Study on sperm motility and fertility

• Project/Area Number: 21370030
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Animal physiology/Animal behavior
• Research Institution: The University of Tokyo
• Principal Investigator: YOSHIDA Manabu 東京大学, 大学院・理学系研究科, 准教授 (60301785)
• Co-Investigator(Kenkyū-buntansha): YOSHIDA Kaoru 桐蔭横浜大学, 先端医用工学センター, 講師 (70398973)
• Project Period (FY): 2009 – 2011
• Project Status: Completed (Fiscal Year 2011)
• Budget Amount: ¥18,980,000 (Direct Cost: ¥14,600,000、Indirect Cost: ¥4,380,000); Fiscal Year 2011: ¥6,240,000 (Direct Cost: ¥4,800,000、Indirect Cost: ¥1,440,000); Fiscal Year 2010: ¥6,240,000 (Direct Cost: ¥4,800,000、Indirect Cost: ¥1,440,000); Fiscal Year 2009: ¥6,500,000 (Direct Cost: ¥5,000,000、Indirect Cost: ¥1,500,000)
• Keywords: 受精 / 精子活性化・誘引物質 / 精子受精能阻害物質 / 精子走化性 / 受精能獲得 / カタユウレイボヤ / マウス / 精子 / 先体反応 / 動物生理化学 / ホヤ

Research Abstract

We are aiming to elucidate of control mechanisms of sperm movement and function during fertilization. In this study, we have studied on chemotaxis of ascidian spermatozoa and regulation of sperm capacitation by seminal plasma. Finally, we have found that a plasma membrane Ca^<2+>/ATPase is involved in ascidian sperm chemotaxis. In mouse, seminal vesicle secretion 2(SVS2) is essential for regulating sperm capacitation in female genital tract.

Research Products

• [Journal Article] Mechanism Regulating Ca2+-dependent Mechanosensory Behaviour in Sea Urchin Spermatozoa (2011)
  • Author(s): Kambara Y., Shiba K., Yoshida M., Sato C., Kitajima K., & Shingyoji C.
  • Journal Title: Cell Structure and Function Volume: 36 Issue: 1 Pages: 69-82
  • DOI: 10.1247/csf.10020
  • NAID: 130004137565
  • ISSN: 0386-7196, 1347-3700
  • Peer Reviewed
• [Journal Article] Lipid rafts : keys to sperm maturation, fertilization, and early embryogenesis (2011)
  • Author(s): Kawano N, Yoshida K, Miyado K, Yoshida M
  • Journal Title: J Lipids Volume: 2011 Pages: 264706-264706
  • DOI: 10.1155/2011/264706
  • Peer Reviewed
• [Journal Article] Spermchemotaxis and regulation of flagellarmovement by Ca^<2+> (2011)
  • Author(s): Yoshida M., & Yoshida K.
  • Journal Title: Mol. Hum. Reprod Volume: 17 Issue: 8 Pages: 457-465
  • DOI: 10.1093/molehr/gar041
  • Peer Reviewed
• [Journal Article] Binding immunogl obulin protein(BiP) resolves rheumatoid synovitis : a xenogeneic study using rheumatoid arthritis synovial membrane transplants in SCID mice (2011)
  • Author(s): Yoshida K., Ochiai A., Matsuno H., Panayi G. S., & Corrigall V. M.
  • Journal Title: Arthritis Research & Therapy Volume: 13 Issue: 5
  • DOI: 10.1186/ar3463
  • Peer Reviewed
• [Journal Article] Mechanism regulating Ca^<2+>-dependent mechanosensory behaviour in sea urchin spermatozoa (2011)
  • Author(s): Kambara, Y.
  • Journal Title: Cell Structure and Function Volume: 36 Pages: 69-82
  • Peer Reviewed
• [Journal Article] Phosphorylation of the MAPK pathwayhas an essential role in the acrosome reaction inminiature pig sperm (2010)
  • Author(s): Kawano N., Ito J., Kashiwazaki N., & Yoshida M.
  • Journal Title: Reprod. Domestic Anim Volume: 45 Issue: 2 Pages: 263-268
  • DOI: 10.1111/j.1439-0531.2008.01279.x
  • Peer Reviewed
• [Journal Article] Association of Seminal Plasma Motility Inhibitors/Semenogelins with Sperm in Asthenozoospermia-Infertile Men (2010)
  • Author(s): Terai K., Yoshida K., Yoshiike M., Fujime M., & Iwamoto T.
  • Journal Title: Urologia Internationalis Volume: 85 Issue: 2 Pages: 209-215
  • DOI: 10.1159/000315976
  • Peer Reviewed
• [Journal Article] Phosphorylation of the MAPK pathway has an essential role in the acrosome reaction in miniature pig sperm. (2010)
  • Author(s): Kawano, N.
  • Journal Title: Reproduction in Domestic Animals Volume: 45 Pages: 263-268
  • Peer Reviewed
• [Journal Article] Association of seminal plasma motility inhibitors/semenogelins with sperm in asthenozoosoermia-infertile men (2010)
  • Author(s): Terai K
  • Journal Title: Urologia Internationalis Volume: 85 Pages: 209-215
  • Peer Reviewed
• [Journal Article] Lipid Rafts : Keys to Sperm Maturation, Fertilization, and Early Embrvoaenesis. (2010)
  • Author(s): Kawano, N.
  • Journal Title: Journal of Lipids Volume: 2011 Pages: 264706-264706
  • Peer Reviewed
• [Journal Article] Phosphorylation of the MAPK pathway has an essential role in the acrosome reaction in miniature pig sperm. (2010)
  • Author(s): Kawano, N.
  • Journal Title: Reproduction in Domestic Animals 45 Pages: 263-268
  • Peer Reviewed
• [Journal Article] (2010)
  • Author(s): Yoshida, K
  • Journal Title: Human Spermatozoa : Maturation, Capacitation and Abnormalities.(Nova Science Publishers, Inc.) Pages: 205-220
• [Journal Article] Functional implications of membrane modification with semenogelins for inhibition of sperm motility in humans (2009)
  • Author(s): Yoshida K., Krasznai Z. T., Krasznai Z., Yoshiike M., Kawano N., Yoshida M. Morisawa M., Toth Z., Bazsane Z.K., Marian T., & Iwamoto T.
  • Journal Title: Cell Mot. Cytoskeleton Volume: 66 Issue: 2 Pages: 99-108
  • DOI: 10.1002/cm.20329
  • Peer Reviewed
• [Journal Article] Functional implications of membrane modification with semenogelins for inhibition of sperm motility in humans (2009)
  • Author(s): Yoshida, K.
  • Journal Title: Cell Motility and the Cytoskeleton 66 Pages: 99-108
  • Peer Reviewed
• [Presentation] Sperm Chemotaxis in the Ascidian Ciona intestinalis (2012)
  • Author(s): Yoshida, M.
  • Organizer: 3rd JAMBIO forum
  • Place of Presentation: Tokyo, Japan
  • Year and Date: 2012-01-14
• [Presentation] Sperm Chemotaxis in the Ascidian Ciona intestinalis (2012)
  • Author(s): Yoshida, M.
  • Organizer: 3^<rd) JAMBIO forum
  • Place of Presentation: 東京大学理学部2号館講堂(東京都文京区)(招待講演)
  • Year and Date: 2012-01-14
• [Presentation] カタユウレイボヤ精子走化性における細胞膜型Ca^<2+>/ATPaseの役割 (2011)
  • Author(s): 中島章,松永茂,吉田薫,吉田学
  • Organizer: 第6回鞭毛・ダイニン機能研究会
  • Place of Presentation: 東京
  • Year and Date: 2011-10-01
• [Presentation] カタユウレイボヤ精子走化性における細胞膜型Ca^<2+>/ATPaseの役割 (2011)
  • Author(s): 中島章
  • Organizer: 第6回鞭毛・ダイニン機能研究会
  • Place of Presentation: 東京大学理学部2号館講堂(東京都文京区)
  • Year and Date: 2011-10-01
• [Presentation] Role of Ca^<2+> in chemotactic behavior of ascidian sperm (2011)
  • Author(s): Yoshida, M.
  • Organizer: 6^<th> Asian-Pacific Organization for Cell Biology Congress
  • Place of Presentation: EDSA Shangri-La(Manila, Philippines)
  • Year and Date: 2011-02-26
• [Presentation] Role of Ca^<2+> in chemotactic behavior of ascidian sperm (2011)
  • Author(s): Yoshida, M.
  • Organizer: 6th Asian-Pacific Organization for Cell Biology Congress
  • Place of Presentation: Manila, Philippines
• [Presentation] Sperm Chemotaxis in the Ascidian Ciona intestinalis (2011)
  • Author(s): Yoshida, M.
  • Organizer: BIT's 1st AnnualWorld Congress of Marine Biotechnology
  • Place of Presentation: Dailian, China
• [Presentation] スジキレボヤ精子活性化誘引物質の構造決定を目指した合成研究 (2011)
  • Author(s): 柴田一、土川博史、松森信明、村田道雄、大石徹、平館裕希、吉田学、森澤正昭
  • Organizer: 第99回有機合成シンポジウム
  • Place of Presentation: 慶應大薬学部(東京)
• [Presentation] Plasma membrane Ca^<2+>/ATPase acts as a SAAF receptor and regulates chemotactic response in the ascidian spermatozoa (2011)
  • Author(s): Yoshida, K., Nakashima, A., Inaba, K., and Yoshida, M.
  • Organizer: Gordon Research Conference : Fertilization and the Activation of Development
  • Place of Presentation: Plymouth, NH, USA
• [Presentation] 精嚢分泌タンパクSVS2のマウス体内受精における役割について (2011)
  • Author(s): 河野菜摘子,荒木直也,吉田薫,吉田学,宮戸健二
  • Organizer: 日本動物学会第82回大会
  • Place of Presentation: 旭川
• [Presentation] カタユウレイボヤ精子走化性における細胞膜型Ca^<2+>/ATPaseの役割 (2011)
  • Author(s): 中島章,吉田薫,吉田学
  • Organizer: 日本動物学会第82回大会
  • Place of Presentation: 旭川
• [Presentation] カタユウレイボヤ卵に於ける細胞外pH上昇による精子誘引物質の放出 (2011)
  • Author(s): 泉水奏,柴小菊,馬場昭次,稲葉一男,吉田学
  • Organizer: 日本動物学会第82回大会
  • Place of Presentation: 旭川
• [Presentation] マウス精子受精能獲得における精嚢分泌タンパク質SVSsの機能解析 (2011)
  • Author(s): 荒木直也,吉田薫,河野菜摘子,宮戸健二,吉田学
  • Organizer: 第34回日本分子生物学会年会
  • Place of Presentation: 横浜
• [Presentation] Sperm Chemotaxis in the Ascidian Ciona Intestinalis (2011)
  • Author(s): Yoshida, M.
  • Organizer: BIT'S 1st Annual World Congress of Marine Biote chnology
  • Place of Presentation: Dalian World EXPO Center (中国・大連)(招待講演)
• [Presentation] Plasma membrane Ca^<2+>/VATPase acts as a SAAF receptor and regulates chemotactic response in the ascidian spermatozoa (2011)
  • Author(s): Yoshida, M.
  • Organizer: Gordon Research Conference : Fertilization and the Activation of Development
  • Place of Presentation: Holderness School (Plymouth, NH, USA)
• [Presentation] スジキレボヤ精子活性化誘引物質の構造決定を目指した合成研究 (2011)
  • Author(s): 柴田一
  • Organizer: 第99回有機合成シンポジウム
  • Place of Presentation: 慶応大学薬学部(東京都港区)
• [Presentation] 精嚢分泌タンパクSVS2のマウス体内受精における役割について (2011)
  • Author(s): 河野菜摘子
  • Organizer: 日本動物学会第82回大会
  • Place of Presentation: 旭川クリスタルホール(旭川市)
• [Presentation] カタユウレイボヤ精子走化性における細胞膜型Ca^<2+>/ATPaseの役割 (2011)
  • Author(s): 中島章
  • Organizer: 日本動物学会第82回大会
  • Place of Presentation: 旭川クリスタルホール(旭川市)
• [Presentation] カタユウレイボヤ卵に於ける細胞外pH上昇による精子誘引物質の放出 (2011)
  • Author(s): 泉水奏
  • Organizer: 日本動物学会第82回大会
  • Place of Presentation: 旭川クリスタルホール(旭川市)
• [Presentation] マウス精子受精能獲得における精嚢分泌タンパク質SVSsの機能解析 (2011)
  • Author(s): 荒木直也
  • Organizer: 第34回日本分子生物学会年会
  • Place of Presentation: パシフィコ横浜(横浜市)
• [Presentation] TZF遺伝子欠損マウスは雄性不妊である (2011)
  • Author(s): 吉田薫
  • Organizer: 第34回日本分子生物学会年会
  • Place of Presentation: パシフィコ横浜(横浜市)
• [Presentation] マウス精子の受精能獲得抑制に対する精嚢分泌タンパク質SVS2の作用 (2010)
  • Author(s): 荒木直也
  • Organizer: 第33回日本分姓物学会年会
  • Place of Presentation: 神戸ポトーアイランド(神戸市)
  • Year and Date: 2010-12-09
• [Presentation] カタユウレイボヤ精子走化性における誘引物質受容機構 (2010)
  • Author(s): 吉田薫
  • Organizer: 第33回日本分子生物学会年会
  • Place of Presentation: 神戸ポートアイランド(神戸市)
  • Year and Date: 2010-12-09
• [Presentation] 精嚢腺タンパク質SVSsの体内受精における役割 (2010)
  • Author(s): 河野菜摘子
  • Organizer: 第33回日本分子生物学会年会
  • Place of Presentation: 神戸ポートアイランド(神戸市)
  • Year and Date: 2010-12-09
• [Presentation] Sperm chemotaxis mediated bycontrol of intracellar Ca^<2+> via plasma membrane Ca^<2+> ATPase (2010)
  • Author(s): Yoshida K.
  • Organizer: Toin International Symposium on Biomedical Engineering 2010
  • Place of Presentation: Yokohama, Japan
  • Year and Date: 2010-11-06
• [Presentation] Biodistribution of PEG-Modified Gold Nanoparticles in Mice (2010)
  • Author(s): Hatano K, Yoshida K, Hagiwara K, Miura Y, and Hagiwara H.
  • Organizer: Toin International Symposium on Biomedical Engineering 2010
  • Place of Presentation: Yokohama, Japan
  • Year and Date: 2010-11-06
• [Presentation] Localization of Andorogen Receptor Corepressor Testicular Zinc-finger Protein on Mouse Testis (2010)
  • Author(s): Sako N, Sasaki K, Kamakura S, Yamasaki K, Yoshida K, and Hagiwara H.
  • Organizer: Toin International Symposium on Biomedical Engineering 2010
  • Place of Presentation: Yokohama, Japan
  • Year and Date: 2010-11-06
• [Presentation] Sperm chemotaxis mediated by control of intercellular Ca^<2+> via plasma membrane Ca^<2+> ATPase (2010)
  • Author(s): Kaoru Yoshida
  • Organizer: 5th TOIN International Symposium on Biomedical Engineering 2010
  • Place of Presentation: TOIN Memorial Academium(Yokohama, Japan)
  • Year and Date: 2010-11-06
• [Presentation] カタユウレイボヤ精子走化性における誘引物質受容機構 (2010)
  • Author(s): 吉田学
  • Organizer: 日本動物学会第81回大会
  • Place of Presentation: 東京大学教養学部(東京都目黒区)
  • Year and Date: 2010-09-25
• [Presentation] カタユウレイボヤ精子走化性における誘引物質の受容体探索 (2010)
  • Author(s): 吉田薫,稲葉一男,吉田学
  • Organizer: 日本プロテオーム学会2010年会
  • Place of Presentation: 浦安
  • Year and Date: 2010-07-26
• [Presentation] カタユウレイボヤ精子走化性における誘引物質の受容体探索 (2010)
  • Author(s): 吉田薫
  • Organizer: 日本プロテオーム学会2010年会
  • Place of Presentation: 東京ベイホテル東急(千葉県浦安市)
  • Year and Date: 2010-07-26
• [Presentation] Mechanism of ascidian sperm chemotaxis. (2010)
  • Author(s): Yoshida, M.
  • Organizer: 11th International Symposium on Spfrmatology
  • Place of Presentation: Okinawa Convention Center(Okinawa, Japan)
  • Year and Date: 2010-06-27
• [Presentation] Function of seminal vesicle secretion proteins (SVSs) in capacitation of mouse sperm. (2010)
  • Author(s): Araki, N.
  • Organizer: 11th International Symposium on Spermatology
  • Place of Presentation: Okinawa Convention Center(Okinawa, Japan)
  • Year and Date: 2010-06-25
• [Presentation] The essential role of seminal vesicle secretions on the sperm fertility in the female reproductive tract. (2010)
  • Author(s): Kawano, N.
  • Organizer: 11th International Symposium on Spermatology
  • Place of Presentation: Okinawa Convention Center (Okinawa, Japan)
  • Year and Date: 2010-06-25
• [Presentation] Evaluation of sperm quality based on SPMIs binding on ICSI outcome. (2010)
  • Author(s): Terai, K.
  • Organizer: 11th International Symposium on Spermatology
  • Place of Presentation: Okinawa Convention Center(Okinawa, Japan)
  • Year and Date: 2010-06-25
• [Presentation] A plasma membrane Ca^<2+> ATPase is a potential candidate for the SAAF receptor (2010)
  • Author(s): Yoshida, K.
  • Organizer: 11th International Symposium on Spermatology
  • Place of Presentation: Okinawa Convention Center(Okinawa. Japan)
  • Year and Date: 2010-06-25
• [Presentation] カタユウレイボヤ精子誘引物質SAAF受容体の探索 (2010)
  • Author(s): 吉田学
  • Organizer: 第24回海洋生物活性談話会
  • Place of Presentation: 休暇村大久野島(広島県竹原市)
  • Year and Date: 2010-06-05
• [Presentation] カタユウレイボヤ精子誘引物質SAAFの精子受容体同定の試み (2010)
  • Author(s): 吉田薫,稲葉一男,吉田学
  • Organizer: 第5回鞭毛・ダイニン機能研究会
  • Place of Presentation: 東京
  • Year and Date: 2010-03-23
• [Presentation] 精嚢分泌タンパク質SVSによる精子受精能抑制機構 (2010)
  • Author(s): 荒木直也,河野菜摘子,宮戸健二,吉田薫,吉田学
  • Organizer: 第5回鞭毛・ダイニン機能研究会
  • Place of Presentation: 東京
  • Year and Date: 2010-03-23
• [Presentation] カタユウレイボヤ精子誘引物質SAAFの精子受容体同定の試み (2010)
  • Author(s): 吉田薫
  • Organizer: 第5回鞭毛・ダイニン機能研究会
  • Place of Presentation: 東大理学系研究科(東京都文京区)
  • Year and Date: 2010-03-23
• [Presentation] 精嚢分泌タンパク質SVSによる精子受精能抑制機構 (2010)
  • Author(s): 荒木直也
  • Organizer: 第5回鞭毛・ダイニン機能研究会
  • Place of Presentation: 東大理学系研究科(東京都文京区)
  • Year and Date: 2010-03-23
• [Presentation] カタユウレイボヤ精子誘引物質SAAF受容体の探索 (2010)
  • Author(s): 吉田薫,稲葉一男,大石徹,村田道雄,吉田学
  • Organizer: 第24回海洋生物活性談話会
  • Place of Presentation: 広島県竹原市
• [Presentation] Mechanism of ascidian sperm chemotaxis (2010)
  • Author(s): Yoshida, M.
  • Organizer: 11th International Symposium on Spermatology
  • Place of Presentation: Okinawa, Japan
• [Presentation] Function of seminal vesicle secretion proteins(SVSs) in capacitation of mouse sperm (2010)
  • Author(s): Araki, N., Yoshida, K., and Yoshida, M.
  • Organizer: 11th International Symposium on Spermatology
  • Place of Presentation: Okinawa, Japan
• [Presentation] The essential role of seminal vesicle secretions on the sperm fertility in the female reproductive tract (2010)
  • Author(s): Kawano, N., Araki, N., Yoshida, K., Yoshida, M., and Miyado, K.
  • Organizer: 11th International Symposium on Spermatology
  • Place of Presentation: Okinawa, Japan
• [Presentation] A plasma membrane Ca^<2+> ATPase is a potential candidate for the SAAF receptor (2010)
  • Author(s): Yoshida, K., Oishi, T., Murata, M., and Yoshida, M.
  • Organizer: 11th International Symposium on Spermatology
  • Place of Presentation: Okinawa, Japan
• [Presentation] Evaluation of sperm quality based on SPMIs binding on ICSI outcome (2010)
  • Author(s): Terai K, Yoshida K, Yoshiike M, Iwamoto T, Matsuura R, and Yoshida A.
  • Organizer: 11th International Symposium on Spermatology
  • Place of Presentation: Okinawa, Japan
• [Presentation] カタユウレイボヤ精子走化性における誘引物質受容機構 (2010)
  • Author(s): 吉田薫,稲葉一男,吉田学
  • Organizer: 日本動物学会第81回大会
  • Place of Presentation: 東京
• [Presentation] マウス精子の受精能獲得抑制に対する精嚢分泌タンパク質SVS2の作用 (2010)
  • Author(s): 荒木直也,河野菜摘子,吉田薫,宮戸健二,吉田学
  • Organizer: 第33回日本分子生物学会年会
  • Place of Presentation: 神戸
• [Presentation] 精嚢腺タンパク質SVSsの体内受精における役割 (2010)
  • Author(s): 河野菜摘子,金井誠也,荒木直也,吉田薫,吉田学,宮戸健二
  • Organizer: 第33回日本分子生物学会年会
  • Place of Presentation: 神戸
• [Presentation] カタユウレイボヤ精子走化性における誘引物質受容機構 (2010)
  • Author(s): 吉田薫,稲葉一男,吉田学
  • Organizer: 第33回日本分子生物学会年会
  • Place of Presentation: 神戸
• [Presentation] マウス精嚢由来物質による精子受精能調節機構 (2009)
  • Author(s): 吉田学
  • Organizer: 第41回精子研究会
  • Place of Presentation: 駒場
  • Year and Date: 2009-12-19
• [Presentation] マウス精嚢由来物質による精子受精能調節機構 (2009)
  • Author(s): 吉田学
  • Organizer: 第41回精子研究会
  • Place of Presentation: 東大総合文化研究科(東京都目黒区)
  • Year and Date: 2009-12-19
• [Presentation] 卵に対する精子走化性:精子の誘引物質認識と応答のメカニズム (2009)
  • Author(s): 吉田学
  • Organizer: 第32回日本分子生物学会年会
  • Place of Presentation: パシフィコ横浜(神奈川県横浜市)
  • Year and Date: 2009-12-10
• [Presentation] 卵への精子走化性における精子運動制御のメカニズム (2009)
  • Author(s): 吉田学
  • Organizer: 日本発生生物学会秋季シンポジウム
  • Place of Presentation: 東レ研修センター(静岡県三島市)
  • Year and Date: 2009-11-27
• [Presentation] Mechanism of sperm chemotaxis : How are spermatozoa guided to eggs? (2009)
  • Author(s): Yoshida, M.
  • Organizer: International Symposium on Cellular Signaling～principles and functions～
  • Place of Presentation: University of Tsukuba Tsukuba, Japan.
  • Year and Date: 2009-11-19
• [Presentation] ヒト精嚢分泌タンパク質SEMG1 & 2による精子受精能獲得過程の制御 (2009)
  • Author(s): 吉田薫
  • Organizer: 第8回受精シンポジウム・日本動物学会第80回大会
  • Place of Presentation: 静岡
  • Year and Date: 2009-09-18
• [Presentation] マウス精子受精能獲得における精嚢腺タンパク質SVSの機能解析 (2009)
  • Author(s): 荒木直也
  • Organizer: 日本動物学会第80回大会
  • Place of Presentation: グランシップ静岡(静岡県静岡市)
  • Year and Date: 2009-09-17
• [Presentation] ヒト精嚢分泌タンパク質SEMG1&2による精子受精能獲得過程の制御 (2009)
  • Author(s): 吉田薫
  • Organizer: 日本動物学会第80回大会
  • Place of Presentation: グランシップ静岡(静岡県静岡市)
  • Year and Date: 2009-09-17
• [Presentation] Role of Ca^<2+> in chemotactic behavior of ascidian sperm. (2009)
  • Author(s): Yoshida, M.
  • Organizer: Gordon Research Conference : Fertilization and the Activation of Development
  • Place of Presentation: Holderness School, Plymouth, NH, USA
  • Year and Date: 2009-07-16
• [Presentation] When do spermatozoa detect the chemoattractant? -Experimental and simulation study. (2009)
  • Author(s): Shiba, K.
  • Organizer: Gordon Research Conference : Fertilization and the Activation of Development
  • Place of Presentation: Holderness School, Plymouth, NH, USA
  • Year and Date: 2009-07-16
• [Presentation] How does the ascidian egg attract sperm? Releasing mechanisms of the sperm attractant SAAF from the egg. (2009)
  • Author(s): Yoshida, M.
  • Organizer: 5th International Tunicate Meeting
  • Place of Presentation: Okinawa Industry Support Center, Okinawa, Japan
  • Year and Date: 2009-06-21
• [Presentation] Sperm chemotactic behavior and Ca^<2+> dynamics of the ascidian, Ciona intestinalis. (2009)
  • Author(s): Shiba, K.
  • Organizer: 5th International Tunicate Meeting
  • Place of Presentation: Okinawa Industry Support Center, Okinawa, Japan
  • Year and Date: 2009-06-21
• [Presentation] ホヤ精子誘引物質と精子運動制御機構 (2009)
  • Author(s): 吉田学
  • Organizer: 第23回海洋生物活性談話会
  • Place of Presentation: 東京大学三崎臨海実験所(神奈川県三浦市)
  • Year and Date: 2009-05-23
• [Presentation] ホヤ精子誘引物質と精子運動制御機構 (2009)
  • Author(s): 吉田学,近藤江里,柴小菊,大石徹,村田道雄
  • Organizer: 第23回海洋生物活性談話会
  • Place of Presentation: 三浦
• [Presentation] How does the ascidian egg attract sperm? Releasing mechanisms of the sperm attractant SAAF from the egg (2009)
  • Author(s): Kondoh, E., Konno, A., Inaba, K., Ohishi, T., Murata, M., and Yoshida, M.
  • Organizer: 5th International Tunicate Meeting
  • Place of Presentation: Okinawa, Japan
• [Presentation] Sperm chemotactic behavior and Ca^<2+> dynamics of the ascidian, Ciona intestinalis (2009)
  • Author(s): Shiba, K., Baba, S. A, and Yoshida, M.
  • Organizer: 5th International Tunicate Meeting
  • Place of Presentation: Okinawa, Japan
• [Presentation] Role of Ca^<2+> in chemotactic behavior of ascidian sperm (2009)
  • Author(s): Maruyama, K., Shiba, K., Baba, S. A., andYoshida, M.
  • Organizer: Gordon Research Conference : Fertilization and the Activation of Development
  • Place of Presentation: Plymouth, NH, USA
• [Presentation] When do spermatozoa detect the chemoattractant?-Experimental and simulation study (2009)
  • Author(s): Shiba, K., Miyashiro, D., Kamimura, S., Baba, S. A, and Yoshida, M.
  • Organizer: Gordon Research Conference : Fertilization and the Activation of Development
  • Place of Presentation: Plymouth, NH, USA
• [Presentation] マウス精子受精能獲得における精嚢腺タンパク質SVSの機能解析 (2009)
  • Author(s): 荒木直也,吉田学,吉田薫
  • Organizer: 日本動物学会第80回大会
  • Place of Presentation: 静岡
• [Presentation] Mechanism of sperm chemotaxis : How are spermatozoa guided to eggs? (2009)
  • Author(s): Yoshida, M.
  • Organizer: International Symposium on Cellular Signaling～principles and functions～
  • Place of Presentation: Tsukuba, Japan
• [Presentation] 卵への精子走化性における精子運動制御のメカニズム (2009)
  • Author(s): 吉田学
  • Organizer: 日本発生生物学会秋季シンポジウム
  • Place of Presentation: 三島
• [Presentation] 卵に対する精子走化性:精子の誘引物質認識と応答のメカニズム (2009)
  • Author(s): 柴小菊,馬場昭次,吉田学
  • Organizer: 第32回日本分子生物学会年会
  • Place of Presentation: 横浜
• [Book] Sperm Cell Research in the 21st Century : Historical Discoveries to New Horizons. (2012)
  • Author(s): Yoshida M.
  • Publisher: Adthree Publishing Co.
• [Book] Sperm Cell Research in the 21st Century : Historical Discoveries to New Horizons (2012)
  • Author(s): Yoshida, M.
  • Publisher: Adthree Publishing Co.(in press)
• [Book] Human Spermatozoa : Maturation, Capacitation and Abnormalities. (2010)
  • Author(s): Yoshida K., Iwamoto T. & Yoshida M.
  • Publisher: Nova Science Publishers, Inc.
• [Book] Effects of the Seminal Plasma Proteins Semenogelin (SEMG)/Seminal Vesicle Secretion 2(SVS2) on Sperm Fertility."Human Spermatozoa : Maturation, Caoacitation and Abnormalities" Ed : Leieune T and Delvaux Pascal pp205-220 (2010)
  • Author(s): Yoshida K
  • Total Pages: 545
  • Publisher: Nova Science Publishers
• [Remarks]
  • URL: http://www.mmbs.s.u-tokyo.ac.jp/research/Yoshida/index.html
• [Remarks]
  • URL: http://www.mmbs.s.u-tokyo.ac.jp/research/Yoshida/index.html
• [Remarks]
  • URL: http://www.nunbs.s.u-tok-yo.ac.jp/research/Yoshida/figs/index.html