫等
    • Organizer
      第72回応用物理学会学術講演会
    • Place of Presentation
      山形大学
    • Related Report
      2011 Annual Research Report
  • [Presentation] 有機-無機複合薄膜の交流インピーダンス法によるグルコースセンサの特性2011

    • Author(s)
      王慧慧, 大貫等,遠藤英明, 和泉充
    • Organizer
      第72回応用物理学会学術講演会
    • Place of Presentation
      山形大学
    • Related Report
      2011 Annual Research Report
  • [Presentation] Label-free Impedance Biosensor of Avidin-Biotin Interaction Using Inter digitaed Microelectrodes2011

    • Author(s)
      T.Yokoyama, H.Wang, H.Ohnuki, H.Endo, D.Tsuya, M.Izumi
    • Organizer
      第20回日本MRSシンポジウム
    • Place of Presentation
      横浜市開港記念館
    • Related Report
      2011 Annual Research Report
  • [Presentation] Fabrication and characterization of non-labeled IgA immunosensor2011

    • Author(s)
      R.Ohno, H.Ohnuki, H.Wang, T.Yokoyama, D.Tsuya, M.Izumi
    • Organizer
      第20回日本MRSシンポジウム
    • Place of Presentation
      横浜市開港記念館
    • Related Report
      2011 Annual Research Report
  • [Presentation] Fabrication of Tunneling Macro Junctions with Self-Assembled Monolayer and Langmuir-Blodgett Films2011

    • Author(s)
      K.Mochizuki, M.Izumi, T.Imakubo, D.Tsuya, H.Ohnuki
    • Organizer
      第20回日本MRSシンポジウム
    • Place of Presentation
      横浜市開港記念館
    • Related Report
      2011 Annual Research Report
  • [Presentation] 電気化学インピーダンス法を用いた非標識アフィニティーセンサの開発2011

    • Author(s)
      王慧慧, 横山拓也, 遠藤英明, 和泉充, 大貫等
    • Organizer
      第58回応用物理学関係連合講演会
    • Place of Presentation
      神奈川工科大学
    • Related Report
      2010 Annual Research Report
  • [Presentation] 有機-無機ハイブリッド界面を利用したアンペロメトリーバイオセンサの開発-2010

    • Author(s)
      王慧慧, 和泉充, 遠藤英明, 大貫, 等
    • Organizer
      第57回応用物理学関係連合講演会
    • Place of Presentation
      東海大学湘南キャンパス
    • Year and Date
      2010-03-17
    • Related Report
      2009 Annual Research Report
  • [Presentation] 金属的導電性LB膜を用いたソフトな電極形成技術の開発2010

    • Author(s)
      望月健吾, 和泉充, 池上敬一, 今久保達郎, 大貫, 等
    • Organizer
      第57回応用物理学関係連合講演会
    • Place of Presentation
      東海大学湘南キャンパス
    • Year and Date
      2010-03-17
    • Related Report
      2009 Annual Research Report
  • [Presentation] Fabrication, of soft electrode with metallic conducting Langmuir-Blodgett films2010

    • Author(s)
      Hitoshi Ohnuki, Kengo Mochizuki, Keiichi Ikegami, Tatsuro Imakubo, Mitsuru Izumi
    • Organizer
      13th International Conference on Organized Molecular Films
    • Place of Presentation
      Quebec(カナダ)
    • Related Report
      2010 Annual Research Report
  • [Presentation] Thin Film Biosensor Based on Organic-Inorganic Hybrid System2010

    • Author(s)
      Huihui Wang, Hitoshi Ohnuki, Hideaki Endo, Mitsuru Izumi
    • Organizer
      13th International Conference on Organized Molecular Films
    • Place of Presentation
      Quebec(カナダ)
    • Related Report
      2010 Annual Research Report
  • [Presentation] Thin Film Biosensor Based on Organic-Inorganic Hybrid System2010

    • Author(s)
      Huihui Wang, Mitsuru Izumi, Hideaki Endo, Hitoshi Ohnuki
    • Organizer
      61st Annual Meeting of the International Society of Electrochemistry
    • Place of Presentation
      Nice(フランス)
    • Related Report
      2010 Annual Research Report
  • [Presentation] Preparation of Amperometric Glucose Biosensor Based on 4-Mercaptobezoic Acid Self-Assembled on Gold2010

    • Author(s)
      Huihui Wang, Mitsuru Izumi, Hideaki Endo, Hitoshi Ohnuki
    • Organizer
      The 9th International Conference on Nano-Molecular Electronics
    • Place of Presentation
      神戸コンベンションセンター
    • Related Report
      2010 Annual Research Report
  • [Presentation] Observation of Tunneling Currents through Self-Assembled Monolayer Using MIM Junction Fabricated from Conducting LB Films2010

    • Author(s)
      Kengo Mochizuki, Hitoshi Ohnuki, Mitsuru Izumi, Keiichi Ikegami, Tatsuro Imakubo
    • Organizer
      The 9th International Conference on Nano-Molecular Electronics
    • Place of Presentation
      Kobe(日本)
    • Related Report
      2010 Annual Research Report
  • [Presentation] Thin Film Biosensor Based on Organic-Inorganic Hybrid System2010

    • Author(s)
      Huihui Wang, Hitoshi Ohnuki, Hideaki Endo, Mitsuru Izumi
    • Organizer
      第19回日本MRSシンポジウム
    • Place of Presentation
      横浜市開港記念館
    • Related Report
      2010 Annual Research Report
  • [Presentation] Preparation of amperometric biosensor based on organic-inorganic hybrid system2009

    • Author(s)
      Huihui Wang, Mitsuru Izumi, Hideaki Endo, Hitoshi Ohnuki
    • Organizer
      第19回日本MRS学術シンポジウム
    • Place of Presentation
      横浜市開港記念館
    • Year and Date
      2009-12-08
    • Related Report
      2009 Annual Research Report
  • [Presentation] Fabrication of soft electrode with metallic conducting Langmuir-Blodgett films2009

    • Author(s)
      Hitoshi Ohnuki, Kengo Mochizuki, Keiichi Ikegami, Tatsuro Imakubo, and Mitsure Izumi
    • Organizer
      13th International Conference on Organized Molecular Films
    • Place of Presentation
      Tours(フランス)
    • Related Report
      2011 Final Research Report
  • [Remarks]

    • URL

      http://pubdb.kaiyodai.ac.jp/make_personal.php?bango=40344036&mode=syokusyu&code_page=

    • Related Report
      2009 Annual Research Report
  • [Patent(Industrial Property Rights)] ラングミュア・ブロジェット絶縁薄膜およびその作成方法2010

    • Inventor(s)
      池上敬一、杉本崇、蛯名武雄、星靖、大貫等、望月健吾
    • Industrial Property Rights Holder
      産業技術総合研究所,東京海洋大学
    • Filing Date
      2010-03-04
    • Related Report
      2011 Final Research Report
  • [Patent(Industrial Property Rights)] ラングミュア・ブロジェット絶縁薄膜およびその作成方法2010

    • Inventor(s)
      大貫等, 望月健吾, 池上敬一, 杉本崇, 蛯名武雄, 星靖
    • Industrial Property Rights Holder
      東京海洋大学、産業技術総合研究所
    • Industrial Property Number
      2010-047499
    • Filing Date
      2010-03-04
    • Related Report
      2009 Annual Research Report

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Published: 2009-04-01   Modified: 2016-04-21  

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