Target self-search type micro-bubble manipulation by an ultrasonic wave
| Project/Area Number |
21360195
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Measurement engineering
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| Research Institution | Gunma University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
MIWA Takashi 群馬大学, 大学院・工学研究科, 教授 (30313414)
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥17,810,000 (Direct Cost: ¥13,700,000、Indirect Cost: ¥4,110,000)
Fiscal Year 2011: ¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2010: ¥6,500,000 (Direct Cost: ¥5,000,000、Indirect Cost: ¥1,500,000)
Fiscal Year 2009: ¥7,280,000 (Direct Cost: ¥5,600,000、Indirect Cost: ¥1,680,000)
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| Keywords | 超音波 / 微小気泡 / 音響放射圧 / ドラッグデリバリシステム / ターゲッティング / トラッピング / Bjerknes力 / 気泡間相互作用 / 気泡クラウド / キャビテーション / ソノポレーション / 気泡トラッピング / 共焦点レーザー顕微鏡 / 気泡破壊 / 気泡 / アンジュレーション / Bierknes Force / 2次超音波 |
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| Research Abstract |
Micro-bubble receives two kinds of acoustic radiation forces from ultrasonic wave. If the acoustic radiation forces are used, movement of micro-bubble is controllable from the outside. In this research, micro-bubble trapping methods to the target are newly developed aiming at improvement of drug injection efficiency of drug delivery system. One is the self-trapping method and another is the frequency operating method. Experiments are carried using an ultrasonic contrast agent. Usefulness and the effect of ultrasonic wave irradiation sequence are shown.
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Report
(4 results)
Research Products
(39 results)
