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Establishment of Preparation Method for Magnetic Materials Having High Heat Generation Ability and its Biocompatibility

Research Project

Project/Area Number 21360341
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Structural/Functional materials
Research InstitutionEhime University

Principal Investigator

AONO Hiromichi  愛媛大学, 大学院・理工学研究科, 准教授 (00184052)

Project Period (FY) 2009 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥18,330,000 (Direct Cost: ¥14,100,000、Indirect Cost: ¥4,230,000)
Fiscal Year 2011: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Fiscal Year 2010: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Fiscal Year 2009: ¥13,260,000 (Direct Cost: ¥10,200,000、Indirect Cost: ¥3,060,000)
Keywords癌治療 / 交流磁場 / 発熱 / 磁性材料 / フェライト / 焼灼療法 / Y_3Fe_5O_<12> / ビーズミル粉砕 / 逆共沈法 / 発熱特性 / ヒステリシス損失 / 微粒子 / DDS
Research Abstract

Magnetic materials having a high heat generation ability in an AC magnetic field have been studied for use in new thermal coagulation therapy for the local treatment of cancerous tissues. We mainly studied(1) Heat generation ability and heat generation mechanism for the ferrite materials obtained using physical beads milling,(2) Heat generation ability and heat generation mechanism for new Y_3Fe_5O_<12>-based material having high heat generation ability, and(3) Preparation of microsphere materials using spray dryer for embolization therapy application.

Report

(4 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • 2009 Annual Research Report
  • Research Products

    (37 results)

All 2012 2011 2010 2009 Other

All Journal Article (9 results) (of which Peer Reviewed: 8 results) Presentation (23 results) Remarks (1 results) Patent(Industrial Property Rights) (4 results)

  • [Journal Article] High Heat Generation Ability in AC Magnetic Field for Nano-sized Magnetic Y_3Fe_5O_<12> Powder Prepared by Bead Milling2012

    • Author(s)
      H. Aono, H. Ebara, R. Senba, T. Naohara, T. Maehara, H. Hirazawa, and Y. Watanabe
    • Journal Title

      J. Magn. Magn. Mater.

      Volume: Vol.324, No.12 Pages: 1985-1991

    • Related Report
      2011 Final Research Report
  • [Journal Article] Tumor local chemohyperthermia using docetaxel-embedded magnetoliposomes : Interaction of chemotherapy and hyperthermia2012

    • Author(s)
      M.Yoshida, M.Sato, Y.Yamamoto, T.Maehara, T.Naohara, H.Aono, H.Sugishita, K.Sato, Y.Watanabe
    • Journal Title

      Journal of Gastroenterology and Hepatology

      Volume: 27 Issue: 2 Pages: 406-411

    • DOI

      10.1111/j.1440-1746.2011.06972.x

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] High heat generation ability in AC magnetic field for Y_3Fe_5O_<12> powder prepared using bead milling2011

    • Author(s)
      H. Aono, H. Ebara, R. Senba, T. Naohara, T. Maehara, H. Hirazawa, and Y. Watanabe
    • Journal Title

      J. Am. Ceram. Soc.

      Volume: Vol.94, No.12 Pages: 4116-4119

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Synthesis and hyperthermia property of hydroxyapatite-ferrite hybridparticles by ultrasonic spray pyrolysis2011

    • Author(s)
      N.Wakiya, A.Inukai, N.Sakamoto, H.Aono, O.Sakurai, K.Shnozaki
    • Journal Title

      J.Magn.Magn.Mater.

      Volume: 323 Issue: 7 Pages: 965-969

    • DOI

      10.1016/j.jmmm.2010.11.080

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] New Heat Generation Material in AC Magnetic Field For Y_3Fe_5O_<12>-based Powder Material Synthesized by Reverse Coprecipication Method2011

    • Author(s)
      H.Aono, K.Moritani, T.Naohara, T.Maehara, H.Hirazawa, Y.Watanabe
    • Journal Title

      Materials Letters

      Volume: 65 Issue: 10 Pages: 1454-1456

    • DOI

      10.1016/j.matlet.2011.02.034

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effect of bead milling on heat generation ability in AC magnetic field of FeFe_2O_4 powder2011

    • Author(s)
      H.Aono, Y.Watanabe, T.Naohara, T.Maehara, H.Hirazawa, Y.Watanabe
    • Journal Title

      Materials Chemistry and Physics

      Volume: 129 Issue: 3 Pages: 1081-1088

    • DOI

      10.1016/j.matchemphys.2011.05.061

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] High heat generation ability in AC magnetic field for Y_3Fe_5O_<12> powder prepared using bead milling2011

    • Author(s)
      H.Aono, H.Ebara, R.Senba, T.Naohara, T.Maehara, H.Hirazawa, Y.Watanabe
    • Journal Title

      J.Am.Ceram.Soc.

      Volume: 94 Issue: 12 Pages: 4116-4119

    • DOI

      10.1111/j.1551-2916.2011.04879.x

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Heat generation ability under AC magnetic field of nano MgFe_2O_4-based ferrite powder prepared by bead milling2011

    • Author(s)
      H.Hirazawa, H.Aono, T.Naohara, T.Maehara, M.Sato, Y.Watanabe
    • Journal Title

      J.Magn.Magn.Mater.

      Volume: 323(6) Pages: 675-680

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Preparation of MgFe_2O_4 Microsphere Using Spray Dryer for Application of Embolization Therapy2010

    • Author(s)
      H.Aono, T.Naohara, T.Maehara, H.Hirazawa, Y.Watanabe
    • Journal Title

      J.Ceram.Soc.Jpn.

      Volume: 118(12) Pages: 1207-1211

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Presentation] イットリウム鉄ガーネット系粉末の逆共沈法による合成と交流磁場中における発熱機構2012

    • Author(s)
      西森, 青野, 猶原, 前原, 渡部, 平澤
    • Organizer
      日本セラミックス協会年会
    • Place of Presentation
      京都大学
    • Year and Date
      2012-03-21
    • Related Report
      2011 Annual Research Report
  • [Presentation] 希土類鉄ガーネット系R_3Fe_5O_<12>(R=Y,Sm,Gd,Dy,Ho,Er)粉末の交流磁場中における発熱特性2012

    • Author(s)
      田村, 青野, 猶原, 前原, 渡部, 平澤
    • Organizer
      日本セラミックス協会年会
    • Place of Presentation
      京都大学
    • Year and Date
      2012-03-19
    • Related Report
      2011 Annual Research Report
  • [Presentation] ビーズミル粉砕により得たY_3Fe_5O_<12>フェライト微粒子の粒子成長による発熱機構への影響2012

    • Author(s)
      秋山, 青野, 猶原, 前原, 渡部, 平澤
    • Organizer
      日本セラミックス協会年会
    • Place of Presentation
      京都大学
    • Year and Date
      2012-03-19
    • Related Report
      2011 Annual Research Report
  • [Presentation] イットリウム鉄ガーネット粉末の逆共沈法による合成と交流磁場中における発熱機構2012

    • Author(s)
      西森忠彦ら
    • Organizer
      日本セラミックス協会年会
    • Place of Presentation
      京都
    • Related Report
      2011 Final Research Report
  • [Presentation] 逆共沈法によるY_3Fe_5O_<12>フェライト磁性体粉末の合成と交流磁場中における発熱機構2011

    • Author(s)
      西森, 青野, 猶原, 前原, 渡部, 平澤
    • Organizer
      日本セラミックス協会秋季シンポジウム
    • Place of Presentation
      北海道大学
    • Year and Date
      2011-09-07
    • Related Report
      2011 Annual Research Report
  • [Presentation] ガーネット系Y_3Fe_5O_<12>フェライトのビーズミル粉砕による微粒子化とマイクロ球体の作製2011

    • Author(s)
      仙波, 青野, 猶原, 前原, 渡部, 平澤
    • Organizer
      日本セラミックス協会秋季シンポジウム
    • Place of Presentation
      北海道大学
    • Year and Date
      2011-09-07
    • Related Report
      2011 Annual Research Report
  • [Presentation] 化学的合成および物理的粉砕により作製したマグネタイト超常磁性微粒子の交流磁場中における発熱機構2011

    • Author(s)
      渡部, 青野, 猶原, 前原, 渡部, 平澤
    • Organizer
      日本セラミックス協会秋季シンポジウム
    • Place of Presentation
      北海道大学
    • Year and Date
      2011-09-07
    • Related Report
      2011 Annual Research Report
  • [Presentation] ガーネット系Y_3Fe_5O_12 フェライトのビーズミル粉砕による微粒子化と交流磁場中での発熱特性2011

    • Author(s)
      江原弘規・青野宏通・猶原隆・前原常弘・渡部祐司・平澤英之
    • Organizer
      日本セラミックス協会春季大会
    • Place of Presentation
      静岡大学
    • Related Report
      2010 Annual Research Report
  • [Presentation] ビーズミル粉砕により得られたナノ微粒子の交流磁場中における発熱機構2011

    • Author(s)
      渡部祐輔・青野宏通・猶原隆・前原常弘・渡部祐司・平澤英之
    • Organizer
      日本セラミックス協会春季大会
    • Place of Presentation
      静岡大学
    • Related Report
      2010 Annual Research Report
  • [Presentation] 塞栓療法への応用を目的としたスプレードライ法によるY_3Fe_5O_<12>フェライトマイクロ球体の作製2011

    • Author(s)
      仙波亮太・青野宏通・猶原隆・前原常弘・渡部祐司・平澤英之
    • Organizer
      日本セラミックス協会春季大会
    • Place of Presentation
      静岡大学
    • Related Report
      2010 Annual Research Report
  • [Presentation] 逆共沈法により得られたY_3Fe_5O_<12>系フェライト粉末の交流磁場中における発熱特性2011

    • Author(s)
      西森忠彦・青野宏通・猶原隆・前原常弘・渡部祐司・平澤英之
    • Organizer
      日本セラミックス協会春季大会
    • Place of Presentation
      静岡大学
    • Related Report
      2010 Annual Research Report
  • [Presentation] ガーネット系Y_3Fe_5O_<12>フェライトのビーズミル粉砕による微粒子化と交流磁場中での発熱特牲2010

    • Author(s)
      江原弘規・青野宏通・猶原隆・前原常弘・渡部祐司・平澤英之
    • Organizer
      第17回ヤングセラミストミーティングin中四国
    • Place of Presentation
      愛媛大学
    • Year and Date
      2010-11-27
    • Related Report
      2010 Annual Research Report
  • [Presentation] Y_3Fe_5O_<12>を基本とするフェライトの交流磁場中での発熱特性2010

    • Author(s)
      青野宏通, 平澤英之・猶原隆・前原常弘・渡部祐司・
    • Organizer
      日本希土類学会
    • Place of Presentation
      北九州国際会議場
    • Related Report
      2010 Annual Research Report
  • [Presentation] Heat Generation Ability in AC Magnetic Field for Y_3Fe_5O_<12>-based Garnet Ferrite2010

    • Author(s)
      H.Hirazawa, H.Aono, T.Naohara, T.Maehara, M.Sato, Y.Watanabe
    • Organizer
      3^<th> International Congress on Ceramics
    • Place of Presentation
      グランキューブ大阪
    • Related Report
      2010 Annual Research Report
  • [Presentation] ガーネット系Y_3Fe_5O_<12>を基本とするフェライトの交流磁場中での発熱特性2010

    • Author(s)
      森谷健史・青野宏通・猶原隆・前原常弘・渡部祐司・平澤英之
    • Organizer
      日本セラミックス協会年会
    • Place of Presentation
      東京農工大学
    • Related Report
      2009 Annual Research Report
  • [Presentation] 癌治療への応用を目的としたガーネット系Y_3Fe_5O_<12>フェライトのビーズミル粉砕による微粒子化と交流磁場中での発熱特性2010

    • Author(s)
      江原弘規・青野宏通・猶原隆・前原常弘・渡部祐司・平澤英之
    • Organizer
      日本セラミックス協会年会
    • Place of Presentation
      東京農工大学
    • Related Report
      2009 Annual Research Report
  • [Presentation] 様々な化学的作製法により作製したMg_<1-x>Ca_xFe_2O_4系フェライトの交流磁場中で発熱特性2009

    • Author(s)
      米田渓一・青野宏通・猶原隆・前原常弘・渡部祐司・平澤英之
    • Organizer
      日本セラミックス協会秋季シンポジウム
    • Place of Presentation
      愛媛大学
    • Related Report
      2009 Annual Research Report
  • [Presentation] ガーネット系Y_<3-x>Gd_xFe_5O_<12>系フェライトの交流磁場中での発熱特性2009

    • Author(s)
      森谷健史・青野宏通・猶原隆・前原常弘・渡部祐司・平澤英之
    • Organizer
      日本セラミックス協会秋季シンポジウム
    • Place of Presentation
      愛媛大学
    • Related Report
      2009 Annual Research Report
  • [Presentation] 物理的手法によるマグネタイトの粒子径制御と交流磁場中での発熱特性2009

    • Author(s)
      平澤英之・佐々木裕臣・青野宏通・猶原隆・前原常弘・渡部祐司・佐藤充則
    • Organizer
      日本セラミックス協会秋季シンポジウム
    • Place of Presentation
      愛媛大学
    • Related Report
      2009 Annual Research Report
  • [Presentation] High Heat Generation Ability under AC Magnetic Field for Y_3Fe_5O_<12> Prepeared by Reverse Coprecipitation Method2009

    • Author(s)
      青野宏通, 平澤英之, 猶原隆・前原常弘・渡部祐司
    • Organizer
      6^<th> International Conference on Electromagnetic Processing of Materials(EPM)
    • Place of Presentation
      Dresden, Germany
    • Related Report
      2009 Annual Research Report
  • [Presentation] Preparation of Fine Ferrite Powder using Bead Mill and its Heat Generation Ability in AC Magnetic Field2009

    • Author(s)
      平澤英之, 青野宏通, 猶原隆・前原常弘, 佐藤充則, 渡部祐司
    • Organizer
      6^<th> International Conference on Electromagnetic Processing of Materials(EPM)
    • Place of Presentation
      Dresden, Germany
    • Related Report
      2009 Annual Research Report
  • [Presentation] 癌の交流磁場焼灼療法への応用を目的としたフェライト材料の設計2009

    • Author(s)
      青野宏通・猶原隆・前原常弘・渡部祐司・平澤英之
    • Organizer
      西日本化学会
    • Place of Presentation
      愛媛大学
    • Related Report
      2009 Annual Research Report
  • [Presentation] Effect of Cystal Sizes on Heat Generation Ability in AC Magnetic Field for FeFe_2O_4 Ferrite Powder Prepared by Bead Milling2009

    • Author(s)
      平澤英之, 青野宏通, 猶原隆・前原常弘, 佐藤充則, 渡部祐司
    • Organizer
      第26回日韓セラミックスセミナー
    • Place of Presentation
      つくば
    • Related Report
      2009 Annual Research Report
  • [Remarks]

    • URL

      http://www.energy-materials.jp/research_01.html

    • Related Report
      2011 Annual Research Report
  • [Patent(Industrial Property Rights)] Y_<3-X> Ln_XFe_5O_<12>粉末材料及びその製造方法2009

    • Inventor(s)
      青野宏通、猶原隆、前原常弘
    • Industrial Property Rights Holder
      国立大学法人愛媛大学
    • Filing Date
      2009-09-15
    • Related Report
      2011 Final Research Report
  • [Patent(Industrial Property Rights)] FeFe_2O_4粉末材料及びその製造方法2009

    • Inventor(s)
      青野宏通、猶原隆、前原常弘
    • Industrial Property Rights Holder
      青野宏通、猶原隆、前原常弘
    • Filing Date
      2009-09-15
    • Related Report
      2011 Final Research Report
  • [Patent(Industrial Property Rights)] Y_<3-X>LnxFe_5O_<12>粉末材料及びその製造方法2009

    • Inventor(s)
      青野宏通, 猶原隆, 前原常弘
    • Industrial Property Rights Holder
      国立大学法人愛媛大学
    • Industrial Property Number
      2009-213500
    • Filing Date
      2009-09-15
    • Related Report
      2009 Annual Research Report
  • [Patent(Industrial Property Rights)] FeFe_2O_4粉末材料及びその製造方法2009

    • Inventor(s)
      青野宏通, 猶原隆, 前原常弘
    • Industrial Property Rights Holder
      青野宏通, 猶原隆, 前原常弘
    • Filing Date
      2009-09-15
    • Related Report
      2009 Annual Research Report

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Published: 2009-04-01   Modified: 2016-04-21  

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