Study on sperm motility and fertility
| Project/Area Number |
21370030
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Animal physiology/Animal behavior
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| Research Institution | The University of Tokyo |
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Principal Investigator |
YOSHIDA Manabu 東京大学, 大学院・理学系研究科, 准教授 (60301785)
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| Co-Investigator(Kenkyū-buntansha) |
YOSHIDA Kaoru 桐蔭横浜大学, 先端医用工学センター, 講師 (70398973)
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥18,980,000 (Direct Cost: ¥14,600,000、Indirect Cost: ¥4,380,000)
Fiscal Year 2011: ¥6,240,000 (Direct Cost: ¥4,800,000、Indirect Cost: ¥1,440,000)
Fiscal Year 2010: ¥6,240,000 (Direct Cost: ¥4,800,000、Indirect Cost: ¥1,440,000)
Fiscal Year 2009: ¥6,500,000 (Direct Cost: ¥5,000,000、Indirect Cost: ¥1,500,000)
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| Keywords | 受精 / 精子活性化・誘引物質 / 精子受精能阻害物質 / 精子走化性 / 受精能獲得 / カタユウレイボヤ / マウス / 精子 / 先体反応 / 動物生理化学 / ホヤ |
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| Research Abstract |
We are aiming to elucidate of control mechanisms of sperm movement and function during fertilization. In this study, we have studied on chemotaxis of ascidian spermatozoa and regulation of sperm capacitation by seminal plasma. Finally, we have found that a plasma membrane Ca^<2+>/ATPase is involved in ascidian sperm chemotaxis. In mouse, seminal vesicle secretion 2(SVS2) is essential for regulating sperm capacitation in female genital tract.
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Report
(4 results)
Research Products
(94 results)
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[Journal Article]2010
Author(s)
Yoshida, K
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Journal Title
Human Spermatozoa : Maturation, Capacitation and Abnormalities.(Nova Science Publishers, Inc.)
Pages: 205-220
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[Presentation] The essential role of seminal vesicle secretions on the sperm fertility in the female reproductive tract2010
Author(s)
Kawano, N., Araki, N., Yoshida, K., Yoshida, M., and Miyado, K.
Organizer
11th International Symposium on Spermatology
Place of Presentation
Okinawa, Japan
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[Presentation] How does the ascidian egg attract sperm? Releasing mechanisms of the sperm attractant SAAF from the egg2009
Author(s)
Kondoh, E., Konno, A., Inaba, K., Ohishi, T., Murata, M., and Yoshida, M.
Organizer
5th International Tunicate Meeting
Place of Presentation
Okinawa, Japan
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[Presentation] When do spermatozoa detect the chemoattractant?-Experimental and simulation study2009
Author(s)
Shiba, K., Miyashiro, D., Kamimura, S., Baba, S. A, and Yoshida, M.
Organizer
Gordon Research Conference : Fertilization and the Activation of Development
Place of Presentation
Plymouth, NH, USA
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