Development of Coherent Raman Spectroscopy for Biological Molecules in Terahertz Frequency Region
| Project/Area Number |
21360031
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Applied optics/Quantum optical engineering
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| Research Institution | University of Fukui |
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Principal Investigator |
TANI Masahiko 福井大学, 遠赤外領域開発研究センター, 教授 (00346181)
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| Co-Investigator(Kenkyū-buntansha) |
YAMAGUCHI Mariko 奈良先端科学技術大学院大学, 物質創成科学研究科, 助教 (50521738)
YAMAMOTO Kohji 福井大学, 遠赤外領域開発研究センター, 准教授 (70432507)
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| Co-Investigator(Renkei-kenkyūsha) |
HANGYO Masanori 大阪大学, レーザーエネルギー学研究センター, 教授 (10144429)
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥18,980,000 (Direct Cost: ¥14,600,000、Indirect Cost: ¥4,380,000)
Fiscal Year 2011: ¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2010: ¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2009: ¥11,050,000 (Direct Cost: ¥8,500,000、Indirect Cost: ¥2,550,000)
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| Keywords | 光計測 / テラヘルツ分光 / テラヘルツ / コヒーレントラマン / 生体分子 / 顕微イメージング |
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| Research Abstract |
Anharmonic and large-amplitude vibrational modes in biological macro-molecules are thought to be important for their functions and interaction with other molecules, governing the thermo-dynamical the properties. To observe such molecular vibrations in terahertz(THz) frequency region, a novel coherent Raman technique(THz Time-Domain Coherent Raman Spectroscopy), which utilizes THz optical beats created by two frequency-chirped femtosecond pulses and detects the coherent Raman signal in time-domain, has been developed and applied to some non-organic samples for demonstration.
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Report
(4 results)
Research Products
(47 results)
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[Journal Article] Terahertz emission from Indium Oxide films grown on MgO substrates using sub-bandgap photon energy excitation2012
Author(s)
Elmer S.Estacio, Christopher T.Que, Fritz C.B.Awitan, Jan Issac Bugante, Francesca Isabel de Vera, Jonathan Azares, Jessica Afalla, Jeffrey de Vero, Armando S.Somintac, Roland V.Sarmago, Arnel A.Salvador, Kohji Yamamoto, Masahiko Tani
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Journal Title
Optics Express
Volume: 20
Pages: 4518-4524
Related Report
Peer Reviewed
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[Presentation] Development of Emitters and Detectors for THz Time-Domain Spectroscopy System with a 1.55μm fs Fiber Laser2011
Author(s)
M.Tani, H.Nakajima, K.Horita, T.Kinoshita, T.Nagase, M.Hibi, K.Saito, C.T.Que, E.Estacio, K.Yamamoto, F.Miyamaru, S.Nishizawa
Organizer
International Photonics Conference 2011 (IPC2011)
Place of Presentation
Tainan, Taiwan(Invited)
Year and Date
2011-12-09
Related Report
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[Presentation] Efficient THz emitters and detectors for 1.55-μm fs laser excitation2011
Author(s)
M.Tani, H.Nakajima, K.Horita, T.Kinoshita, T.Nagase, M.Hibi, K.Saito, C.T.Que, E.Estacio, K.Yamamoto, F.Miyamaru, S.Nishizawa
Organizer
The International Photonics and OptoElectronics Meetings (POEM) 2011
Place of Presentation
Wuhan, China(Invited)
Year and Date
2011-11-03
Related Report
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[Presentation] Recognition of Sound-alike Medicine and Dynamics Study of Saturated Hydrocarbon by Terahertz-Time-Domain Spectroscopy (Invited)2011
Author(s)
Kohji Yamamoto, Keita Takagi, Ryouhei Yasuda, Hirokatsu Itoh, Itaru Torii, Kazutoshi Fukui, Masahiko Tani, Seizi Nishizawa, Masava Kawase
Organizer
The 2nd THz-Bio International Workshop
Place of Presentation
Center for THz-Bio Applic ation Systems, Seoul National University, Korea
Year and Date
2011-01-19
Related Report
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