| Budget Amount *help |
¥18,590,000 (Direct Cost: ¥14,300,000、Indirect Cost: ¥4,290,000)
Fiscal Year 2011: ¥5,980,000 (Direct Cost: ¥4,600,000、Indirect Cost: ¥1,380,000)
Fiscal Year 2010: ¥5,980,000 (Direct Cost: ¥4,600,000、Indirect Cost: ¥1,380,000)
Fiscal Year 2009: ¥6,630,000 (Direct Cost: ¥5,100,000、Indirect Cost: ¥1,530,000)
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| Research Abstract |
In this study, we have been trying to clarify the mechanisms regulating developmental fate and sex differences of the germ cells in Drosophila. What has remained a fascinating puzzle is how the germ cell decides its own sex. Here, we show that a single gene(Sxl) can initiate female sexual development in the primordial germ cells(PGCs). Our findings pave the way for future work that will help to establish the extent to which sex detemination mechanism is conserved in germ cell.
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