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Explanation of antifreeze activity of antifreeze proteins and antifreeze synthetic polymers

Research Project

Project/Area Number 21360102
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Thermal engineering
Research InstitutionNational Institute of Advanced Industrial Science and Technology

Principal Investigator

INADA Takaaki  独立行政法人産業技術総合研究所, エネルギー技術研究部門, 主任研究員 (60356491)

Co-Investigator(Kenkyū-buntansha) HIRANO Satoshi  独立行政法人産業技術総合研究所, エネルギー技術研究部門, 研究グループ長 (60357861)
Co-Investigator(Renkei-kenkyūsha) FUNAKOSHI Kunio  鈴鹿工業高等専門学校, 生物応用化学科, 講師 (00533457)
SETO Takafumi  金沢大学, 自然システム学系, 准教授 (40344155)
Project Period (FY) 2009 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥19,240,000 (Direct Cost: ¥14,800,000、Indirect Cost: ¥4,440,000)
Fiscal Year 2011: ¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2010: ¥7,410,000 (Direct Cost: ¥5,700,000、Indirect Cost: ¥1,710,000)
Fiscal Year 2009: ¥7,150,000 (Direct Cost: ¥5,500,000、Indirect Cost: ¥1,650,000)
Keywords氷 / 核生成 / 結晶成長 / 不凍タンパク質 / 合成高分子 / 生体機能利用 / 融解 / 高分子
Research Abstract

Inhibition of ice nucleation by antifreeze proteins(AFPs) and antifreeze synthetic polymers(AFSPs) was experimentally investigated by using silver iodide particles as ice nuclei. The results showed that AFP and AFSP molecules inhibit ice nucleation not by directly affecting ice-like water clusters, but by masking ice nucleating sites on silver iodide surfaces. A few synthetic polymers, previously not considered as AFSPs, were also found to inactivate the ice nucleating activity of silver iodide.

Report

(4 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • 2009 Annual Research Report
  • Research Products

    (19 results)

All 2012 2011 2010 2009 Other

All Journal Article (6 results) (of which Peer Reviewed: 4 results) Presentation (11 results) Remarks (2 results)

  • [Journal Article] Inactivation of ice nucleating activity of silver iodide by antifreeze proteins and synthetic polymers2012

    • Author(s)
      稲田孝明、小山寿恵、後藤文俊、瀬戸章文
    • Journal Title

      Journal of Physical Chemistry B

      Volume: Vol.116、No.18 Issue: 18 Pages: 5364-5371

    • DOI

      10.1021/jp300535z

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Freezing activities of flavonoids in solutions containing different ice nucleators2012

    • Author(s)
      桑原慎子、春日純、Donghui Wang、福士幸治、荒川圭太、小山寿恵、稲田孝明、藤川清三
    • Journal Title

      Cryobiology

      Volume: Vol.64、No.3 Issue: 3 Pages: 279-285

    • DOI

      10.1016/j.cryobiol.2012.02.012

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] 不凍タンパク質による氷の核生成制御2011

    • Author(s)
      稲田孝明、小山寿恵
    • Journal Title

      冷凍

      Volume: 86巻、1005号 Pages: 569-575

    • Related Report
      2011 Final Research Report
  • [Journal Article] Change of supercooling capability in solutions containing different kinds of ice nucleators by flavonol glycosides from deep supercooling xylem parenchyma cells in trees2011

    • Author(s)
      桑原慎子、春日純、Donghui Wang、福士幸治、荒川圭太、小山寿恵、稲田孝明、藤川清三
    • Journal Title

      Cryobiology

      Volume: Vol.63、No.3 Issue: 3 Pages: 157-163

    • DOI

      10.1016/j.cryobiol.2011.06.001

    • NAID

      120003678802

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Ice nucleation in emulsified solutions of antifreeze protein type III and poly(vinyl alcohol)2011

    • Author(s)
      稲田孝明、小山寿恵、後藤文俊、瀬戸章文
    • Journal Title

      Journal of Physical Chemistry B

      Volume: Vol.115、No.24 Issue: 24 Pages: 7914-7922

    • DOI

      10.1021/jp111745v

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] 不凍タンパク質による氷の核生成抑制2011

    • Author(s)
      稲田孝明
    • Journal Title

      冷凍

      Volume: 86巻 Pages: 569-575

    • NAID

      10029433365

    • Related Report
      2011 Annual Research Report 2010 Annual Research Report
  • [Presentation] 不凍タンパク質の機能とその応用(基調講演)2011

    • Author(s)
      稲田孝明
    • Organizer
      2011年度日本冷凍空調学会年次大会
    • Place of Presentation
      東京大学(東京都)
    • Year and Date
      2011-09-14
    • Related Report
      2011 Final Research Report
  • [Presentation] 氷の核生成に対する不凍タンパク質の効果についての考察2011

    • Author(s)
      稲田孝明、小山寿恵、上平未枝、後藤文俊、瀬戸章文
    • Organizer
      2011年度日本冷凍空調学会年次大会
    • Place of Presentation
      東京大学(東京都)
    • Year and Date
      2011-09-14
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] 不凍タンパク質の機能とその応用2011

    • Author(s)
      稲田孝明
    • Organizer
      2011年度日本冷凍空調学会年次大会
    • Place of Presentation
      東京大学(東京都)(基調講演)
    • Year and Date
      2011-09-14
    • Related Report
      2011 Annual Research Report
  • [Presentation] Applications of antifreeze proteins and antifreeze synthetic polymers in ice slurry systems2011

    • Author(s)
      稲田孝明
    • Organizer
      1st International Ice-Binding Protein Conference
    • Place of Presentation
      Queen's University(カナダ)
    • Year and Date
      2011-08-06
    • Related Report
      2011 Final Research Report
  • [Presentation] Applications of antifreeze proteins and antifreeze synthetic polymers in ice slurry systems2011

    • Author(s)
      稲田孝明
    • Organizer
      1st International Ice-Binding Protein Conference
    • Place of Presentation
      Queen's University(カナダ)(依頼講演)
    • Year and Date
      2011-08-06
    • Related Report
      2011 Annual Research Report
  • [Presentation] よう化銀の氷核活性に対する高分子の影響2011

    • Author(s)
      稲田孝明、小山寿恵、後藤文俊、瀬戸章文
    • Organizer
      第48回日本伝熱シンポジウム
    • Place of Presentation
      岡山コンベンションセンター(岡山県)
    • Year and Date
      2011-06-02
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] W/Oエマルションを用いた氷の核生成に及ぼす添加物の影響2010

    • Author(s)
      後藤文俊、瀬戸章文、大谷吉生、小山寿恵、稲田孝明
    • Organizer
      化学工学会第42回秋季大会
    • Place of Presentation
      同志社大学(京都府)
    • Year and Date
      2010-09-06
    • Related Report
      2011 Final Research Report
  • [Presentation] W/Oエマルションを用いた氷の核生成に及ぼす添加物の影響評価2010

    • Author(s)
      後藤文俊
    • Organizer
      化学工学第42回秋季大会
    • Place of Presentation
      同志社大学(京都市)
    • Year and Date
      2010-09-06
    • Related Report
      2010 Annual Research Report
  • [Presentation] 不凍タンパク質水溶液中の氷の均質核生成2010

    • Author(s)
      稲田孝明、小山寿恵、後藤文俊、瀬戸章文
    • Organizer
      第47回日本伝熱シンポジウム
    • Place of Presentation
      札幌コンベンションセンター(北海道)
    • Year and Date
      2010-05-28
    • Related Report
      2011 Final Research Report
  • [Presentation] 不凍タンパク質水溶液中の氷の均質核生成2010

    • Author(s)
      稲田孝明
    • Organizer
      第47回日本伝熱シンポジウム
    • Place of Presentation
      札幌コンベンションセンター(札幌市)
    • Year and Date
      2010-05-28
    • Related Report
      2010 Annual Research Report
  • [Presentation] 熱交換器における水の過冷却維持に対する添加物の影響2009

    • Author(s)
      稲田孝明、船越邦夫
    • Organizer
      2009年度日本冷凍空調学会年次大会
    • Place of Presentation
      中央大学駿河台記念館(東京都)
    • Year and Date
      2009-10-21
    • Related Report
      2011 Final Research Report 2009 Annual Research Report
  • [Remarks]

    • URL

      http://staff.aist.go.jp/t-inada/index_jp.htm

    • Related Report
      2011 Final Research Report
  • [Remarks]

    • URL

      http://staff.aist.go.jp/t-inada/index_jp.htm

    • Related Report
      2011 Annual Research Report

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Published: 2009-04-01   Modified: 2016-04-21  

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